Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H8B4_LEIBR

TriTrypDb:

LbrM.15.1460 , LBRM2903_150021800

Length:

125


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A4H8B4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8B4


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.675
CLV_PCSK_FUR_1	106	110	PF00082	0.672
CLV_PCSK_KEX2_1	105	107	PF00082	0.675
CLV_PCSK_KEX2_1	108	110	PF00082	0.650
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.654
DOC_MAPK_gen_1	105	113	PF00069	0.487
DOC_USP7_MATH_1	33	37	PF00917	0.673
LIG_14-3-3_CanoR_1	106	112	PF00244	0.394
LIG_BIR_II_1	1	5	PF00653	0.623
LIG_FHA_1	108	114	PF00498	0.521
LIG_FHA_1	59	65	PF00498	0.369
LIG_FHA_2	27	33	PF00498	0.534
LIG_FHA_2	95	101	PF00498	0.524
LIG_LIR_Nem_3	67	71	PF02991	0.500
LIG_Pex14_2	51	55	PF04695	0.338
LIG_SH2_CRK	10	14	PF00017	0.651
LIG_SH2_STAT5	69	72	PF00017	0.428
LIG_SH3_3	109	115	PF00018	0.534
LIG_SUMO_SIM_par_1	109	114	PF11976	0.458
LIG_TRAF2_1	82	85	PF00917	0.514
LIG_TRAF2_1	96	99	PF00917	0.486
MOD_CK2_1	94	100	PF00069	0.527
MOD_GlcNHglycan	32	36	PF01048	0.475
MOD_GlcNHglycan	46	49	PF01048	0.413
MOD_GSK3_1	33	40	PF00069	0.684
MOD_GSK3_1	90	97	PF00069	0.386
MOD_NEK2_1	1	6	PF00069	0.720
MOD_NEK2_1	64	69	PF00069	0.485
MOD_NEK2_2	9	14	PF00069	0.635
MOD_PKA_1	107	113	PF00069	0.465
MOD_Plk_1	99	105	PF00069	0.371
MOD_Plk_2-3	94	100	PF00069	0.513
MOD_Plk_4	26	32	PF00069	0.687
MOD_Plk_4	64	70	PF00069	0.494
TRG_ENDOCYTIC_2	10	13	PF00928	0.652
TRG_NLS_MonoCore_2	105	110	PF00514	0.473
TRG_NLS_MonoExtN_4	105	111	PF00514	0.471


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7L8	Leptomonas seymouri	74%	96%
A0A0S4JKC2	Bodo saltans	45%	100%
A0A1X0NUC2	Trypanosomatidae	55%	89%
A0A3R7MID2	Trypanosoma rangeli	57%	90%
A0A3S5H6W1	Leishmania donovani	86%	100%
A4HWN4	Leishmania infantum	85%	100%
E9AQE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QF33	Leishmania major	83%	100%