Glutamine--tRNA ligase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glutaminyl-tRNA synthetase, putative

Species:

Leishmania braziliensis

UniProt:

A4H8B1_LEIBR

TriTrypDb:

LbrM.15.1430 , LBRM2903_150021500

Length:

616

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	11
GO:0110165	cellular anatomical entity	1	12
GO:0005829	cytosol	2	1

Expansion

Sequence features

A4H8B1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8B1

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	12
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006399	tRNA metabolic process	7	12
GO:0006418	tRNA aminoacylation for protein translation	6	12
GO:0006425	glutaminyl-tRNA aminoacylation	7	12
GO:0006520	amino acid metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016070	RNA metabolic process	5	12
GO:0019752	carboxylic acid metabolic process	5	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034660	ncRNA metabolic process	6	12
GO:0043038	amino acid activation	4	12
GO:0043039	tRNA aminoacylation	5	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043436	oxoacid metabolic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044281	small molecule metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901564	organonitrogen compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004812	aminoacyl-tRNA ligase activity	4	12
GO:0004819	glutamine-tRNA ligase activity	5	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016874	ligase activity	2	12
GO:0016875	ligase activity, forming carbon-oxygen bonds	3	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140101	catalytic activity, acting on a tRNA	4	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	299	301	PF00675	0.213
CLV_NRD_NRD_1	332	334	PF00675	0.213
CLV_NRD_NRD_1	360	362	PF00675	0.235
CLV_NRD_NRD_1	40	42	PF00675	0.521
CLV_NRD_NRD_1	403	405	PF00675	0.213
CLV_NRD_NRD_1	430	432	PF00675	0.228
CLV_NRD_NRD_1	503	505	PF00675	0.250
CLV_PCSK_KEX2_1	299	301	PF00082	0.235
CLV_PCSK_KEX2_1	332	334	PF00082	0.216
CLV_PCSK_KEX2_1	359	361	PF00082	0.230
CLV_PCSK_KEX2_1	40	42	PF00082	0.521
CLV_PCSK_KEX2_1	403	405	PF00082	0.213
CLV_PCSK_KEX2_1	62	64	PF00082	0.568
CLV_PCSK_PC1ET2_1	332	334	PF00082	0.216
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.568
CLV_PCSK_SKI1_1	32	36	PF00082	0.419
CLV_PCSK_SKI1_1	351	355	PF00082	0.236
CLV_PCSK_SKI1_1	40	44	PF00082	0.412
CLV_PCSK_SKI1_1	45	49	PF00082	0.412
CLV_PCSK_SKI1_1	564	568	PF00082	0.193
DEG_APCC_DBOX_1	39	47	PF00400	0.427
DOC_CYCLIN_RxL_1	590	602	PF00134	0.367
DOC_MAPK_DCC_7	403	413	PF00069	0.437
DOC_MAPK_FxFP_2	97	100	PF00069	0.265
DOC_MAPK_gen_1	332	339	PF00069	0.413
DOC_MAPK_gen_1	564	574	PF00069	0.355
DOC_MAPK_MEF2A_6	332	339	PF00069	0.413
DOC_MAPK_MEF2A_6	379	388	PF00069	0.423
DOC_MAPK_MEF2A_6	492	500	PF00069	0.399
DOC_PP4_FxxP_1	347	350	PF00568	0.413
DOC_PP4_FxxP_1	424	427	PF00568	0.467
DOC_PP4_FxxP_1	97	100	PF00568	0.265
DOC_USP7_MATH_1	4	8	PF00917	0.426
DOC_USP7_UBL2_3	238	242	PF12436	0.423
DOC_USP7_UBL2_3	32	36	PF12436	0.419
DOC_USP7_UBL2_3	505	509	PF12436	0.450
DOC_WW_Pin1_4	189	194	PF00397	0.474
DOC_WW_Pin1_4	203	208	PF00397	0.370
DOC_WW_Pin1_4	361	366	PF00397	0.434
DOC_WW_Pin1_4	518	523	PF00397	0.515
DOC_WW_Pin1_4	77	82	PF00397	0.313
LIG_14-3-3_CanoR_1	209	214	PF00244	0.515
LIG_14-3-3_CanoR_1	23	29	PF00244	0.685
LIG_14-3-3_CanoR_1	351	356	PF00244	0.414
LIG_14-3-3_CanoR_1	438	443	PF00244	0.501
LIG_AP2alpha_1	442	446	PF02296	0.480
LIG_BIR_III_4	488	492	PF00653	0.455
LIG_BRCT_BRCA1_1	166	170	PF00533	0.441
LIG_BRCT_BRCA1_1	272	276	PF00533	0.515
LIG_Clathr_ClatBox_1	405	409	PF01394	0.413
LIG_deltaCOP1_diTrp_1	154	162	PF00928	0.449
LIG_deltaCOP1_diTrp_1	416	424	PF00928	0.467
LIG_DLG_GKlike_1	299	306	PF00625	0.413
LIG_FHA_1	232	238	PF00498	0.438
LIG_FHA_1	275	281	PF00498	0.413
LIG_FHA_1	324	330	PF00498	0.431
LIG_FHA_1	443	449	PF00498	0.428
LIG_FHA_1	527	533	PF00498	0.411
LIG_FHA_1	78	84	PF00498	0.411
LIG_FHA_2	134	140	PF00498	0.413
LIG_FHA_2	190	196	PF00498	0.451
LIG_FHA_2	296	302	PF00498	0.413
LIG_FHA_2	390	396	PF00498	0.487
LIG_FHA_2	519	525	PF00498	0.511
LIG_FHA_2	584	590	PF00498	0.384
LIG_FHA_2	59	65	PF00498	0.583
LIG_FHA_2	605	611	PF00498	0.595
LIG_KLC1_Yacidic_2	142	147	PF13176	0.413
LIG_KLC1_Yacidic_2	444	449	PF13176	0.480
LIG_LIR_Apic_2	421	427	PF02991	0.467
LIG_LIR_Gen_1	161	170	PF02991	0.441
LIG_LIR_Gen_1	319	325	PF02991	0.421
LIG_LIR_Gen_1	540	547	PF02991	0.515
LIG_LIR_Nem_3	161	165	PF02991	0.416
LIG_LIR_Nem_3	167	173	PF02991	0.485
LIG_LIR_Nem_3	22	28	PF02991	0.666
LIG_LIR_Nem_3	250	254	PF02991	0.429
LIG_LIR_Nem_3	266	271	PF02991	0.463
LIG_LIR_Nem_3	301	307	PF02991	0.441
LIG_LIR_Nem_3	319	323	PF02991	0.421
LIG_LIR_Nem_3	37	42	PF02991	0.431
LIG_LIR_Nem_3	540	546	PF02991	0.459
LIG_LIR_Nem_3	575	580	PF02991	0.388
LIG_MLH1_MIPbox_1	166	170	PF16413	0.441
LIG_PCNA_yPIPBox_3	238	252	PF02747	0.423
LIG_Pex14_2	442	446	PF04695	0.413
LIG_SH2_CRK	528	532	PF00017	0.422
LIG_SH2_NCK_1	363	367	PF00017	0.515
LIG_SH2_SRC	145	148	PF00017	0.413
LIG_SH2_SRC	187	190	PF00017	0.413
LIG_SH2_SRC	228	231	PF00017	0.413
LIG_SH2_SRC	258	261	PF00017	0.515
LIG_SH2_STAP1	528	532	PF00017	0.374
LIG_SH2_STAT3	169	172	PF00017	0.466
LIG_SH2_STAT5	130	133	PF00017	0.427
LIG_SH2_STAT5	145	148	PF00017	0.413
LIG_SH2_STAT5	169	172	PF00017	0.441
LIG_SH2_STAT5	187	190	PF00017	0.441
LIG_SH2_STAT5	258	261	PF00017	0.496
LIG_SH2_STAT5	303	306	PF00017	0.413
LIG_SH2_STAT5	363	366	PF00017	0.418
LIG_SH2_STAT5	447	450	PF00017	0.413
LIG_SH2_STAT5	528	531	PF00017	0.365
LIG_SH2_STAT5	579	582	PF00017	0.413
LIG_SH2_STAT5	96	99	PF00017	0.312
LIG_SH3_2	427	432	PF14604	0.437
LIG_SH3_3	256	262	PF00018	0.515
LIG_SH3_3	404	410	PF00018	0.492
LIG_SH3_3	424	430	PF00018	0.320
LIG_SH3_3	578	584	PF00018	0.437
LIG_SH3_3	605	611	PF00018	0.617
LIG_SH3_3	97	103	PF00018	0.265
LIG_SUMO_SIM_anti_2	64	70	PF11976	0.566
LIG_TRAF2_1	212	215	PF00917	0.438
LIG_TRFH_1	463	467	PF08558	0.423
LIG_UBA3_1	405	412	PF00899	0.437
MOD_CDC14_SPxK_1	206	209	PF00782	0.423
MOD_CDK_SPxK_1	203	209	PF00069	0.423
MOD_CK1_1	21	27	PF00069	0.633
MOD_CK1_1	290	296	PF00069	0.413
MOD_CK1_1	328	334	PF00069	0.413
MOD_CK1_1	513	519	PF00069	0.437
MOD_CK2_1	133	139	PF00069	0.428
MOD_CK2_1	189	195	PF00069	0.425
MOD_CK2_1	209	215	PF00069	0.320
MOD_CK2_1	295	301	PF00069	0.421
MOD_CK2_1	384	390	PF00069	0.418
MOD_CK2_1	518	524	PF00069	0.515
MOD_CK2_1	604	610	PF00069	0.587
MOD_CMANNOS	155	158	PF00535	0.213
MOD_GlcNHglycan	120	123	PF01048	0.282
MOD_GlcNHglycan	476	479	PF01048	0.213
MOD_GlcNHglycan	5	9	PF01048	0.429
MOD_GlcNHglycan	515	518	PF01048	0.280
MOD_GlcNHglycan	69	72	PF01048	0.579
MOD_GSK3_1	15	22	PF00069	0.429
MOD_GSK3_1	270	277	PF00069	0.413
MOD_GSK3_1	295	302	PF00069	0.413
MOD_GSK3_1	30	37	PF00069	0.722
MOD_GSK3_1	436	443	PF00069	0.481
MOD_GSK3_1	448	455	PF00069	0.444
MOD_GSK3_1	548	555	PF00069	0.467
MOD_GSK3_1	63	70	PF00069	0.536
MOD_N-GLC_1	209	214	PF02516	0.290
MOD_N-GLC_1	323	328	PF02516	0.213
MOD_N-GLC_1	436	441	PF02516	0.155
MOD_N-GLC_1	510	515	PF02516	0.223
MOD_NEK2_1	15	20	PF00069	0.431
MOD_NEK2_1	323	328	PF00069	0.413
MOD_NEK2_1	34	39	PF00069	0.562
MOD_NEK2_1	389	394	PF00069	0.455
MOD_NEK2_1	442	447	PF00069	0.413
MOD_NEK2_1	474	479	PF00069	0.413
MOD_NEK2_2	231	236	PF00069	0.413
MOD_PK_1	209	215	PF00069	0.480
MOD_PK_1	63	69	PF00069	0.489
MOD_PKA_1	299	305	PF00069	0.413
MOD_PKA_2	299	305	PF00069	0.413
MOD_PKA_2	491	497	PF00069	0.363
MOD_Plk_1	209	215	PF00069	0.461
MOD_Plk_1	231	237	PF00069	0.436
MOD_Plk_1	287	293	PF00069	0.413
MOD_Plk_1	318	324	PF00069	0.418
MOD_Plk_1	389	395	PF00069	0.455
MOD_Plk_1	420	426	PF00069	0.355
MOD_Plk_1	436	442	PF00069	0.327
MOD_Plk_1	510	516	PF00069	0.452
MOD_Plk_1	63	69	PF00069	0.559
MOD_Plk_2-3	452	458	PF00069	0.447
MOD_Plk_2-3	604	610	PF00069	0.455
MOD_Plk_4	299	305	PF00069	0.413
MOD_Plk_4	325	331	PF00069	0.413
MOD_Plk_4	384	390	PF00069	0.408
MOD_Plk_4	442	448	PF00069	0.437
MOD_Plk_4	491	497	PF00069	0.378
MOD_Plk_4	63	69	PF00069	0.556
MOD_ProDKin_1	189	195	PF00069	0.474
MOD_ProDKin_1	203	209	PF00069	0.370
MOD_ProDKin_1	361	367	PF00069	0.434
MOD_ProDKin_1	518	524	PF00069	0.515
MOD_ProDKin_1	77	83	PF00069	0.307
MOD_SUMO_rev_2	542	551	PF00179	0.441
TRG_DiLeu_BaEn_1	214	219	PF01217	0.515
TRG_DiLeu_BaEn_2	101	107	PF01217	0.423
TRG_DiLeu_BaLyEn_6	348	353	PF01217	0.419
TRG_ENDOCYTIC_2	28	31	PF00928	0.555
TRG_ENDOCYTIC_2	303	306	PF00928	0.413
TRG_ENDOCYTIC_2	528	531	PF00928	0.413
TRG_ENDOCYTIC_2	579	582	PF00928	0.452
TRG_ENDOCYTIC_2	96	99	PF00928	0.339
TRG_ER_diArg_1	208	211	PF00400	0.413
TRG_ER_diArg_1	358	361	PF00400	0.433
TRG_ER_diArg_1	39	41	PF00400	0.521
TRG_ER_diArg_1	403	405	PF00400	0.413
TRG_NES_CRM1_1	373	385	PF08389	0.437

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4H9	Leptomonas seymouri	32%	100%
A0A0N1PDG1	Leptomonas seymouri	87%	100%
A0A0S4JKF2	Bodo saltans	75%	100%
A0A0S4KIR8	Bodo saltans	32%	99%
A0A1X0NUJ0	Trypanosomatidae	78%	100%
A0A1X0P200	Trypanosomatidae	32%	100%
A0A3Q8IA66	Leishmania donovani	91%	100%
A0A3S7X3T9	Leishmania donovani	32%	100%
A0A422NC24	Trypanosoma rangeli	77%	100%
A0A422P0U9	Trypanosoma rangeli	33%	100%
A0RY20	Cenarchaeum symbiosum (strain A)	31%	100%
A1A8U7	Escherichia coli O1:K1 / APEC	47%	100%
A1JQH0	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	46%	100%
A1RYD7	Thermofilum pendens (strain DSM 2475 / Hrk 5)	30%	100%
A1SS83	Psychromonas ingrahamii (strain 37)	42%	100%
A2BK91	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	31%	100%
A4FXG8	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	27%	100%
A4HIR3	Leishmania braziliensis	33%	100%
A4HWN1	Leishmania infantum	91%	100%
A4I608	Leishmania infantum	32%	100%
A4SZM1	Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1)	42%	100%
A4TNX8	Yersinia pestis (strain Pestoides F)	46%	100%
A4VL72	Pseudomonas stutzeri (strain A1501)	43%	100%
A4W846	Enterobacter sp. (strain 638)	46%	100%
A4WKI4	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	29%	100%
A4XVG2	Pseudomonas mendocina (strain ymp)	43%	100%
A4YIL8	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	28%	100%
A5F2T1	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	45%	100%
A5N6Y3	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	40%	100%
A5UN79	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	29%	100%
A6T6C3	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	47%	100%
A6UP25	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	27%	100%
A6UW15	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	26%	100%
A6VFU7	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	27%	100%
A6VP11	Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)	45%	100%
A7FKU1	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	46%	100%
A7MQT2	Cronobacter sakazakii (strain ATCC BAA-894)	46%	100%
A7MT45	Vibrio campbellii (strain ATCC BAA-1116)	44%	100%
A7ZJ63	Escherichia coli O139:H28 (strain E24377A / ETEC)	47%	100%
A7ZXU0	Escherichia coli O9:H4 (strain HS)	47%	100%
A8ABI5	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	29%	100%
A8AJD6	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	48%	100%
A8GB43	Serratia proteamaculans (strain 568)	47%	100%
A8M9D7	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	29%	100%
A9A423	Nitrosopumilus maritimus (strain SCM1)	34%	100%
A9AAT7	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	27%	100%
A9CSU5	Enterocytozoon bieneusi (strain H348)	37%	89%
A9CSZ1	Enterocytozoon bieneusi (strain H348)	30%	98%
A9MKA7	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	47%	100%
A9MUG5	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	47%	100%
A9R7G5	Yersinia pestis bv. Antiqua (strain Angola)	46%	100%
B0R4Z6	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	25%	100%
B0U6D0	Xylella fastidiosa (strain M12)	41%	100%
B1IY48	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	47%	100%
B1JG85	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	46%	100%
B1L5U2	Korarchaeum cryptofilum (strain OPF8)	30%	100%
B1LLC4	Escherichia coli (strain SMS-3-5 / SECEC)	47%	100%
B1X6L3	Escherichia coli (strain K12 / DH10B)	47%	100%
B1XW11	Polynucleobacter necessarius subsp. necessarius (strain STIR1)	43%	100%
B2K8A4	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	46%	100%
B2TU51	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	47%	100%
B2U846	Ralstonia pickettii (strain 12J)	43%	100%
B2VBN3	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	44%	100%
B3R5N3	Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)	44%	100%
B4EV71	Proteus mirabilis (strain HI4320)	46%	100%
B4RYH7	Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)	44%	100%
B4SYN9	Salmonella newport (strain SL254)	47%	100%
B4TB84	Salmonella heidelberg (strain SL476)	47%	100%
B4TQ00	Salmonella schwarzengrund (strain CVM19633)	47%	100%
B5BCC3	Salmonella paratyphi A (strain AKU_12601)	47%	100%
B5EZC3	Salmonella agona (strain SL483)	47%	100%
B5FC12	Aliivibrio fischeri (strain MJ11)	44%	100%
B5FNC1	Salmonella dublin (strain CT_02021853)	47%	100%
B5QWD0	Salmonella enteritidis PT4 (strain P125109)	47%	100%
B5R651	Salmonella gallinarum (strain 287/91 / NCTC 13346)	47%	100%
B5XZG7	Klebsiella pneumoniae (strain 342)	47%	100%
B5YQM4	Escherichia coli O157:H7 (strain EC4115 / EHEC)	47%	100%
B6EHL7	Aliivibrio salmonicida (strain LFI1238)	44%	100%
B6HYN9	Escherichia coli (strain SE11)	47%	100%
B6YSY7	Thermococcus onnurineus (strain NA1)	29%	100%
B7L9L7	Escherichia coli (strain 55989 / EAEC)	47%	100%
B7LKT3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	47%	100%
B7M5J8	Escherichia coli O8 (strain IAI1)	47%	100%
B7MFU7	Escherichia coli O45:K1 (strain S88 / ExPEC)	47%	100%
B7MPI5	Escherichia coli O81 (strain ED1a)	47%	100%
B7N9S6	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	47%	100%
B7NMN1	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	47%	100%
B7UKW1	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	47%	100%
B7VB85	Pseudomonas aeruginosa (strain LESB58)	43%	100%
B7VIH6	Vibrio atlanticus (strain LGP32)	45%	100%
B8D7U5	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)	41%	100%
B8D9J3	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)	41%	100%
C0PWA7	Salmonella paratyphi C (strain RKS4594)	47%	100%
C1DHE5	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	43%	100%
C3LTP5	Vibrio cholerae serotype O1 (strain M66-2)	45%	100%
C4K4J9	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	44%	100%
C4L887	Tolumonas auensis (strain DSM 9187 / TA4)	44%	100%
C4V819	Nosema ceranae (strain BRL01)	41%	89%
C4VBI7	Nosema ceranae (strain BRL01)	31%	100%
C4ZWF6	Escherichia coli (strain K12 / MC4100 / BW2952)	47%	100%
C5BGA4	Edwardsiella ictaluri (strain 93-146)	45%	100%
C6DBY6	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	45%	100%
C9ZRD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
C9ZXQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	93%
E9AQD9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9B199	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
G9N4A3	Hypocrea virens (strain Gv29-8 / FGSC 10586)	39%	95%
O13775	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	86%
O26157	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	28%	100%
O29979	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	32%	100%
O59314	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	32%	100%
O62431	Caenorhabditis elegans	43%	78%
O82462	Arabidopsis thaliana	32%	86%
P00962	Escherichia coli (strain K12)	47%	100%
P13188	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	76%
P14325	Dictyostelium discoideum	51%	79%
P43831	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	45%	100%
P46655	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	87%
P47897	Homo sapiens	44%	79%
P52780	Lupinus luteus	47%	78%
P56926	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	36%	72%
P56927	Neisseria meningitidis serogroup B (strain MC58)	43%	100%
P57000	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	43%	100%
P57490	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	41%	100%
P57847	Pasteurella multocida (strain Pm70)	44%	100%
P95968	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	30%	100%
Q02KT5	Pseudomonas aeruginosa (strain UCBPP-PA14)	43%	100%
Q0K808	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	44%	100%
Q0SVB1	Clostridium perfringens (strain SM101 / Type A)	44%	100%
Q0T6S8	Shigella flexneri serotype 5b (strain 8401)	47%	100%
Q0TK03	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	47%	100%
Q0TTG1	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	45%	100%
Q0W8L2	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	27%	100%
Q15TT6	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)	44%	100%
Q188C8	Clostridioides difficile (strain 630)	40%	100%
Q18GA5	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	27%	100%
Q1C540	Yersinia pestis bv. Antiqua (strain Antiqua)	46%	100%
Q1CKN4	Yersinia pestis bv. Antiqua (strain Nepal516)	46%	100%
Q1LQ72	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)	43%	100%
Q1QMM1	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	43%	100%
Q1REN7	Escherichia coli (strain UTI89 / UPEC)	47%	100%
Q2KVX0	Bordetella avium (strain 197N)	43%	100%
Q2NFU2	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	30%	100%
Q2NUP0	Sodalis glossinidius (strain morsitans)	45%	100%
Q2NZL7	Xanthomonas oryzae pv. oryzae (strain MAFF 311018)	40%	100%
Q324M4	Shigella boydii serotype 4 (strain Sb227)	47%	100%
Q32IQ0	Shigella dysenteriae serotype 1 (strain Sd197)	47%	100%
Q3BX52	Xanthomonas campestris pv. vesicatoria (strain 85-10)	39%	100%
Q3IGW8	Pseudoalteromonas translucida (strain TAC 125)	43%	100%
Q3IPL2	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	26%	100%
Q3MHH4	Bos taurus	44%	79%
Q3SRI8	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	41%	100%
Q3Z4C0	Shigella sonnei (strain Ss046)	47%	100%
Q47Z40	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	42%	100%
Q4J8P2	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	31%	100%
Q4Q6W5	Leishmania major	32%	100%
Q4QF36	Leishmania major	91%	100%
Q4QK64	Haemophilus influenzae (strain 86-028NP)	45%	100%
Q4UR70	Xanthomonas campestris pv. campestris (strain 8004)	39%	100%
Q50543	Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)	29%	100%
Q54KB8	Dictyostelium discoideum	32%	81%
Q57RP8	Salmonella choleraesuis (strain SC-B67)	47%	100%
Q58772	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	28%	100%
Q5E6P2	Aliivibrio fischeri (strain ATCC 700601 / ES114)	44%	100%
Q5F7G0	Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)	43%	100%
Q5GWF4	Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)	40%	100%
Q5PCH8	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	47%	100%
Q5QXQ2	Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)	44%	100%
Q66DC5	Yersinia pseudotuberculosis serotype I (strain IP32953)	46%	100%
Q66H61	Rattus norvegicus	44%	79%
Q6D7J7	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	45%	100%
Q6LTD1	Photobacterium profundum (strain SS9)	44%	100%
Q6LYI0	Methanococcus maripaludis (strain S2 / LL)	27%	100%
Q7MMQ4	Vibrio vulnificus (strain YJ016)	45%	100%
Q7N743	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	44%	100%
Q7NX86	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	40%	100%
Q7UX42	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	42%	100%
Q7VLM3	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	45%	100%
Q7VU94	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	41%	100%
Q7W4T0	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	41%	100%
Q7WGA6	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	41%	100%
Q81ZS7	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	46%	100%
Q83LY4	Shigella flexneri	47%	100%
Q87DU6	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	41%	100%
Q87RG4	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	46%	100%
Q87YQ1	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	42%	100%
Q88IU5	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	43%	100%
Q89AD4	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	40%	100%
Q89KR6	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	43%	100%
Q8BML9	Mus musculus	44%	79%
Q8EG26	Shewanella oneidensis (strain MR-1)	44%	100%
Q8FJW4	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	47%	100%
Q8K9E1	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	40%	100%
Q8PCB3	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	39%	100%
Q8PNZ5	Xanthomonas axonopodis pv. citri (strain 306)	39%	100%
Q8SR10	Encephalitozoon cuniculi (strain GB-M1)	42%	88%
Q8SSE4	Encephalitozoon cuniculi (strain GB-M1)	34%	96%
Q8TT52	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	27%	100%
Q8TXB7	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	29%	100%
Q8U064	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	31%	100%
Q8W4F3	Arabidopsis thaliana	50%	77%
Q8X9H8	Escherichia coli O157:H7	47%	100%
Q8XMP3	Clostridium perfringens (strain 13 / Type A)	45%	100%
Q8Y199	Ralstonia solanacearum (strain GMI1000)	43%	100%
Q8Z8F8	Salmonella typhi	47%	100%
Q8ZDD9	Yersinia pestis	46%	100%
Q8ZQX5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	47%	100%
Q971D0	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	31%	100%
Q9HQI1	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	25%	100%
Q9I2U8	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	43%	100%
Q9KTA6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	45%	100%
Q9PDP1	Xylella fastidiosa (strain 9a5c)	40%	100%
Q9V1E3	Pyrococcus abyssi (strain GE5 / Orsay)	31%	100%
Q9Y105	Drosophila melanogaster	45%	79%
Q9Y7Y8	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	76%
Q9Y9H1	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	28%	100%
V5B4P6	Trypanosoma cruzi	77%	100%
V5BSE6	Trypanosoma cruzi	32%	100%