Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H772_LEIBR

TriTrypDb:

LbrM.13.0650 , LBRM2903_130012300

Length:

867

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H772

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H772

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	453	457	PF00656	0.557
CLV_NRD_NRD_1	150	152	PF00675	0.709
CLV_NRD_NRD_1	262	264	PF00675	0.586
CLV_NRD_NRD_1	268	270	PF00675	0.530
CLV_NRD_NRD_1	276	278	PF00675	0.564
CLV_NRD_NRD_1	332	334	PF00675	0.720
CLV_NRD_NRD_1	34	36	PF00675	0.708
CLV_NRD_NRD_1	40	42	PF00675	0.697
CLV_NRD_NRD_1	425	427	PF00675	0.719
CLV_NRD_NRD_1	52	54	PF00675	0.558
CLV_NRD_NRD_1	817	819	PF00675	0.525
CLV_NRD_NRD_1	87	89	PF00675	0.642
CLV_PCSK_FUR_1	260	264	PF00082	0.598
CLV_PCSK_KEX2_1	150	152	PF00082	0.709
CLV_PCSK_KEX2_1	262	264	PF00082	0.599
CLV_PCSK_KEX2_1	275	277	PF00082	0.566
CLV_PCSK_KEX2_1	33	35	PF00082	0.704
CLV_PCSK_KEX2_1	332	334	PF00082	0.720
CLV_PCSK_KEX2_1	40	42	PF00082	0.691
CLV_PCSK_KEX2_1	52	54	PF00082	0.552
CLV_PCSK_KEX2_1	662	664	PF00082	0.650
CLV_PCSK_KEX2_1	86	88	PF00082	0.632
CLV_PCSK_PC1ET2_1	662	664	PF00082	0.587
CLV_PCSK_PC7_1	272	278	PF00082	0.462
CLV_PCSK_PC7_1	82	88	PF00082	0.509
CLV_PCSK_SKI1_1	173	177	PF00082	0.659
CLV_PCSK_SKI1_1	194	198	PF00082	0.644
CLV_PCSK_SKI1_1	341	345	PF00082	0.566
CLV_PCSK_SKI1_1	455	459	PF00082	0.561
CLV_PCSK_SKI1_1	560	564	PF00082	0.453
DEG_SPOP_SBC_1	202	206	PF00917	0.488
DEG_SPOP_SBC_1	708	712	PF00917	0.718
DOC_CDC14_PxL_1	129	137	PF14671	0.614
DOC_CKS1_1	632	637	PF01111	0.531
DOC_MAPK_MEF2A_6	181	190	PF00069	0.569
DOC_PP1_RVXF_1	424	431	PF00149	0.714
DOC_PP1_RVXF_1	542	549	PF00149	0.539
DOC_PP2B_LxvP_1	740	743	PF13499	0.534
DOC_USP7_MATH_1	103	107	PF00917	0.618
DOC_USP7_MATH_1	179	183	PF00917	0.618
DOC_USP7_MATH_1	247	251	PF00917	0.653
DOC_USP7_MATH_1	29	33	PF00917	0.693
DOC_USP7_MATH_1	296	300	PF00917	0.632
DOC_USP7_MATH_1	317	321	PF00917	0.609
DOC_USP7_MATH_1	325	329	PF00917	0.699
DOC_USP7_MATH_1	451	455	PF00917	0.611
DOC_USP7_MATH_1	48	52	PF00917	0.647
DOC_USP7_MATH_1	60	64	PF00917	0.670
DOC_USP7_MATH_1	601	605	PF00917	0.787
DOC_USP7_MATH_1	672	676	PF00917	0.671
DOC_USP7_MATH_1	677	681	PF00917	0.650
DOC_USP7_MATH_1	734	738	PF00917	0.762
DOC_USP7_MATH_1	744	748	PF00917	0.557
DOC_USP7_MATH_1	799	803	PF00917	0.623
DOC_USP7_MATH_1	812	816	PF00917	0.593
DOC_WW_Pin1_4	123	128	PF00397	0.658
DOC_WW_Pin1_4	251	256	PF00397	0.603
DOC_WW_Pin1_4	298	303	PF00397	0.562
DOC_WW_Pin1_4	398	403	PF00397	0.682
DOC_WW_Pin1_4	41	46	PF00397	0.839
DOC_WW_Pin1_4	434	439	PF00397	0.545
DOC_WW_Pin1_4	464	469	PF00397	0.662
DOC_WW_Pin1_4	478	483	PF00397	0.589
DOC_WW_Pin1_4	490	495	PF00397	0.576
DOC_WW_Pin1_4	508	513	PF00397	0.472
DOC_WW_Pin1_4	595	600	PF00397	0.732
DOC_WW_Pin1_4	602	607	PF00397	0.650
DOC_WW_Pin1_4	623	628	PF00397	0.818
DOC_WW_Pin1_4	631	636	PF00397	0.653
DOC_WW_Pin1_4	648	653	PF00397	0.683
DOC_WW_Pin1_4	668	673	PF00397	0.510
DOC_WW_Pin1_4	693	698	PF00397	0.571
DOC_WW_Pin1_4	709	714	PF00397	0.517
DOC_WW_Pin1_4	738	743	PF00397	0.697
DOC_WW_Pin1_4	765	770	PF00397	0.618
DOC_WW_Pin1_4	786	791	PF00397	0.713
DOC_WW_Pin1_4	94	99	PF00397	0.564
LIG_14-3-3_CanoR_1	114	122	PF00244	0.580
LIG_14-3-3_CanoR_1	224	234	PF00244	0.661
LIG_14-3-3_CanoR_1	284	293	PF00244	0.559
LIG_14-3-3_CanoR_1	297	302	PF00244	0.600
LIG_14-3-3_CanoR_1	40	45	PF00244	0.831
LIG_14-3-3_CanoR_1	431	439	PF00244	0.673
LIG_14-3-3_CanoR_1	503	512	PF00244	0.692
LIG_14-3-3_CanoR_1	52	61	PF00244	0.595
LIG_14-3-3_CanoR_1	663	672	PF00244	0.746
LIG_14-3-3_CanoR_1	688	697	PF00244	0.604
LIG_14-3-3_CanoR_1	746	756	PF00244	0.491
LIG_14-3-3_CanoR_1	778	786	PF00244	0.595
LIG_14-3-3_CanoR_1	846	854	PF00244	0.558
LIG_BRCT_BRCA1_1	317	321	PF00533	0.641
LIG_EVH1_1	360	364	PF00568	0.627
LIG_FHA_1	124	130	PF00498	0.646
LIG_FHA_1	202	208	PF00498	0.598
LIG_FHA_1	391	397	PF00498	0.544
LIG_FHA_1	434	440	PF00498	0.780
LIG_FHA_1	66	72	PF00498	0.555
LIG_FHA_1	782	788	PF00498	0.617
LIG_FHA_1	834	840	PF00498	0.653
LIG_FHA_1	849	855	PF00498	0.608
LIG_FHA_2	512	518	PF00498	0.443
LIG_FHA_2	561	567	PF00498	0.477
LIG_FHA_2	757	763	PF00498	0.505
LIG_FHA_2	859	865	PF00498	0.676
LIG_LIR_Apic_2	355	361	PF02991	0.619
LIG_LIR_Gen_1	120	129	PF02991	0.660
LIG_LIR_Gen_1	538	546	PF02991	0.531
LIG_LIR_Nem_3	120	125	PF02991	0.665
LIG_LIR_Nem_3	128	134	PF02991	0.583
LIG_LIR_Nem_3	538	543	PF02991	0.526
LIG_MYND_1	486	490	PF01753	0.564
LIG_MYND_1	786	790	PF01753	0.637
LIG_Pex14_1	748	752	PF04695	0.491
LIG_SH2_NCK_1	107	111	PF00017	0.549
LIG_SH2_NCK_1	408	412	PF00017	0.544
LIG_SH2_SRC	647	650	PF00017	0.564
LIG_SH2_STAP1	681	685	PF00017	0.644
LIG_SH2_STAP1	92	96	PF00017	0.555
LIG_SH2_STAT3	681	684	PF00017	0.552
LIG_SH2_STAT5	134	137	PF00017	0.688
LIG_SH2_STAT5	66	69	PF00017	0.606
LIG_SH2_STAT5	837	840	PF00017	0.690
LIG_SH3_1	483	489	PF00018	0.549
LIG_SH3_3	358	364	PF00018	0.697
LIG_SH3_3	42	48	PF00018	0.812
LIG_SH3_3	483	489	PF00018	0.576
LIG_SH3_3	593	599	PF00018	0.702
LIG_SH3_3	629	635	PF00018	0.571
LIG_SH3_3	646	652	PF00018	0.620
LIG_SH3_3	683	689	PF00018	0.614
LIG_SH3_3	716	722	PF00018	0.714
LIG_SH3_3	727	733	PF00018	0.630
LIG_TRAF2_1	265	268	PF00917	0.489
LIG_TRAF2_1	514	517	PF00917	0.588
LIG_TRAF2_1	790	793	PF00917	0.694
LIG_TRAF2_1	794	797	PF00917	0.657
LIG_WW_1	489	492	PF00397	0.538
LIG_WW_3	170	174	PF00397	0.516
MOD_CDC14_SPxK_1	401	404	PF00782	0.676
MOD_CDC14_SPxK_1	44	47	PF00782	0.692
MOD_CDK_SPK_2	251	256	PF00069	0.564
MOD_CDK_SPK_2	478	483	PF00069	0.552
MOD_CDK_SPxK_1	398	404	PF00069	0.682
MOD_CDK_SPxK_1	41	47	PF00069	0.696
MOD_CDK_SPxxK_3	648	655	PF00069	0.719
MOD_CK1_1	117	123	PF00069	0.685
MOD_CK1_1	228	234	PF00069	0.708
MOD_CK1_1	240	246	PF00069	0.569
MOD_CK1_1	250	256	PF00069	0.596
MOD_CK1_1	320	326	PF00069	0.709
MOD_CK1_1	382	388	PF00069	0.604
MOD_CK1_1	409	415	PF00069	0.724
MOD_CK1_1	43	49	PF00069	0.655
MOD_CK1_1	467	473	PF00069	0.601
MOD_CK1_1	481	487	PF00069	0.636
MOD_CK1_1	493	499	PF00069	0.568
MOD_CK1_1	51	57	PF00069	0.704
MOD_CK1_1	581	587	PF00069	0.618
MOD_CK1_1	604	610	PF00069	0.705
MOD_CK1_1	611	617	PF00069	0.690
MOD_CK1_1	633	639	PF00069	0.603
MOD_CK1_1	65	71	PF00069	0.615
MOD_CK1_1	650	656	PF00069	0.661
MOD_CK1_1	664	670	PF00069	0.666
MOD_CK1_1	680	686	PF00069	0.569
MOD_CK1_1	747	753	PF00069	0.500
MOD_CK1_1	777	783	PF00069	0.646
MOD_CK1_1	791	797	PF00069	0.538
MOD_CK1_1	802	808	PF00069	0.599
MOD_CK1_1	825	831	PF00069	0.567
MOD_CK1_1	833	839	PF00069	0.526
MOD_CK1_1	848	854	PF00069	0.558
MOD_CK1_1	858	864	PF00069	0.537
MOD_CK1_1	94	100	PF00069	0.588
MOD_CK2_1	262	268	PF00069	0.512
MOD_CK2_1	511	517	PF00069	0.457
MOD_CK2_1	756	762	PF00069	0.551
MOD_CK2_1	786	792	PF00069	0.708
MOD_Cter_Amidation	148	151	PF01082	0.589
MOD_DYRK1A_RPxSP_1	41	45	PF00069	0.732
MOD_GlcNHglycan	110	113	PF01048	0.543
MOD_GlcNHglycan	152	157	PF01048	0.620
MOD_GlcNHglycan	181	184	PF01048	0.486
MOD_GlcNHglycan	207	210	PF01048	0.620
MOD_GlcNHglycan	244	248	PF01048	0.704
MOD_GlcNHglycan	334	337	PF01048	0.748
MOD_GlcNHglycan	390	393	PF01048	0.668
MOD_GlcNHglycan	408	411	PF01048	0.707
MOD_GlcNHglycan	495	498	PF01048	0.544
MOD_GlcNHglycan	55	58	PF01048	0.666
MOD_GlcNHglycan	560	563	PF01048	0.555
MOD_GlcNHglycan	584	587	PF01048	0.670
MOD_GlcNHglycan	608	611	PF01048	0.642
MOD_GlcNHglycan	613	616	PF01048	0.601
MOD_GlcNHglycan	62	65	PF01048	0.542
MOD_GlcNHglycan	627	630	PF01048	0.603
MOD_GlcNHglycan	675	678	PF01048	0.708
MOD_GlcNHglycan	690	693	PF01048	0.548
MOD_GlcNHglycan	701	706	PF01048	0.613
MOD_GlcNHglycan	792	796	PF01048	0.674
MOD_GlcNHglycan	800	804	PF01048	0.618
MOD_GlcNHglycan	848	851	PF01048	0.648
MOD_GlcNHglycan	94	97	PF01048	0.732
MOD_GSK3_1	114	121	PF00069	0.521
MOD_GSK3_1	197	204	PF00069	0.599
MOD_GSK3_1	205	212	PF00069	0.613
MOD_GSK3_1	213	220	PF00069	0.587
MOD_GSK3_1	224	231	PF00069	0.705
MOD_GSK3_1	235	242	PF00069	0.654
MOD_GSK3_1	243	250	PF00069	0.616
MOD_GSK3_1	297	304	PF00069	0.590
MOD_GSK3_1	316	323	PF00069	0.674
MOD_GSK3_1	327	334	PF00069	0.681
MOD_GSK3_1	337	344	PF00069	0.615
MOD_GSK3_1	39	46	PF00069	0.632
MOD_GSK3_1	406	413	PF00069	0.701
MOD_GSK3_1	414	421	PF00069	0.669
MOD_GSK3_1	429	436	PF00069	0.612
MOD_GSK3_1	462	469	PF00069	0.672
MOD_GSK3_1	48	55	PF00069	0.687
MOD_GSK3_1	493	500	PF00069	0.600
MOD_GSK3_1	554	561	PF00069	0.583
MOD_GSK3_1	578	585	PF00069	0.719
MOD_GSK3_1	595	602	PF00069	0.570
MOD_GSK3_1	604	611	PF00069	0.630
MOD_GSK3_1	614	621	PF00069	0.556
MOD_GSK3_1	630	637	PF00069	0.587
MOD_GSK3_1	643	650	PF00069	0.634
MOD_GSK3_1	661	668	PF00069	0.662
MOD_GSK3_1	673	680	PF00069	0.661
MOD_GSK3_1	734	741	PF00069	0.615
MOD_GSK3_1	744	751	PF00069	0.483
MOD_GSK3_1	777	784	PF00069	0.676
MOD_GSK3_1	818	825	PF00069	0.612
MOD_GSK3_1	826	833	PF00069	0.588
MOD_GSK3_1	846	853	PF00069	0.728
MOD_LATS_1	38	44	PF00433	0.724
MOD_LATS_1	50	56	PF00433	0.585
MOD_N-GLC_1	103	108	PF02516	0.561
MOD_N-GLC_1	11	16	PF02516	0.679
MOD_N-GLC_1	462	467	PF02516	0.543
MOD_NEK2_1	115	120	PF00069	0.652
MOD_NEK2_1	197	202	PF00069	0.616
MOD_NEK2_1	321	326	PF00069	0.729
MOD_NEK2_1	342	347	PF00069	0.588
MOD_NEK2_1	526	531	PF00069	0.464
MOD_NEK2_1	554	559	PF00069	0.511
MOD_NEK2_1	608	613	PF00069	0.652
MOD_NEK2_1	845	850	PF00069	0.605
MOD_NEK2_2	813	818	PF00069	0.515
MOD_PIKK_1	213	219	PF00454	0.581
MOD_PIKK_1	262	268	PF00454	0.519
MOD_PIKK_1	327	333	PF00454	0.718
MOD_PIKK_1	503	509	PF00454	0.698
MOD_PIKK_1	599	605	PF00454	0.567
MOD_PIKK_1	680	686	PF00454	0.549
MOD_PIKK_1	734	740	PF00454	0.565
MOD_PIKK_1	77	83	PF00454	0.468
MOD_PK_1	237	243	PF00069	0.568
MOD_PKA_1	262	268	PF00069	0.552
MOD_PKA_1	276	282	PF00069	0.561
MOD_PKA_1	332	338	PF00069	0.566
MOD_PKA_1	40	46	PF00069	0.724
MOD_PKA_1	52	58	PF00069	0.568
MOD_PKA_1	662	668	PF00069	0.609
MOD_PKA_1	818	824	PF00069	0.536
MOD_PKA_2	213	219	PF00069	0.644
MOD_PKA_2	225	231	PF00069	0.642
MOD_PKA_2	262	268	PF00069	0.562
MOD_PKA_2	276	282	PF00069	0.583
MOD_PKA_2	296	302	PF00069	0.511
MOD_PKA_2	331	337	PF00069	0.700
MOD_PKA_2	39	45	PF00069	0.811
MOD_PKA_2	430	436	PF00069	0.721
MOD_PKA_2	48	54	PF00069	0.658
MOD_PKA_2	662	668	PF00069	0.738
MOD_PKA_2	77	83	PF00069	0.475
MOD_PKA_2	777	783	PF00069	0.549
MOD_PKA_2	845	851	PF00069	0.549
MOD_PKB_1	222	230	PF00069	0.578
MOD_PKB_1	260	268	PF00069	0.566
MOD_Plk_1	103	109	PF00069	0.603
MOD_Plk_1	247	253	PF00069	0.560
MOD_Plk_1	382	388	PF00069	0.568
MOD_Plk_4	286	292	PF00069	0.539
MOD_Plk_4	578	584	PF00069	0.562
MOD_Plk_4	62	68	PF00069	0.606
MOD_Plk_4	756	762	PF00069	0.496
MOD_Plk_4	833	839	PF00069	0.616
MOD_ProDKin_1	123	129	PF00069	0.657
MOD_ProDKin_1	251	257	PF00069	0.605
MOD_ProDKin_1	298	304	PF00069	0.562
MOD_ProDKin_1	398	404	PF00069	0.683
MOD_ProDKin_1	41	47	PF00069	0.839
MOD_ProDKin_1	434	440	PF00069	0.546
MOD_ProDKin_1	464	470	PF00069	0.663
MOD_ProDKin_1	478	484	PF00069	0.588
MOD_ProDKin_1	490	496	PF00069	0.576
MOD_ProDKin_1	508	514	PF00069	0.459
MOD_ProDKin_1	595	601	PF00069	0.728
MOD_ProDKin_1	602	608	PF00069	0.651
MOD_ProDKin_1	623	629	PF00069	0.817
MOD_ProDKin_1	631	637	PF00069	0.653
MOD_ProDKin_1	648	654	PF00069	0.685
MOD_ProDKin_1	668	674	PF00069	0.510
MOD_ProDKin_1	693	699	PF00069	0.571
MOD_ProDKin_1	709	715	PF00069	0.517
MOD_ProDKin_1	738	744	PF00069	0.695
MOD_ProDKin_1	765	771	PF00069	0.621
MOD_ProDKin_1	786	792	PF00069	0.715
MOD_ProDKin_1	94	100	PF00069	0.562
MOD_SUMO_for_1	461	464	PF00179	0.553
MOD_SUMO_rev_2	265	271	PF00179	0.478
MOD_SUMO_rev_2	449	457	PF00179	0.549
TRG_DiLeu_BaLyEn_6	783	788	PF01217	0.642
TRG_ENDOCYTIC_2	540	543	PF00928	0.527
TRG_ER_diArg_1	260	263	PF00400	0.608
TRG_ER_diArg_1	274	277	PF00400	0.566
TRG_ER_diArg_1	33	35	PF00400	0.728
TRG_ER_diArg_1	86	88	PF00400	0.644
TRG_Pf-PMV_PEXEL_1	191	195	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	534	538	PF00026	0.506
TRG_Pf-PMV_PEXEL_1	544	549	PF00026	0.451

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WSK8	Leishmania donovani	47%	74%
A4HVL2	Leishmania infantum	47%	74%
E9APA8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	76%
Q4QG70	Leishmania major	47%	100%