LeishMANIAdb
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Small hydrophilic protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Small hydrophilic protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H8C0_LEIBR
TriTrypDb:
LbrM.15.1520
Length:
53

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H8C0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8C0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 8 12 PF00656 0.778
DOC_WW_Pin1_4 11 16 PF00397 0.758
DOC_WW_Pin1_4 39 44 PF00397 0.781
LIG_NRP_CendR_1 50 53 PF00754 0.651
LIG_SH2_SRC 26 29 PF00017 0.652
MOD_CDK_SPxxK_3 11 18 PF00069 0.748
MOD_CK1_1 44 50 PF00069 0.688
MOD_GSK3_1 44 51 PF00069 0.650
MOD_GSK3_1 7 14 PF00069 0.779
MOD_LATS_1 31 37 PF00433 0.652
MOD_N-GLC_1 39 44 PF02516 0.676
MOD_ProDKin_1 11 17 PF00069 0.750
MOD_ProDKin_1 39 45 PF00069 0.781
TRG_ER_diLys_1 48 53 PF00400 0.649
TRG_ER_FFAT_1 20 32 PF00635 0.715

Homologs

Protein Taxonomy Sequence identity Coverage
C9ZXP6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 62% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS