Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H899_LEIBR

TriTrypDb:

LbrM.15.1310 , LBRM2903_150020300

Length:

331

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H899

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H899

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	220	224	PF00656	0.461
CLV_C14_Caspase3-7	270	274	PF00656	0.607
CLV_NRD_NRD_1	178	180	PF00675	0.718
CLV_NRD_NRD_1	55	57	PF00675	0.461
CLV_PCSK_KEX2_1	178	180	PF00082	0.710
CLV_PCSK_SKI1_1	207	211	PF00082	0.488
CLV_PCSK_SKI1_1	60	64	PF00082	0.606
DOC_CKS1_1	17	22	PF01111	0.713
DOC_PP1_SILK_1	163	168	PF00149	0.548
DOC_PP2B_LxvP_1	15	18	PF13499	0.558
DOC_PP4_FxxP_1	189	192	PF00568	0.566
DOC_USP7_MATH_1	132	136	PF00917	0.625
DOC_USP7_MATH_1	90	94	PF00917	0.580
DOC_WW_Pin1_4	10	15	PF00397	0.644
DOC_WW_Pin1_4	113	118	PF00397	0.754
DOC_WW_Pin1_4	121	126	PF00397	0.780
DOC_WW_Pin1_4	16	21	PF00397	0.484
DOC_WW_Pin1_4	194	199	PF00397	0.808
DOC_WW_Pin1_4	236	241	PF00397	0.506
DOC_WW_Pin1_4	3	8	PF00397	0.802
LIG_14-3-3_CanoR_1	141	151	PF00244	0.485
LIG_14-3-3_CanoR_1	194	198	PF00244	0.668
LIG_14-3-3_CanoR_1	200	205	PF00244	0.632
LIG_14-3-3_CanoR_1	207	217	PF00244	0.590
LIG_14-3-3_CanoR_1	54	64	PF00244	0.411
LIG_BIR_III_4	127	131	PF00653	0.545
LIG_FHA_1	17	23	PF00498	0.812
LIG_FHA_1	209	215	PF00498	0.631
LIG_FHA_1	233	239	PF00498	0.509
LIG_FHA_1	31	37	PF00498	0.466
LIG_FHA_2	122	128	PF00498	0.676
LIG_FHA_2	178	184	PF00498	0.554
LIG_FHA_2	323	329	PF00498	0.527
LIG_FHA_2	56	62	PF00498	0.561
LIG_LIR_Apic_2	186	192	PF02991	0.565
LIG_MYND_1	121	125	PF01753	0.712
LIG_RPA_C_Fungi	216	228	PF08784	0.576
LIG_SH2_STAP1	301	305	PF00017	0.667
LIG_SH2_STAT5	301	304	PF00017	0.513
LIG_SH3_3	11	17	PF00018	0.718
LIG_SH3_3	155	161	PF00018	0.652
LIG_SH3_3	199	205	PF00018	0.768
LIG_SH3_3	25	31	PF00018	0.709
LIG_SUMO_SIM_par_1	234	239	PF11976	0.490
LIG_TRAF2_1	281	284	PF00917	0.829
LIG_UBA3_1	52	57	PF00899	0.398
LIG_WW_2	20	23	PF00397	0.717
LIG_WW_3	197	201	PF00397	0.727
LIG_WW_3	204	208	PF00397	0.742
MOD_CDC14_SPxK_1	197	200	PF00782	0.561
MOD_CDC14_SPxK_1	6	9	PF00782	0.566
MOD_CDK_SPxK_1	194	200	PF00069	0.562
MOD_CDK_SPxK_1	3	9	PF00069	0.566
MOD_CK1_1	168	174	PF00069	0.712
MOD_CK1_1	177	183	PF00069	0.739
MOD_CK1_1	208	214	PF00069	0.570
MOD_CK1_1	250	256	PF00069	0.651
MOD_CK1_1	296	302	PF00069	0.624
MOD_CK1_1	3	9	PF00069	0.749
MOD_CK1_1	309	315	PF00069	0.599
MOD_CK2_1	142	148	PF00069	0.629
MOD_CK2_1	177	183	PF00069	0.553
MOD_CK2_1	322	328	PF00069	0.527
MOD_CK2_1	55	61	PF00069	0.561
MOD_Cter_Amidation	172	175	PF01082	0.590
MOD_DYRK1A_RPxSP_1	194	198	PF00069	0.560
MOD_GlcNHglycan	133	137	PF01048	0.561
MOD_GlcNHglycan	170	173	PF01048	0.644
MOD_GlcNHglycan	2	5	PF01048	0.818
MOD_GlcNHglycan	207	210	PF01048	0.692
MOD_GlcNHglycan	243	246	PF01048	0.773
MOD_GlcNHglycan	316	319	PF01048	0.756
MOD_GSK3_1	115	122	PF00069	0.788
MOD_GSK3_1	161	168	PF00069	0.681
MOD_GSK3_1	194	201	PF00069	0.672
MOD_GSK3_1	232	239	PF00069	0.645
MOD_GSK3_1	306	313	PF00069	0.728
MOD_GSK3_1	324	331	PF00069	0.498
MOD_NEK2_1	187	192	PF00069	0.566
MOD_NEK2_1	217	222	PF00069	0.627
MOD_NEK2_1	293	298	PF00069	0.583
MOD_NEK2_1	55	60	PF00069	0.489
MOD_PKA_1	174	180	PF00069	0.553
MOD_PKA_2	177	183	PF00069	0.757
MOD_PKA_2	193	199	PF00069	0.714
MOD_PKA_2	307	313	PF00069	0.571
MOD_PKA_2	55	61	PF00069	0.480
MOD_Plk_1	90	96	PF00069	0.509
MOD_Plk_4	161	167	PF00069	0.542
MOD_ProDKin_1	10	16	PF00069	0.639
MOD_ProDKin_1	113	119	PF00069	0.755
MOD_ProDKin_1	121	127	PF00069	0.780
MOD_ProDKin_1	194	200	PF00069	0.809
MOD_ProDKin_1	236	242	PF00069	0.508
MOD_ProDKin_1	3	9	PF00069	0.804
TRG_DiLeu_BaLyEn_6	48	53	PF01217	0.633
TRG_ER_diArg_1	53	56	PF00400	0.556
TRG_NES_CRM1_1	137	150	PF08389	0.479
TRG_NLS_MonoExtC_3	173	178	PF00514	0.639
TRG_NLS_MonoExtN_4	174	179	PF00514	0.616

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEC2	Leptomonas seymouri	37%	96%
A0A3Q8IDH2	Leishmania donovani	62%	100%
A4HWM1	Leishmania infantum	61%	100%
E9AQC8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	62%	100%
Q4QF47	Leishmania major	58%	99%