LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4H7U3_LEIBR
TriTrypDb:
LbrM.14.1400 , LBRM2903_140018700 *
Length:
569

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7U3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7U3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 106 110 PF00656 0.573
CLV_C14_Caspase3-7 245 249 PF00656 0.678
CLV_NRD_NRD_1 51 53 PF00675 0.597
CLV_NRD_NRD_1 567 569 PF00675 0.613
CLV_PCSK_KEX2_1 567 569 PF00082 0.613
CLV_PCSK_SKI1_1 391 395 PF00082 0.665
CLV_PCSK_SKI1_1 523 527 PF00082 0.572
DEG_Nend_UBRbox_1 1 4 PF02207 0.669
DEG_ODPH_VHL_1 185 196 PF01847 0.517
DEG_SPOP_SBC_1 111 115 PF00917 0.584
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PAA7 Leptomonas seymouri 25% 98%
A0A3S7WTC0 Leishmania donovani 63% 100%
A4HW69 Leishmania infantum 63% 100%
E9APX0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 63% 100%
Q4QFL1 Leishmania major 63% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS