Cytochrome b5 heme-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

cytochrome b5-like Heme/Steroid binding domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4H7Y9_LEIBR

TriTrypDb:

LbrM.15.0190 , LBRM2903_150007100

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	13
GO:0110165	cellular anatomical entity	1	13
GO:0005741	mitochondrial outer membrane	5	1
GO:0012505	endomembrane system	2	2
GO:0019867	outer membrane	3	1
GO:0031090	organelle membrane	3	1
GO:0031966	mitochondrial membrane	4	1
GO:0031968	organelle outer membrane	4	1
GO:0098588	bounding membrane of organelle	4	1
GO:0005783	endoplasmic reticulum	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

A4H7Y9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7Y9


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	156	158	PF00082	0.297
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.297
DOC_MAPK_gen_1	66	75	PF00069	0.472
DOC_MAPK_MEF2A_6	14	23	PF00069	0.374
DOC_MAPK_NFAT4_5	14	22	PF00069	0.183
DOC_PP1_RVXF_1	30	36	PF00149	0.313
DOC_PP4_FxxP_1	42	45	PF00568	0.482
DOC_USP7_UBL2_3	152	156	PF12436	0.558
DOC_WW_Pin1_4	120	125	PF00397	0.492
LIG_14-3-3_CanoR_1	157	162	PF00244	0.607
LIG_14-3-3_CanoR_1	4	12	PF00244	0.265
LIG_14-3-3_CanoR_1	53	58	PF00244	0.490
LIG_BIR_II_1	1	5	PF00653	0.488
LIG_FHA_1	7	13	PF00498	0.325
LIG_FHA_2	127	133	PF00498	0.410
LIG_FHA_2	54	60	PF00498	0.427
LIG_LIR_Apic_2	83	89	PF02991	0.455
LIG_LIR_Gen_1	118	127	PF02991	0.414
LIG_LIR_Gen_1	90	97	PF02991	0.479
LIG_LIR_Nem_3	118	122	PF02991	0.405
LIG_LIR_Nem_3	139	144	PF02991	0.452
LIG_LIR_Nem_3	90	96	PF02991	0.470
LIG_LYPXL_yS_3	141	144	PF13949	0.470
LIG_NRBOX	14	20	PF00104	0.150
LIG_Pex14_2	22	26	PF04695	0.263
LIG_Pex3_1	15	26	PF04882	0.150
LIG_SH2_STAP1	93	97	PF00017	0.530
LIG_SH2_STAT5	55	58	PF00017	0.463
LIG_SH3_3	86	92	PF00018	0.446
LIG_SUMO_SIM_anti_2	13	19	PF11976	0.144
LIG_TRAF2_1	56	59	PF00917	0.417
MOD_CK2_1	126	132	PF00069	0.328
MOD_CK2_1	5	11	PF00069	0.317
MOD_CK2_1	53	59	PF00069	0.280
MOD_Cter_Amidation	64	67	PF01082	0.350
MOD_GlcNHglycan	1	4	PF01048	0.639
MOD_GlcNHglycan	93	96	PF01048	0.446
MOD_GSK3_1	6	13	PF00069	0.328
MOD_N-GLC_1	4	9	PF02516	0.352
MOD_N-GLC_1	80	85	PF02516	0.344
MOD_PIKK_1	58	64	PF00454	0.244
MOD_Plk_1	117	123	PF00069	0.237
MOD_Plk_1	58	64	PF00069	0.150
MOD_Plk_1	80	86	PF00069	0.383
MOD_Plk_4	13	19	PF00069	0.323
MOD_ProDKin_1	120	126	PF00069	0.358
TRG_ENDOCYTIC_2	141	144	PF00928	0.282
TRG_ENDOCYTIC_2	93	96	PF00928	0.302
TRG_ER_diArg_1	35	38	PF00400	0.340


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C7	Leptomonas seymouri	37%	100%
A0A0N1I2M9	Leptomonas seymouri	69%	100%
A0A0S4IM89	Bodo saltans	39%	100%
A0A0S4IWT4	Bodo saltans	29%	95%
A0A0S4KHZ8	Bodo saltans	57%	100%
A0A1X0NM31	Trypanosomatidae	35%	100%
A0A1X0NTL9	Trypanosomatidae	60%	100%
A0A3Q8IGX1	Leishmania donovani	40%	100%
A0A3R7L838	Trypanosoma rangeli	36%	100%
A0A3R7RC54	Trypanosoma rangeli	35%	91%
A0A3S7WTB2	Leishmania donovani	79%	100%
A0A3S7X865	Leishmania donovani	40%	92%
A0A422NSD0	Trypanosoma rangeli	59%	100%
A4HB24	Leishmania braziliensis	40%	92%
A4HQJ0	Leishmania braziliensis	37%	100%
A4HWB7	Leishmania infantum	79%	100%
A4IA81	Leishmania infantum	40%	92%
C9ZM28	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZNV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9AHZ9	Leishmania infantum	40%	100%
E9AQ17	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
E9AUA3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B594	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	92%
O13995	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	98%
Q2HIW2	Arabidopsis thaliana	29%	67%
Q4Q2N9	Leishmania major	40%	92%
Q4QFG4	Leishmania major	79%	100%
Q5XIU9	Rattus norvegicus	30%	75%
Q7YZW5	Caenorhabditis elegans	33%	89%
Q80UU9	Mus musculus	30%	75%
V5DM24	Trypanosoma cruzi	32%	91%