LeishMANIAdb
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Putative dynein heavy chain

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative dynein heavy chain
Gene product:
dynein heavy chain, putative
Species:
Leishmania braziliensis
UniProt:
A4H7R0_LEIBR
TriTrypDb:
LbrM.14.1050 , LBRM2903_140016200 *
Length:
4267

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 6
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 48
NetGPI no yes: 0, no: 48
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 31
GO:0005858 axonemal dynein complex 4 14
GO:0005874 microtubule 6 47
GO:0005875 microtubule associated complex 2 49
GO:0005929 cilium 4 1
GO:0005930 axoneme 2 5
GO:0030286 dynein complex 3 49
GO:0030990 intraciliary transport particle 2 1
GO:0032991 protein-containing complex 1 49
GO:0042995 cell projection 2 1
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Expansion

Sequence features

A4H7R0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0001539 cilium or flagellum-dependent cell motility 3 14
GO:0007017 microtubule-based process 2 49
GO:0007018 microtubule-based movement 3 49
GO:0009987 cellular process 1 49
GO:0048870 cell motility 2 14
GO:0060285 cilium-dependent cell motility 4 14
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 49
GO:0003774 cytoskeletal motor activity 1 49
GO:0003777 microtubule motor activity 2 49
GO:0003824 catalytic activity 1 14
GO:0005488 binding 1 49
GO:0005515 protein binding 2 30
GO:0005524 ATP binding 5 49
GO:0008569 minus-end-directed microtubule motor activity 3 49
GO:0016462 pyrophosphatase activity 5 14
GO:0016787 hydrolase activity 2 14
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1392 1396 PF00656 0.449
CLV_C14_Caspase3-7 1676 1680 PF00656 0.360
CLV_C14_Caspase3-7 2584 2588 PF00656 0.368
CLV_C14_Caspase3-7 3073 3077 PF00656 0.435
CLV_C14_Caspase3-7 3193 3197 PF00656 0.462
CLV_C14_Caspase3-7 3419 3423 PF00656 0.584
CLV_C14_Caspase3-7 3459 3463 PF00656 0.477
CLV_C14_Caspase3-7 3706 3710 PF00656 0.329
CLV_C14_Caspase3-7 3835 3839 PF00656 0.561
CLV_C14_Caspase3-7 3927 3931 PF00656 0.556
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P8F1 Leptomonas seymouri 33% 100%
A0A0N1HVV7 Leptomonas seymouri 69% 100%
A0A0N1I0K3 Leptomonas seymouri 33% 100%
A0A0N1I4F9 Leptomonas seymouri 39% 100%
A0A0N1PBB8 Leptomonas seymouri 29% 92%
A0A0N1PCN0 Leptomonas seymouri 32% 89%
A0A0N1PCS5 Leptomonas seymouri 35% 99%
A0A0S4IM00 Bodo saltans 35% 96%
A0A0S4IXG4 Bodo saltans 32% 92%
A0A0S4J0Y0 Bodo saltans 28% 91%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS