LeishMANIAdb
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DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed DNA polymerase
Gene product:
mitochondrial DNA polymerase I protein D, putative
Species:
Leishmania braziliensis
UniProt:
A4H7F3_LEIBR
TriTrypDb:
LbrM.13.1490 , LBRM2903_130021100 *
Length:
1578

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H7F3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006260 DNA replication 5 12
GO:0006261 DNA-templated DNA replication 6 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0033554 cellular response to stress 3 1
GO:0050896 response to stimulus 1 1
GO:0051716 cellular response to stimulus 2 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003887 DNA-directed DNA polymerase activity 5 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0034061 DNA polymerase activity 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12
GO:0004518 nuclease activity 4 1
GO:0004527 exonuclease activity 5 1
GO:0008408 3'-5' exonuclease activity 6 1
GO:0016787 hydrolase activity 2 1
GO:0016788 hydrolase activity, acting on ester bonds 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1017 1021 PF00656 0.359
CLV_C14_Caspase3-7 1120 1124 PF00656 0.523
CLV_C14_Caspase3-7 1226 1230 PF00656 0.537
CLV_C14_Caspase3-7 535 539 PF00656 0.523
CLV_C14_Caspase3-7 842 846 PF00656 0.554
CLV_C14_Caspase3-7 873 877 PF00656 0.355
CLV_C14_Caspase3-7 926 930 PF00656 0.476
CLV_MEL_PAP_1 189 195 PF00089 0.445
CLV_MEL_PAP_1 223 229 PF00089 0.383
CLV_NRD_NRD_1 1036 1038 PF00675 0.300
CLV_NRD_NRD_1 1089 1091 PF00675 0.577
CLV_NRD_NRD_1 1111 1113 PF00675 0.408
CLV_NRD_NRD_1 1125 1127 PF00675 0.299
CLV_NRD_NRD_1 1179 1181 PF00675 0.290
CLV_NRD_NRD_1 1461 1463 PF00675 0.362
CLV_NRD_NRD_1 191 193 PF00675 0.440
CLV_NRD_NRD_1 198 200 PF00675 0.454
CLV_NRD_NRD_1 210 212 PF00675 0.216
CLV_NRD_NRD_1 247 249 PF00675 0.484
CLV_NRD_NRD_1 352 354 PF00675 0.513
CLV_NRD_NRD_1 444 446 PF00675 0.549
CLV_NRD_NRD_1 465 467 PF00675 0.484
CLV_NRD_NRD_1 478 480 PF00675 0.276
CLV_NRD_NRD_1 509 511 PF00675 0.484
CLV_NRD_NRD_1 570 572 PF00675 0.357
CLV_NRD_NRD_1 574 576 PF00675 0.361
CLV_NRD_NRD_1 708 710 PF00675 0.514
CLV_NRD_NRD_1 723 725 PF00675 0.346
CLV_NRD_NRD_1 824 826 PF00675 0.395
CLV_NRD_NRD_1 835 837 PF00675 0.439
CLV_NRD_NRD_1 861 863 PF00675 0.369
CLV_PCSK_FUR_1 1109 1113 PF00082 0.489
CLV_PCSK_FUR_1 479 483 PF00082 0.425
CLV_PCSK_KEX2_1 103 105 PF00082 0.395
CLV_PCSK_KEX2_1 1036 1038 PF00082 0.526
CLV_PCSK_KEX2_1 1094 1096 PF00082 0.595
CLV_PCSK_KEX2_1 1111 1113 PF00082 0.395
CLV_PCSK_KEX2_1 1127 1129 PF00082 0.322
CLV_PCSK_KEX2_1 1179 1181 PF00082 0.362
CLV_PCSK_KEX2_1 1326 1328 PF00082 0.276
CLV_PCSK_KEX2_1 191 193 PF00082 0.457
CLV_PCSK_KEX2_1 210 212 PF00082 0.216
CLV_PCSK_KEX2_1 247 249 PF00082 0.414
CLV_PCSK_KEX2_1 352 354 PF00082 0.578
CLV_PCSK_KEX2_1 403 405 PF00082 0.554
CLV_PCSK_KEX2_1 444 446 PF00082 0.549
CLV_PCSK_KEX2_1 465 467 PF00082 0.429
CLV_PCSK_KEX2_1 478 480 PF00082 0.286
CLV_PCSK_KEX2_1 481 483 PF00082 0.430
CLV_PCSK_KEX2_1 509 511 PF00082 0.484
CLV_PCSK_KEX2_1 570 572 PF00082 0.335
CLV_PCSK_KEX2_1 574 576 PF00082 0.356
CLV_PCSK_KEX2_1 708 710 PF00082 0.607
CLV_PCSK_KEX2_1 835 837 PF00082 0.510
CLV_PCSK_KEX2_1 848 850 PF00082 0.354
CLV_PCSK_KEX2_1 861 863 PF00082 0.301
CLV_PCSK_PC1ET2_1 103 105 PF00082 0.462
CLV_PCSK_PC1ET2_1 1094 1096 PF00082 0.605
CLV_PCSK_PC1ET2_1 1127 1129 PF00082 0.443
CLV_PCSK_PC1ET2_1 1326 1328 PF00082 0.276
CLV_PCSK_PC1ET2_1 403 405 PF00082 0.590
CLV_PCSK_PC1ET2_1 481 483 PF00082 0.432
CLV_PCSK_PC1ET2_1 848 850 PF00082 0.528
CLV_PCSK_PC7_1 1090 1096 PF00082 0.466
CLV_PCSK_PC7_1 570 576 PF00082 0.381
CLV_PCSK_SKI1_1 100 104 PF00082 0.429
CLV_PCSK_SKI1_1 1047 1051 PF00082 0.426
CLV_PCSK_SKI1_1 1111 1115 PF00082 0.414
CLV_PCSK_SKI1_1 1128 1132 PF00082 0.412
CLV_PCSK_SKI1_1 1278 1282 PF00082 0.276
CLV_PCSK_SKI1_1 1326 1330 PF00082 0.332
CLV_PCSK_SKI1_1 1432 1436 PF00082 0.276
CLV_PCSK_SKI1_1 1442 1446 PF00082 0.276
CLV_PCSK_SKI1_1 1494 1498 PF00082 0.275
CLV_PCSK_SKI1_1 199 203 PF00082 0.516
CLV_PCSK_SKI1_1 21 25 PF00082 0.399
CLV_PCSK_SKI1_1 211 215 PF00082 0.289
CLV_PCSK_SKI1_1 323 327 PF00082 0.387
CLV_PCSK_SKI1_1 364 368 PF00082 0.497
CLV_PCSK_SKI1_1 458 462 PF00082 0.440
CLV_PCSK_SKI1_1 570 574 PF00082 0.346
CLV_PCSK_SKI1_1 724 728 PF00082 0.504
CLV_PCSK_SKI1_1 754 758 PF00082 0.535
CLV_PCSK_SKI1_1 836 840 PF00082 0.574
CLV_PCSK_SKI1_1 862 866 PF00082 0.345
DEG_APCC_DBOX_1 1125 1133 PF00400 0.384
DEG_APCC_DBOX_1 198 206 PF00400 0.576
DEG_APCC_KENBOX_2 1391 1395 PF00400 0.562
DEG_APCC_KENBOX_2 488 492 PF00400 0.399
DEG_COP1_1 1446 1454 PF00400 0.487
DEG_COP1_1 277 287 PF00400 0.475
DEG_ODPH_VHL_1 107 119 PF01847 0.386
DOC_CKS1_1 193 198 PF01111 0.567
DOC_CYCLIN_RxL_1 100 111 PF00134 0.514
DOC_CYCLIN_RxL_1 1045 1054 PF00134 0.498
DOC_CYCLIN_RxL_1 463 474 PF00134 0.341
DOC_CYCLIN_yCln2_LP_2 784 790 PF00134 0.431
DOC_MAPK_gen_1 1033 1042 PF00069 0.533
DOC_MAPK_gen_1 1126 1134 PF00069 0.445
DOC_MAPK_gen_1 1343 1352 PF00069 0.477
DOC_MAPK_gen_1 210 220 PF00069 0.346
DOC_MAPK_gen_1 288 297 PF00069 0.431
DOC_MAPK_gen_1 465 472 PF00069 0.429
DOC_MAPK_gen_1 499 507 PF00069 0.397
DOC_MAPK_gen_1 534 542 PF00069 0.543
DOC_MAPK_gen_1 975 982 PF00069 0.443
DOC_MAPK_HePTP_8 208 220 PF00069 0.368
DOC_MAPK_MEF2A_6 1099 1108 PF00069 0.456
DOC_MAPK_MEF2A_6 1206 1214 PF00069 0.400
DOC_MAPK_MEF2A_6 127 135 PF00069 0.532
DOC_MAPK_MEF2A_6 211 220 PF00069 0.360
DOC_MAPK_MEF2A_6 465 472 PF00069 0.429
DOC_MAPK_NFAT4_5 465 473 PF00069 0.375
DOC_PIKK_1 1310 1317 PF02985 0.478
DOC_PP1_RVXF_1 1346 1353 PF00149 0.400
DOC_PP1_RVXF_1 563 570 PF00149 0.460
DOC_PP2B_LxvP_1 282 285 PF13499 0.458
DOC_PP2B_LxvP_1 540 543 PF13499 0.397
DOC_PP2B_LxvP_1 784 787 PF13499 0.440
DOC_PP4_FxxP_1 1146 1149 PF00568 0.508
DOC_PP4_FxxP_1 193 196 PF00568 0.558
DOC_PP4_FxxP_1 541 544 PF00568 0.377
DOC_PP4_FxxP_1 783 786 PF00568 0.404
DOC_USP7_MATH_1 1018 1022 PF00917 0.583
DOC_USP7_MATH_1 1562 1566 PF00917 0.562
DOC_USP7_MATH_1 175 179 PF00917 0.494
DOC_USP7_MATH_1 384 388 PF00917 0.466
DOC_USP7_MATH_1 750 754 PF00917 0.479
DOC_USP7_MATH_2 1270 1276 PF00917 0.537
DOC_USP7_UBL2_3 1029 1033 PF12436 0.569
DOC_USP7_UBL2_3 1157 1161 PF12436 0.531
DOC_USP7_UBL2_3 880 884 PF12436 0.419
DOC_WW_Pin1_4 1465 1470 PF00397 0.476
DOC_WW_Pin1_4 192 197 PF00397 0.557
DOC_WW_Pin1_4 302 307 PF00397 0.491
DOC_WW_Pin1_4 379 384 PF00397 0.424
LIG_14-3-3_CanoR_1 1010 1019 PF00244 0.594
LIG_14-3-3_CanoR_1 104 108 PF00244 0.239
LIG_14-3-3_CanoR_1 1179 1189 PF00244 0.556
LIG_14-3-3_CanoR_1 1327 1331 PF00244 0.537
LIG_14-3-3_CanoR_1 1373 1381 PF00244 0.581
LIG_14-3-3_CanoR_1 1442 1451 PF00244 0.476
LIG_14-3-3_CanoR_1 1462 1469 PF00244 0.345
LIG_14-3-3_CanoR_1 247 253 PF00244 0.447
LIG_14-3-3_CanoR_1 335 339 PF00244 0.493
LIG_14-3-3_CanoR_1 364 373 PF00244 0.497
LIG_14-3-3_CanoR_1 763 767 PF00244 0.386
LIG_14-3-3_CanoR_1 825 834 PF00244 0.440
LIG_14-3-3_CanoR_1 977 983 PF00244 0.336
LIG_Actin_WH2_2 560 576 PF00022 0.413
LIG_APCC_ABBAyCdc20_2 444 450 PF00400 0.541
LIG_BRCT_BRCA1_1 1463 1467 PF00533 0.476
LIG_BRCT_BRCA1_1 304 308 PF00533 0.396
LIG_BRCT_BRCA1_1 769 773 PF00533 0.443
LIG_CaM_IQ_9 1379 1394 PF13499 0.487
LIG_CaM_IQ_9 437 453 PF13499 0.560
LIG_deltaCOP1_diTrp_1 110 119 PF00928 0.408
LIG_EH_1 484 488 PF12763 0.401
LIG_EH_1 8 12 PF12763 0.558
LIG_eIF4E_1 76 82 PF01652 0.458
LIG_FHA_1 109 115 PF00498 0.365
LIG_FHA_1 1184 1190 PF00498 0.476
LIG_FHA_1 1205 1211 PF00498 0.551
LIG_FHA_1 1230 1236 PF00498 0.476
LIG_FHA_1 1254 1260 PF00498 0.476
LIG_FHA_1 1336 1342 PF00498 0.501
LIG_FHA_1 1507 1513 PF00498 0.501
LIG_FHA_1 235 241 PF00498 0.420
LIG_FHA_1 260 266 PF00498 0.461
LIG_FHA_1 267 273 PF00498 0.461
LIG_FHA_1 335 341 PF00498 0.581
LIG_FHA_1 472 478 PF00498 0.386
LIG_FHA_1 48 54 PF00498 0.371
LIG_FHA_1 611 617 PF00498 0.460
LIG_FHA_1 627 633 PF00498 0.342
LIG_FHA_1 636 642 PF00498 0.389
LIG_FHA_1 646 652 PF00498 0.391
LIG_FHA_1 699 705 PF00498 0.383
LIG_FHA_1 755 761 PF00498 0.494
LIG_FHA_1 763 769 PF00498 0.369
LIG_FHA_1 850 856 PF00498 0.537
LIG_FHA_1 913 919 PF00498 0.420
LIG_FHA_1 957 963 PF00498 0.373
LIG_FHA_1 983 989 PF00498 0.378
LIG_FHA_2 1221 1227 PF00498 0.521
LIG_FHA_2 1444 1450 PF00498 0.476
LIG_FHA_2 148 154 PF00498 0.512
LIG_FHA_2 1509 1515 PF00498 0.476
LIG_FHA_2 229 235 PF00498 0.395
LIG_FHA_2 239 245 PF00498 0.431
LIG_FHA_2 47 53 PF00498 0.393
LIG_FHA_2 588 594 PF00498 0.409
LIG_FHA_2 634 640 PF00498 0.366
LIG_FHA_2 677 683 PF00498 0.399
LIG_FHA_2 686 692 PF00498 0.467
LIG_FHA_2 891 897 PF00498 0.570
LIG_LIR_Apic_2 1144 1149 PF02991 0.508
LIG_LIR_Apic_2 538 544 PF02991 0.404
LIG_LIR_Apic_2 628 633 PF02991 0.434
LIG_LIR_Gen_1 1140 1151 PF02991 0.373
LIG_LIR_Gen_1 115 121 PF02991 0.445
LIG_LIR_Gen_1 1293 1304 PF02991 0.476
LIG_LIR_Gen_1 1334 1344 PF02991 0.476
LIG_LIR_Gen_1 1349 1359 PF02991 0.476
LIG_LIR_Gen_1 1401 1411 PF02991 0.476
LIG_LIR_Gen_1 233 243 PF02991 0.395
LIG_LIR_Gen_1 337 346 PF02991 0.487
LIG_LIR_Gen_1 490 498 PF02991 0.401
LIG_LIR_Gen_1 546 556 PF02991 0.372
LIG_LIR_Gen_1 631 641 PF02991 0.447
LIG_LIR_Gen_1 943 952 PF02991 0.386
LIG_LIR_Nem_3 1020 1025 PF02991 0.542
LIG_LIR_Nem_3 1059 1064 PF02991 0.350
LIG_LIR_Nem_3 1067 1072 PF02991 0.317
LIG_LIR_Nem_3 1140 1146 PF02991 0.372
LIG_LIR_Nem_3 115 119 PF02991 0.393
LIG_LIR_Nem_3 1293 1299 PF02991 0.476
LIG_LIR_Nem_3 1334 1340 PF02991 0.476
LIG_LIR_Nem_3 1349 1355 PF02991 0.476
LIG_LIR_Nem_3 1395 1400 PF02991 0.487
LIG_LIR_Nem_3 1523 1528 PF02991 0.488
LIG_LIR_Nem_3 233 239 PF02991 0.386
LIG_LIR_Nem_3 33 39 PF02991 0.264
LIG_LIR_Nem_3 337 341 PF02991 0.494
LIG_LIR_Nem_3 490 495 PF02991 0.407
LIG_LIR_Nem_3 546 551 PF02991 0.379
LIG_LIR_Nem_3 566 572 PF02991 0.158
LIG_LIR_Nem_3 581 587 PF02991 0.249
LIG_LIR_Nem_3 631 637 PF02991 0.434
LIG_LIR_Nem_3 680 686 PF02991 0.415
LIG_LIR_Nem_3 808 814 PF02991 0.414
LIG_LIR_Nem_3 947 951 PF02991 0.333
LIG_LRP6_Inhibitor_1 336 342 PF00058 0.622
LIG_LYPXL_S_1 1546 1550 PF13949 0.287
LIG_LYPXL_yS_3 1547 1550 PF13949 0.487
LIG_MLH1_MIPbox_1 304 308 PF16413 0.497
LIG_MLH1_MIPbox_1 769 773 PF16413 0.263
LIG_NRBOX 267 273 PF00104 0.435
LIG_PCNA_APIM_2 878 884 PF02747 0.367
LIG_PCNA_PIPBox_1 1540 1549 PF02747 0.400
LIG_PCNA_yPIPBox_3 875 884 PF02747 0.277
LIG_PDZ_Class_1 1573 1578 PF00595 0.572
LIG_Pex14_1 1061 1065 PF04695 0.336
LIG_Pex14_1 112 116 PF04695 0.350
LIG_Pex14_1 580 584 PF04695 0.355
LIG_Pex14_2 1281 1285 PF04695 0.537
LIG_Pex14_2 1431 1435 PF04695 0.487
LIG_PTB_Apo_2 1496 1503 PF02174 0.537
LIG_PTB_Apo_2 1541 1548 PF02174 0.487
LIG_PTB_Apo_2 368 375 PF02174 0.411
LIG_PTB_Apo_2 777 784 PF02174 0.539
LIG_PTB_Phospho_1 1496 1502 PF10480 0.537
LIG_PTB_Phospho_1 1541 1547 PF10480 0.487
LIG_REV1ctd_RIR_1 1428 1435 PF16727 0.501
LIG_REV1ctd_RIR_1 879 885 PF16727 0.370
LIG_SH2_CRK 1118 1122 PF00017 0.428
LIG_SH2_CRK 1502 1506 PF00017 0.487
LIG_SH2_CRK 1525 1529 PF00017 0.562
LIG_SH2_CRK 236 240 PF00017 0.473
LIG_SH2_CRK 36 40 PF00017 0.227
LIG_SH2_CRK 480 484 PF00017 0.419
LIG_SH2_CRK 548 552 PF00017 0.354
LIG_SH2_CRK 634 638 PF00017 0.426
LIG_SH2_CRK 683 687 PF00017 0.446
LIG_SH2_CRK 994 998 PF00017 0.235
LIG_SH2_GRB2like 1117 1120 PF00017 0.437
LIG_SH2_GRB2like 996 999 PF00017 0.244
LIG_SH2_NCK_1 36 40 PF00017 0.480
LIG_SH2_NCK_1 520 524 PF00017 0.550
LIG_SH2_NCK_1 630 634 PF00017 0.451
LIG_SH2_PTP2 1065 1068 PF00017 0.351
LIG_SH2_PTP2 492 495 PF00017 0.441
LIG_SH2_SRC 1065 1068 PF00017 0.351
LIG_SH2_SRC 36 39 PF00017 0.479
LIG_SH2_SRC 520 523 PF00017 0.547
LIG_SH2_SRC 630 633 PF00017 0.424
LIG_SH2_SRC 640 643 PF00017 0.370
LIG_SH2_SRC 814 817 PF00017 0.536
LIG_SH2_SRC 961 964 PF00017 0.491
LIG_SH2_STAP1 1143 1147 PF00017 0.396
LIG_SH2_STAP1 1337 1341 PF00017 0.487
LIG_SH2_STAP1 1414 1418 PF00017 0.537
LIG_SH2_STAP1 236 240 PF00017 0.473
LIG_SH2_STAP1 548 552 PF00017 0.370
LIG_SH2_STAP1 584 588 PF00017 0.277
LIG_SH2_STAT3 1475 1478 PF00017 0.476
LIG_SH2_STAT3 448 451 PF00017 0.592
LIG_SH2_STAT3 609 612 PF00017 0.433
LIG_SH2_STAT3 818 821 PF00017 0.385
LIG_SH2_STAT5 1065 1068 PF00017 0.351
LIG_SH2_STAT5 1167 1170 PF00017 0.476
LIG_SH2_STAT5 1198 1201 PF00017 0.476
LIG_SH2_STAT5 1337 1340 PF00017 0.501
LIG_SH2_STAT5 1443 1446 PF00017 0.476
LIG_SH2_STAT5 236 239 PF00017 0.470
LIG_SH2_STAT5 29 32 PF00017 0.379
LIG_SH2_STAT5 318 321 PF00017 0.531
LIG_SH2_STAT5 361 364 PF00017 0.563
LIG_SH2_STAT5 467 470 PF00017 0.373
LIG_SH2_STAT5 492 495 PF00017 0.434
LIG_SH2_STAT5 511 514 PF00017 0.227
LIG_SH2_STAT5 587 590 PF00017 0.354
LIG_SH2_STAT5 640 643 PF00017 0.384
LIG_SH2_STAT5 76 79 PF00017 0.425
LIG_SH2_STAT5 772 775 PF00017 0.399
LIG_SH2_STAT5 814 817 PF00017 0.416
LIG_SH2_STAT5 961 964 PF00017 0.391
LIG_SH2_STAT5 968 971 PF00017 0.404
LIG_SH2_STAT5 996 999 PF00017 0.444
LIG_SH3_1 7 13 PF00018 0.549
LIG_SH3_2 1024 1029 PF14604 0.567
LIG_SH3_3 1021 1027 PF00018 0.583
LIG_SH3_3 126 132 PF00018 0.484
LIG_SH3_3 1551 1557 PF00018 0.487
LIG_SH3_3 300 306 PF00018 0.378
LIG_SH3_3 480 486 PF00018 0.406
LIG_SH3_3 502 508 PF00018 0.426
LIG_SH3_3 7 13 PF00018 0.561
LIG_SH3_3 880 886 PF00018 0.497
LIG_SUMO_SIM_anti_2 1297 1303 PF11976 0.476
LIG_SUMO_SIM_anti_2 1531 1536 PF11976 0.581
LIG_SUMO_SIM_anti_2 52 58 PF11976 0.492
LIG_SUMO_SIM_par_1 1405 1410 PF11976 0.476
LIG_SUMO_SIM_par_1 237 245 PF11976 0.490
LIG_SUMO_SIM_par_1 468 476 PF11976 0.353
LIG_TRAF2_1 121 124 PF00917 0.377
LIG_TRAF2_1 1571 1574 PF00917 0.347
LIG_TRAF2_1 329 332 PF00917 0.639
LIG_TRAF2_1 393 396 PF00917 0.474
LIG_TYR_ITIM 1335 1340 PF00017 0.476
LIG_TYR_ITIM 34 39 PF00017 0.226
LIG_TYR_ITIM 632 637 PF00017 0.419
LIG_UBA3_1 1131 1137 PF00899 0.523
LIG_UBA3_1 1210 1219 PF00899 0.477
LIG_WRC_WIRS_1 1019 1024 PF05994 0.334
LIG_WRC_WIRS_1 1361 1366 PF05994 0.476
LIG_WRC_WIRS_1 735 740 PF05994 0.416
MOD_CDK_SPxxK_3 192 199 PF00069 0.565
MOD_CK1_1 1012 1018 PF00069 0.552
MOD_CK1_1 1183 1189 PF00069 0.476
MOD_CK1_1 1240 1246 PF00069 0.501
MOD_CK1_1 1376 1382 PF00069 0.476
MOD_CK1_1 1410 1416 PF00069 0.542
MOD_CK1_1 278 284 PF00069 0.454
MOD_CK1_1 47 53 PF00069 0.462
MOD_CK1_1 524 530 PF00069 0.512
MOD_CK1_1 536 542 PF00069 0.353
MOD_CK1_1 635 641 PF00069 0.496
MOD_CK1_1 888 894 PF00069 0.592
MOD_CK2_1 1038 1044 PF00069 0.307
MOD_CK2_1 1220 1226 PF00069 0.521
MOD_CK2_1 1294 1300 PF00069 0.476
MOD_CK2_1 228 234 PF00069 0.376
MOD_CK2_1 254 260 PF00069 0.462
MOD_CK2_1 326 332 PF00069 0.642
MOD_CK2_1 46 52 PF00069 0.365
MOD_CK2_1 587 593 PF00069 0.386
MOD_CK2_1 633 639 PF00069 0.386
MOD_CK2_1 676 682 PF00069 0.392
MOD_CK2_1 826 832 PF00069 0.571
MOD_CK2_1 890 896 PF00069 0.602
MOD_Cter_Amidation 1034 1037 PF01082 0.558
MOD_Cter_Amidation 1091 1094 PF01082 0.727
MOD_DYRK1A_RPxSP_1 302 306 PF00069 0.491
MOD_GlcNHglycan 1014 1017 PF01048 0.596
MOD_GlcNHglycan 1140 1143 PF01048 0.414
MOD_GlcNHglycan 1260 1263 PF01048 0.287
MOD_GlcNHglycan 1409 1412 PF01048 0.276
MOD_GlcNHglycan 177 180 PF01048 0.473
MOD_GlcNHglycan 386 389 PF01048 0.494
MOD_GlcNHglycan 46 49 PF01048 0.472
MOD_GlcNHglycan 495 498 PF01048 0.392
MOD_GlcNHglycan 775 778 PF01048 0.490
MOD_GlcNHglycan 851 855 PF01048 0.564
MOD_GlcNHglycan 887 890 PF01048 0.530
MOD_GlcNHglycan 907 910 PF01048 0.571
MOD_GlcNHglycan 91 94 PF01048 0.508
MOD_GSK3_1 1010 1017 PF00069 0.536
MOD_GSK3_1 108 115 PF00069 0.406
MOD_GSK3_1 1194 1201 PF00069 0.567
MOD_GSK3_1 1220 1227 PF00069 0.487
MOD_GSK3_1 1229 1236 PF00069 0.459
MOD_GSK3_1 1375 1382 PF00069 0.487
MOD_GSK3_1 1410 1417 PF00069 0.547
MOD_GSK3_1 1461 1468 PF00069 0.482
MOD_GSK3_1 148 155 PF00069 0.442
MOD_GSK3_1 160 167 PF00069 0.268
MOD_GSK3_1 230 237 PF00069 0.397
MOD_GSK3_1 238 245 PF00069 0.398
MOD_GSK3_1 274 281 PF00069 0.399
MOD_GSK3_1 384 391 PF00069 0.463
MOD_GSK3_1 532 539 PF00069 0.457
MOD_GSK3_1 694 701 PF00069 0.372
MOD_GSK3_1 750 757 PF00069 0.524
MOD_GSK3_1 801 808 PF00069 0.426
MOD_GSK3_1 826 833 PF00069 0.476
MOD_GSK3_1 85 92 PF00069 0.440
MOD_GSK3_1 888 895 PF00069 0.544
MOD_GSK3_1 978 985 PF00069 0.376
MOD_LATS_1 1251 1257 PF00433 0.476
MOD_LATS_1 1324 1330 PF00433 0.537
MOD_N-GLC_1 1251 1256 PF02516 0.276
MOD_N-GLC_1 1393 1398 PF02516 0.362
MOD_N-GLC_1 1465 1470 PF02516 0.293
MOD_N-GLC_1 147 152 PF02516 0.518
MOD_N-GLC_1 727 732 PF02516 0.385
MOD_N-GLC_1 742 747 PF02516 0.426
MOD_N-GLC_1 978 983 PF02516 0.468
MOD_NEK2_1 1004 1009 PF00069 0.636
MOD_NEK2_1 1051 1056 PF00069 0.513
MOD_NEK2_1 1181 1186 PF00069 0.528
MOD_NEK2_1 1220 1225 PF00069 0.476
MOD_NEK2_1 1280 1285 PF00069 0.476
MOD_NEK2_1 1375 1380 PF00069 0.562
MOD_NEK2_1 140 145 PF00069 0.412
MOD_NEK2_1 1438 1443 PF00069 0.562
MOD_NEK2_1 147 152 PF00069 0.403
MOD_NEK2_1 1508 1513 PF00069 0.482
MOD_NEK2_1 238 243 PF00069 0.419
MOD_NEK2_1 254 259 PF00069 0.452
MOD_NEK2_1 297 302 PF00069 0.428
MOD_NEK2_1 472 477 PF00069 0.365
MOD_NEK2_1 512 517 PF00069 0.424
MOD_NEK2_1 711 716 PF00069 0.591
MOD_NEK2_1 727 732 PF00069 0.258
MOD_NEK2_1 744 749 PF00069 0.328
MOD_NEK2_1 824 829 PF00069 0.418
MOD_NEK2_1 870 875 PF00069 0.237
MOD_NEK2_1 982 987 PF00069 0.311
MOD_NEK2_2 1520 1525 PF00069 0.562
MOD_NEK2_2 166 171 PF00069 0.348
MOD_NEK2_2 259 264 PF00069 0.384
MOD_NEK2_2 610 615 PF00069 0.577
MOD_NEK2_2 762 767 PF00069 0.495
MOD_PIKK_1 1294 1300 PF00454 0.476
MOD_PIKK_1 1373 1379 PF00454 0.495
MOD_PIKK_1 140 146 PF00454 0.496
MOD_PIKK_1 242 248 PF00454 0.451
MOD_PIKK_1 289 295 PF00454 0.511
MOD_PIKK_1 524 530 PF00454 0.584
MOD_PK_1 1206 1212 PF00069 0.400
MOD_PK_1 248 254 PF00069 0.489
MOD_PK_1 826 832 PF00069 0.518
MOD_PKA_1 103 109 PF00069 0.406
MOD_PKA_1 1326 1332 PF00069 0.537
MOD_PKA_1 1462 1468 PF00069 0.562
MOD_PKA_1 825 831 PF00069 0.441
MOD_PKA_2 1009 1015 PF00069 0.555
MOD_PKA_2 103 109 PF00069 0.239
MOD_PKA_2 1181 1187 PF00069 0.537
MOD_PKA_2 1326 1332 PF00069 0.537
MOD_PKA_2 1461 1467 PF00069 0.562
MOD_PKA_2 246 252 PF00069 0.522
MOD_PKA_2 289 295 PF00069 0.451
MOD_PKA_2 334 340 PF00069 0.493
MOD_PKA_2 694 700 PF00069 0.597
MOD_PKA_2 750 756 PF00069 0.460
MOD_PKA_2 762 768 PF00069 0.190
MOD_PKA_2 824 830 PF00069 0.414
MOD_PKB_1 1008 1016 PF00069 0.630
MOD_PKB_1 1180 1188 PF00069 0.562
MOD_Plk_1 1192 1198 PF00069 0.476
MOD_Plk_1 1272 1278 PF00069 0.562
MOD_Plk_1 1294 1300 PF00069 0.476
MOD_Plk_1 1393 1399 PF00069 0.562
MOD_Plk_1 1414 1420 PF00069 0.476
MOD_Plk_1 259 265 PF00069 0.365
MOD_Plk_1 310 316 PF00069 0.417
MOD_Plk_1 472 478 PF00069 0.386
MOD_Plk_1 512 518 PF00069 0.500
MOD_Plk_1 711 717 PF00069 0.546
MOD_Plk_1 742 748 PF00069 0.290
MOD_Plk_1 836 842 PF00069 0.571
MOD_Plk_1 850 856 PF00069 0.561
MOD_Plk_1 923 929 PF00069 0.540
MOD_Plk_1 978 984 PF00069 0.467
MOD_Plk_2-3 1273 1279 PF00069 0.562
MOD_Plk_2-3 311 317 PF00069 0.274
MOD_Plk_2-3 890 896 PF00069 0.590
MOD_Plk_2-3 923 929 PF00069 0.550
MOD_Plk_4 1051 1057 PF00069 0.511
MOD_Plk_4 11 17 PF00069 0.495
MOD_Plk_4 1194 1200 PF00069 0.498
MOD_Plk_4 1206 1212 PF00069 0.449
MOD_Plk_4 1220 1226 PF00069 0.468
MOD_Plk_4 1233 1239 PF00069 0.476
MOD_Plk_4 1326 1332 PF00069 0.537
MOD_Plk_4 152 158 PF00069 0.375
MOD_Plk_4 1520 1526 PF00069 0.539
MOD_Plk_4 1538 1544 PF00069 0.403
MOD_Plk_4 160 166 PF00069 0.379
MOD_Plk_4 234 240 PF00069 0.419
MOD_Plk_4 267 273 PF00069 0.485
MOD_Plk_4 421 427 PF00069 0.570
MOD_Plk_4 536 542 PF00069 0.421
MOD_Plk_4 579 585 PF00069 0.355
MOD_Plk_4 762 768 PF00069 0.389
MOD_Plk_4 826 832 PF00069 0.535
MOD_Plk_4 935 941 PF00069 0.372
MOD_ProDKin_1 1465 1471 PF00069 0.476
MOD_ProDKin_1 192 198 PF00069 0.562
MOD_ProDKin_1 302 308 PF00069 0.493
MOD_ProDKin_1 379 385 PF00069 0.428
MOD_SUMO_for_1 1056 1059 PF00179 0.382
MOD_SUMO_rev_2 1120 1129 PF00179 0.435
MOD_SUMO_rev_2 1201 1208 PF00179 0.400
MOD_SUMO_rev_2 18 23 PF00179 0.454
MOD_SUMO_rev_2 455 461 PF00179 0.508
MOD_SUMO_rev_2 624 629 PF00179 0.417
MOD_SUMO_rev_2 747 756 PF00179 0.487
MOD_SUMO_rev_2 85 93 PF00179 0.501
MOD_SUMO_rev_2 970 976 PF00179 0.496
TRG_DiLeu_BaEn_1 646 651 PF01217 0.394
TRG_DiLeu_BaEn_2 135 141 PF01217 0.424
TRG_DiLeu_BaEn_2 567 573 PF01217 0.343
TRG_DiLeu_BaEn_4 260 266 PF01217 0.512
TRG_ENDOCYTIC_2 1065 1068 PF00928 0.336
TRG_ENDOCYTIC_2 1118 1121 PF00928 0.433
TRG_ENDOCYTIC_2 1143 1146 PF00928 0.395
TRG_ENDOCYTIC_2 1296 1299 PF00928 0.476
TRG_ENDOCYTIC_2 1337 1340 PF00928 0.476
TRG_ENDOCYTIC_2 1397 1400 PF00928 0.487
TRG_ENDOCYTIC_2 1502 1505 PF00928 0.487
TRG_ENDOCYTIC_2 1525 1528 PF00928 0.537
TRG_ENDOCYTIC_2 1547 1550 PF00928 0.487
TRG_ENDOCYTIC_2 236 239 PF00928 0.470
TRG_ENDOCYTIC_2 29 32 PF00928 0.336
TRG_ENDOCYTIC_2 36 39 PF00928 0.332
TRG_ENDOCYTIC_2 467 470 PF00928 0.373
TRG_ENDOCYTIC_2 480 483 PF00928 0.373
TRG_ENDOCYTIC_2 492 495 PF00928 0.379
TRG_ENDOCYTIC_2 548 551 PF00928 0.371
TRG_ENDOCYTIC_2 634 637 PF00928 0.420
TRG_ENDOCYTIC_2 683 686 PF00928 0.441
TRG_ENDOCYTIC_2 994 997 PF00928 0.259
TRG_ER_diArg_1 1108 1111 PF00400 0.447
TRG_ER_diArg_1 1126 1129 PF00400 0.254
TRG_ER_diArg_1 1178 1180 PF00400 0.562
TRG_ER_diArg_1 191 193 PF00400 0.511
TRG_ER_diArg_1 209 211 PF00400 0.222
TRG_ER_diArg_1 288 291 PF00400 0.290
TRG_ER_diArg_1 351 353 PF00400 0.383
TRG_ER_diArg_1 443 445 PF00400 0.541
TRG_ER_diArg_1 464 466 PF00400 0.482
TRG_ER_diArg_1 477 479 PF00400 0.254
TRG_ER_diArg_1 508 510 PF00400 0.489
TRG_ER_diArg_1 569 571 PF00400 0.347
TRG_ER_diArg_1 573 575 PF00400 0.375
TRG_ER_diArg_1 707 709 PF00400 0.610
TRG_ER_diArg_1 834 836 PF00400 0.523
TRG_ER_diArg_1 860 862 PF00400 0.358
TRG_NES_CRM1_1 206 222 PF08389 0.376
TRG_NLS_MonoExtC_3 1089 1094 PF00514 0.591
TRG_NLS_MonoExtN_4 1087 1094 PF00514 0.577
TRG_Pf-PMV_PEXEL_1 1373 1377 PF00026 0.341
TRG_Pf-PMV_PEXEL_1 1387 1391 PF00026 0.207
TRG_Pf-PMV_PEXEL_1 1570 1574 PF00026 0.536
TRG_Pf-PMV_PEXEL_1 256 260 PF00026 0.439
TRG_Pf-PMV_PEXEL_1 403 407 PF00026 0.596
TRG_Pf-PMV_PEXEL_1 445 449 PF00026 0.567
TRG_Pf-PMV_PEXEL_1 466 471 PF00026 0.388
TRG_Pf-PMV_PEXEL_1 658 662 PF00026 0.370
TRG_Pf-PMV_PEXEL_1 709 713 PF00026 0.629

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P566 Leptomonas seymouri 83% 96%
A0A0S4IR82 Bodo saltans 45% 92%
A0A1X0NJI0 Trypanosomatidae 67% 97%
A0A3Q8I9M8 Leishmania donovani 92% 100%
A0A3R7N472 Trypanosoma rangeli 67% 97%
A4HVU1 Leishmania infantum 93% 100%
D0A6E4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 66% 97%
E9API7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4QFZ1 Leishmania major 92% 100%
V5BM10 Trypanosoma cruzi 67% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS