C3H1-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H776_LEIBR

TriTrypDb:

LbrM.13.0690 , LBRM2903_130012700

Length:

689

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

A4H776

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H776

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	627	631	PF00656	0.698
CLV_NRD_NRD_1	221	223	PF00675	0.833
CLV_NRD_NRD_1	288	290	PF00675	0.762
CLV_NRD_NRD_1	309	311	PF00675	0.790
CLV_NRD_NRD_1	499	501	PF00675	0.666
CLV_NRD_NRD_1	81	83	PF00675	0.590
CLV_PCSK_KEX2_1	221	223	PF00082	0.833
CLV_PCSK_KEX2_1	288	290	PF00082	0.762
CLV_PCSK_KEX2_1	309	311	PF00082	0.790
CLV_PCSK_KEX2_1	488	490	PF00082	0.665

Previous1 2 3 4 5…20Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDX4	Leptomonas seymouri	54%	100%
A0A3S5H6P0	Leishmania donovani	86%	99%
A4HVL6	Leishmania infantum	86%	99%
E9APB2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	99%
Q4QG66	Leishmania major	86%	100%

Previous1Next