39S ribosomal protein L16, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H7A4_LEIBR

TriTrypDb:

LbrM.13.0980 , LBRM2903_130016100

Length:

185

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H7A4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H7A4

PDB structure(s): 7aih_P , 7ane_P

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	26	28	PF00675	0.410
CLV_NRD_NRD_1	51	53	PF00675	0.480
CLV_PCSK_KEX2_1	26	28	PF00082	0.430
CLV_PCSK_KEX2_1	50	52	PF00082	0.456
CLV_PCSK_SKI1_1	117	121	PF00082	0.408
CLV_PCSK_SKI1_1	27	31	PF00082	0.390
DEG_APCC_DBOX_1	136	144	PF00400	0.510
DEG_Nend_Nbox_1	1	3	PF02207	0.535
DOC_CKS1_1	36	41	PF01111	0.385
DOC_CYCLIN_yCln2_LP_2	172	178	PF00134	0.303
DOC_MAPK_gen_1	123	130	PF00069	0.468
DOC_PP4_FxxP_1	162	165	PF00568	0.401
DOC_WW_Pin1_4	2	7	PF00397	0.604
DOC_WW_Pin1_4	21	26	PF00397	0.429
DOC_WW_Pin1_4	35	40	PF00397	0.335
LIG_14-3-3_CanoR_1	123	129	PF00244	0.439
LIG_14-3-3_CanoR_1	181	185	PF00244	0.480
LIG_FHA_1	167	173	PF00498	0.456
LIG_FHA_1	81	87	PF00498	0.345
LIG_FHA_1	89	95	PF00498	0.354
LIG_FHA_2	39	45	PF00498	0.428
LIG_LIR_Apic_2	159	165	PF02991	0.406
LIG_LIR_Gen_1	97	107	PF02991	0.469
LIG_LIR_Nem_3	76	80	PF02991	0.361
LIG_LIR_Nem_3	97	103	PF02991	0.464
LIG_MYND_1	174	178	PF01753	0.499
LIG_PTB_Apo_2	92	99	PF02174	0.388
LIG_PTB_Phospho_1	92	98	PF10480	0.390
LIG_SH2_STAT3	58	61	PF00017	0.587
LIG_SH3_3	140	146	PF00018	0.508
LIG_SH3_3	33	39	PF00018	0.397
MOD_CDC14_SPxK_1	24	27	PF00782	0.478
MOD_CDK_SPK_2	21	26	PF00069	0.565
MOD_CDK_SPxK_1	21	27	PF00069	0.503
MOD_CDK_SPxxK_3	21	28	PF00069	0.544
MOD_CDK_SPxxK_3	38	45	PF00069	0.324
MOD_CK1_1	11	17	PF00069	0.522
MOD_CK1_1	156	162	PF00069	0.334
MOD_CK2_1	38	44	PF00069	0.401
MOD_GSK3_1	4	11	PF00069	0.542
MOD_GSK3_1	75	82	PF00069	0.409
MOD_GSK3_1	85	92	PF00069	0.389
MOD_NEK2_1	153	158	PF00069	0.346
MOD_NEK2_1	79	84	PF00069	0.393
MOD_NEK2_2	85	90	PF00069	0.355
MOD_PKA_2	56	62	PF00069	0.500
MOD_PKA_2	89	95	PF00069	0.373
MOD_Plk_4	124	130	PF00069	0.462
MOD_ProDKin_1	2	8	PF00069	0.605
MOD_ProDKin_1	21	27	PF00069	0.424
MOD_ProDKin_1	35	41	PF00069	0.338
TRG_ENDOCYTIC_2	98	101	PF00928	0.337
TRG_ER_diArg_1	111	114	PF00400	0.422
TRG_ER_diArg_1	25	27	PF00400	0.436
TRG_ER_diArg_1	50	52	PF00400	0.432
TRG_NLS_MonoExtN_4	25	31	PF00514	0.389

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMF0	Leptomonas seymouri	83%	100%
A0A0S4JV89	Bodo saltans	61%	100%
A0A1X0NMX1	Trypanosomatidae	74%	100%
A0A3S7WSK9	Leishmania donovani	92%	100%
A0A422NLH3	Trypanosoma rangeli	73%	100%
A4HVP8	Leishmania infantum	92%	100%
E9APE4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QG34	Leishmania major	92%	100%