Putative actin-related protein 3

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

actin-related protein 3, putative

Species:

Leishmania braziliensis

UniProt:

A4H8A4_LEIBR

TriTrypDb:

LbrM.15.1360 , LBRM2903_150020600

Length:

348

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0043226	organelle	2	10
GO:0110165	cellular anatomical entity	1	10
GO:0005885	Arp2/3 protein complex	2	2
GO:0032991	protein-containing complex	1	2

Expansion

Sequence features

A4H8A4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8A4

Function

Biological processes
Term	Name	Level	Count
GO:0007015	actin filament organization	5	2
GO:0009987	cellular process	1	2
GO:0016043	cellular component organization	3	2
GO:0034314	Arp2/3 complex-mediated actin nucleation	7	2
GO:0045010	actin nucleation	6	2
GO:0071840	cellular component organization or biogenesis	2	2
GO:0097435	supramolecular fiber organization	4	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	1
GO:0005488	binding	1	1
GO:0005524	ATP binding	5	1
GO:0017076	purine nucleotide binding	4	1
GO:0030554	adenyl nucleotide binding	5	1
GO:0032553	ribonucleotide binding	3	1
GO:0032555	purine ribonucleotide binding	4	1
GO:0032559	adenyl ribonucleotide binding	5	1
GO:0035639	purine ribonucleoside triphosphate binding	4	1
GO:0036094	small molecule binding	2	1
GO:0043167	ion binding	2	1
GO:0043168	anion binding	3	1
GO:0097159	organic cyclic compound binding	2	1
GO:0097367	carbohydrate derivative binding	2	1
GO:1901265	nucleoside phosphate binding	3	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.272
CLV_NRD_NRD_1	246	248	PF00675	0.218
CLV_NRD_NRD_1	33	35	PF00675	0.152
CLV_NRD_NRD_1	8	10	PF00675	0.299
CLV_PCSK_KEX2_1	119	121	PF00082	0.272
CLV_PCSK_KEX2_1	246	248	PF00082	0.217
CLV_PCSK_KEX2_1	267	269	PF00082	0.241
CLV_PCSK_KEX2_1	33	35	PF00082	0.152
CLV_PCSK_KEX2_1	8	10	PF00082	0.303
CLV_PCSK_PC1ET2_1	267	269	PF00082	0.236
CLV_PCSK_SKI1_1	274	278	PF00082	0.170
CLV_PCSK_SKI1_1	9	13	PF00082	0.359
DOC_MAPK_gen_1	57	65	PF00069	0.352
DOC_PP2B_LxvP_1	204	207	PF13499	0.389
DOC_PP2B_LxvP_1	216	219	PF13499	0.556
DOC_PP4_FxxP_1	68	71	PF00568	0.519
DOC_USP7_MATH_1	217	221	PF00917	0.463
DOC_WW_Pin1_4	319	324	PF00397	0.437
DOC_WW_Pin1_4	49	54	PF00397	0.472
LIG_14-3-3_CanoR_1	246	250	PF00244	0.467
LIG_14-3-3_CanoR_1	314	323	PF00244	0.496
LIG_14-3-3_CanoR_1	8	12	PF00244	0.221
LIG_deltaCOP1_diTrp_1	19	27	PF00928	0.415
LIG_FHA_1	101	107	PF00498	0.444
