LeishMANIAdb
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Ubiquitin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ubiquitin-like protein
Gene product:
ubiquitin-like protein
Species:
Leishmania braziliensis
UniProt:
A4H762_LEIBR
TriTrypDb:
LbrM.13.0550 , LBRM2903_130011200
Length:
865

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H762
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H762

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 366 370 PF00656 0.661
CLV_C14_Caspase3-7 744 748 PF00656 0.847
CLV_NRD_NRD_1 376 378 PF00675 0.600
CLV_NRD_NRD_1 479 481 PF00675 0.632
CLV_NRD_NRD_1 541 543 PF00675 0.359
CLV_NRD_NRD_1 650 652 PF00675 0.716
CLV_PCSK_FUR_1 374 378 PF00082 0.597
CLV_PCSK_KEX2_1 376 378 PF00082 0.600
CLV_PCSK_KEX2_1 479 481 PF00082 0.628
CLV_PCSK_KEX2_1 541 543 PF00082 0.359
CLV_PCSK_KEX2_1 650 652 PF00082 0.593
CLV_PCSK_KEX2_1 716 718 PF00082 0.600
CLV_PCSK_KEX2_1 756 758 PF00082 0.613
CLV_PCSK_PC1ET2_1 716 718 PF00082 0.600
CLV_PCSK_PC1ET2_1 756 758 PF00082 0.613
CLV_PCSK_SKI1_1 377 381 PF00082 0.440
CLV_PCSK_SKI1_1 470 474 PF00082 0.364
CLV_PCSK_SKI1_1 756 760 PF00082 0.859
CLV_Separin_Metazoa 543 547 PF03568 0.497
DEG_Nend_UBRbox_1 1 4 PF02207 0.621
DOC_CDC14_PxL_1 617 625 PF14671 0.390
DOC_CKS1_1 765 770 PF01111 0.825
DOC_MAPK_gen_1 374 384 PF00069 0.708
DOC_MAPK_gen_1 650 658 PF00069 0.697
DOC_PIKK_1 14 22 PF02985 0.494
DOC_PP2B_LxvP_1 450 453 PF13499 0.633
DOC_PP2B_LxvP_1 507 510 PF13499 0.370
DOC_PP4_FxxP_1 100 103 PF00568 0.838
DOC_SPAK_OSR1_1 34 38 PF12202 0.636
DOC_USP7_MATH_1 10 14 PF00917 0.629
DOC_USP7_MATH_1 127 131 PF00917 0.567
DOC_USP7_MATH_1 156 160 PF00917 0.702
DOC_USP7_MATH_1 186 190 PF00917 0.826
DOC_USP7_MATH_1 195 199 PF00917 0.626
DOC_USP7_MATH_1 210 214 PF00917 0.732
DOC_USP7_MATH_1 259 263 PF00917 0.710
DOC_USP7_MATH_1 302 306 PF00917 0.583
DOC_USP7_MATH_1 328 332 PF00917 0.673
DOC_USP7_MATH_1 40 44 PF00917 0.608
DOC_USP7_MATH_1 522 526 PF00917 0.654
DOC_USP7_MATH_1 665 669 PF00917 0.636
DOC_USP7_MATH_1 789 793 PF00917 0.720
DOC_USP7_MATH_1 860 864 PF00917 0.554
DOC_WW_Pin1_4 154 159 PF00397 0.826
DOC_WW_Pin1_4 161 166 PF00397 0.726
DOC_WW_Pin1_4 245 250 PF00397 0.859
DOC_WW_Pin1_4 285 290 PF00397 0.678
DOC_WW_Pin1_4 306 311 PF00397 0.671
DOC_WW_Pin1_4 326 331 PF00397 0.813
DOC_WW_Pin1_4 361 366 PF00397 0.712
DOC_WW_Pin1_4 628 633 PF00397 0.611
DOC_WW_Pin1_4 663 668 PF00397 0.760
DOC_WW_Pin1_4 756 761 PF00397 0.860
DOC_WW_Pin1_4 764 769 PF00397 0.729
DOC_WW_Pin1_4 776 781 PF00397 0.510
DOC_WW_Pin1_4 853 858 PF00397 0.561
