REJ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H7U6_LEIBR

TriTrypDb:

LbrM.14.1430 , LBRM2903_140019000

Length:

152

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 5
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7U6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	13	17	PF00082	0.527
DEG_Nend_UBRbox_2	1	3	PF02207	0.598
DEG_SCF_FBW7_1	59	66	PF00400	0.378
DOC_CKS1_1	141	146	PF01111	0.387
DOC_USP7_MATH_1	28	32	PF00917	0.566
DOC_USP7_MATH_1	37	41	PF00917	0.433
DOC_USP7_MATH_1	63	67	PF00917	0.518
DOC_WW_Pin1_4	140	145	PF00397	0.465
DOC_WW_Pin1_4	24	29	PF00397	0.432
DOC_WW_Pin1_4	59	64	PF00397	0.666
LIG_14-3-3_CanoR_1	58	63	PF00244	0.451
LIG_BRCT_BRCA1_1	87	91	PF00533	0.423
LIG_FHA_1	141	147	PF00498	0.379
LIG_FHA_1	44	50	PF00498	0.408
LIG_FHA_1	51	57	PF00498	0.373
LIG_FHA_1	60	66	PF00498	0.408
LIG_FHA_2	77	83	PF00498	0.331
LIG_LIR_Gen_1	6	15	PF02991	0.514
LIG_LIR_Gen_1	66	72	PF02991	0.414
LIG_LIR_Nem_3	111	116	PF02991	0.453
LIG_LIR_Nem_3	145	150	PF02991	0.582
LIG_LIR_Nem_3	6	11	PF02991	0.540
LIG_LIR_Nem_3	66	70	PF02991	0.404
LIG_SH2_CRK	67	71	PF00017	0.438
LIG_SH2_NCK_1	34	38	PF00017	0.423
LIG_SH2_NCK_1	67	71	PF00017	0.408
LIG_SH2_STAP1	34	38	PF00017	0.423
LIG_SH2_STAP1	45	49	PF00017	0.337
LIG_SH2_STAT3	119	122	PF00017	0.386
LIG_SH2_STAT5	119	122	PF00017	0.381
LIG_SH2_STAT5	45	48	PF00017	0.430
LIG_SH3_3	138	144	PF00018	0.465
LIG_SH3_3	53	59	PF00018	0.444
LIG_SUMO_SIM_anti_2	46	53	PF11976	0.399
LIG_SUMO_SIM_anti_2	96	102	PF11976	0.393
LIG_SUMO_SIM_par_1	52	57	PF11976	0.395
LIG_TYR_ITIM	116	121	PF00017	0.340
LIG_TYR_ITIM	65	70	PF00017	0.430
MOD_CK1_1	123	129	PF00069	0.375
MOD_CK1_1	145	151	PF00069	0.397
MOD_CK1_1	3	9	PF00069	0.483
MOD_CK2_1	49	55	PF00069	0.376
MOD_DYRK1A_RPxSP_1	140	144	PF00069	0.396
MOD_GlcNHglycan	122	125	PF01048	0.420
MOD_GlcNHglycan	127	130	PF01048	0.454
MOD_GlcNHglycan	2	5	PF01048	0.706
MOD_GlcNHglycan	39	42	PF01048	0.350
MOD_GSK3_1	104	111	PF00069	0.547
MOD_GSK3_1	13	20	PF00069	0.640
MOD_GSK3_1	24	31	PF00069	0.495
MOD_GSK3_1	39	46	PF00069	0.387
MOD_GSK3_1	50	57	PF00069	0.354
MOD_GSK3_1	59	66	PF00069	0.342
MOD_GSK3_1	85	92	PF00069	0.374
MOD_N-GLC_1	133	138	PF02516	0.512
MOD_NEK2_1	54	59	PF00069	0.340
MOD_NEK2_1	89	94	PF00069	0.509
MOD_OFUCOSY	74	80	PF10250	0.322
MOD_PIKK_1	29	35	PF00454	0.363
MOD_PKA_2	57	63	PF00069	0.410
MOD_Plk_4	142	148	PF00069	0.494
MOD_Plk_4	45	51	PF00069	0.475
MOD_Plk_4	65	71	PF00069	0.369
MOD_ProDKin_1	140	146	PF00069	0.458
MOD_ProDKin_1	24	30	PF00069	0.437
MOD_ProDKin_1	59	65	PF00069	0.656
MOD_SUMO_rev_2	77	85	PF00179	0.329
TRG_ENDOCYTIC_2	118	121	PF00928	0.358
TRG_ENDOCYTIC_2	12	15	PF00928	0.658
TRG_ENDOCYTIC_2	67	70	PF00928	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA15	Leptomonas seymouri	44%	80%
A0A3S5H6S9	Leishmania donovani	68%	100%
A4H7U5	Leishmania braziliensis	27%	100%
A4HW72	Leishmania infantum	68%	100%
E9APX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	100%
Q4QFK8	Leishmania major	67%	100%