5_nucleotid_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H7U5_LEIBR

TriTrypDb:

LbrM.14.1420 , LBRM2903_140018900

Length:

206

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 3, no: 6
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7U5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7U5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.609
CLV_PCSK_KEX2_1	10	12	PF00082	0.609
CLV_PCSK_SKI1_1	142	146	PF00082	0.412
CLV_PCSK_SKI1_1	164	168	PF00082	0.363
CLV_PCSK_SKI1_1	199	203	PF00082	0.477
DOC_CYCLIN_yCln2_LP_2	95	101	PF00134	0.432
DOC_MAPK_gen_1	10	17	PF00069	0.585
DOC_MAPK_MEF2A_6	10	19	PF00069	0.575
DOC_MAPK_MEF2A_6	45	52	PF00069	0.414
DOC_PP2B_LxvP_1	66	69	PF13499	0.434
DOC_SPAK_OSR1_1	174	178	PF12202	0.277
DOC_USP7_MATH_1	119	123	PF00917	0.367
DOC_USP7_MATH_1	80	84	PF00917	0.606
DOC_WW_Pin1_4	94	99	PF00397	0.416
LIG_14-3-3_CanoR_1	182	186	PF00244	0.355
LIG_14-3-3_CanoR_1	195	199	PF00244	0.459
LIG_14-3-3_CanoR_1	64	69	PF00244	0.439
LIG_APCC_ABBA_1	108	113	PF00400	0.361
LIG_BRCT_BRCA1_1	113	117	PF00533	0.368
LIG_FHA_1	133	139	PF00498	0.565
LIG_FHA_1	14	20	PF00498	0.451
LIG_FHA_1	155	161	PF00498	0.352
LIG_FHA_1	76	82	PF00498	0.428
LIG_FHA_2	38	44	PF00498	0.553
LIG_GBD_Chelix_1	84	92	PF00786	0.330
LIG_LIR_Gen_1	184	193	PF02991	0.370
LIG_LIR_Gen_1	200	206	PF02991	0.410
LIG_LIR_Nem_3	105	111	PF02991	0.426
LIG_LIR_Nem_3	197	201	PF02991	0.435
LIG_LIR_Nem_3	60	66	PF02991	0.495
LIG_LIR_Nem_3	96	102	PF02991	0.433
LIG_PDZ_Class_3	201	206	PF00595	0.491
LIG_Pex14_2	198	202	PF04695	0.458
LIG_SH2_CRK	63	67	PF00017	0.494
LIG_SH2_CRK	99	103	PF00017	0.416
LIG_SH2_STAT5	185	188	PF00017	0.501
LIG_SH2_STAT5	76	79	PF00017	0.439
LIG_SH3_3	113	119	PF00018	0.442
LIG_SUMO_SIM_anti_2	120	125	PF11976	0.289
LIG_SUMO_SIM_par_1	25	30	PF11976	0.462
MOD_CK1_1	3	9	PF00069	0.573
MOD_CK1_1	94	100	PF00069	0.448
MOD_CK2_1	80	86	PF00069	0.437
MOD_GlcNHglycan	126	129	PF01048	0.393
MOD_GlcNHglycan	66	69	PF01048	0.447
MOD_GSK3_1	1	8	PF00069	0.601
MOD_GSK3_1	154	161	PF00069	0.345
MOD_GSK3_1	75	82	PF00069	0.527
MOD_N-GLC_1	130	135	PF02516	0.447
MOD_N-GLC_1	6	11	PF02516	0.602
MOD_NEK2_1	1	6	PF00069	0.529
MOD_NEK2_1	149	154	PF00069	0.480
MOD_NEK2_1	62	67	PF00069	0.545
MOD_NEK2_2	194	199	PF00069	0.465
MOD_PKA_2	181	187	PF00069	0.363
MOD_PKA_2	194	200	PF00069	0.439
MOD_Plk_4	111	117	PF00069	0.471
MOD_Plk_4	119	125	PF00069	0.331
MOD_Plk_4	149	155	PF00069	0.419
MOD_Plk_4	181	187	PF00069	0.475
MOD_Plk_4	80	86	PF00069	0.368
MOD_ProDKin_1	94	100	PF00069	0.409
TRG_DiLeu_BaEn_1	105	110	PF01217	0.417
TRG_ENDOCYTIC_2	185	188	PF00928	0.487
TRG_ENDOCYTIC_2	63	66	PF00928	0.521
TRG_ENDOCYTIC_2	99	102	PF00928	0.416
TRG_ER_diArg_1	10	12	PF00400	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HSZ7	Leptomonas seymouri	40%	100%
A0A3S5H6S9	Leishmania donovani	27%	100%
A0A3S7WT67	Leishmania donovani	71%	100%
A4H7U6	Leishmania braziliensis	27%	100%
A4HW71	Leishmania infantum	71%	100%
A4HW72	Leishmania infantum	27%	100%
E9APX2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	100%
Q4QFK9	Leishmania major	71%	100%