LIG_14-3-3_CanoR_1 28 32 PF00244 0.608
LIG_14-3-3_CanoR_1 376 384 PF00244 0.707
LIG_14-3-3_CanoR_1 396 400 PF00244 0.544
LIG_14-3-3_CanoR_1 505 510 PF00244 0.554
LIG_14-3-3_CanoR_1 650 658 PF00244 0.697
LIG_Actin_WH2_2 12 30 PF00022 0.491
LIG_BIR_III_2 369 373 PF00653 0.648
LIG_BRCT_BRCA1_1 136 140 PF00533 0.777
LIG_BRCT_BRCA1_1 595 599 PF00533 0.495
LIG_deltaCOP1_diTrp_1 848 853 PF00928 0.821
LIG_FHA_1 210 216 PF00498 0.789
LIG_FHA_1 39 45 PF00498 0.636
LIG_FHA_1 67 73 PF00498 0.636
LIG_FHA_1 753 759 PF00498 0.608
LIG_FHA_1 795 801 PF00498 0.428
LIG_FHA_2 21 27 PF00498 0.636
LIG_FHA_2 282 288 PF00498 0.620
LIG_FHA_2 362 368 PF00498 0.710
LIG_FHA_2 401 407 PF00498 0.823
LIG_FHA_2 527 533 PF00498 0.653
LIG_FHA_2 717 723 PF00498 0.602
LIG_FHA_2 841 847 PF00498 0.572
LIG_HCF-1_HBM_1 549 552 PF13415 0.570
LIG_Integrin_RGD_1 723 725 PF01839 0.631
LIG_LIR_Gen_1 113 123 PF02991 0.761
LIG_LIR_Gen_1 549 559 PF02991 0.553
LIG_LIR_Gen_1 625 634 PF02991 0.355
LIG_LIR_Gen_1 732 743 PF02991 0.841
LIG_LIR_Nem_3 124 128 PF02991 0.635
LIG_LIR_Nem_3 549 555 PF02991 0.554
LIG_LIR_Nem_3 732 738 PF02991 0.837
LIG_LYPXL_yS_3 620 623 PF13949 0.636
LIG_MYND_1 667 671 PF01753 0.687
LIG_NRBOX 468 474 PF00104 0.364
LIG_NRBOX 633 639 PF00104 0.600
LIG_NRP_CendR_1 864 865 PF00754 0.720
LIG_Pex14_1 641 645 PF04695 0.615
LIG_PTAP_UEV_1 157 162 PF05743 0.575
LIG_PTB_Apo_2 222 229 PF02174 0.551
LIG_PTB_Phospho_1 222 228 PF10480 0.546
LIG_SH2_CRK 463 467 PF00017 0.473
LIG_SH2_PTP2 552 555 PF00017 0.561
LIG_SH2_SRC 547 550 PF00017 0.568
LIG_SH2_STAP1 463 467 PF00017 0.337
LIG_SH2_STAP1 645 649 PF00017 0.651
LIG_SH2_STAT5 547 550 PF00017 0.568
LIG_SH2_STAT5 552 555 PF00017 0.478
LIG_SH2_STAT5 580 583 PF00017 0.554
LIG_SH2_STAT5 824 827 PF00017 0.682
LIG_SH3_3 155 161 PF00018 0.582
LIG_SH3_3 232 238 PF00018 0.602
LIG_SH3_3 295 301 PF00018 0.853
LIG_SH3_3 334 340 PF00018 0.654
LIG_SH3_3 659 665 PF00018 0.736
LIG_SH3_3 70 76 PF00018 0.636
LIG_SH3_3 854 860 PF00018 0.554
LIG_SUMO_SIM_anti_2 12 20 PF11976 0.614
LIG_SUMO_SIM_par_1 12 20 PF11976 0.614
LIG_SxIP_EBH_1 374 388 PF03271 0.690
LIG_TRAF2_1 364 367 PF00917 0.715
LIG_TRAF2_1 529 532 PF00917 0.448
LIG_TRAF2_2 289 294 PF00917 0.618
LIG_WRC_WIRS_1 623 628 PF05994 0.375
MOD_CDC14_SPxK_1 329 332 PF00782 0.823
MOD_CDK_SPxK_1 326 332 PF00069 0.814
MOD_CDK_SPxK_1 764 770 PF00069 0.611
MOD_CDK_SPxxK_3 285 292 PF00069 0.605
MOD_CDK_SPxxK_3 756 763 PF00069 0.647
MOD_CK1_1 106 112 PF00069 0.814
MOD_CK1_1 135 141 PF00069 0.762
MOD_CK1_1 152 158 PF00069 0.550
MOD_CK1_1 221 227 PF00069 0.789
MOD_CK1_1 563 569 PF00069 0.588
MOD_CK1_1 58 64 PF00069 0.530
MOD_CK1_1 663 669 PF00069 0.685
MOD_CK1_1 712 718 PF00069 0.586
MOD_CK1_1 84 90 PF00069 0.594
MOD_CK2_1 20 26 PF00069 0.530
MOD_CK2_1 261 267 PF00069 0.649
MOD_CK2_1 281 287 PF00069 0.545
MOD_CK2_1 328 334 PF00069 0.577
MOD_CK2_1 361 367 PF00069 0.709
MOD_CK2_1 400 406 PF00069 0.828
MOD_CK2_1 526 532 PF00069 0.541
MOD_CK2_1 795 801 PF00069 0.681
MOD_CK2_1 809 815 PF00069 0.440
MOD_CK2_1 840 846 PF00069 0.729
MOD_CMANNOS 850 853 PF00535 0.828
MOD_GlcNHglycan 112 115 PF01048 0.790
MOD_GlcNHglycan 118 121 PF01048 0.716
MOD_GlcNHglycan 154 157 PF01048 0.808
MOD_GlcNHglycan 158 161 PF01048 0.725
MOD_GlcNHglycan 188 191 PF01048 0.819
MOD_GlcNHglycan 253 256 PF01048 0.661
MOD_GlcNHglycan 257 260 PF01048 0.672
MOD_GlcNHglycan 298 301 PF01048 0.626
MOD_GlcNHglycan 304 307 PF01048 0.559
MOD_GlcNHglycan 443 446 PF01048 0.398
MOD_GlcNHglycan 524 527 PF01048 0.516
MOD_GlcNHglycan 587 590 PF01048 0.447
MOD_GlcNHglycan 613 616 PF01048 0.347
MOD_GlcNHglycan 626 629 PF01048 0.446
MOD_GlcNHglycan 696 699 PF01048 0.594
MOD_GlcNHglycan 774 777 PF01048 0.813
MOD_GlcNHglycan 797 800 PF01048 0.671
MOD_GlcNHglycan 83 86 PF01048 0.775
MOD_GlcNHglycan 88 93 PF01048 0.833
MOD_GSK3_1 106 113 PF00069 0.773
MOD_GSK3_1 128 135 PF00069 0.741
MOD_GSK3_1 152 159 PF00069 0.814
MOD_GSK3_1 186 193 PF00069 0.607
MOD_GSK3_1 217 224 PF00069 0.777
MOD_GSK3_1 241 248 PF00069 0.829
MOD_GSK3_1 251 258 PF00069 0.687
MOD_GSK3_1 281 288 PF00069 0.640
MOD_GSK3_1 302 309 PF00069 0.610
MOD_GSK3_1 390 397 PF00069 0.822
MOD_GSK3_1 414 421 PF00069 0.758
MOD_GSK3_1 517 524 PF00069 0.620
MOD_GSK3_1 563 570 PF00069 0.367
MOD_GSK3_1 624 631 PF00069 0.422
MOD_GSK3_1 712 719 PF00069 0.630
MOD_GSK3_1 748 755 PF00069 0.629
MOD_GSK3_1 772 779 PF00069 0.774
MOD_GSK3_1 84 91 PF00069 0.595
MOD_GSK3_1 840 847 PF00069 0.829
MOD_N-GLC_1 20 25 PF02516 0.433
MOD_N-GLC_1 323 328 PF02516 0.711
MOD_N-GLC_1 423 428 PF02516 0.857
MOD_N-GLC_1 431 436 PF02516 0.648
MOD_N-GLC_1 461 466 PF02516 0.461
MOD_N-GLC_1 481 486 PF02516 0.703
MOD_N-GLC_1 748 753 PF02516 0.601
MOD_NEK2_1 105 110 PF00069 0.567
MOD_NEK2_1 128 133 PF00069 0.748
MOD_NEK2_1 204 209 PF00069 0.634
MOD_NEK2_1 218 223 PF00069 0.719
MOD_NEK2_1 27 32 PF00069 0.491
MOD_NEK2_1 323 328 PF00069 0.832
MOD_NEK2_1 446 451 PF00069 0.403
MOD_NEK2_1 481 486 PF00069 0.450
MOD_NEK2_1 583 588 PF00069 0.557
MOD_NEK2_1 610 615 PF00069 0.443
MOD_NEK2_1 633 638 PF00069 0.603
MOD_NEK2_1 710 715 PF00069 0.569
MOD_NEK2_2 40 45 PF00069 0.491
MOD_PIKK_1 210 216 PF00454 0.789
MOD_PIKK_1 261 267 PF00454 0.599
MOD_PIKK_1 377 383 PF00454 0.670
MOD_PIKK_1 400 406 PF00454 0.647
MOD_PIKK_1 418 424 PF00454 0.626
MOD_PIKK_1 431 437 PF00454 0.711
MOD_PIKK_1 514 520 PF00454 0.625
MOD_PIKK_1 531 537 PF00454 0.355
MOD_PIKK_1 660 666 PF00454 0.690
MOD_PIKK_1 748 754 PF00454 0.602
MOD_PIKK_1 789 795 PF00454 0.716
MOD_PKA_1 716 722 PF00069 0.599
MOD_PKA_2 27 33 PF00069 0.491
MOD_PKA_2 395 401 PF00069 0.628
MOD_PKA_2 415 421 PF00069 0.764
MOD_PKA_2 649 655 PF00069 0.691
MOD_PKA_2 716 722 PF00069 0.599
MOD_Plk_1 20 26 PF00069 0.433
MOD_Plk_1 293 299 PF00069 0.620
MOD_Plk_1 394 400 PF00069 0.682
MOD_Plk_1 461 467 PF00069 0.460
MOD_Plk_1 484 490 PF00069 0.445
MOD_Plk_1 710 716 PF00069 0.573
MOD_Plk_2-3 20 26 PF00069 0.530
MOD_Plk_4 218 224 PF00069 0.776
MOD_Plk_4 27 33 PF00069 0.491
MOD_Plk_4 352 358 PF00069 0.772
MOD_Plk_4 461 467 PF00069 0.465
MOD_Plk_4 633 639 PF00069 0.554
MOD_Plk_4 665 671 PF00069 0.580
MOD_ProDKin_1 154 160 PF00069 0.825
MOD_ProDKin_1 161 167 PF00069 0.727
MOD_ProDKin_1 245 251 PF00069 0.857
MOD_ProDKin_1 285 291 PF00069 0.679
MOD_ProDKin_1 306 312 PF00069 0.671
MOD_ProDKin_1 326 332 PF00069 0.814
MOD_ProDKin_1 361 367 PF00069 0.709
MOD_ProDKin_1 628 634 PF00069 0.608
MOD_ProDKin_1 663 669 PF00069 0.764
MOD_ProDKin_1 756 762 PF00069 0.859
MOD_ProDKin_1 764 770 PF00069 0.731
MOD_ProDKin_1 776 782 PF00069 0.510
MOD_ProDKin_1 853 859 PF00069 0.560
TRG_DiLeu_BaLyEn_6 42 47 PF01217 0.530
TRG_DiLeu_BaLyEn_6 760 765 PF01217 0.608
TRG_ENDOCYTIC_2 115 118 PF00928 0.811
TRG_ENDOCYTIC_2 463 466 PF00928 0.472
TRG_ENDOCYTIC_2 552 555 PF00928 0.400
TRG_ENDOCYTIC_2 580 583 PF00928 0.554
TRG_ENDOCYTIC_2 620 623 PF00928 0.636
TRG_ER_diArg_1 374 377 PF00400 0.601
TRG_ER_diArg_1 479 481 PF00400 0.478
TRG_ER_diArg_1 48 51 PF00400 0.530
TRG_ER_diArg_1 540 542 PF00400 0.357
TRG_ER_diArg_1 649 651 PF00400 0.693
TRG_ER_diArg_1 816 819 PF00400 0.414
TRG_NES_CRM1_1 26 38 PF08389 0.530
TRG_NES_CRM1_1 441 454 PF08389 0.633
TRG_NES_CRM1_1 543 557 PF08389 0.571
TRG_Pf-PMV_PEXEL_1 376 381 PF00026 0.602
TRG_Pf-PMV_PEXEL_1 470 474 PF00026 0.364
TRG_Pf-PMV_PEXEL_1 500 504 PF00026 0.624
TRG_Pf-PMV_PEXEL_1 528 532 PF00026 0.407
TRG_Pf-PMV_PEXEL_1 740 744 PF00026 0.846

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7WSG5 Leishmania donovani 69% 100%
A4HVK1 Leishmania infantum 69% 100%
E9AP97 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 100%
Q4QG81 Leishmania major 67% 94%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS