Putative chaperonin TCP20

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

chaperonin TCP20, putative

Species:

Leishmania braziliensis

UniProt:

A4H7F6_LEIBR

TriTrypDb:

LbrM.13.1520 , LBRM2903_130021400

Length:

538

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 5

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	12
GO:0005832	chaperonin-containing T-complex	4	1
GO:0032991	protein-containing complex	1	1
GO:0101031	protein folding chaperone complex	3	1
GO:0110165	cellular anatomical entity	1	12
GO:0140535	intracellular protein-containing complex	2	1

Previous1Next

Expansion

Sequence features

A4H7F6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7F6

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006457	protein folding	2	1
GO:0009987	cellular process	1	1

Previous1Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005515	protein binding	2	12
GO:0005524	ATP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12

Previous1 2 3Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	14	16	PF00675	0.483
CLV_NRD_NRD_1	146	148	PF00675	0.415
CLV_NRD_NRD_1	265	267	PF00675	0.358
CLV_NRD_NRD_1	317	319	PF00675	0.358
CLV_NRD_NRD_1	321	323	PF00675	0.358
CLV_NRD_NRD_1	476	478	PF00675	0.447
CLV_NRD_NRD_1	532	534	PF00675	0.560
CLV_PCSK_FUR_1	318	322	PF00082	0.374
CLV_PCSK_KEX2_1	146	148	PF00082	0.374
CLV_PCSK_KEX2_1	317	319	PF00082	0.358

Previous1 2 3 4 5…18Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2U4	Leptomonas seymouri	27%	98%
A0A0N1HUM6	Leptomonas seymouri	27%	100%
A0A0N1HUW6	Leptomonas seymouri	26%	98%
A0A0N1HXN1	Leptomonas seymouri	91%	100%
A0A0N1I104	Leptomonas seymouri	28%	94%
A0A0N1I2L2	Leptomonas seymouri	30%	100%
A0A0N1II94	Leptomonas seymouri	27%	98%
A0A0N1IM41	Leptomonas seymouri	27%	100%
A0A0S4IN05	Bodo saltans	22%	91%
A0A0S4IWM5	Bodo saltans	25%	98%

Previous1 2 3 4 5…36Next