LeishMANIAdb
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Phospholipid-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phospholipid-transporting ATPase
Gene product:
phospholipid-transporting ATPase 1-like protein
Species:
Leishmania braziliensis
UniProt:
A4H7E4_LEIBR
TriTrypDb:
LbrM.13.1400 , LBRM2903_130020300
Length:
1068

Annotations

LeishMANIAdb annotations

Homologous to endosomal / ER-localized phospholipid flippases of other Eukaryotes.. These genes only duplicated in Trypasoma conorini and Trypansoma cruzi. Localization: ER (by homology) / Endosomal (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 6
Silverman et al. no yes: 0
Pissara et al. no yes: 4
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
Term Name Level Count
GO:0016020 membrane 2 14
GO:0110165 cellular anatomical entity 1 14
GO:0005737 cytoplasm 2 1
GO:0005886 plasma membrane 3 1

Expansion

Sequence features

A4H7E4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7E4

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 13
GO:0006869 lipid transport 5 13
GO:0015748 organophosphate ester transport 5 13
GO:0015914 phospholipid transport 6 13
GO:0051179 localization 1 13
GO:0051234 establishment of localization 2 13
GO:0071702 organic substance transport 4 13
GO:0009987 cellular process 1 1
GO:0016043 cellular component organization 3 1
GO:0034204 lipid translocation 4 1
GO:0045332 phospholipid translocation 5 1
GO:0061024 membrane organization 4 1
GO:0065007 biological regulation 1 1
GO:0065008 regulation of biological quality 2 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0097035 regulation of membrane lipid distribution 3 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 14
GO:0000287 magnesium ion binding 5 13
GO:0003824 catalytic activity 1 13
GO:0005215 transporter activity 1 13
GO:0005319 lipid transporter activity 2 13
GO:0005488 binding 1 14
GO:0005524 ATP binding 5 13
GO:0016462 pyrophosphatase activity 5 13
GO:0016787 hydrolase activity 2 13
GO:0016817 hydrolase activity, acting on acid anhydrides 3 13
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 13
GO:0016887 ATP hydrolysis activity 7 13
GO:0017076 purine nucleotide binding 4 13
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 13
GO:0030554 adenyl nucleotide binding 5 13
GO:0032553 ribonucleotide binding 3 13
GO:0032555 purine ribonucleotide binding 4 13
GO:0032559 adenyl ribonucleotide binding 5 13
GO:0035639 purine ribonucleoside triphosphate binding 4 13
GO:0036094 small molecule binding 2 14
GO:0043167 ion binding 2 13
GO:0043168 anion binding 3 13
GO:0043169 cation binding 3 13
GO:0046872 metal ion binding 4 13
GO:0097159 organic cyclic compound binding 2 14
GO:0097367 carbohydrate derivative binding 2 13
GO:0140303 intramembrane lipid transporter activity 3 13
GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2 13
GO:0140657 ATP-dependent activity 1 13
GO:1901265 nucleoside phosphate binding 3 14
GO:1901363 heterocyclic compound binding 2 14

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 553 557 PF00656 0.613
CLV_NRD_NRD_1 173 175 PF00675 0.256
CLV_NRD_NRD_1 267 269 PF00675 0.300
CLV_NRD_NRD_1 423 425 PF00675 0.469
CLV_NRD_NRD_1 514 516 PF00675 0.212
CLV_NRD_NRD_1 714 716 PF00675 0.366
CLV_NRD_NRD_1 816 818 PF00675 0.250
CLV_PCSK_KEX2_1 105 107 PF00082 0.344
CLV_PCSK_KEX2_1 402 404 PF00082 0.313
CLV_PCSK_KEX2_1 654 656 PF00082 0.336
CLV_PCSK_KEX2_1 714 716 PF00082 0.350
CLV_PCSK_KEX2_1 816 818 PF00082 0.250
CLV_PCSK_KEX2_1 99 101 PF00082 0.360
CLV_PCSK_PC1ET2_1 105 107 PF00082 0.434
CLV_PCSK_PC1ET2_1 402 404 PF00082 0.313
CLV_PCSK_PC1ET2_1 654 656 PF00082 0.336
CLV_PCSK_PC1ET2_1 99 101 PF00082 0.442
CLV_PCSK_SKI1_1 1046 1050 PF00082 0.281
CLV_PCSK_SKI1_1 254 258 PF00082 0.283
CLV_PCSK_SKI1_1 259 263 PF00082 0.284
CLV_PCSK_SKI1_1 321 325 PF00082 0.360
CLV_PCSK_SKI1_1 384 388 PF00082 0.275
CLV_PCSK_SKI1_1 489 493 PF00082 0.297
CLV_PCSK_SKI1_1 528 532 PF00082 0.277
CLV_PCSK_SKI1_1 571 575 PF00082 0.297
CLV_PCSK_SKI1_1 578 582 PF00082 0.306
CLV_PCSK_SKI1_1 840 844 PF00082 0.421
CLV_PCSK_SKI1_1 918 922 PF00082 0.370
CLV_PCSK_SKI1_1 968 972 PF00082 0.394
DEG_Nend_UBRbox_2 1 3 PF02207 0.537
DEG_SPOP_SBC_1 662 666 PF00917 0.549
DOC_CDC14_PxL_1 64 72 PF14671 0.370
DOC_CDC14_PxL_1 932 940 PF14671 0.458
DOC_CKS1_1 901 906 PF01111 0.542
DOC_CYCLIN_yClb5_NLxxxL_5 261 270 PF00134 0.542
DOC_MAPK_FxFP_2 24 27 PF00069 0.542
DOC_MAPK_gen_1 268 275 PF00069 0.419
DOC_MAPK_gen_1 298 307 PF00069 0.563
DOC_MAPK_gen_1 400 409 PF00069 0.570
DOC_MAPK_gen_1 486 495 PF00069 0.459
DOC_MAPK_gen_1 51 58 PF00069 0.565
DOC_MAPK_gen_1 515 522 PF00069 0.446
DOC_MAPK_gen_1 654 661 PF00069 0.530
DOC_MAPK_gen_1 714 720 PF00069 0.595
DOC_MAPK_HePTP_8 483 495 PF00069 0.446
DOC_MAPK_MEF2A_6 1022 1029 PF00069 0.300
DOC_MAPK_MEF2A_6 268 277 PF00069 0.392
DOC_MAPK_MEF2A_6 298 307 PF00069 0.545
DOC_MAPK_MEF2A_6 402 411 PF00069 0.490
DOC_MAPK_MEF2A_6 486 495 PF00069 0.446
DOC_MAPK_MEF2A_6 515 522 PF00069 0.456
DOC_MAPK_MEF2A_6 829 838 PF00069 0.481
DOC_MAPK_NFAT4_5 1022 1030 PF00069 0.313
DOC_PP1_RVXF_1 1044 1050 PF00149 0.408
DOC_PP2B_LxvP_1 407 410 PF13499 0.510
DOC_PP4_FxxP_1 24 27 PF00568 0.541
DOC_USP7_MATH_1 1004 1008 PF00917 0.325
DOC_USP7_MATH_1 260 264 PF00917 0.482
DOC_USP7_MATH_1 371 375 PF00917 0.516
DOC_USP7_MATH_1 410 414 PF00917 0.483
DOC_USP7_MATH_1 595 599 PF00917 0.660
DOC_USP7_MATH_1 662 666 PF00917 0.536
DOC_USP7_MATH_1 75 79 PF00917 0.424
DOC_WW_Pin1_4 463 468 PF00397 0.461
DOC_WW_Pin1_4 509 514 PF00397 0.456
DOC_WW_Pin1_4 68 73 PF00397 0.297
DOC_WW_Pin1_4 681 686 PF00397 0.534
DOC_WW_Pin1_4 749 754 PF00397 0.512
DOC_WW_Pin1_4 900 905 PF00397 0.512
LIG_14-3-3_CanoR_1 234 242 PF00244 0.467
LIG_14-3-3_CanoR_1 321 326 PF00244 0.532
LIG_14-3-3_CanoR_1 384 394 PF00244 0.492
LIG_14-3-3_CanoR_1 482 486 PF00244 0.410
LIG_14-3-3_CanoR_1 602 607 PF00244 0.597
LIG_14-3-3_CanoR_1 714 719 PF00244 0.516
LIG_14-3-3_CanoR_1 824 828 PF00244 0.472
LIG_14-3-3_CanoR_1 829 838 PF00244 0.474
LIG_Actin_WH2_2 220 236 PF00022 0.456
LIG_Actin_WH2_2 249 264 PF00022 0.408
LIG_Actin_WH2_2 694 710 PF00022 0.643
LIG_Actin_WH2_2 722 740 PF00022 0.584
LIG_AP2alpha_2 586 588 PF02296 0.603
LIG_APCC_ABBA_1 448 453 PF00400 0.526
LIG_BRCT_BRCA1_1 1006 1010 PF00533 0.271
LIG_CSL_BTD_1 72 75 PF09270 0.208
LIG_deltaCOP1_diTrp_1 237 240 PF00928 0.467
LIG_deltaCOP1_diTrp_1 586 592 PF00928 0.529
LIG_deltaCOP1_diTrp_1 864 870 PF00928 0.267
LIG_EH1_1 271 279 PF00400 0.563
LIG_EH1_1 57 65 PF00400 0.313
LIG_eIF4E_1 1023 1029 PF01652 0.377
LIG_eIF4E_1 1030 1036 PF01652 0.314
LIG_FHA_1 1036 1042 PF00498 0.435
LIG_FHA_1 160 166 PF00498 0.455
LIG_FHA_1 178 184 PF00498 0.398
LIG_FHA_1 191 197 PF00498 0.456
LIG_FHA_1 207 213 PF00498 0.385
LIG_FHA_1 234 240 PF00498 0.461
LIG_FHA_1 322 328 PF00498 0.443
LIG_FHA_1 338 344 PF00498 0.513
LIG_FHA_1 371 377 PF00498 0.501
LIG_FHA_1 389 395 PF00498 0.478
LIG_FHA_1 486 492 PF00498 0.483
LIG_FHA_1 497 503 PF00498 0.451
LIG_FHA_1 525 531 PF00498 0.517
LIG_FHA_1 570 576 PF00498 0.493
LIG_FHA_1 641 647 PF00498 0.488
LIG_FHA_1 662 668 PF00498 0.504
LIG_FHA_1 715 721 PF00498 0.496
LIG_FHA_1 75 81 PF00498 0.253
LIG_FHA_1 769 775 PF00498 0.443
LIG_FHA_1 841 847 PF00498 0.458
LIG_FHA_1 85 91 PF00498 0.253
LIG_FHA_1 919 925 PF00498 0.374
LIG_FHA_2 1049 1055 PF00498 0.526
LIG_FHA_2 149 155 PF00498 0.500
LIG_FHA_2 391 397 PF00498 0.491
LIG_FHA_2 463 469 PF00498 0.449
LIG_FHA_2 559 565 PF00498 0.512
LIG_FHA_2 621 627 PF00498 0.502
LIG_FHA_2 664 670 PF00498 0.579
LIG_FHA_2 708 714 PF00498 0.691
LIG_FHA_2 859 865 PF00498 0.281
LIG_HCF-1_HBM_1 301 304 PF13415 0.408
LIG_LIR_Apic_2 330 334 PF02991 0.468
LIG_LIR_Apic_2 806 810 PF02991 0.457
LIG_LIR_Gen_1 1009 1018 PF02991 0.266
LIG_LIR_Gen_1 301 311 PF02991 0.542
LIG_LIR_Gen_1 324 334 PF02991 0.479
LIG_LIR_Gen_1 33 44 PF02991 0.432
LIG_LIR_Gen_1 336 346 PF02991 0.493
LIG_LIR_Gen_1 437 444 PF02991 0.493
LIG_LIR_Gen_1 730 739 PF02991 0.512
LIG_LIR_Gen_1 909 917 PF02991 0.494
LIG_LIR_LC3C_4 1032 1037 PF02991 0.241
LIG_LIR_Nem_3 1007 1013 PF02991 0.246
LIG_LIR_Nem_3 1020 1026 PF02991 0.297
LIG_LIR_Nem_3 207 211 PF02991 0.545
LIG_LIR_Nem_3 237 243 PF02991 0.456
LIG_LIR_Nem_3 250 256 PF02991 0.426
LIG_LIR_Nem_3 301 307 PF02991 0.498
LIG_LIR_Nem_3 324 329 PF02991 0.491
LIG_LIR_Nem_3 33 39 PF02991 0.450
LIG_LIR_Nem_3 336 341 PF02991 0.507
LIG_LIR_Nem_3 40 44 PF02991 0.441
LIG_LIR_Nem_3 437 442 PF02991 0.484
LIG_LIR_Nem_3 455 461 PF02991 0.605
LIG_LIR_Nem_3 54 60 PF02991 0.309
LIG_LIR_Nem_3 730 736 PF02991 0.507
LIG_LIR_Nem_3 837 842 PF02991 0.238
LIG_LIR_Nem_3 855 860 PF02991 0.336
LIG_LIR_Nem_3 909 914 PF02991 0.512
LIG_LIR_Nem_3 955 961 PF02991 0.397
LIG_LYPXL_yS_3 935 938 PF13949 0.342
LIG_MLH1_MIPbox_1 1008 1012 PF16413 0.300
LIG_MYND_1 68 72 PF01753 0.370
LIG_NRBOX 569 575 PF00104 0.511
LIG_NRBOX 912 918 PF00104 0.562
LIG_NRBOX 989 995 PF00104 0.445
LIG_PCNA_yPIPBox_3 379 390 PF02747 0.489
LIG_Pex14_1 318 322 PF04695 0.505
LIG_Pex14_1 588 592 PF04695 0.527
LIG_Pex14_1 866 870 PF04695 0.324
LIG_Pex14_2 1044 1048 PF04695 0.550
LIG_Pex14_2 849 853 PF04695 0.365
LIG_Pex14_2 870 874 PF04695 0.363
LIG_Pex14_2 882 886 PF04695 0.296
LIG_PTB_Apo_2 52 59 PF02174 0.295
LIG_SH2_CRK 320 324 PF00017 0.553
LIG_SH2_CRK 331 335 PF00017 0.543
LIG_SH2_CRK 36 40 PF00017 0.484
LIG_SH2_CRK 503 507 PF00017 0.497
LIG_SH2_CRK 807 811 PF00017 0.466
LIG_SH2_CRK 839 843 PF00017 0.293
LIG_SH2_CRK 902 906 PF00017 0.563
LIG_SH2_CRK 998 1002 PF00017 0.366
LIG_SH2_GRB2like 14 17 PF00017 0.542
LIG_SH2_GRB2like 361 364 PF00017 0.577
LIG_SH2_GRB2like 910 913 PF00017 0.481
LIG_SH2_NCK_1 36 40 PF00017 0.533
LIG_SH2_NCK_1 998 1002 PF00017 0.394
LIG_SH2_SRC 272 275 PF00017 0.500
LIG_SH2_SRC 807 810 PF00017 0.456
LIG_SH2_STAT3 1060 1063 PF00017 0.617
LIG_SH2_STAT3 732 735 PF00017 0.618
LIG_SH2_STAT5 1011 1014 PF00017 0.248
LIG_SH2_STAT5 1026 1029 PF00017 0.349
LIG_SH2_STAT5 1030 1033 PF00017 0.380
LIG_SH2_STAT5 135 138 PF00017 0.542
LIG_SH2_STAT5 272 275 PF00017 0.542
LIG_SH2_STAT5 304 307 PF00017 0.455
LIG_SH2_STAT5 322 325 PF00017 0.427
LIG_SH2_STAT5 331 334 PF00017 0.471
LIG_SH2_STAT5 36 39 PF00017 0.443
LIG_SH2_STAT5 438 441 PF00017 0.487
LIG_SH2_STAT5 57 60 PF00017 0.309
LIG_SH2_STAT5 732 735 PF00017 0.573
LIG_SH2_STAT5 854 857 PF00017 0.371
LIG_SH2_STAT5 902 905 PF00017 0.487
LIG_SH2_STAT5 910 913 PF00017 0.433
LIG_SH2_STAT5 932 935 PF00017 0.296
LIG_SH3_3 682 688 PF00018 0.653
LIG_SH3_3 69 75 PF00018 0.295
LIG_SH3_3 930 936 PF00018 0.277
LIG_SUMO_SIM_anti_2 468 475 PF11976 0.443
LIG_SUMO_SIM_anti_2 490 495 PF11976 0.560
LIG_SUMO_SIM_anti_2 697 702 PF11976 0.601
LIG_SUMO_SIM_anti_2 843 848 PF11976 0.408
LIG_SUMO_SIM_anti_2 87 93 PF11976 0.348
LIG_SUMO_SIM_anti_2 959 965 PF11976 0.458
LIG_SUMO_SIM_par_1 119 125 PF11976 0.521
LIG_SUMO_SIM_par_1 716 721 PF11976 0.532
LIG_SUMO_SIM_par_1 770 776 PF11976 0.440
LIG_SUMO_SIM_par_1 81 87 PF11976 0.241
LIG_SUMO_SIM_par_1 993 999 PF11976 0.324
LIG_TRAF2_1 152 155 PF00917 0.510
LIG_TRAF2_1 710 713 PF00917 0.641
LIG_TRFH_1 998 1002 PF08558 0.241
LIG_TYR_ITIM 243 248 PF00017 0.343
LIG_TYR_ITIM 270 275 PF00017 0.429
LIG_TYR_ITIM 323 328 PF00017 0.340
LIG_TYR_ITIM 933 938 PF00017 0.322
LIG_TYR_ITIM 996 1001 PF00017 0.429
LIG_UBA3_1 252 259 PF00899 0.295
LIG_UBA3_1 305 313 PF00899 0.241
LIG_UBA3_1 337 345 PF00899 0.352
LIG_WRC_WIRS_1 38 43 PF05994 0.283
LIG_WRC_WIRS_1 63 68 PF05994 0.241
LIG_WRC_WIRS_1 835 840 PF05994 0.338
MOD_CDK_SPxK_1 509 515 PF00069 0.309
MOD_CDK_SPxxK_3 509 516 PF00069 0.309
MOD_CDK_SPxxK_3 749 756 PF00069 0.375
MOD_CDK_SPxxK_3 900 907 PF00069 0.241
MOD_CK1_1 122 128 PF00069 0.431
MOD_CK1_1 170 176 PF00069 0.340
MOD_CK1_1 34 40 PF00069 0.366
MOD_CK1_1 543 549 PF00069 0.450
MOD_CK1_1 71 77 PF00069 0.318
MOD_CK1_1 858 864 PF00069 0.327
MOD_CK1_1 923 929 PF00069 0.433
MOD_CK2_1 148 154 PF00069 0.332
MOD_CK2_1 390 396 PF00069 0.359
MOD_CK2_1 463 469 PF00069 0.295
MOD_CK2_1 558 564 PF00069 0.570
MOD_CK2_1 620 626 PF00069 0.368
MOD_CK2_1 707 713 PF00069 0.577
MOD_CK2_1 903 909 PF00069 0.429
MOD_GlcNHglycan 1002 1005 PF01048 0.382
MOD_GlcNHglycan 1031 1034 PF01048 0.429
MOD_GlcNHglycan 744 747 PF01048 0.333
MOD_GlcNHglycan 77 80 PF01048 0.174
MOD_GlcNHglycan 857 860 PF01048 0.346
MOD_GlcNHglycan 958 961 PF01048 0.410
MOD_GlcNHglycan 986 989 PF01048 0.315
MOD_GSK3_1 166 173 PF00069 0.340
MOD_GSK3_1 185 192 PF00069 0.265
MOD_GSK3_1 30 37 PF00069 0.295
MOD_GSK3_1 333 340 PF00069 0.336
MOD_GSK3_1 388 395 PF00069 0.336
MOD_GSK3_1 481 488 PF00069 0.350
MOD_GSK3_1 505 512 PF00069 0.277
MOD_GSK3_1 524 531 PF00069 0.309
MOD_GSK3_1 536 543 PF00069 0.303
MOD_GSK3_1 635 642 PF00069 0.421
MOD_GSK3_1 657 664 PF00069 0.403
MOD_GSK3_1 71 78 PF00069 0.455
MOD_GSK3_1 763 770 PF00069 0.430
MOD_GSK3_1 918 925 PF00069 0.408
MOD_GSK3_1 952 959 PF00069 0.323
MOD_GSK3_1 996 1003 PF00069 0.400
MOD_LATS_1 600 606 PF00433 0.396
MOD_N-GLC_1 190 195 PF02516 0.455
MOD_N-GLC_1 371 376 PF02516 0.383
MOD_N-GLC_1 496 501 PF02516 0.436
MOD_N-GLC_1 590 595 PF02516 0.509
MOD_N-GLC_1 600 605 PF02516 0.512
MOD_N-GLC_1 829 834 PF02516 0.366
MOD_N-GLC_1 840 845 PF02516 0.366
MOD_NEK2_1 1017 1022 PF00069 0.380
MOD_NEK2_1 1029 1034 PF00069 0.312
MOD_NEK2_1 1035 1040 PF00069 0.227
MOD_NEK2_1 148 153 PF00069 0.293
MOD_NEK2_1 159 164 PF00069 0.310
MOD_NEK2_1 190 195 PF00069 0.360
MOD_NEK2_1 196 201 PF00069 0.318
MOD_NEK2_1 206 211 PF00069 0.194
MOD_NEK2_1 261 266 PF00069 0.366
MOD_NEK2_1 30 35 PF00069 0.324
MOD_NEK2_1 416 421 PF00069 0.550
MOD_NEK2_1 444 449 PF00069 0.352
MOD_NEK2_1 472 477 PF00069 0.343
MOD_NEK2_1 540 545 PF00069 0.356
MOD_NEK2_1 62 67 PF00069 0.324
MOD_NEK2_1 639 644 PF00069 0.415
MOD_NEK2_1 707 712 PF00069 0.633
MOD_NEK2_1 737 742 PF00069 0.401
MOD_NEK2_1 763 768 PF00069 0.420
MOD_NEK2_1 796 801 PF00069 0.392
MOD_NEK2_1 874 879 PF00069 0.366
MOD_NEK2_1 920 925 PF00069 0.402
MOD_NEK2_2 1006 1011 PF00069 0.256
MOD_NEK2_2 167 172 PF00069 0.236
MOD_NEK2_2 595 600 PF00069 0.584
MOD_NEK2_2 823 828 PF00069 0.429
MOD_PIKK_1 496 502 PF00454 0.241
MOD_PIKK_1 540 546 PF00454 0.359
MOD_PIKK_1 737 743 PF00454 0.330
MOD_PIKK_1 796 802 PF00454 0.384
MOD_PK_1 106 112 PF00069 0.434
MOD_PK_1 516 522 PF00069 0.309
MOD_PKA_1 51 57 PF00069 0.324
MOD_PKA_1 528 534 PF00069 0.424
MOD_PKA_1 654 660 PF00069 0.402
MOD_PKA_1 714 720 PF00069 0.433
MOD_PKA_2 233 239 PF00069 0.320
MOD_PKA_2 481 487 PF00069 0.302
MOD_PKA_2 601 607 PF00069 0.535
MOD_PKA_2 654 660 PF00069 0.402
MOD_PKA_2 714 720 PF00069 0.386
MOD_PKA_2 737 743 PF00069 0.447
MOD_PKA_2 764 770 PF00069 0.334
MOD_PKA_2 823 829 PF00069 0.324
MOD_Plk_1 167 173 PF00069 0.265
MOD_Plk_1 177 183 PF00069 0.318
MOD_Plk_1 190 196 PF00069 0.411
MOD_Plk_1 416 422 PF00069 0.466
MOD_Plk_1 558 564 PF00069 0.455
MOD_Plk_1 779 785 PF00069 0.383
MOD_Plk_1 829 835 PF00069 0.366
MOD_Plk_1 840 846 PF00069 0.366
MOD_Plk_2-3 161 167 PF00069 0.370
MOD_Plk_4 1006 1012 PF00069 0.291
MOD_Plk_4 185 191 PF00069 0.387
MOD_Plk_4 321 327 PF00069 0.357
MOD_Plk_4 34 40 PF00069 0.294
MOD_Plk_4 516 522 PF00069 0.309
MOD_Plk_4 536 542 PF00069 0.125
MOD_Plk_4 563 569 PF00069 0.460
MOD_Plk_4 635 641 PF00069 0.394
MOD_Plk_4 714 720 PF00069 0.362
MOD_Plk_4 758 764 PF00069 0.489
MOD_Plk_4 779 785 PF00069 0.383
MOD_Plk_4 823 829 PF00069 0.317
MOD_Plk_4 834 840 PF00069 0.293
MOD_Plk_4 842 848 PF00069 0.223
MOD_Plk_4 858 864 PF00069 0.240
MOD_Plk_4 912 918 PF00069 0.394
MOD_Plk_4 934 940 PF00069 0.344
MOD_Plk_4 952 958 PF00069 0.153
MOD_Plk_4 996 1002 PF00069 0.344
MOD_ProDKin_1 463 469 PF00069 0.316
MOD_ProDKin_1 509 515 PF00069 0.309
MOD_ProDKin_1 68 74 PF00069 0.297
MOD_ProDKin_1 681 687 PF00069 0.411
MOD_ProDKin_1 749 755 PF00069 0.382
MOD_ProDKin_1 900 906 PF00069 0.387
MOD_SUMO_rev_2 263 270 PF00179 0.323
MOD_SUMO_rev_2 426 432 PF00179 0.657
MOD_SUMO_rev_2 510 518 PF00179 0.324
MOD_SUMO_rev_2 523 530 PF00179 0.309
MOD_SUMO_rev_2 684 691 PF00179 0.508
TRG_DiLeu_BaEn_1 909 914 PF01217 0.408
TRG_DiLeu_BaEn_3 154 160 PF01217 0.394
TRG_DiLeu_BaEn_4 427 433 PF01217 0.426
TRG_DiLeu_BaLyEn_6 78 83 PF01217 0.370
TRG_ENDOCYTIC_2 1026 1029 PF00928 0.317
TRG_ENDOCYTIC_2 245 248 PF00928 0.324
TRG_ENDOCYTIC_2 272 275 PF00928 0.429
TRG_ENDOCYTIC_2 304 307 PF00928 0.421
TRG_ENDOCYTIC_2 320 323 PF00928 0.265
TRG_ENDOCYTIC_2 325 328 PF00928 0.317
TRG_ENDOCYTIC_2 36 39 PF00928 0.324
TRG_ENDOCYTIC_2 503 506 PF00928 0.324
TRG_ENDOCYTIC_2 57 60 PF00928 0.309
TRG_ENDOCYTIC_2 825 828 PF00928 0.319
TRG_ENDOCYTIC_2 839 842 PF00928 0.280
TRG_ENDOCYTIC_2 854 857 PF00928 0.381
TRG_ENDOCYTIC_2 871 874 PF00928 0.309
TRG_ENDOCYTIC_2 902 905 PF00928 0.356
TRG_ENDOCYTIC_2 910 913 PF00928 0.287
TRG_ENDOCYTIC_2 935 938 PF00928 0.352
TRG_ENDOCYTIC_2 998 1001 PF00928 0.344
TRG_ER_diArg_1 815 817 PF00400 0.300
TRG_Pf-PMV_PEXEL_1 254 258 PF00026 0.313
TRG_Pf-PMV_PEXEL_1 888 892 PF00026 0.394
TRG_Pf-PMV_PEXEL_1 918 922 PF00026 0.370

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P450 Leptomonas seymouri 30% 90%
A0A0N1I0X4 Leptomonas seymouri 72% 97%
A0A0N1PF54 Leptomonas seymouri 27% 82%
A0A0S4IM76 Bodo saltans 29% 100%
A0A0S4J0T6 Bodo saltans 31% 83%
A0A0S4JDQ9 Bodo saltans 38% 95%
A0A0S4JP22 Bodo saltans 33% 86%
A0A0S4JUG6 Bodo saltans 55% 99%
A0A1X0NJY2 Trypanosomatidae 60% 97%
A0A1X0PAR5 Trypanosomatidae 30% 99%
A0A3Q8IFQ5 Leishmania donovani 27% 84%
A0A3Q8INM6 Leishmania donovani 30% 92%
A0A3R7P4C4 Trypanosoma rangeli 54% 99%
A0A3S5IS27 Trypanosoma rangeli 28% 88%
A0A422NNI9 Trypanosoma rangeli 30% 99%
A1A4J6 Bos taurus 32% 94%
A3FIN4 Mus musculus 33% 90%
A4H7E2 Leishmania braziliensis 98% 100%
A4HIF8 Leishmania braziliensis 28% 86%
A4HVT2 Leishmania infantum 81% 97%
A4I5Q4 Leishmania infantum 27% 84%
A4IA89 Leishmania infantum 30% 92%
C7EXK4 Bos taurus 35% 93%
C9ZM06 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 99%
C9ZR23 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 89%
D0A6F9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 95%
D4AA47 Rattus norvegicus 32% 85%
D4ABB8 Rattus norvegicus 30% 93%
E9APH7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 97%
E9B0Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 84%
E9B5B1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 92%
F1Q4S1 Danio rerio 31% 95%
G5EBH1 Caenorhabditis elegans 32% 99%
O36028 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 78%
O43520 Homo sapiens 32% 85%
O43861 Homo sapiens 31% 93%
O60423 Homo sapiens 29% 82%
O70228 Mus musculus 30% 100%
O75110 Homo sapiens 30% 100%
O94296 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 34% 85%
P32660 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 68%
P39524 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 33% 79%
P40527 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 93%
P54209 Dunaliella bioculata 24% 100%
P57792 Arabidopsis thaliana 33% 90%
P70704 Mus musculus 34% 92%
P98195 Mus musculus 31% 93%
P98196 Homo sapiens 31% 94%
P98197 Mus musculus 30% 90%
P98198 Homo sapiens 33% 88%
P98199 Mus musculus 33% 88%
P98200 Mus musculus 34% 93%
P98204 Arabidopsis thaliana 32% 92%
P98205 Arabidopsis thaliana 33% 96%
Q09891 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 76%
Q10309 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
Q12675 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 31% 66%
Q148W0 Mus musculus 32% 85%
Q29449 Bos taurus 34% 93%
Q4Q2M2 Leishmania major 30% 100%
Q4Q767 Leishmania major 28% 84%
Q4QG01 Leishmania major 80% 100%
Q5BL50 Xenopus tropicalis 31% 85%
Q6DFW5 Mus musculus 32% 91%
Q6UQ17 Mus musculus 31% 80%
Q6VXY9 Leishmania donovani 81% 97%
Q8NB49 Homo sapiens 31% 94%
Q8TF62 Homo sapiens 32% 90%
Q95JN5 Macaca fascicularis 21% 87%
Q9H7F0 Homo sapiens 21% 87%
Q9LI83 Arabidopsis thaliana 33% 89%
Q9LK90 Arabidopsis thaliana 33% 90%
Q9LNQ4 Arabidopsis thaliana 32% 88%
Q9N0Z4 Oryctolagus cuniculus 31% 91%
Q9NTI2 Homo sapiens 35% 90%
Q9QZW0 Mus musculus 32% 95%
Q9SAF5 Arabidopsis thaliana 32% 89%
Q9SGG3 Arabidopsis thaliana 32% 87%
Q9SX33 Arabidopsis thaliana 33% 89%
Q9U280 Caenorhabditis elegans 34% 94%
Q9XIE6 Arabidopsis thaliana 33% 88%
Q9Y2G3 Homo sapiens 32% 91%
Q9Y2Q0 Homo sapiens 34% 92%
V5BHI7 Trypanosoma cruzi 57% 100%
V5BV40 Trypanosoma cruzi 30% 99%
V5DCY9 Trypanosoma cruzi 30% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS