Protein UL34

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Protein UL34

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H7V8_LEIBR

TriTrypDb:

LbrM.14.1570 , LBRM2903_140020600

Length:

416

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7V8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7V8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	238	242	PF00656	0.320
CLV_NRD_NRD_1	112	114	PF00675	0.325
CLV_NRD_NRD_1	208	210	PF00675	0.559
CLV_NRD_NRD_1	270	272	PF00675	0.453
CLV_NRD_NRD_1	70	72	PF00675	0.551
CLV_NRD_NRD_1	77	79	PF00675	0.545
CLV_NRD_NRD_1	91	93	PF00675	0.453
CLV_PCSK_KEX2_1	112	114	PF00082	0.326
CLV_PCSK_KEX2_1	208	210	PF00082	0.436
CLV_PCSK_KEX2_1	270	272	PF00082	0.395
CLV_PCSK_KEX2_1	70	72	PF00082	0.551
CLV_PCSK_KEX2_1	77	79	PF00082	0.543
CLV_PCSK_KEX2_1	91	93	PF00082	0.453
CLV_PCSK_PC7_1	266	272	PF00082	0.369
CLV_PCSK_SKI1_1	187	191	PF00082	0.378
CLV_PCSK_SKI1_1	202	206	PF00082	0.367
CLV_PCSK_SKI1_1	228	232	PF00082	0.526
CLV_PCSK_SKI1_1	349	353	PF00082	0.538
CLV_PCSK_SKI1_1	5	9	PF00082	0.485
CLV_Separin_Metazoa	109	113	PF03568	0.353
CLV_Separin_Metazoa	250	254	PF03568	0.335
CLV_Separin_Metazoa	308	312	PF03568	0.523
DEG_Nend_UBRbox_4	1	3	PF02207	0.481
DEG_SPOP_SBC_1	85	89	PF00917	0.513
DOC_ANK_TNKS_1	43	50	PF00023	0.519
DOC_CKS1_1	61	66	PF01111	0.528
DOC_CYCLIN_RxL_1	184	194	PF00134	0.354
DOC_CYCLIN_RxL_1	199	207	PF00134	0.399
DOC_CYCLIN_RxL_1	53	63	PF00134	0.519
DOC_CYCLIN_yCln2_LP_2	151	157	PF00134	0.332
DOC_CYCLIN_yCln2_LP_2	189	195	PF00134	0.417
DOC_CYCLIN_yCln2_LP_2	45	48	PF00134	0.522
DOC_MAPK_gen_1	156	164	PF00069	0.489
DOC_MAPK_RevD_3	258	271	PF00069	0.403
DOC_MIT_MIM_1	181	189	PF04212	0.276
DOC_PP1_RVXF_1	279	286	PF00149	0.398
DOC_PP2B_LxvP_1	45	48	PF13499	0.524
DOC_PP4_FxxP_1	258	261	PF00568	0.453
DOC_PP4_FxxP_1	381	384	PF00568	0.593
DOC_USP7_MATH_1	275	279	PF00917	0.384
DOC_USP7_MATH_1	405	409	PF00917	0.480
DOC_USP7_MATH_1	48	52	PF00917	0.517
DOC_WW_Pin1_4	169	174	PF00397	0.382
DOC_WW_Pin1_4	354	359	PF00397	0.482
DOC_WW_Pin1_4	376	381	PF00397	0.586
DOC_WW_Pin1_4	403	408	PF00397	0.489
DOC_WW_Pin1_4	60	65	PF00397	0.578
LIG_14-3-3_CanoR_1	185	190	PF00244	0.342
LIG_14-3-3_CanoR_1	270	276	PF00244	0.510
LIG_14-3-3_CanoR_1	317	324	PF00244	0.483
LIG_14-3-3_CanoR_1	369	373	PF00244	0.555
LIG_14-3-3_CanoR_1	382	390	PF00244	0.554
LIG_14-3-3_CanoR_1	86	94	PF00244	0.480
LIG_14-3-3_CterR_2	413	416	PF00244	0.504
LIG_Actin_WH2_2	261	279	PF00022	0.320
LIG_BRCT_BRCA1_1	139	143	PF00533	0.306
LIG_FHA_1	15	21	PF00498	0.501
LIG_FHA_1	205	211	PF00498	0.392
LIG_FHA_1	262	268	PF00498	0.354
LIG_FHA_1	335	341	PF00498	0.486
LIG_FHA_1	40	46	PF00498	0.619
LIG_FHA_1	70	76	PF00498	0.611
LIG_FHA_2	17	23	PF00498	0.517
LIG_FHA_2	186	192	PF00498	0.404
LIG_FHA_2	320	326	PF00498	0.753
LIG_Integrin_RGD_1	168	170	PF01839	0.326
LIG_LIR_Apic_2	379	384	PF02991	0.588
LIG_LIR_Gen_1	124	133	PF02991	0.349
LIG_LIR_Gen_1	140	151	PF02991	0.349
LIG_LIR_Gen_1	161	170	PF02991	0.374
LIG_LIR_Gen_1	211	220	PF02991	0.592
LIG_LIR_Gen_1	241	252	PF02991	0.301
LIG_LIR_Gen_1	398	407	PF02991	0.490
LIG_LIR_Gen_1	96	104	PF02991	0.373
LIG_LIR_Nem_3	124	129	PF02991	0.365
LIG_LIR_Nem_3	161	167	PF02991	0.367
LIG_LIR_Nem_3	188	193	PF02991	0.475
LIG_LIR_Nem_3	211	215	PF02991	0.541
LIG_LIR_Nem_3	241	247	PF02991	0.454
LIG_LIR_Nem_3	264	268	PF02991	0.404
LIG_LIR_Nem_3	398	403	PF02991	0.492
LIG_LIR_Nem_3	96	102	PF02991	0.403
LIG_NRBOX	200	206	PF00104	0.401
LIG_NRBOX	226	232	PF00104	0.430
LIG_SH2_CRK	212	216	PF00017	0.434
LIG_SH2_CRK	400	404	PF00017	0.469
LIG_SH2_STAT5	212	215	PF00017	0.609
LIG_SH3_2	66	71	PF14604	0.523
LIG_SH3_3	151	157	PF00018	0.332
LIG_SH3_3	257	263	PF00018	0.452
LIG_SH3_3	303	309	PF00018	0.561
LIG_SH3_3	387	393	PF00018	0.594
LIG_SH3_3	401	407	PF00018	0.587
LIG_SH3_3	63	69	PF00018	0.613
LIG_SUMO_SIM_anti_2	178	184	PF11976	0.301
LIG_SUMO_SIM_anti_2	191	197	PF11976	0.416
LIG_SUMO_SIM_par_1	178	184	PF11976	0.301
LIG_TYR_ITIM	210	215	PF00017	0.430
LIG_WRC_WIRS_1	262	267	PF05994	0.361
LIG_WW_3	53	57	PF00397	0.498
MOD_CDC14_SPxK_1	379	382	PF00782	0.526
MOD_CDK_SPxK_1	376	382	PF00069	0.518
MOD_CK1_1	131	137	PF00069	0.435
MOD_CK1_1	229	235	PF00069	0.365
MOD_CK1_1	316	322	PF00069	0.658
MOD_CK1_1	341	347	PF00069	0.448
MOD_CK1_1	383	389	PF00069	0.563
MOD_CK1_1	84	90	PF00069	0.529
MOD_CK2_1	103	109	PF00069	0.427
MOD_CK2_1	175	181	PF00069	0.368
MOD_CK2_1	185	191	PF00069	0.388
MOD_CK2_1	30	36	PF00069	0.517
MOD_GlcNHglycan	26	29	PF01048	0.545
MOD_GlcNHglycan	271	274	PF01048	0.466
MOD_GlcNHglycan	32	35	PF01048	0.636
MOD_GlcNHglycan	385	388	PF01048	0.626
MOD_GSK3_1	137	144	PF00069	0.325
MOD_GSK3_1	24	31	PF00069	0.503
MOD_GSK3_1	334	341	PF00069	0.597
MOD_GSK3_1	368	375	PF00069	0.578
MOD_GSK3_1	376	383	PF00069	0.571
MOD_GSK3_1	403	410	PF00069	0.472
MOD_GSK3_1	80	87	PF00069	0.528
MOD_N-GLC_1	131	136	PF02516	0.345
MOD_N-GLC_1	39	44	PF02516	0.545
MOD_NEK2_1	204	209	PF00069	0.388
MOD_NEK2_1	24	29	PF00069	0.500
MOD_NEK2_1	313	318	PF00069	0.454
MOD_NEK2_1	339	344	PF00069	0.454
MOD_NEK2_1	368	373	PF00069	0.577
MOD_PKA_2	269	275	PF00069	0.418
MOD_PKA_2	316	322	PF00069	0.459
MOD_PKA_2	334	340	PF00069	0.567
MOD_PKA_2	368	374	PF00069	0.554
MOD_PKA_2	69	75	PF00069	0.625
MOD_PKA_2	85	91	PF00069	0.506
MOD_Plk_1	131	137	PF00069	0.399
MOD_Plk_1	141	147	PF00069	0.381
MOD_Plk_1	313	319	PF00069	0.454
MOD_Plk_2-3	299	305	PF00069	0.459
MOD_Plk_4	319	325	PF00069	0.468
MOD_ProDKin_1	169	175	PF00069	0.378
MOD_ProDKin_1	354	360	PF00069	0.483
MOD_ProDKin_1	376	382	PF00069	0.591
MOD_ProDKin_1	403	409	PF00069	0.490
MOD_ProDKin_1	60	66	PF00069	0.573
TRG_AP2beta_CARGO_1	161	171	PF09066	0.384
TRG_DiLeu_BaEn_1	243	248	PF01217	0.294
TRG_DiLeu_BaEn_2	140	146	PF01217	0.385
TRG_DiLeu_BaLyEn_6	263	268	PF01217	0.389
TRG_ENDOCYTIC_2	212	215	PF00928	0.609
TRG_ENDOCYTIC_2	400	403	PF00928	0.494
TRG_ER_diArg_1	111	113	PF00400	0.331
TRG_ER_diArg_1	155	158	PF00400	0.403
TRG_ER_diArg_1	208	210	PF00400	0.441
TRG_ER_diArg_1	269	271	PF00400	0.384
TRG_ER_diArg_1	69	71	PF00400	0.543
TRG_ER_diArg_1	91	93	PF00400	0.475
TRG_Pf-PMV_PEXEL_1	187	191	PF00026	0.555
TRG_Pf-PMV_PEXEL_1	202	206	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	281	286	PF00026	0.482
TRG_Pf-PMV_PEXEL_1	92	96	PF00026	0.417

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q5	Leptomonas seymouri	42%	99%
A0A3Q8I8Y2	Leishmania donovani	69%	100%
A4HW84	Leishmania infantum	69%	100%
E9APY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	100%
Q4QFJ6	Leishmania major	70%	100%