LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H7L8_LEIBR
TriTrypDb:
LbrM.14.0590 , LBRM2903_140011400 *
Length:
467

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0005739 mitochondrion 5 1
GO:0020023 kinetoplast 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4H7L8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7L8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 389 393 PF00656 0.762
CLV_C14_Caspase3-7 81 85 PF00656 0.734
CLV_NRD_NRD_1 205 207 PF00675 0.529
CLV_NRD_NRD_1 231 233 PF00675 0.449
CLV_NRD_NRD_1 239 241 PF00675 0.469
CLV_NRD_NRD_1 355 357 PF00675 0.521
CLV_NRD_NRD_1 413 415 PF00675 0.660
CLV_PCSK_KEX2_1 231 233 PF00082 0.449
CLV_PCSK_KEX2_1 239 241 PF00082 0.469
CLV_PCSK_KEX2_1 355 357 PF00082 0.521
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PAF5 Leptomonas seymouri 51% 100%
A0A3Q8I8S7 Leishmania donovani 74% 100%
A0A3R7RMG7 Trypanosoma rangeli 41% 100%
A4HW03 Leishmania infantum 74% 100%
C9ZT20 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 100%
E9APQ5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 93%
Q4QFS4 Leishmania major 72% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS