Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H7P7_LEIBR

TriTrypDb:

LbrM.14.0910 , LBRM2903_140014900

Length:

894

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7P7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7P7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	328	332	PF00656	0.539
CLV_C14_Caspase3-7	482	486	PF00656	0.560
CLV_NRD_NRD_1	439	441	PF00675	0.574
CLV_NRD_NRD_1	546	548	PF00675	0.646
CLV_NRD_NRD_1	549	551	PF00675	0.619
CLV_PCSK_FUR_1	547	551	PF00082	0.661
CLV_PCSK_KEX2_1	439	441	PF00082	0.574
CLV_PCSK_KEX2_1	545	547	PF00082	0.670
CLV_PCSK_KEX2_1	549	551	PF00082	0.631
CLV_PCSK_PC1ET2_1	545	547	PF00082	0.670
CLV_PCSK_SKI1_1	130	134	PF00082	0.543
CLV_PCSK_SKI1_1	293	297	PF00082	0.686
CLV_PCSK_SKI1_1	552	556	PF00082	0.548
CLV_PCSK_SKI1_1	718	722	PF00082	0.551
DEG_Nend_Nbox_1	1	3	PF02207	0.638
DEG_SCF_FBW7_1	193	200	PF00400	0.556
DEG_SCF_FBW7_1	65	72	PF00400	0.679
DOC_CKS1_1	250	255	PF01111	0.532
DOC_CKS1_1	370	375	PF01111	0.665
DOC_CYCLIN_yCln2_LP_2	190	193	PF00134	0.536
DOC_CYCLIN_yCln2_LP_2	875	881	PF00134	0.494
DOC_MAPK_gen_1	700	710	PF00069	0.467
DOC_PP2B_LxvP_1	109	112	PF13499	0.559
DOC_PP2B_LxvP_1	190	193	PF13499	0.536
DOC_PP2B_LxvP_1	569	572	PF13499	0.580
DOC_PP2B_LxvP_1	875	878	PF13499	0.500
DOC_PP2B_PxIxI_1	60	66	PF00149	0.655
DOC_PP4_FxxP_1	223	226	PF00568	0.565
DOC_USP7_MATH_1	145	149	PF00917	0.657
DOC_USP7_MATH_1	197	201	PF00917	0.567
DOC_USP7_MATH_1	226	230	PF00917	0.547
DOC_USP7_MATH_1	38	42	PF00917	0.725
DOC_USP7_MATH_1	383	387	PF00917	0.759
DOC_USP7_MATH_1	4	8	PF00917	0.614
DOC_USP7_MATH_1	404	408	PF00917	0.650
DOC_USP7_MATH_1	537	541	PF00917	0.568
DOC_USP7_MATH_1	562	566	PF00917	0.695
DOC_USP7_MATH_1	575	579	PF00917	0.629
DOC_USP7_MATH_1	589	593	PF00917	0.590
DOC_USP7_MATH_1	844	848	PF00917	0.625
DOC_USP7_UBL2_3	541	545	PF12436	0.565
DOC_WW_Pin1_4	153	158	PF00397	0.728
DOC_WW_Pin1_4	193	198	PF00397	0.574
DOC_WW_Pin1_4	228	233	PF00397	0.636
DOC_WW_Pin1_4	238	243	PF00397	0.572
DOC_WW_Pin1_4	249	254	PF00397	0.557
DOC_WW_Pin1_4	258	263	PF00397	0.498
DOC_WW_Pin1_4	297	302	PF00397	0.642
DOC_WW_Pin1_4	307	312	PF00397	0.583
DOC_WW_Pin1_4	34	39	PF00397	0.657
DOC_WW_Pin1_4	346	351	PF00397	0.692
DOC_WW_Pin1_4	365	370	PF00397	0.529
DOC_WW_Pin1_4	397	402	PF00397	0.758
DOC_WW_Pin1_4	409	414	PF00397	0.657
DOC_WW_Pin1_4	447	452	PF00397	0.584
DOC_WW_Pin1_4	468	473	PF00397	0.693
DOC_WW_Pin1_4	494	499	PF00397	0.606
DOC_WW_Pin1_4	590	595	PF00397	0.482
DOC_WW_Pin1_4	65	70	PF00397	0.681
DOC_WW_Pin1_4	666	671	PF00397	0.620
DOC_WW_Pin1_4	673	678	PF00397	0.603
DOC_WW_Pin1_4	801	806	PF00397	0.606
LIG_14-3-3_CanoR_1	130	137	PF00244	0.610
LIG_14-3-3_CanoR_1	174	183	PF00244	0.599
LIG_14-3-3_CanoR_1	206	210	PF00244	0.624
LIG_14-3-3_CanoR_1	221	226	PF00244	0.532
LIG_14-3-3_CanoR_1	278	283	PF00244	0.693
LIG_14-3-3_CanoR_1	287	292	PF00244	0.751
LIG_14-3-3_CanoR_1	83	89	PF00244	0.592
LIG_CSL_BTD_1	790	793	PF09270	0.576
LIG_deltaCOP1_diTrp_1	769	777	PF00928	0.510
LIG_EVH1_1	569	573	PF00568	0.586
LIG_FHA_1	104	110	PF00498	0.572
LIG_FHA_1	131	137	PF00498	0.627
LIG_FHA_1	157	163	PF00498	0.579
LIG_FHA_1	182	188	PF00498	0.555
LIG_FHA_1	294	300	PF00498	0.691
LIG_FHA_1	328	334	PF00498	0.593
LIG_FHA_1	38	44	PF00498	0.637
LIG_FHA_1	387	393	PF00498	0.557
LIG_FHA_1	575	581	PF00498	0.518
LIG_FHA_1	607	613	PF00498	0.505
LIG_FHA_1	69	75	PF00498	0.661
LIG_FHA_1	739	745	PF00498	0.534
LIG_FHA_1	746	752	PF00498	0.508
LIG_FHA_1	89	95	PF00498	0.709
LIG_FHA_1	96	102	PF00498	0.667
LIG_FHA_2	194	200	PF00498	0.605
LIG_FHA_2	229	235	PF00498	0.637
LIG_FHA_2	385	391	PF00498	0.551
LIG_FHA_2	480	486	PF00498	0.566
LIG_IBAR_NPY_1	60	62	PF08397	0.671
LIG_IRF3_LxIS_1	256	261	PF10401	0.532
LIG_IRF3_LxIS_1	805	811	PF10401	0.534
LIG_LIR_Apic_2	565	571	PF02991	0.626
LIG_LIR_Apic_2	790	794	PF02991	0.576
LIG_LIR_Apic_2	821	827	PF02991	0.506
LIG_LIR_Gen_1	177	187	PF02991	0.656
LIG_LIR_Gen_1	41	52	PF02991	0.615
LIG_LIR_Gen_1	434	442	PF02991	0.545
LIG_LIR_Gen_1	598	608	PF02991	0.530
LIG_LIR_Gen_1	705	715	PF02991	0.513
LIG_LIR_Gen_1	770	781	PF02991	0.678
LIG_LIR_Gen_1	863	873	PF02991	0.516
LIG_LIR_Nem_3	177	183	PF02991	0.541
LIG_LIR_Nem_3	41	47	PF02991	0.616
LIG_LIR_Nem_3	434	438	PF02991	0.541
LIG_LIR_Nem_3	595	600	PF02991	0.707
LIG_LIR_Nem_3	705	710	PF02991	0.460
LIG_LIR_Nem_3	769	775	PF02991	0.699
LIG_LIR_Nem_3	863	869	PF02991	0.516
LIG_LIR_Nem_3	889	894	PF02991	0.469
LIG_MYND_1	397	401	PF01753	0.554
LIG_Pex14_1	771	775	PF04695	0.528
LIG_Pex14_2	773	777	PF04695	0.541
LIG_SH2_CRK	180	184	PF00017	0.538
LIG_SH2_CRK	376	380	PF00017	0.553
LIG_SH2_CRK	44	48	PF00017	0.656
LIG_SH2_CRK	601	605	PF00017	0.520
LIG_SH2_CRK	608	612	PF00017	0.530
LIG_SH2_CRK	707	711	PF00017	0.454
LIG_SH2_GRB2like	144	147	PF00017	0.566
LIG_SH2_GRB2like	376	379	PF00017	0.556
LIG_SH2_NCK_1	180	184	PF00017	0.538
LIG_SH2_NCK_1	648	652	PF00017	0.511
LIG_SH2_NCK_1	866	870	PF00017	0.516
LIG_SH2_PTP2	259	262	PF00017	0.534
LIG_SH2_PTP2	62	65	PF00017	0.687
LIG_SH2_PTP2	775	778	PF00017	0.523
LIG_SH2_SRC	144	147	PF00017	0.617
LIG_SH2_SRC	180	183	PF00017	0.540
LIG_SH2_SRC	568	571	PF00017	0.610
LIG_SH2_SRC	820	823	PF00017	0.510
LIG_SH2_SRC	866	869	PF00017	0.517
LIG_SH2_STAP1	601	605	PF00017	0.520
LIG_SH2_STAP1	608	612	PF00017	0.530
LIG_SH2_STAP1	820	824	PF00017	0.513
LIG_SH2_STAT5	259	262	PF00017	0.558
LIG_SH2_STAT5	568	571	PF00017	0.610
LIG_SH2_STAT5	608	611	PF00017	0.648
LIG_SH2_STAT5	62	65	PF00017	0.856
LIG_SH2_STAT5	687	690	PF00017	0.638
LIG_SH2_STAT5	775	778	PF00017	0.548
LIG_SH2_STAT5	886	889	PF00017	0.499
LIG_SH3_1	567	573	PF00018	0.605
LIG_SH3_3	250	256	PF00018	0.528
LIG_SH3_3	347	353	PF00018	0.674
LIG_SH3_3	435	441	PF00018	0.804
LIG_SH3_3	567	573	PF00018	0.647
LIG_SH3_3	664	670	PF00018	0.519
LIG_SH3_3	671	677	PF00018	0.516
LIG_SH3_3	696	702	PF00018	0.613
LIG_SH3_3	724	730	PF00018	0.531
LIG_SH3_3	746	752	PF00018	0.521
LIG_SH3_3	867	873	PF00018	0.583
LIG_SH3_3	875	881	PF00018	0.516
LIG_SUMO_SIM_anti_2	316	322	PF11976	0.527
LIG_WW_1	373	376	PF00397	0.661
LIG_WW_1	883	886	PF00397	0.561
MOD_CDC14_SPxK_1	349	352	PF00782	0.681
MOD_CDC14_SPxK_1	450	453	PF00782	0.574
MOD_CDK_SPK_2	238	243	PF00069	0.546
MOD_CDK_SPK_2	409	414	PF00069	0.570
MOD_CDK_SPxK_1	346	352	PF00069	0.690
MOD_CDK_SPxK_1	447	453	PF00069	0.581
MOD_CDK_SPxxK_3	494	501	PF00069	0.573
MOD_CK1_1	148	154	PF00069	0.683
MOD_CK1_1	156	162	PF00069	0.631
MOD_CK1_1	169	175	PF00069	0.611
MOD_CK1_1	224	230	PF00069	0.645
MOD_CK1_1	241	247	PF00069	0.521
MOD_CK1_1	277	283	PF00069	0.600
MOD_CK1_1	300	306	PF00069	0.538
MOD_CK1_1	307	313	PF00069	0.528
MOD_CK1_1	327	333	PF00069	0.606
MOD_CK1_1	368	374	PF00069	0.585
MOD_CK1_1	386	392	PF00069	0.725
MOD_CK1_1	403	409	PF00069	0.632
MOD_CK1_1	423	429	PF00069	0.667
MOD_CK1_1	46	52	PF00069	0.748
MOD_CK1_1	5	11	PF00069	0.652
MOD_CK1_1	530	536	PF00069	0.627
MOD_CK1_1	55	61	PF00069	0.594
MOD_CK1_1	592	598	PF00069	0.669
MOD_CK1_1	662	668	PF00069	0.565
MOD_CK2_1	193	199	PF00069	0.622
MOD_CK2_1	228	234	PF00069	0.638
MOD_CK2_1	329	335	PF00069	0.598
MOD_CK2_1	384	390	PF00069	0.613
MOD_CK2_1	512	518	PF00069	0.556
MOD_CK2_1	861	867	PF00069	0.516
MOD_Cter_Amidation	541	544	PF01082	0.566
MOD_DYRK1A_RPxSP_1	238	242	PF00069	0.544
MOD_GlcNHglycan	101	104	PF01048	0.626
MOD_GlcNHglycan	176	179	PF01048	0.621
MOD_GlcNHglycan	228	231	PF01048	0.574
MOD_GlcNHglycan	243	246	PF01048	0.607
MOD_GlcNHglycan	39	43	PF01048	0.708
MOD_GlcNHglycan	4	7	PF01048	0.639
MOD_GlcNHglycan	402	405	PF01048	0.684
MOD_GlcNHglycan	406	409	PF01048	0.647
MOD_GlcNHglycan	422	425	PF01048	0.616
MOD_GlcNHglycan	472	475	PF01048	0.609
MOD_GlcNHglycan	587	590	PF01048	0.621
MOD_GlcNHglycan	594	597	PF01048	0.508
MOD_GlcNHglycan	655	658	PF01048	0.546
MOD_GlcNHglycan	664	667	PF01048	0.736
MOD_GlcNHglycan	690	693	PF01048	0.733
MOD_GlcNHglycan	745	748	PF01048	0.564
MOD_GlcNHglycan	759	762	PF01048	0.559
MOD_GlcNHglycan	891	894	PF01048	0.487
MOD_GSK3_1	148	155	PF00069	0.717
MOD_GSK3_1	162	169	PF00069	0.628
MOD_GSK3_1	193	200	PF00069	0.645
MOD_GSK3_1	20	27	PF00069	0.576
MOD_GSK3_1	224	231	PF00069	0.618
MOD_GSK3_1	266	273	PF00069	0.635
MOD_GSK3_1	274	281	PF00069	0.631
MOD_GSK3_1	283	290	PF00069	0.646
MOD_GSK3_1	293	300	PF00069	0.765
MOD_GSK3_1	301	308	PF00069	0.658
MOD_GSK3_1	323	330	PF00069	0.786
MOD_GSK3_1	34	41	PF00069	0.756
MOD_GSK3_1	342	349	PF00069	0.563
MOD_GSK3_1	365	372	PF00069	0.675
MOD_GSK3_1	386	393	PF00069	0.735
MOD_GSK3_1	400	407	PF00069	0.624
MOD_GSK3_1	46	53	PF00069	0.652
MOD_GSK3_1	5	12	PF00069	0.653
MOD_GSK3_1	585	592	PF00069	0.510
MOD_GSK3_1	623	630	PF00069	0.492
MOD_GSK3_1	65	72	PF00069	0.679
MOD_GSK3_1	662	669	PF00069	0.637
MOD_GSK3_1	93	100	PF00069	0.724
MOD_N-GLC_1	145	150	PF02516	0.667
MOD_N-GLC_1	167	172	PF02516	0.594
MOD_N-GLC_1	197	202	PF02516	0.568
MOD_N-GLC_1	324	329	PF02516	0.526
MOD_N-GLC_1	384	389	PF02516	0.637
MOD_N-GLC_1	50	55	PF02516	0.654
MOD_N-GLC_1	589	594	PF02516	0.496
MOD_N-GLC_2	378	380	PF02516	0.551
MOD_N-GLC_2	623	625	PF02516	0.498
MOD_NEK2_1	114	119	PF00069	0.615
MOD_NEK2_1	162	167	PF00069	0.677
MOD_NEK2_1	2	7	PF00069	0.637
MOD_NEK2_1	271	276	PF00069	0.694
MOD_NEK2_1	282	287	PF00069	0.656
MOD_NEK2_1	329	334	PF00069	0.659
MOD_NEK2_1	384	389	PF00069	0.664
MOD_NEK2_1	43	48	PF00069	0.649
MOD_NEK2_1	442	447	PF00069	0.554
MOD_NEK2_1	627	632	PF00069	0.551
MOD_NEK2_1	659	664	PF00069	0.518
MOD_NEK2_1	688	693	PF00069	0.627
MOD_NEK2_1	808	813	PF00069	0.574
MOD_NEK2_1	9	14	PF00069	0.610
MOD_NEK2_2	205	210	PF00069	0.571
MOD_NEK2_2	562	567	PF00069	0.649
MOD_NEK2_2	886	891	PF00069	0.491
MOD_PIKK_1	103	109	PF00454	0.559
MOD_PIKK_1	135	141	PF00454	0.535
MOD_PIKK_1	384	390	PF00454	0.666
MOD_PIKK_1	69	75	PF00454	0.562
MOD_PIKK_1	738	744	PF00454	0.554
MOD_PIKK_1	828	834	PF00454	0.504
MOD_PIKK_1	9	15	PF00454	0.666
MOD_PK_1	287	293	PF00069	0.757
MOD_PKA_2	114	120	PF00069	0.571
MOD_PKA_2	148	154	PF00069	0.750
MOD_PKA_2	166	172	PF00069	0.594
MOD_PKA_2	205	211	PF00069	0.572
MOD_PKA_2	277	283	PF00069	0.709
MOD_PKA_2	82	88	PF00069	0.577
MOD_PKA_2	9	15	PF00069	0.666
MOD_Plk_1	324	330	PF00069	0.526
MOD_Plk_1	38	44	PF00069	0.574
MOD_Plk_1	69	75	PF00069	0.679
MOD_Plk_1	820	826	PF00069	0.512
MOD_Plk_2-3	390	396	PF00069	0.568
MOD_Plk_4	26	32	PF00069	0.544
MOD_Plk_4	575	581	PF00069	0.518
MOD_Plk_4	675	681	PF00069	0.642
MOD_Plk_4	745	751	PF00069	0.540
MOD_Plk_4	767	773	PF00069	0.642
MOD_Plk_4	861	867	PF00069	0.541
MOD_Plk_4	886	892	PF00069	0.470
MOD_ProDKin_1	153	159	PF00069	0.729
MOD_ProDKin_1	193	199	PF00069	0.578
MOD_ProDKin_1	228	234	PF00069	0.638
MOD_ProDKin_1	238	244	PF00069	0.572
MOD_ProDKin_1	249	255	PF00069	0.553
MOD_ProDKin_1	258	264	PF00069	0.501
MOD_ProDKin_1	297	303	PF00069	0.641
MOD_ProDKin_1	307	313	PF00069	0.582
MOD_ProDKin_1	34	40	PF00069	0.656
MOD_ProDKin_1	346	352	PF00069	0.690
MOD_ProDKin_1	365	371	PF00069	0.529
MOD_ProDKin_1	397	403	PF00069	0.760
MOD_ProDKin_1	409	415	PF00069	0.654
MOD_ProDKin_1	447	453	PF00069	0.584
MOD_ProDKin_1	468	474	PF00069	0.694
MOD_ProDKin_1	494	500	PF00069	0.607
MOD_ProDKin_1	590	596	PF00069	0.478
MOD_ProDKin_1	65	71	PF00069	0.680
MOD_ProDKin_1	666	672	PF00069	0.624
MOD_ProDKin_1	673	679	PF00069	0.602
MOD_ProDKin_1	801	807	PF00069	0.603
MOD_SUMO_rev_2	423	432	PF00179	0.554
TRG_DiLeu_BaLyEn_6	109	114	PF01217	0.559
TRG_DiLeu_BaLyEn_6	607	612	PF01217	0.527
TRG_ENDOCYTIC_2	180	183	PF00928	0.656
TRG_ENDOCYTIC_2	376	379	PF00928	0.556
TRG_ENDOCYTIC_2	435	438	PF00928	0.542
TRG_ENDOCYTIC_2	44	47	PF00928	0.802
TRG_ENDOCYTIC_2	600	603	PF00928	0.533
TRG_ENDOCYTIC_2	608	611	PF00928	0.531
TRG_ENDOCYTIC_2	62	65	PF00928	0.856
TRG_ENDOCYTIC_2	707	710	PF00928	0.526
TRG_ENDOCYTIC_2	866	869	PF00928	0.517
TRG_ER_diArg_1	359	362	PF00400	0.559
TRG_ER_diArg_1	438	440	PF00400	0.581
TRG_ER_diArg_1	546	549	PF00400	0.661
TRG_NLS_MonoCore_2	542	547	PF00514	0.667
TRG_NLS_MonoExtC_3	542	547	PF00514	0.676
TRG_NLS_MonoExtN_4	541	548	PF00514	0.665
TRG_NLS_MonoExtN_4	549	556	PF00514	0.602
TRG_Pf-PMV_PEXEL_1	610	614	PF00026	0.612

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IID6	Leishmania donovani	61%	100%
A4HW36	Leishmania infantum	62%	100%
E9APT9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	100%
Q4QFP1	Leishmania major	59%	96%