LIG_FHA_1	127	133	PF00498	0.417
LIG_FHA_1	221	227	PF00498	0.364
LIG_FHA_1	280	286	PF00498	0.434
LIG_FHA_1	325	331	PF00498	0.358
LIG_FHA_1	58	64	PF00498	0.421
LIG_FHA_1	90	96	PF00498	0.444
LIG_FHA_2	50	56	PF00498	0.472
LIG_LIR_Apic_2	66	71	PF02991	0.519
LIG_LIR_Gen_1	19	26	PF02991	0.426
LIG_LIR_Gen_1	198	207	PF02991	0.417
LIG_LIR_Gen_1	248	255	PF02991	0.374
LIG_LIR_Gen_1	62	73	PF02991	0.417
LIG_LIR_Nem_3	198	204	PF02991	0.417
LIG_LIR_Nem_3	225	230	PF02991	0.352
LIG_LIR_Nem_3	24	30	PF02991	0.531
LIG_LIR_Nem_3	248	253	PF02991	0.428
LIG_LIR_Nem_3	62	68	PF02991	0.417
LIG_Pex14_1	27	31	PF04695	0.519
LIG_SH2_CRK	250	254	PF00017	0.397
LIG_SH2_GRB2like	250	253	PF00017	0.502
LIG_SH2_NCK_1	112	116	PF00017	0.426
LIG_SH2_SRC	250	253	PF00017	0.502
LIG_SH2_STAP1	112	116	PF00017	0.352
LIG_SH2_STAP1	195	199	PF00017	0.420
LIG_SH2_STAP1	201	205	PF00017	0.413
LIG_SH2_STAP1	250	254	PF00017	0.502
LIG_SH2_STAP1	298	302	PF00017	0.435
LIG_SH2_STAP1	305	309	PF00017	0.448
LIG_SH2_STAP1	325	329	PF00017	0.514
LIG_SH2_STAT5	131	134	PF00017	0.517
LIG_SH2_STAT5	264	267	PF00017	0.352
LIG_TYR_ITIM	199	204	PF00017	0.352
LIG_WRC_WIRS_1	65	70	PF05994	0.417
MOD_CK1_1	220	226	PF00069	0.505
MOD_CK1_1	328	334	PF00069	0.412
MOD_CK2_1	49	55	PF00069	0.526
MOD_CK2_1	7	13	PF00069	0.163
MOD_GlcNHglycan	255	258	PF01048	0.251
MOD_GlcNHglycan	287	290	PF01048	0.259
MOD_GlcNHglycan	316	319	PF01048	0.345
MOD_GlcNHglycan	326	330	PF01048	0.364
MOD_GlcNHglycan	97	100	PF01048	0.303
MOD_GSK3_1	172	179	PF00069	0.527
MOD_GSK3_1	182	189	PF00069	0.440
MOD_GSK3_1	218	225	PF00069	0.391
MOD_GSK3_1	253	260	PF00069	0.354
MOD_GSK3_1	324	331	PF00069	0.450
MOD_NEK2_1	126	131	PF00069	0.352
MOD_NEK2_1	64	69	PF00069	0.417
MOD_NEK2_1	74	79	PF00069	0.417
MOD_NEK2_1	82	87	PF00069	0.417
MOD_NEK2_2	245	250	PF00069	0.401
MOD_PIKK_1	100	106	PF00454	0.472
MOD_PIKK_1	126	132	PF00454	0.519
MOD_PIKK_1	303	309	PF00454	0.558
MOD_PIKK_1	74	80	PF00454	0.503
MOD_PKA_2	182	188	PF00069	0.405
MOD_PKA_2	245	251	PF00069	0.352
MOD_PKA_2	279	285	PF00069	0.352
MOD_PKA_2	7	13	PF00069	0.221
MOD_Plk_1	126	132	PF00069	0.519
MOD_Plk_1	325	331	PF00069	0.427
MOD_Plk_4	206	212	PF00069	0.531
MOD_Plk_4	222	228	PF00069	0.324
MOD_ProDKin_1	319	325	PF00069	0.437
MOD_ProDKin_1	49	55	PF00069	0.472
MOD_SUMO_rev_2	169	178	PF00179	0.352
TRG_ENDOCYTIC_2	159	162	PF00928	0.354
TRG_ENDOCYTIC_2	201	204	PF00928	0.417
TRG_ENDOCYTIC_2	250	253	PF00928	0.397
TRG_ER_diArg_1	119	121	PF00400	0.472
TRG_ER_diArg_1	33	35	PF00400	0.352

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2F8	Leptomonas seymouri	30%	97%
A0A0N0P696	Leptomonas seymouri	26%	85%
A0A0N0P781	Leptomonas seymouri	53%	76%
A0A0N0P8M2	Leptomonas seymouri	28%	80%
A0A0N1I0W8	Leptomonas seymouri	23%	81%
A0A0N1IM09	Leptomonas seymouri	24%	75%
A0A0S4IP23	Bodo saltans	24%	86%
A0A0S4ISP2	Bodo saltans	32%	89%
A0A0S4IWZ2	Bodo saltans	27%	88%
A0A0S4JB16	Bodo saltans	27%	88%
A0A0S4JGI9	Bodo saltans	39%	83%
A0A0S4JGK8	Bodo saltans	24%	88%
A0A0S4JN99	Bodo saltans	25%	89%
A0A0S4JSR2	Bodo saltans	29%	93%
A0A0S4KJ86	Bodo saltans	25%	100%
A0A1L8EV45	Xenopus laevis	35%	83%
A0A1X0NIU0	Trypanosomatidae	27%	89%
A0A1X0NKR1	Trypanosomatidae	29%	93%
A0A1X0NPN8	Trypanosomatidae	25%	85%
A0A1X0NRG7	Trypanosomatidae	32%	90%
A0A1X0NU35	Trypanosomatidae	25%	84%
A0A1X0NVG9	Trypanosomatidae	40%	84%
A0A1X0P3H1	Trypanosomatidae	24%	86%
A0A1X0P6E4	Trypanosomatidae	25%	87%
A0A3Q8ICD3	Leishmania donovani	78%	86%
A0A3Q8IEK0	Leishmania donovani	24%	89%
A0A3Q8IGA6	Leishmania donovani	25%	86%
A0A3R7JX14	Trypanosoma rangeli	35%	90%
A0A3R7KB53	Trypanosoma rangeli	39%	84%
A0A3R7M5N2	Trypanosoma rangeli	27%	92%
A0A3S5IQV3	Trypanosoma rangeli	25%	87%
A0A3S7WTM5	Leishmania donovani	24%	79%
A0A422MY22	Trypanosoma rangeli	29%	93%
A0A422NGD7	Trypanosoma rangeli	25%	81%
A0A422NI92	Trypanosoma rangeli	23%	83%
A0A422NRB8	Trypanosoma rangeli	24%	81%
A0A422P3Z5	Trypanosoma rangeli	29%	89%
A2AKE7	Mus musculus	28%	100%
A2BDB0	Xenopus laevis	29%	93%
A2WNB0	Oryza sativa subsp. indica	22%	81%
A2X6S3	Oryza sativa subsp. indica	36%	81%
A2XLF2	Oryza sativa subsp. indica	28%	92%
A2XMK6	Oryza sativa subsp. indica	26%	97%
A2XNS1	Oryza sativa subsp. indica	28%	92%
A2YR10	Oryza sativa subsp. indica	24%	79%
A2YUL5	Oryza sativa subsp. indica	27%	89%
A3ANB5	Oryza sativa subsp. japonica	26%	97%
A3C6D7	Oryza sativa subsp. japonica	29%	92%
A4FUX8	Bos taurus	23%	82%
A4HA61	Leishmania braziliensis	24%	95%
A4HPJ8	Leishmania braziliensis	24%	86%
A4HSC2	Leishmania infantum	29%	93%
A4HWL8	Leishmania infantum	24%	79%
A4HWM4	Leishmania infantum	78%	86%
A4HYD8	Leishmania infantum	24%	89%
A4ID66	Leishmania infantum	25%	86%
A4IFE3	Bos taurus	29%	93%
A5DQP9	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	28%	97%
A7MB62	Bos taurus	26%	88%
C6KJC7	Leishmania donovani	29%	93%
C9ZXR3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	84%
C9ZXR9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	83%
C9ZYB5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	93%
C9ZYB6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	86%
D0A0S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	87%
D0A6N1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	80%
D0A8L6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	88%
D0LWX4	Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)	28%	92%
E9AKA4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	97%
E9AQC5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	79%
E9AQD1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	86%
E9AS71	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	72%
E9ATB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	86%
O00937	Sterkiella cavicola	30%	93%
O13419	Botryotinia fuckeliana	29%	93%
O15998	Ciona savignyi	29%	92%
O16808	Mayetiola destructor	29%	93%
O17320	Crassostrea gigas	29%	93%
O17502	Branchiostoma lanceolatum	28%	92%
O17503	Branchiostoma lanceolatum	28%	93%
O18499	Saccoglossus kowalevskii	29%	93%
O18500	Saccoglossus kowalevskii	28%	93%
O18840	Canis lupus familiaris	29%	93%
O42161	Salmo salar	29%	93%
O65314	Scherffelia dubia	30%	92%
O65315	Coleochaete scutata	29%	92%
O65316	Mesostigma viride	28%	92%
O73723	Takifugu rubripes	35%	83%
O74258	Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1)	29%	93%
O81221	Gossypium hirsutum	29%	92%
O93400	Xenopus laevis	29%	93%
O94241	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	87%
O94630	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	92%
O94805	Homo sapiens	23%	82%
O96019	Homo sapiens	23%	81%
O96621	Dictyostelium discoideum	26%	89%
P02572	Drosophila melanogaster	29%	93%
P02574	Drosophila melanogaster	28%	93%
P02576	Physarum polycephalum	29%	93%
P02578	Acanthamoeba castellanii	29%	93%
P02580	Glycine max	27%	93%
P02581	Glycine max	26%	92%
P02582	Zea mays	29%	93%
P02583	Oxytricha fallax	29%	97%
P04751	Xenopus laevis	29%	92%
P04752	Xenopus laevis	29%	92%
P04829	Bombyx mori	30%	93%
P07828	Dictyostelium discoideum	29%	92%
P07829	Dictyostelium discoideum	29%	93%
P07830	Dictyostelium discoideum	29%	93%
P07836	Bombyx mori	28%	93%
P07837	Bombyx mori	28%	93%
P08023	Gallus gallus	29%	92%
P0C539	Oryza sativa subsp. indica	29%	92%
P0C540	Oryza sativa subsp. japonica	28%	93%
P0C542	Oryza sativa subsp. indica	28%	93%
P0CJ46	Arabidopsis thaliana	28%	92%
P0CJ47	Arabidopsis thaliana	28%	92%
P0DM41	Caenorhabditis elegans	30%	93%
P0DM42	Caenorhabditis elegans	30%	93%
P10365	Thermomyces lanuginosus	29%	93%
P10981	Drosophila melanogaster	28%	93%
P10984	Caenorhabditis elegans	30%	93%
P10986	Caenorhabditis elegans	30%	93%
P10987	Drosophila melanogaster	29%	93%
P10988	Plasmodium falciparum (isolate NF54)	29%	93%
P10989	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	93%
P10990	Mesocentrotus franciscanus	29%	93%
P10992	Tetrahymena thermophila	29%	93%
P10993	Tetrahymena pyriformis	28%	93%
P10995	Xenopus laevis	29%	92%
P11426	Entamoeba histolytica	30%	93%
P12431	Strongylocentrotus purpuratus	28%	93%
P12432	Trypanosoma brucei brucei	28%	93%
P12433	Trypanosoma brucei brucei	28%	93%
P12715	Sterkiella nova	29%	93%
P12716	Pisaster ochraceus	29%	93%
P12717	Pisaster ochraceus	28%	93%
P13363	Phytophthora megasperma	29%	93%
P14235	Candida albicans	29%	93%
P14883	Plasmodium falciparum (isolate NF54)	28%	93%
P15475	Xenopus borealis	29%	93%
P17126	Hydra vulgaris	29%	93%
P17128	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	93%
P17304	Aplysia californica	29%	93%
P18499	Strongylocentrotus purpuratus	28%	93%
P18600	Artemia sp.	28%	93%
P18601	Artemia sp.	28%	93%
P18602	Artemia sp.	29%	100%
P18603	Artemia sp.	29%	93%
P20359	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	93%
P20360	Euplotes crassus	29%	92%
P20399	Xenopus tropicalis	29%	92%
P20904	Volvox carteri	30%	92%
P22131	Phytophthora infestans	29%	93%
P22132	Phytophthora infestans	29%	93%
P23343	Daucus carota	28%	92%
P23344	Daucus carota	26%	91%
P24263	Physarum polycephalum	29%	95%
P26182	Achlya bisexualis	28%	93%
P26183	Cryptosporidium parvum	28%	93%
P26197	Absidia glauca	28%	92%
P26198	Styela clava	28%	92%
P27130	Halocynthia roretzi	28%	92%
P27131	Naegleria fowleri	30%	93%
P27132	Naegleria fowleri	28%	94%
P29751	Oryctolagus cuniculus	29%	93%
P30161	Costaria costata	28%	100%
P30162	Onchocerca volvulus	30%	93%
P30163	Onchocerca volvulus	30%	93%
P30164	Pisum sativum	29%	93%
P30165	Pisum sativum	29%	93%
P30167	Solanum tuberosum	29%	92%
P30168	Solanum tuberosum	29%	92%
P30169	Solanum tuberosum	27%	92%
P30171	Solanum tuberosum	29%	92%
P30172	Solanum tuberosum	28%	97%
P30173	Solanum tuberosum	28%	92%
P32381	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	89%
P32390	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	81%
P32392	Drosophila melanogaster	35%	83%
P35432	Echinococcus granulosus	29%	93%
P38673	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	92%
P38696	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	91%
P41112	Podocoryna carnea	29%	93%
P41113	Podocoryna carnea	29%	93%
P41339	Limulus polyphemus	28%	93%
P41340	Limulus polyphemus	29%	93%
P41341	Limulus polyphemus	28%	93%
P42023	Pneumocystis carinii	28%	90%
P42025	Homo sapiens	29%	93%
P42528	Dictyostelium discoideum	36%	83%
P43239	Pneumocystis carinii	28%	93%
P45520	Leishmania major	30%	93%
P45521	Procambarus clarkii	28%	100%
P45885	Bactrocera dorsalis	28%	93%
P45886	Bactrocera dorsalis	28%	93%
P45887	Bactrocera dorsalis	28%	93%
P45888	Drosophila melanogaster	25%	87%
P45889	Drosophila melanogaster	28%	93%
P45890	Drosophila melanogaster	23%	87%
P45891	Drosophila melanogaster	28%	93%
P46258	Pisum sativum	28%	92%
P47117	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	78%
P48465	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	28%	93%
P48975	Cricetulus griseus	29%	93%
P49055	Carassius auratus	29%	92%
P49128	Aedes aegypti	29%	93%
P49871	Manduca sexta	28%	93%
P50138	Puccinia graminis	27%	93%
P51775	Giardia intestinalis	28%	93%
P53455	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	29%	93%
P53456	Dibothriocephalus dendriticus	30%	93%
P53457	Dibothriocephalus dendriticus	30%	92%
P53458	Dibothriocephalus dendriticus	29%	94%
P53459	Dibothriocephalus dendriticus	29%	93%
P53460	Halocynthia roretzi	29%	92%
P53461	Halocynthia roretzi	29%	93%
P53463	Heliocidaris erythrogramma	29%	93%
P53464	Heliocidaris tuberculata	29%	93%
P53465	Lytechinus pictus	29%	93%
P53466	Lytechinus pictus	29%	93%
P53467	Molgula oculata	28%	92%
P53468	Oxytricha trifallax	30%	93%
P53469	Oxytricha trifallax	30%	93%
P53470	Schistosoma mansoni	29%	93%
P53471	Schistosoma mansoni	30%	93%
P53472	Strongylocentrotus purpuratus	29%	93%
P53473	Strongylocentrotus purpuratus	29%	93%
P53474	Strongylocentrotus purpuratus	28%	93%
P53475	Styela clava	28%	92%
P53476	Toxoplasma gondii	31%	93%
P53477	Trypanosoma cruzi	29%	93%
P53478	Gallus gallus	29%	93%
P53479	Cyprinus carpio	29%	92%
P53480	Takifugu rubripes	29%	92%
P53482	Takifugu rubripes	29%	92%
P53483	Takifugu rubripes	28%	93%
P53485	Takifugu rubripes	29%	93%
P53486	Takifugu rubripes	29%	93%
P53487	Acanthamoeba castellanii	27%	90%
P53488	Gallus gallus	26%	88%
P53489	Caenorhabditis elegans	29%	88%
P53490	Acanthamoeba castellanii	34%	81%
P53491	Acetabularia peniculus	28%	99%
P53492	Arabidopsis thaliana	29%	92%
P53494	Arabidopsis thaliana	28%	92%
P53496	Arabidopsis thaliana	28%	92%
P53497	Arabidopsis thaliana	28%	92%
P53498	Chlamydomonas reinhardtii	30%	92%
P53499	Chondrus crispus	30%	93%
P53500	Cyanidioschyzon merolae (strain NIES-3377 / 10D)	31%	92%
P53501	Drosophila melanogaster	28%	93%
P53502	Fucus distichus	28%	93%
P53503	Oxytricha fallax	28%	97%
P53504	Sorghum bicolor	28%	92%
P53505	Xenopus laevis	29%	93%
P53506	Xenopus laevis	29%	93%
P53689	Phaffia rhodozyma	28%	93%
P55805	Sterkiella nova	29%	93%
P60009	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	29%	93%
P60010	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	93%
P60011	Saccharomyces bayanus	29%	93%
P60706	Gallus gallus	29%	93%
P60707	Trichosurus vulpecula	29%	93%
P60708	Equus caballus	29%	93%
P60709	Homo sapiens	29%	93%
P60710	Mus musculus	29%	93%
P60711	Rattus norvegicus	29%	93%
P60712	Bos taurus	29%	93%
P60713	Ovis aries	29%	93%
P61157	Bos taurus	35%	83%
P61158	Homo sapiens	35%	83%
P61160	Homo sapiens	26%	88%
P61161	Mus musculus	26%	88%
P61162	Canis lupus familiaris	28%	93%
P61163	Homo sapiens	28%	93%
P61164	Mus musculus	28%	93%
P62736	Homo sapiens	29%	92%
P62737	Mus musculus	29%	92%
P62738	Rattus norvegicus	29%	92%
P62739	Bos taurus	29%	92%
P62740	Oryctolagus cuniculus	29%	92%
P63256	Anser anser anser	29%	93%
P63257	Trichosurus vulpecula	29%	93%
P63258	Bos taurus	29%	93%
P63259	Rattus norvegicus	29%	93%
P63260	Mus musculus	29%	93%
P63261	Homo sapiens	29%	93%
P63267	Homo sapiens	29%	93%
P63268	Mus musculus	29%	93%
P63269	Rattus norvegicus	29%	93%
P63270	Gallus gallus	29%	93%
P68032	Homo sapiens	29%	92%
P68033	Mus musculus	29%	92%
P68034	Gallus gallus	29%	92%
P68035	Rattus norvegicus	29%	92%
P68133	Homo sapiens	29%	92%
P68134	Mus musculus	29%	92%
P68135	Oryctolagus cuniculus	29%	92%
P68136	Rattus norvegicus	29%	92%
P68137	Sus scrofa	29%	92%
P68138	Bos taurus	29%	92%
P68139	Gallus gallus	29%	92%
P68140	Takifugu rubripes	28%	92%
P68142	Takifugu rubripes	29%	93%
P68143	Oreochromis mossambicus	29%	93%
P68264	Oreochromis mossambicus	28%	92%
P68555	Taenia solium	30%	93%
P68556	Dibothriocephalus dendriticus	30%	93%
P69002	Heliocidaris erythrogramma	29%	93%
P69003	Heliocidaris tuberculata	29%	93%
P69004	Mesocentrotus franciscanus	29%	93%
P69005	Strongylocentrotus purpuratus	29%	93%
P78711	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	29%	93%
P78712	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	79%
P79818	Oryzias latipes	29%	93%
P81228	Solanum tuberosum	31%	100%
P81229	Solanum tuberosum	32%	100%
P83750	Cyprinus carpio	29%	93%
P83751	Ctenopharyngodon idella	29%	93%
P83967	Drosophila melanogaster	28%	93%
P83968	Drosophila simulans	28%	93%
P83969	Bactrocera dorsalis	28%	93%
P84183	Bombyx mori	29%	93%
P84184	Helicoverpa armigera	29%	93%
P84185	Anopheles gambiae	29%	93%
P84336	Camelus dromedarius	29%	93%
P84856	Chlorocebus pygerythrus	29%	96%
P85515	Rattus norvegicus	28%	93%
P86173	Rattus norvegicus	23%	82%
P86287	Plasmodium falciparum (isolate HB3)	29%	93%
P86288	Plasmodium falciparum (isolate HB3)	28%	93%
P90689	Brugia malayi	29%	93%
P91754	Lumbricus rubellus	29%	94%
P92176	Lumbricus terrestris	29%	93%
P92179	Biomphalaria glabrata	29%	93%
P92182	Lumbricus terrestris	29%	93%
P93371	Nicotiana tabacum	31%	100%
P93372	Nicotiana tabacum	31%	100%
P93373	Nicotiana tabacum	33%	100%
P93374	Nicotiana tabacum	31%	100%
P93375	Nicotiana tabacum	32%	100%
P93376	Nicotiana tabacum	32%	100%
P93584	Solanum tuberosum	32%	100%
P93585	Solanum tuberosum	31%	100%
P93586	Solanum tuberosum	32%	100%
P93587	Solanum tuberosum	31%	100%
P93738	Arabidopsis thaliana	28%	95%
Q00214	Styela plicata	30%	92%
Q00215	Styela plicata	28%	93%
Q03341	Echinococcus granulosus	29%	93%
Q03342	Echinococcus granulosus	30%	100%
Q05214	Nicotiana tabacum	29%	92%
Q07903	Strongylocentrotus purpuratus	29%	93%
Q09443	Caenorhabditis elegans	26%	83%
Q09849	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	21%	82%
Q0PGG4	Bos mutus grunniens	29%	93%
Q10AZ4	Oryza sativa subsp. japonica	28%	92%
Q10DV7	Oryza sativa subsp. japonica	28%	92%
Q25010	Helicoverpa armigera	29%	93%
Q25472	Molgula oculata	29%	92%
Q26065	Placopecten magellanicus	29%	93%
Q2T9W4	Bos taurus	27%	84%
Q2TA43	Bos taurus	27%	92%
Q2U7A3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	29%	93%
Q32KZ2	Bos taurus	28%	79%
Q32L91	Bos taurus	27%	83%
Q39758	Fucus vesiculosus	29%	93%
Q3ZBD2	Bos taurus	26%	83%
Q3ZC07	Bos taurus	29%	92%
Q4L0Y2	Spermophilus citellus	29%	93%
Q4Q187	Leishmania major	24%	100%
Q4QD95	Leishmania major	26%	100%
Q4QF44	Leishmania major	77%	100%
Q4QF49	Leishmania major	25%	100%
Q4QR76	Rattus norvegicus	27%	83%
Q4R317	Macaca fascicularis	30%	92%
Q4R333	Macaca fascicularis	23%	81%
Q4R561	Macaca fascicularis	29%	93%
Q4R6J9	Macaca fascicularis	28%	93%
Q4R6Q3	Macaca fascicularis	28%	80%
Q4R821	Macaca fascicularis	29%	93%
Q4V7C7	Rattus norvegicus	35%	83%
Q4W9M3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	74%
Q4YU79	Plasmodium berghei (strain Anka)	29%	93%
Q4Z1L3	Plasmodium berghei (strain Anka)	29%	93%
Q54GX7	Dictyostelium discoideum	29%	93%
Q54HE7	Dictyostelium discoideum	27%	99%
Q54HE9	Dictyostelium discoideum	26%	94%
Q54HF0	Dictyostelium discoideum	26%	90%
Q54HF1	Dictyostelium discoideum	26%	92%
Q54I79	Dictyostelium discoideum	25%	91%
Q54L54	Dictyostelium discoideum	26%	90%
Q553U6	Dictyostelium discoideum	30%	93%
Q554S6	Dictyostelium discoideum	26%	93%
Q55CU2	Dictyostelium discoideum	26%	93%
Q55EU6	Dictyostelium discoideum	29%	97%
Q562R1	Homo sapiens	29%	93%
Q56A35	Danio rerio	26%	88%
Q5BL41	Xenopus tropicalis	26%	88%
Q5E9B5	Bos taurus	29%	93%
Q5JAK2	Pelophylax lessonae	29%	93%
Q5JWF8	Homo sapiens	27%	100%
Q5M7U6	Rattus norvegicus	26%	88%
Q5NBI2	Oryza sativa subsp. japonica	22%	81%
Q5R1X3	Pan troglodytes	29%	93%
Q5R4K0	Pongo abelii	25%	88%
Q5R6G0	Pongo abelii	29%	93%
Q5R8R1	Pongo abelii	35%	83%
Q5R9Q5	Pongo abelii	29%	92%
Q5XIK1	Rattus norvegicus	28%	93%
Q5ZMQ2	Gallus gallus	29%	93%
Q61JZ2	Caenorhabditis briggsae	28%	89%
Q61WW9	Caenorhabditis briggsae	35%	82%
Q641P0	Mus musculus	35%	83%
Q641W9	Rattus norvegicus	28%	79%
Q6AY16	Rattus norvegicus	26%	85%
Q6BML9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	21%	85%
Q6C061	Yarrowia lipolytica (strain CLIB 122 / E 150)	20%	81%
Q6C982	Yarrowia lipolytica (strain CLIB 122 / E 150)	22%	90%
Q6CJF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	21%	84%
Q6K908	Oryza sativa subsp. japonica	36%	81%
Q6NVA9	Xenopus tropicalis	29%	93%
Q6P378	Xenopus tropicalis	29%	93%
Q6P640	Xenopus tropicalis	29%	92%
Q6P8G3	Xenopus tropicalis	29%	92%
Q6QAQ1	Sus scrofa	29%	93%
Q6TCF2	Gaeumannomyces avenae	29%	93%
Q6Z256	Oryza sativa subsp. japonica	27%	89%
Q6ZJW9	Oryza sativa subsp. japonica	24%	79%
Q711N9	Mesocricetus auratus	29%	93%
Q71FK5	Cavia porcellus	29%	93%
Q74ZV8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	22%	85%
Q754G5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	22%	73%
Q75D00	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	29%	93%
Q76N69	Chlorocebus aethiops	29%	93%
Q7RME1	Plasmodium yoelii yoelii	29%	93%
Q7RPB4	Plasmodium yoelii yoelii	29%	93%
Q7SXW6	Danio rerio	26%	88%
Q7ZTP2	Xenopus laevis	26%	88%
Q7ZVF9	Danio rerio	29%	93%
Q7ZVI7	Danio rerio	29%	93%
Q7ZXV3	Xenopus laevis	26%	88%
Q801P7	Xenopus laevis	34%	83%
Q84M92	Arabidopsis thaliana	23%	79%
Q8BFZ3	Mus musculus	29%	93%
Q8BXF8	Mus musculus	28%	94%
Q8CG27	Mus musculus	27%	84%
Q8I4X0	Plasmodium falciparum (isolate 3D7)	29%	93%
Q8ILW9	Plasmodium falciparum (isolate 3D7)	28%	93%
Q8JJB8	Triakis scyllium	29%	93%
Q8L4Y5	Arabidopsis thaliana	24%	96%
Q8LGE3	Arabidopsis thaliana	25%	83%
Q8R5C5	Mus musculus	29%	93%
Q8RYC2	Arabidopsis thaliana	30%	92%
Q8SWN8	Encephalitozoon cuniculi (strain GB-M1)	29%	93%
Q8TC94	Homo sapiens	27%	84%
Q8TDG2	Homo sapiens	30%	93%
Q8TDY3	Homo sapiens	28%	92%
Q8X119	Exophiala dermatitidis	30%	93%
Q90WD0	Gallus gallus	35%	83%
Q90X97	Atractaspis microlepidota microlepidota	29%	92%
Q91ZK5	Sigmodon hispidus	29%	93%
Q92192	Calanus finmarchicus	31%	100%
Q92193	Crassostrea virginica	32%	100%
Q93129	Branchiostoma belcheri	29%	93%
Q93130	Branchiostoma belcheri	28%	92%
Q93131	Branchiostoma floridae	29%	93%
Q93132	Branchiostoma floridae	27%	92%
Q95JK8	Macaca fascicularis	27%	84%
Q96292	Arabidopsis thaliana	28%	92%
Q96293	Arabidopsis thaliana	28%	92%
Q96481	Solanum lycopersicum	32%	100%
Q96482	Solanum lycopersicum	32%	100%
Q96483	Solanum lycopersicum	33%	100%
Q96484	Solanum lycopersicum	31%	100%
Q964D9	Planorbella trivolvis	29%	93%
Q964E0	Biomphalaria tenagophila	29%	93%
Q964E1	Biomphalaria obstructa	29%	93%
Q964E2	Biomphalaria pfeifferi	29%	93%
Q964E3	Biomphalaria alexandrina	29%	93%
Q98972	Oryzias latipes	28%	92%
Q99023	Hypocrea jecorina	29%	93%
Q99JY9	Mus musculus	35%	83%
Q99MR0	Mus musculus	23%	82%
Q9BYD9	Homo sapiens	30%	94%
Q9BYX7	Homo sapiens	28%	93%
Q9D9J3	Mus musculus	27%	93%
Q9D9L5	Mus musculus	29%	92%
Q9DEE9	Gallus gallus	22%	88%
Q9H568	Homo sapiens	25%	95%
Q9LSD6	Arabidopsis thaliana	26%	89%
Q9N4I0	Caenorhabditis elegans	34%	82%
Q9NJV4	Naegleria pringsheimi	28%	93%
Q9NZ32	Homo sapiens	25%	83%
Q9P1U1	Homo sapiens	34%	83%
Q9P4D1	Komagataella phaffii (strain GS115 / ATCC 20864)	28%	93%
Q9P7X7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	23%	80%
Q9QY83	Mus musculus	27%	83%
Q9QY84	Mus musculus	28%	79%
Q9QZB7	Mus musculus	24%	83%
Q9SAF1	Arabidopsis thaliana	38%	81%
Q9U1E8	Leishmania major	29%	100%
Q9URS0	Penicillium chrysogenum	28%	93%
Q9UUJ1	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	89%
Q9UVF3	Yarrowia lipolytica (strain CLIB 122 / E 150)	29%	93%
Q9UVW9	Acremonium chrysogenum	29%	93%
Q9UVX4	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	30%	93%
Q9UVZ8	Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841)	29%	93%
Q9Y614	Homo sapiens	28%	84%
Q9Y615	Homo sapiens	28%	80%
Q9Y701	Suillus bovinus	29%	93%
Q9Y702	Schizophyllum commune	29%	93%
Q9Y707	Suillus bovinus	29%	93%
Q9Y896	Schizophyllum commune	28%	93%
Q9Z2N8	Mus musculus	23%	81%
V5AVP6	Trypanosoma cruzi	23%	100%
V5AW65	Trypanosoma cruzi	33%	89%
V5AZ19	Trypanosoma cruzi	24%	86%
V5BDL0	Trypanosoma cruzi	29%	93%
V5BPT0	Trypanosoma cruzi	40%	84%
V5BWS6	Trypanosoma cruzi	28%	91%
V5C0Q2	Trypanosoma cruzi	29%	89%