Sulfatase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H7S5_LEIBR

TriTrypDb:

LbrM.14.1220 , LBRM2903_200024700

Length:

356

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

A4H7S5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7S5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.324
CLV_NRD_NRD_1	187	189	PF00675	0.685
CLV_NRD_NRD_1	197	199	PF00675	0.608
CLV_NRD_NRD_1	270	272	PF00675	0.525
CLV_NRD_NRD_1	36	38	PF00675	0.406
CLV_NRD_NRD_1	59	61	PF00675	0.624
CLV_NRD_NRD_1	85	87	PF00675	0.447
CLV_PCSK_KEX2_1	149	151	PF00082	0.463
CLV_PCSK_KEX2_1	270	272	PF00082	0.576
CLV_PCSK_KEX2_1	36	38	PF00082	0.406

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAP6	Leptomonas seymouri	64%	100%
A0A0S4IM03	Bodo saltans	30%	97%
A0A1X0PAG1	Trypanosomatidae	36%	99%
A0A3S7X7R9	Leishmania donovani	82%	100%
A0A422N0E3	Trypanosoma rangeli	37%	100%
A4I9W1	Leishmania infantum	82%	100%
C9ZMS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
E9B4X4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q353	Leishmania major	81%	100%

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