Movement protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Movement protein

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H7A8_LEIBR

TriTrypDb:

LbrM.13.1020 , LBRM2903_130016600

Length:

145

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

Expansion

Sequence features

A4H7A8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7A8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	72	76	PF00656	0.401
CLV_NRD_NRD_1	118	120	PF00675	0.709
CLV_PCSK_KEX2_1	104	106	PF00082	0.704
CLV_PCSK_KEX2_1	67	69	PF00082	0.676
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.704
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.659
CLV_PCSK_PC7_1	63	69	PF00082	0.671
CLV_PCSK_SKI1_1	67	71	PF00082	0.673
DEG_APCC_DBOX_1	122	130	PF00400	0.419
DOC_CKS1_1	10	15	PF01111	0.675
DOC_CKS1_1	62	67	PF01111	0.459
DOC_CYCLIN_RxL_1	63	72	PF00134	0.552
DOC_MAPK_gen_1	119	128	PF00069	0.424
DOC_MAPK_HePTP_8	116	128	PF00069	0.425
DOC_MAPK_MEF2A_6	119	128	PF00069	0.424
DOC_PP2B_LxvP_1	129	132	PF13499	0.413
DOC_USP7_MATH_1	130	134	PF00917	0.435
DOC_WW_Pin1_4	138	143	PF00397	0.425
DOC_WW_Pin1_4	61	66	PF00397	0.449
DOC_WW_Pin1_4	9	14	PF00397	0.677
LIG_14-3-3_CanoR_1	119	126	PF00244	0.518
LIG_BIR_II_1	1	5	PF00653	0.669
LIG_Clathr_ClatBox_1	39	43	PF01394	0.507
LIG_deltaCOP1_diTrp_1	28	37	PF00928	0.522
LIG_FHA_1	123	129	PF00498	0.590
LIG_FHA_1	16	22	PF00498	0.758
LIG_LIR_Nem_3	33	39	PF02991	0.442
LIG_SH2_STAT5	58	61	PF00017	0.512
LIG_SH2_STAT5	97	100	PF00017	0.497
LIG_SH3_2	17	22	PF14604	0.587
LIG_SH3_3	14	20	PF00018	0.674
LIG_SH3_3	59	65	PF00018	0.544
LIG_SUMO_SIM_anti_2	125	130	PF11976	0.418
LIG_SUMO_SIM_par_1	37	43	PF11976	0.496
MOD_CDK_SPK_2	138	143	PF00069	0.406
MOD_CDK_SPxK_1	61	67	PF00069	0.455
MOD_CDK_SPxxK_3	61	68	PF00069	0.459
MOD_CK1_1	133	139	PF00069	0.455
MOD_CK1_1	27	33	PF00069	0.661
MOD_CK1_1	84	90	PF00069	0.521
MOD_CK1_1	99	105	PF00069	0.492
MOD_CK2_1	27	33	PF00069	0.539
MOD_CK2_1	88	94	PF00069	0.577
MOD_Cter_Amidation	117	120	PF01082	0.629
MOD_Cter_Amidation	65	68	PF01082	0.676
MOD_GlcNHglycan	1	4	PF01048	0.465
MOD_GSK3_1	118	125	PF00069	0.572
MOD_GSK3_1	4	11	PF00069	0.586
MOD_GSK3_1	77	84	PF00069	0.512
MOD_GSK3_1	85	92	PF00069	0.355
MOD_GSK3_1	93	100	PF00069	0.460
MOD_PIKK_1	130	136	PF00454	0.500
MOD_PKA_2	118	124	PF00069	0.519
MOD_Plk_1	27	33	PF00069	0.539
MOD_Plk_1	93	99	PF00069	0.408
MOD_Plk_4	93	99	PF00069	0.408
MOD_ProDKin_1	138	144	PF00069	0.426
MOD_ProDKin_1	61	67	PF00069	0.455
MOD_ProDKin_1	9	15	PF00069	0.676
TRG_DiLeu_BaLyEn_6	65	70	PF01217	0.555
TRG_ENDOCYTIC_2	57	60	PF00928	0.412
TRG_Pf-PMV_PEXEL_1	68	72	PF00026	0.760

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P887	Leptomonas seymouri	47%	100%
A0A3S5H6P6	Leishmania donovani	67%	97%
A4HVQ3	Leishmania infantum	67%	97%
Q4QG29	Leishmania major	67%	100%