Glycosyltransferase family-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

glycosyltransferase family-like protein

Species:

Leishmania braziliensis

UniProt:

A4H781_LEIBR

TriTrypDb:

LbrM.13.0740 , LBRM2903_130013200

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 21
NetGPI	no	yes: 0, no: 21

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A4H781

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H781

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	22
GO:0016740	transferase activity	2	22

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	53	57	PF00656	0.259
CLV_NRD_NRD_1	108	110	PF00675	0.392
CLV_NRD_NRD_1	22	24	PF00675	0.455
CLV_NRD_NRD_1	262	264	PF00675	0.499
CLV_NRD_NRD_1	6	8	PF00675	0.531
CLV_PCSK_KEX2_1	108	110	PF00082	0.424
CLV_PCSK_KEX2_1	22	24	PF00082	0.455
CLV_PCSK_KEX2_1	262	264	PF00082	0.538
CLV_PCSK_KEX2_1	35	37	PF00082	0.458
CLV_PCSK_KEX2_1	6	8	PF00082	0.549
CLV_PCSK_PC1ET2_1	35	37	PF00082	0.532
CLV_PCSK_PC7_1	104	110	PF00082	0.375
CLV_PCSK_SKI1_1	179	183	PF00082	0.363
CLV_PCSK_SKI1_1	35	39	PF00082	0.480
CLV_PCSK_SKI1_1	41	45	PF00082	0.517
DEG_MDM2_SWIB_1	135	142	PF02201	0.360
DEG_Nend_Nbox_1	1	3	PF02207	0.594
DOC_CYCLIN_RxL_1	187	198	PF00134	0.379
DOC_MAPK_gen_1	41	49	PF00069	0.265
DOC_MAPK_MEF2A_6	193	201	PF00069	0.370
DOC_MAPK_MEF2A_6	41	49	PF00069	0.265
DOC_PP2B_LxvP_1	197	200	PF13499	0.364
DOC_PP4_FxxP_1	42	45	PF00568	0.294
DOC_WW_Pin1_4	159	164	PF00397	0.322
LIG_14-3-3_CanoR_1	6	12	PF00244	0.486
LIG_CtBP_PxDLS_1	89	94	PF00389	0.265
LIG_deltaCOP1_diTrp_1	137	146	PF00928	0.291
LIG_FHA_1	180	186	PF00498	0.349
LIG_FHA_1	200	206	PF00498	0.379
LIG_FHA_1	242	248	PF00498	0.656
LIG_FHA_2	8	14	PF00498	0.497
LIG_LIR_Gen_1	137	144	PF02991	0.284
LIG_LIR_Gen_1	25	34	PF02991	0.305
LIG_LIR_Nem_3	137	142	PF02991	0.270
LIG_LIR_Nem_3	145	149	PF02991	0.366
LIG_LIR_Nem_3	25	30	PF02991	0.314
LIG_LIR_Nem_3	50	55	PF02991	0.220
LIG_LIR_Nem_3	73	79	PF02991	0.273
LIG_Pex14_1	8	12	PF04695	0.516
LIG_Pex14_2	127	131	PF04695	0.232
LIG_Pex14_2	135	139	PF04695	0.360
LIG_SH2_CRK	79	83	PF00017	0.360
LIG_SH2_STAT3	230	233	PF00017	0.358
LIG_SH2_STAT5	16	19	PF00017	0.246
LIG_SH2_STAT5	166	169	PF00017	0.547
LIG_SH2_STAT5	184	187	PF00017	0.353
LIG_SH2_STAT5	223	226	PF00017	0.384
LIG_SH2_STAT5	230	233	PF00017	0.366
LIG_SH3_3	228	234	PF00018	0.359
LIG_WRC_WIRS_1	240	245	PF05994	0.553
MOD_CDK_SPK_2	159	164	PF00069	0.322
MOD_CK1_1	159	165	PF00069	0.491
MOD_CK1_1	242	248	PF00069	0.522
MOD_GlcNHglycan	189	192	PF01048	0.400
MOD_GlcNHglycan	52	55	PF01048	0.463
MOD_GSK3_1	195	202	PF00069	0.365
MOD_GSK3_1	204	211	PF00069	0.343
MOD_NEK2_1	1	6	PF00069	0.496
MOD_NEK2_1	195	200	PF00069	0.421
MOD_NEK2_1	90	95	PF00069	0.346
MOD_NEK2_2	270	275	PF00069	0.564
MOD_PKA_1	249	255	PF00069	0.570
MOD_PKA_2	137	143	PF00069	0.344
MOD_PKA_2	50	56	PF00069	0.249
MOD_Plk_1	179	185	PF00069	0.356
MOD_Plk_1	195	201	PF00069	0.406
MOD_Plk_1	47	53	PF00069	0.360
MOD_Plk_4	226	232	PF00069	0.377
MOD_Plk_4	7	13	PF00069	0.507
MOD_ProDKin_1	159	165	PF00069	0.316
MOD_SUMO_rev_2	221	229	PF00179	0.413
TRG_ER_diArg_1	107	109	PF00400	0.269
TRG_ER_diArg_1	22	24	PF00400	0.258
TRG_ER_diArg_1	262	265	PF00400	0.509
TRG_ER_diArg_1	6	8	PF00400	0.575
TRG_NLS_Bipartite_1	22	39	PF00514	0.332
TRG_Pf-PMV_PEXEL_1	262	266	PF00026	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P896	Leptomonas seymouri	79%	100%
A0A0N1PCD6	Leptomonas seymouri	33%	95%
A0A0S4IK22	Bodo saltans	63%	98%
A0A1X0NN04	Trypanosomatidae	66%	100%
A0A1X0P3F1	Trypanosomatidae	41%	80%
A0A3Q8I9N9	Leishmania donovani	92%	100%
A0A3R7K9Z6	Trypanosoma rangeli	37%	91%
A0A3R7MES7	Trypanosoma rangeli	71%	100%
A0A3S7XB94	Leishmania donovani	32%	96%
A4HPL2	Leishmania braziliensis	31%	96%
A4HVM1	Leishmania infantum	92%	100%
A4ID52	Leishmania infantum	32%	96%
D0A6N3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	70%	77%
D0A8K2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	90%
E9APB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9ATC4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	96%
Q4Q173	Leishmania major	31%	100%
Q4QG61	Leishmania major	91%	100%
V5BK55	Trypanosoma cruzi	69%	100%
V5BS52	Trypanosoma cruzi	35%	91%