zf-LSD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

LSD1 zinc finger, putative

Species:

Leishmania braziliensis

UniProt:

A4H7M0_LEIBR

TriTrypDb:

LbrM.14.0610 , LBRM2903_140011600

Length:

225

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

A4H7M0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7M0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	165	169	PF00656	0.639
CLV_NRD_NRD_1	122	124	PF00675	0.807
CLV_NRD_NRD_1	142	144	PF00675	0.470
CLV_NRD_NRD_1	174	176	PF00675	0.663
CLV_NRD_NRD_1	183	185	PF00675	0.670
CLV_PCSK_FUR_1	181	185	PF00082	0.552
CLV_PCSK_KEX2_1	122	124	PF00082	0.807
CLV_PCSK_KEX2_1	141	143	PF00082	0.507
CLV_PCSK_KEX2_1	174	176	PF00082	0.669
CLV_PCSK_KEX2_1	183	185	PF00082	0.664
CLV_PCSK_SKI1_1	13	17	PF00082	0.513
DEG_Nend_Nbox_1	1	3	PF02207	0.690
DOC_CYCLIN_RxL_1	139	150	PF00134	0.545
DOC_CYCLIN_yCln2_LP_2	15	21	PF00134	0.411
DOC_CYCLIN_yCln2_LP_2	73	76	PF00134	0.585
DOC_MAPK_gen_1	156	163	PF00069	0.550
DOC_MAPK_MEF2A_6	213	220	PF00069	0.753
DOC_PP1_RVXF_1	140	147	PF00149	0.545
DOC_PP2B_LxvP_1	101	104	PF13499	0.535
DOC_PP2B_LxvP_1	49	52	PF13499	0.589
DOC_PP2B_LxvP_1	73	76	PF13499	0.585
DOC_USP7_MATH_1	118	122	PF00917	0.547
DOC_USP7_MATH_1	200	204	PF00917	0.605
DOC_WW_Pin1_4	133	138	PF00397	0.550
DOC_WW_Pin1_4	196	201	PF00397	0.605
LIG_14-3-3_CanoR_1	122	128	PF00244	0.654
LIG_14-3-3_CanoR_1	13	18	PF00244	0.411
LIG_14-3-3_CanoR_1	141	147	PF00244	0.657
LIG_BIR_III_2	197	201	PF00653	0.555
LIG_EVH1_1	101	105	PF00568	0.537
LIG_EVH1_1	74	78	PF00568	0.653
LIG_FHA_1	14	20	PF00498	0.513
LIG_FHA_1	203	209	PF00498	0.721
LIG_FHA_1	215	221	PF00498	0.632
LIG_FHA_1	53	59	PF00498	0.642
LIG_FHA_2	63	69	PF00498	0.544
LIG_MYND_1	99	103	PF01753	0.784
LIG_SH2_STAT3	9	12	PF00017	0.411
LIG_SH2_STAT5	139	142	PF00017	0.547
LIG_SH2_STAT5	95	98	PF00017	0.694
LIG_SH3_3	72	78	PF00018	0.649
LIG_SH3_3	93	99	PF00018	0.684
LIG_SUMO_SIM_anti_2	55	60	PF11976	0.698
LIG_SUMO_SIM_par_1	216	222	PF11976	0.644
LIG_TRAF2_1	192	195	PF00917	0.553
LIG_TRAF2_2	192	197	PF00917	0.556
LIG_WW_2	75	78	PF00397	0.658
LIG_WW_3	103	107	PF00397	0.764
MOD_CK1_1	97	103	PF00069	0.688
MOD_CK2_1	142	148	PF00069	0.797
MOD_GlcNHglycan	202	205	PF01048	0.707
MOD_GlcNHglycan	33	36	PF01048	0.475
MOD_GSK3_1	118	125	PF00069	0.663
MOD_GSK3_1	131	138	PF00069	0.580
MOD_GSK3_1	196	203	PF00069	0.737
MOD_NEK2_1	219	224	PF00069	0.654
MOD_NEK2_1	28	33	PF00069	0.261
MOD_NEK2_1	38	43	PF00069	0.490
MOD_NEK2_2	20	25	PF00069	0.411
MOD_PKA_1	122	128	PF00069	0.806
MOD_PKA_1	142	148	PF00069	0.466
MOD_PKA_1	183	189	PF00069	0.678
MOD_PKA_2	122	128	PF00069	0.764
MOD_PKA_2	142	148	PF00069	0.466
MOD_PKA_2	183	189	PF00069	0.713
MOD_PKB_1	133	141	PF00069	0.763
MOD_PKB_1	181	189	PF00069	0.560
MOD_Plk_4	135	141	PF00069	0.543
MOD_Plk_4	214	220	PF00069	0.648
MOD_Plk_4	89	95	PF00069	0.517
MOD_ProDKin_1	133	139	PF00069	0.550
MOD_ProDKin_1	196	202	PF00069	0.604
MOD_SUMO_rev_2	88	93	PF00179	0.668
TRG_DiLeu_BaEn_3	88	94	PF01217	0.508
TRG_ER_diArg_1	140	143	PF00400	0.616
TRG_ER_diArg_1	173	175	PF00400	0.664
TRG_ER_diArg_1	25	28	PF00400	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B1	Leptomonas seymouri	48%	100%
A0A3Q8IBZ4	Leishmania donovani	68%	100%
A4HW05	Leishmania infantum	68%	100%
E9APQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	100%
Q4QFS2	Leishmania major	67%	100%