Putative RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania braziliensis

UniProt:

A4H739_LEIBR

TriTrypDb:

LbrM.13.0320 , LBRM2903_130008500

Length:

1986

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H739

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0010467	gene expression	4	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1049	1053	PF00656	0.443
CLV_C14_Caspase3-7	152	156	PF00656	0.558
CLV_C14_Caspase3-7	1569	1573	PF00656	0.333
CLV_C14_Caspase3-7	1625	1629	PF00656	0.504
CLV_C14_Caspase3-7	1744	1748	PF00656	0.443
CLV_NRD_NRD_1	1065	1067	PF00675	0.243
CLV_NRD_NRD_1	1388	1390	PF00675	0.336
CLV_NRD_NRD_1	1536	1538	PF00675	0.325
CLV_NRD_NRD_1	1584	1586	PF00675	0.306
CLV_NRD_NRD_1	355	357	PF00675	0.244
CLV_NRD_NRD_1	395	397	PF00675	0.243
CLV_NRD_NRD_1	530	532	PF00675	0.337
CLV_NRD_NRD_1	59	61	PF00675	0.424
CLV_NRD_NRD_1	745	747	PF00675	0.398
CLV_NRD_NRD_1	808	810	PF00675	0.257
CLV_PCSK_KEX2_1	1388	1390	PF00082	0.336
CLV_PCSK_KEX2_1	1584	1586	PF00082	0.306
CLV_PCSK_KEX2_1	1930	1932	PF00082	0.243
CLV_PCSK_KEX2_1	204	206	PF00082	0.446
CLV_PCSK_KEX2_1	220	222	PF00082	0.289
CLV_PCSK_KEX2_1	259	261	PF00082	0.498
CLV_PCSK_KEX2_1	355	357	PF00082	0.243
CLV_PCSK_KEX2_1	375	377	PF00082	0.112
CLV_PCSK_KEX2_1	499	501	PF00082	0.539
CLV_PCSK_KEX2_1	639	641	PF00082	0.368
CLV_PCSK_KEX2_1	808	810	PF00082	0.255
CLV_PCSK_KEX2_1	968	970	PF00082	0.171
CLV_PCSK_PC1ET2_1	1930	1932	PF00082	0.243
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.369
CLV_PCSK_PC1ET2_1	220	222	PF00082	0.400
CLV_PCSK_PC1ET2_1	259	261	PF00082	0.533
CLV_PCSK_PC1ET2_1	375	377	PF00082	0.255
CLV_PCSK_PC1ET2_1	499	501	PF00082	0.568
CLV_PCSK_PC1ET2_1	639	641	PF00082	0.386
CLV_PCSK_PC1ET2_1	968	970	PF00082	0.173
CLV_PCSK_SKI1_1	1018	1022	PF00082	0.268
CLV_PCSK_SKI1_1	1360	1364	PF00082	0.456
CLV_PCSK_SKI1_1	137	141	PF00082	0.310
CLV_PCSK_SKI1_1	1537	1541	PF00082	0.328
CLV_PCSK_SKI1_1	1601	1605	PF00082	0.417
CLV_PCSK_SKI1_1	1612	1616	PF00082	0.323
CLV_PCSK_SKI1_1	166	170	PF00082	0.496
CLV_PCSK_SKI1_1	171	175	PF00082	0.466
CLV_PCSK_SKI1_1	1719	1723	PF00082	0.262
CLV_PCSK_SKI1_1	1798	1802	PF00082	0.329
CLV_PCSK_SKI1_1	332	336	PF00082	0.243
CLV_PCSK_SKI1_1	365	369	PF00082	0.243
CLV_PCSK_SKI1_1	88	92	PF00082	0.378
CLV_PCSK_SKI1_1	910	914	PF00082	0.243
CLV_Separin_Metazoa	1673	1677	PF03568	0.529
DEG_APCC_DBOX_1	443	451	PF00400	0.504
DEG_APCC_DBOX_1	639	647	PF00400	0.356
DEG_SPOP_SBC_1	1467	1471	PF00917	0.443
DOC_CKS1_1	385	390	PF01111	0.443
DOC_CYCLIN_RxL_1	1699	1710	PF00134	0.529
DOC_CYCLIN_RxL_1	1849	1860	PF00134	0.529
DOC_CYCLIN_RxL_1	85	95	PF00134	0.463
DOC_CYCLIN_RxL_1	907	916	PF00134	0.443
DOC_CYCLIN_yCln2_LP_2	1079	1085	PF00134	0.455
DOC_CYCLIN_yCln2_LP_2	1302	1308	PF00134	0.487
DOC_CYCLIN_yCln2_LP_2	1540	1546	PF00134	0.320
DOC_MAPK_DCC_7	1124	1133	PF00069	0.447
DOC_MAPK_gen_1	106	113	PF00069	0.446
DOC_MAPK_gen_1	1213	1221	PF00069	0.500
DOC_MAPK_gen_1	135	143	PF00069	0.315
DOC_MAPK_gen_1	1388	1398	PF00069	0.325
DOC_MAPK_gen_1	238	245	PF00069	0.506
DOC_MAPK_gen_1	516	526	PF00069	0.379
DOC_MAPK_gen_1	531	537	PF00069	0.292
DOC_MAPK_gen_1	60	68	PF00069	0.386
DOC_MAPK_gen_1	639	646	PF00069	0.377
DOC_MAPK_gen_1	907	917	PF00069	0.504
DOC_MAPK_gen_1	968	975	PF00069	0.383
DOC_MAPK_gen_1	992	1000	PF00069	0.368
DOC_MAPK_HePTP_8	1372	1384	PF00069	0.383
DOC_MAPK_MEF2A_6	1003	1011	PF00069	0.516
DOC_MAPK_MEF2A_6	1018	1027	PF00069	0.418
DOC_MAPK_MEF2A_6	1284	1292	PF00069	0.504
DOC_MAPK_MEF2A_6	1341	1349	PF00069	0.362
DOC_MAPK_MEF2A_6	135	143	PF00069	0.315
DOC_MAPK_MEF2A_6	1375	1384	PF00069	0.376
DOC_MAPK_MEF2A_6	1852	1861	PF00069	0.484
DOC_MAPK_MEF2A_6	238	247	PF00069	0.490
DOC_MAPK_MEF2A_6	309	318	PF00069	0.455
DOC_MAPK_MEF2A_6	519	528	PF00069	0.375
DOC_MAPK_MEF2A_6	639	648	PF00069	0.355
DOC_MAPK_RevD_3	383	397	PF00069	0.443
DOC_PP1_RVXF_1	1268	1275	PF00149	0.443
DOC_PP1_RVXF_1	1294	1301	PF00149	0.443
DOC_PP1_RVXF_1	1891	1897	PF00149	0.529
DOC_PP1_RVXF_1	333	339	PF00149	0.455
DOC_PP1_SILK_1	1018	1023	PF00149	0.529
DOC_PP2B_LxvP_1	1079	1082	PF13499	0.455
DOC_PP2B_LxvP_1	1113	1116	PF13499	0.376
DOC_PP2B_LxvP_1	1170	1173	PF13499	0.443
DOC_PP2B_LxvP_1	1302	1305	PF13499	0.487
DOC_PP2B_LxvP_1	1704	1707	PF13499	0.484
DOC_PP2B_LxvP_1	1791	1794	PF13499	0.455
DOC_PP2B_LxvP_1	1832	1835	PF13499	0.529
DOC_PP2B_PxIxI_1	1854	1860	PF00149	0.455
DOC_PP4_FxxP_1	1980	1983	PF00568	0.393
DOC_PP4_FxxP_1	338	341	PF00568	0.443
DOC_PP4_FxxP_1	942	945	PF00568	0.455
DOC_USP7_MATH_1	1116	1120	PF00917	0.458
DOC_USP7_MATH_1	1173	1177	PF00917	0.443
DOC_USP7_MATH_1	1545	1549	PF00917	0.318
DOC_USP7_MATH_1	156	160	PF00917	0.598
DOC_USP7_MATH_1	1667	1671	PF00917	0.487
DOC_USP7_MATH_1	690	694	PF00917	0.326
DOC_USP7_UBL2_3	106	110	PF12436	0.416
DOC_USP7_UBL2_3	1205	1209	PF12436	0.443
DOC_WD40_RPTOR_TOS_1	913	918	PF00400	0.529
DOC_WW_Pin1_4	1070	1075	PF00397	0.529
DOC_WW_Pin1_4	1231	1236	PF00397	0.461
DOC_WW_Pin1_4	1246	1251	PF00397	0.401
DOC_WW_Pin1_4	1373	1378	PF00397	0.371
DOC_WW_Pin1_4	1596	1601	PF00397	0.353
DOC_WW_Pin1_4	1712	1717	PF00397	0.443
DOC_WW_Pin1_4	384	389	PF00397	0.443
DOC_WW_Pin1_4	39	44	PF00397	0.479
LIG_14-3-3_CanoR_1	1093	1100	PF00244	0.443
LIG_14-3-3_CanoR_1	1218	1222	PF00244	0.467
LIG_14-3-3_CanoR_1	1263	1273	PF00244	0.455
LIG_14-3-3_CanoR_1	1360	1365	PF00244	0.478
LIG_14-3-3_CanoR_1	1392	1399	PF00244	0.324
LIG_14-3-3_CanoR_1	1893	1897	PF00244	0.455
LIG_14-3-3_CanoR_1	1934	1943	PF00244	0.487
LIG_14-3-3_CanoR_1	596	603	PF00244	0.340
LIG_14-3-3_CanoR_1	60	65	PF00244	0.428
LIG_14-3-3_CanoR_1	788	797	PF00244	0.443
LIG_14-3-3_CanoR_1	886	890	PF00244	0.548
LIG_14-3-3_CanoR_1	955	964	PF00244	0.516
LIG_14-3-3_CanoR_1	96	103	PF00244	0.535
LIG_Actin_WH2_2	1922	1938	PF00022	0.529
LIG_Actin_WH2_2	738	754	PF00022	0.424
LIG_AP_GAE_1	1631	1637	PF02883	0.285
LIG_AP2alpha_2	1542	1544	PF02296	0.335
LIG_APCC_ABBA_1	1092	1097	PF00400	0.468
LIG_APCC_ABBA_1	1271	1276	PF00400	0.443
LIG_APCC_ABBA_1	800	805	PF00400	0.529
LIG_APCC_ABBAyCdc20_2	1270	1276	PF00400	0.443
LIG_BIR_III_2	1232	1236	PF00653	0.529
LIG_BRCT_BRCA1_1	1040	1044	PF00533	0.478
LIG_BRCT_BRCA1_1	321	325	PF00533	0.529
LIG_CaM_IQ_9	368	384	PF13499	0.443
LIG_Clathr_ClatBox_1	1271	1275	PF01394	0.443
LIG_Clathr_ClatBox_1	1856	1860	PF01394	0.529
LIG_Clathr_ClatBox_1	409	413	PF01394	0.443
LIG_Clathr_ClatBox_1	912	916	PF01394	0.455
LIG_deltaCOP1_diTrp_1	1251	1260	PF00928	0.443
LIG_deltaCOP1_diTrp_1	1328	1336	PF00928	0.350
LIG_deltaCOP1_diTrp_1	1946	1951	PF00928	0.443
LIG_deltaCOP1_diTrp_1	269	275	PF00928	0.363
LIG_DLG_GKlike_1	1588	1595	PF00625	0.480
LIG_DLG_GKlike_1	60	67	PF00625	0.423
LIG_DLG_GKlike_1	969	976	PF00625	0.464
LIG_FHA_1	10	16	PF00498	0.488
LIG_FHA_1	1015	1021	PF00498	0.449
LIG_FHA_1	1071	1077	PF00498	0.529
LIG_FHA_1	1105	1111	PF00498	0.461
LIG_FHA_1	1120	1126	PF00498	0.325
LIG_FHA_1	1232	1238	PF00498	0.468
LIG_FHA_1	1344	1350	PF00498	0.493
LIG_FHA_1	1376	1382	PF00498	0.489
LIG_FHA_1	1421	1427	PF00498	0.428
LIG_FHA_1	1467	1473	PF00498	0.440
LIG_FHA_1	1502	1508	PF00498	0.443
LIG_FHA_1	1518	1524	PF00498	0.397
LIG_FHA_1	1602	1608	PF00498	0.331
LIG_FHA_1	1655	1661	PF00498	0.508
LIG_FHA_1	167	173	PF00498	0.569
LIG_FHA_1	1734	1740	PF00498	0.529
LIG_FHA_1	1882	1888	PF00498	0.461
LIG_FHA_1	1921	1927	PF00498	0.455
LIG_FHA_1	1938	1944	PF00498	0.455
LIG_FHA_1	1957	1963	PF00498	0.488
LIG_FHA_1	224	230	PF00498	0.510
LIG_FHA_1	249	255	PF00498	0.427
LIG_FHA_1	379	385	PF00498	0.443
LIG_FHA_1	532	538	PF00498	0.331
LIG_FHA_1	612	618	PF00498	0.362
LIG_FHA_1	625	631	PF00498	0.362
LIG_FHA_1	735	741	PF00498	0.489
LIG_FHA_1	776	782	PF00498	0.434
LIG_FHA_1	85	91	PF00498	0.335
LIG_FHA_1	875	881	PF00498	0.514
LIG_FHA_1	889	895	PF00498	0.504
LIG_FHA_1	957	963	PF00498	0.443
LIG_FHA_2	1063	1069	PF00498	0.509
LIG_FHA_2	1246	1252	PF00498	0.443
LIG_FHA_2	1450	1456	PF00498	0.455
LIG_FHA_2	147	153	PF00498	0.370
LIG_FHA_2	1567	1573	PF00498	0.355
LIG_FHA_2	1867	1873	PF00498	0.469
LIG_FHA_2	285	291	PF00498	0.548
LIG_FHA_2	372	378	PF00498	0.443
LIG_FHA_2	384	390	PF00498	0.443
LIG_FHA_2	595	601	PF00498	0.354
LIG_FHA_2	811	817	PF00498	0.462
LIG_FHA_2	96	102	PF00498	0.401
LIG_FHA_2	978	984	PF00498	0.476
LIG_FXI_DFP_1	1498	1502	PF00024	0.284
LIG_GBD_Chelix_1	460	468	PF00786	0.385
LIG_Integrin_RGD_1	44	46	PF01839	0.543
LIG_LIR_Apic_2	1979	1983	PF02991	0.547
LIG_LIR_Apic_2	269	273	PF02991	0.462
LIG_LIR_Apic_2	941	945	PF02991	0.468
LIG_LIR_Gen_1	1042	1052	PF02991	0.443
LIG_LIR_Gen_1	1138	1147	PF02991	0.353
LIG_LIR_Gen_1	1155	1162	PF02991	0.390
LIG_LIR_Gen_1	123	134	PF02991	0.341
LIG_LIR_Gen_1	1328	1338	PF02991	0.336
LIG_LIR_Gen_1	1368	1377	PF02991	0.490
LIG_LIR_Gen_1	138	147	PF02991	0.291
LIG_LIR_Gen_1	1408	1419	PF02991	0.368
LIG_LIR_Gen_1	1495	1506	PF02991	0.484
LIG_LIR_Gen_1	1578	1587	PF02991	0.305
LIG_LIR_Gen_1	1682	1689	PF02991	0.444
LIG_LIR_Gen_1	1827	1836	PF02991	0.489
LIG_LIR_Gen_1	1912	1922	PF02991	0.443
LIG_LIR_Gen_1	1975	1983	PF02991	0.548
LIG_LIR_Gen_1	605	611	PF02991	0.348
LIG_LIR_Gen_1	679	689	PF02991	0.449
LIG_LIR_Gen_1	723	731	PF02991	0.318
LIG_LIR_Gen_1	76	86	PF02991	0.334
LIG_LIR_Gen_1	761	771	PF02991	0.368
LIG_LIR_Gen_1	796	803	PF02991	0.511
LIG_LIR_Gen_1	832	838	PF02991	0.445
LIG_LIR_Gen_1	924	931	PF02991	0.446
LIG_LIR_Gen_1	960	971	PF02991	0.529
LIG_LIR_Nem_3	1002	1007	PF02991	0.457
LIG_LIR_Nem_3	1041	1047	PF02991	0.445
LIG_LIR_Nem_3	1145	1150	PF02991	0.266
LIG_LIR_Nem_3	123	129	PF02991	0.342
LIG_LIR_Nem_3	1251	1256	PF02991	0.443
LIG_LIR_Nem_3	1322	1327	PF02991	0.354
LIG_LIR_Nem_3	1328	1334	PF02991	0.321
LIG_LIR_Nem_3	1368	1372	PF02991	0.521
LIG_LIR_Nem_3	138	143	PF02991	0.282
LIG_LIR_Nem_3	145	150	PF02991	0.344
LIG_LIR_Nem_3	1495	1501	PF02991	0.443
LIG_LIR_Nem_3	1578	1582	PF02991	0.311
LIG_LIR_Nem_3	1591	1595	PF02991	0.341
LIG_LIR_Nem_3	1649	1653	PF02991	0.442
LIG_LIR_Nem_3	1682	1687	PF02991	0.444
LIG_LIR_Nem_3	1827	1831	PF02991	0.489
LIG_LIR_Nem_3	1911	1917	PF02991	0.444
LIG_LIR_Nem_3	1948	1954	PF02991	0.455
LIG_LIR_Nem_3	1975	1981	PF02991	0.488
LIG_LIR_Nem_3	331	337	PF02991	0.445
LIG_LIR_Nem_3	389	394	PF02991	0.443
LIG_LIR_Nem_3	478	482	PF02991	0.377
LIG_LIR_Nem_3	485	491	PF02991	0.437
LIG_LIR_Nem_3	605	610	PF02991	0.331
LIG_LIR_Nem_3	679	684	PF02991	0.447
LIG_LIR_Nem_3	719	724	PF02991	0.334
LIG_LIR_Nem_3	725	731	PF02991	0.335
LIG_LIR_Nem_3	76	82	PF02991	0.339
LIG_LIR_Nem_3	761	766	PF02991	0.346
LIG_LIR_Nem_3	791	797	PF02991	0.504
LIG_LIR_Nem_3	832	836	PF02991	0.445
LIG_LIR_Nem_3	924	929	PF02991	0.446
LIG_LIR_Nem_3	960	966	PF02991	0.504
LIG_NRBOX	1042	1048	PF00104	0.464
LIG_NRBOX	63	69	PF00104	0.479
LIG_NRBOX	85	91	PF00104	0.230
LIG_PCNA_PIPBox_1	696	705	PF02747	0.376
LIG_PCNA_yPIPBox_3	1252	1266	PF02747	0.500
LIG_PCNA_yPIPBox_3	873	886	PF02747	0.504
LIG_Pex14_1	1579	1583	PF04695	0.314
LIG_Pex14_2	1158	1162	PF04695	0.468
LIG_Pex14_2	1535	1539	PF04695	0.324
LIG_Pex14_2	1724	1728	PF04695	0.447
LIG_Pex14_2	219	223	PF04695	0.509
LIG_Pex14_2	289	293	PF04695	0.443
LIG_Pex14_2	334	338	PF04695	0.443
LIG_Pex14_2	580	584	PF04695	0.341
LIG_PTB_Apo_2	1586	1593	PF02174	0.341
LIG_PTB_Apo_2	757	764	PF02174	0.456
LIG_PTB_Phospho_1	1586	1592	PF10480	0.351
LIG_REV1ctd_RIR_1	600	608	PF16727	0.442
LIG_SH2_CRK	126	130	PF00017	0.352
LIG_SH2_CRK	1369	1373	PF00017	0.431
LIG_SH2_CRK	1641	1645	PF00017	0.353
LIG_SH2_CRK	1767	1771	PF00017	0.455
LIG_SH2_CRK	1978	1982	PF00017	0.548
LIG_SH2_CRK	206	210	PF00017	0.402
LIG_SH2_CRK	479	483	PF00017	0.374
LIG_SH2_CRK	556	560	PF00017	0.538
LIG_SH2_CRK	756	760	PF00017	0.503
LIG_SH2_CRK	926	930	PF00017	0.529
LIG_SH2_GRB2like	1144	1147	PF00017	0.233
LIG_SH2_GRB2like	79	82	PF00017	0.420
LIG_SH2_GRB2like	883	886	PF00017	0.548
LIG_SH2_NCK_1	797	801	PF00017	0.529
LIG_SH2_PTP2	1200	1203	PF00017	0.443
LIG_SH2_SRC	511	514	PF00017	0.463
LIG_SH2_STAP1	1090	1094	PF00017	0.436
LIG_SH2_STAP1	1095	1099	PF00017	0.433
LIG_SH2_STAP1	1106	1110	PF00017	0.392
LIG_SH2_STAP1	1422	1426	PF00017	0.493
LIG_SH2_STAP1	1885	1889	PF00017	0.468
LIG_SH2_STAP1	1978	1982	PF00017	0.484
LIG_SH2_STAP1	511	515	PF00017	0.410
LIG_SH2_STAP1	724	728	PF00017	0.320
LIG_SH2_STAT3	56	59	PF00017	0.530
LIG_SH2_STAT3	726	729	PF00017	0.318
LIG_SH2_STAT3	848	851	PF00017	0.368
LIG_SH2_STAT3	900	903	PF00017	0.455
LIG_SH2_STAT5	1106	1109	PF00017	0.504
LIG_SH2_STAT5	1200	1203	PF00017	0.443
LIG_SH2_STAT5	1265	1268	PF00017	0.443
LIG_SH2_STAT5	1297	1300	PF00017	0.455
LIG_SH2_STAT5	1357	1360	PF00017	0.438
LIG_SH2_STAT5	1422	1425	PF00017	0.405
LIG_SH2_STAT5	1430	1433	PF00017	0.416
LIG_SH2_STAT5	1490	1493	PF00017	0.452
LIG_SH2_STAT5	1498	1501	PF00017	0.437
LIG_SH2_STAT5	1576	1579	PF00017	0.317
LIG_SH2_STAT5	1581	1584	PF00017	0.309
LIG_SH2_STAT5	1641	1644	PF00017	0.323
LIG_SH2_STAT5	1652	1655	PF00017	0.414
LIG_SH2_STAT5	1738	1741	PF00017	0.455
LIG_SH2_STAT5	1965	1968	PF00017	0.450
LIG_SH2_STAT5	1971	1974	PF00017	0.444
LIG_SH2_STAT5	540	543	PF00017	0.386
LIG_SH2_STAT5	607	610	PF00017	0.397
LIG_SH2_STAT5	724	727	PF00017	0.320
LIG_SH2_STAT5	79	82	PF00017	0.335
LIG_SH2_STAT5	794	797	PF00017	0.443
LIG_SH2_STAT5	848	851	PF00017	0.368
LIG_SH2_STAT5	883	886	PF00017	0.443
LIG_SH2_STAT5	9	12	PF00017	0.276
LIG_SH2_STAT5	900	903	PF00017	0.443
LIG_SH2_STAT5	926	929	PF00017	0.529
LIG_SH3_1	1124	1130	PF00018	0.391
LIG_SH3_2	1127	1132	PF14604	0.392
LIG_SH3_3	1079	1085	PF00018	0.455
LIG_SH3_3	1124	1130	PF00018	0.391
LIG_SH3_3	1312	1318	PF00018	0.490
LIG_SH3_3	1374	1380	PF00018	0.353
LIG_SH3_3	1473	1479	PF00018	0.443
LIG_SH3_3	1496	1502	PF00018	0.455
LIG_SH3_3	1710	1716	PF00018	0.444
LIG_SH3_3	1898	1904	PF00018	0.443
LIG_SH3_3	298	304	PF00018	0.455
LIG_SH3_3	37	43	PF00018	0.489
LIG_SH3_3	382	388	PF00018	0.443
LIG_SH3_3	471	477	PF00018	0.404
LIG_SH3_3	618	624	PF00018	0.320
LIG_SH3_5	1734	1738	PF00018	0.443
LIG_SUMO_SIM_anti_2	115	124	PF11976	0.464
LIG_SUMO_SIM_anti_2	645	650	PF11976	0.330
LIG_SUMO_SIM_anti_2	996	1002	PF11976	0.368
LIG_SUMO_SIM_par_1	1225	1230	PF11976	0.443
LIG_SUMO_SIM_par_1	29	35	PF11976	0.511
LIG_SUMO_SIM_par_1	642	647	PF11976	0.397
LIG_SUMO_SIM_par_1	996	1002	PF11976	0.368
LIG_TRAF2_1	1870	1873	PF00917	0.534
LIG_TRAF2_1	250	253	PF00917	0.565
LIG_TRAF2_1	399	402	PF00917	0.504
LIG_TRAF2_1	510	513	PF00917	0.467
LIG_TRAF2_1	55	58	PF00917	0.355
LIG_TYR_ITIM	1639	1644	PF00017	0.371
LIG_TYR_ITIM	509	514	PF00017	0.381
LIG_TYR_ITIM	754	759	PF00017	0.388
LIG_TYR_ITIM	795	800	PF00017	0.504
LIG_UBA3_1	1790	1798	PF00899	0.529
LIG_UBA3_1	1800	1806	PF00899	0.529
LIG_UBA3_1	975	982	PF00899	0.529
LIG_WRC_WIRS_1	1825	1830	PF05994	0.368
MOD_CDK_SPK_2	1596	1601	PF00069	0.368
MOD_CDK_SPK_2	39	44	PF00069	0.479
MOD_CDK_SPxK_1	1246	1252	PF00069	0.443
MOD_CDK_SPxK_1	384	390	PF00069	0.443
MOD_CDK_SPxxK_3	1712	1719	PF00069	0.443
MOD_CK1_1	1038	1044	PF00069	0.499
MOD_CK1_1	1119	1125	PF00069	0.468
MOD_CK1_1	1176	1182	PF00069	0.443
MOD_CK1_1	1264	1270	PF00069	0.510
MOD_CK1_1	159	165	PF00069	0.524
MOD_CK1_1	1654	1660	PF00069	0.443
MOD_CK1_1	19	25	PF00069	0.476
MOD_CK1_1	1938	1944	PF00069	0.523
MOD_CK1_1	51	57	PF00069	0.611
MOD_CK1_1	780	786	PF00069	0.386
MOD_CK1_1	863	869	PF00069	0.506
MOD_CK1_1	888	894	PF00069	0.462
MOD_CK2_1	1062	1068	PF00069	0.509
MOD_CK2_1	1222	1228	PF00069	0.529
MOD_CK2_1	1245	1251	PF00069	0.443
MOD_CK2_1	1449	1455	PF00069	0.455
MOD_CK2_1	1667	1673	PF00069	0.504
MOD_CK2_1	1866	1872	PF00069	0.502
MOD_CK2_1	263	269	PF00069	0.376
MOD_CK2_1	284	290	PF00069	0.548
MOD_CK2_1	371	377	PF00069	0.443
MOD_CK2_1	383	389	PF00069	0.443
MOD_CK2_1	396	402	PF00069	0.443
MOD_CK2_1	594	600	PF00069	0.358
MOD_CK2_1	711	717	PF00069	0.355
MOD_CK2_1	826	832	PF00069	0.468
MOD_CK2_1	863	869	PF00069	0.455
MOD_CK2_1	95	101	PF00069	0.409
MOD_CK2_1	977	983	PF00069	0.461
MOD_Cter_Amidation	1194	1197	PF01082	0.329
MOD_GlcNHglycan	1036	1040	PF01048	0.315
MOD_GlcNHglycan	1070	1073	PF01048	0.168
MOD_GlcNHglycan	1175	1178	PF01048	0.243
MOD_GlcNHglycan	1228	1232	PF01048	0.243
MOD_GlcNHglycan	1236	1240	PF01048	0.243
MOD_GlcNHglycan	1547	1550	PF01048	0.340
MOD_GlcNHglycan	1563	1566	PF01048	0.385
MOD_GlcNHglycan	161	164	PF01048	0.487
MOD_GlcNHglycan	1743	1746	PF01048	0.264
MOD_GlcNHglycan	1872	1877	PF01048	0.168
MOD_GlcNHglycan	239	242	PF01048	0.561
MOD_GlcNHglycan	36	39	PF01048	0.508
MOD_GlcNHglycan	450	453	PF01048	0.243
MOD_GlcNHglycan	494	497	PF01048	0.567
MOD_GlcNHglycan	50	53	PF01048	0.430
MOD_GlcNHglycan	561	564	PF01048	0.489
MOD_GlcNHglycan	664	668	PF01048	0.402
MOD_GlcNHglycan	828	831	PF01048	0.273
MOD_GlcNHglycan	864	868	PF01048	0.254
MOD_GSK3_1	1031	1038	PF00069	0.468
MOD_GSK3_1	1058	1065	PF00069	0.514
MOD_GSK3_1	1116	1123	PF00069	0.413
MOD_GSK3_1	1227	1234	PF00069	0.463
MOD_GSK3_1	1309	1316	PF00069	0.512
MOD_GSK3_1	1384	1391	PF00069	0.361
MOD_GSK3_1	1601	1608	PF00069	0.318
MOD_GSK3_1	173	180	PF00069	0.564
MOD_GSK3_1	1733	1740	PF00069	0.446
MOD_GSK3_1	1881	1888	PF00069	0.380
MOD_GSK3_1	1935	1942	PF00069	0.531
MOD_GSK3_1	221	228	PF00069	0.388
MOD_GSK3_1	276	283	PF00069	0.360
MOD_GSK3_1	284	291	PF00069	0.437
MOD_GSK3_1	392	399	PF00069	0.468
MOD_GSK3_1	527	534	PF00069	0.345
MOD_GSK3_1	777	784	PF00069	0.557
MOD_GSK3_1	810	817	PF00069	0.364
MOD_GSK3_1	863	870	PF00069	0.444
MOD_GSK3_1	888	895	PF00069	0.520
MOD_GSK3_1	95	102	PF00069	0.382
MOD_GSK3_1	999	1006	PF00069	0.529
MOD_LATS_1	529	535	PF00433	0.332
MOD_N-GLC_1	1661	1666	PF02516	0.232
MOD_N-GLC_1	1844	1849	PF02516	0.329
MOD_N-GLC_1	351	356	PF02516	0.255
MOD_N-GLC_1	492	497	PF02516	0.596
MOD_N-GLC_1	759	764	PF02516	0.448
MOD_N-GLC_1	950	955	PF02516	0.338
MOD_N-GLC_1	956	961	PF02516	0.318
MOD_N-GLC_2	1356	1358	PF02516	0.400
MOD_NEK2_1	121	126	PF00069	0.249
MOD_NEK2_1	1384	1389	PF00069	0.377
MOD_NEK2_1	1466	1471	PF00069	0.443
MOD_NEK2_1	1577	1582	PF00069	0.302
MOD_NEK2_1	1606	1611	PF00069	0.323
MOD_NEK2_1	1935	1940	PF00069	0.529
MOD_NEK2_1	223	228	PF00069	0.438
MOD_NEK2_1	276	281	PF00069	0.395
MOD_NEK2_1	293	298	PF00069	0.376
MOD_NEK2_1	371	376	PF00069	0.443
MOD_NEK2_1	378	383	PF00069	0.443
MOD_NEK2_1	450	455	PF00069	0.443
MOD_NEK2_1	484	489	PF00069	0.421
MOD_NEK2_1	527	532	PF00069	0.355
MOD_NEK2_1	611	616	PF00069	0.305
MOD_NEK2_1	66	71	PF00069	0.354
MOD_NEK2_1	663	668	PF00069	0.517
MOD_NEK2_1	716	721	PF00069	0.343
MOD_NEK2_1	722	727	PF00069	0.303
MOD_NEK2_1	758	763	PF00069	0.453
MOD_NEK2_2	1885	1890	PF00069	0.398
MOD_PIKK_1	1116	1122	PF00454	0.448
MOD_PIKK_1	1152	1158	PF00454	0.447
MOD_PIKK_1	1375	1381	PF00454	0.485
MOD_PIKK_1	156	162	PF00454	0.593
MOD_PIKK_1	177	183	PF00454	0.568
MOD_PIKK_1	248	254	PF00454	0.479
MOD_PIKK_1	293	299	PF00454	0.443
MOD_PIKK_1	378	384	PF00454	0.443
MOD_PIKK_1	402	408	PF00454	0.498
MOD_PIKK_1	630	636	PF00454	0.509
MOD_PIKK_1	690	696	PF00454	0.368
MOD_PIKK_1	73	79	PF00454	0.335
MOD_PIKK_1	831	837	PF00454	0.443
MOD_PIKK_1	869	875	PF00454	0.529
MOD_PK_1	1003	1009	PF00069	0.529
MOD_PK_1	221	227	PF00069	0.403
MOD_PKA_1	1388	1394	PF00069	0.321
MOD_PKA_1	396	402	PF00069	0.468
MOD_PKA_1	531	537	PF00069	0.327
MOD_PKA_1	60	66	PF00069	0.426
MOD_PKA_2	1217	1223	PF00069	0.464
MOD_PKA_2	1388	1394	PF00069	0.321
MOD_PKA_2	1892	1898	PF00069	0.443
MOD_PKA_2	1935	1941	PF00069	0.506
MOD_PKA_2	595	601	PF00069	0.367
MOD_PKA_2	630	636	PF00069	0.388
MOD_PKA_2	860	866	PF00069	0.529
MOD_PKA_2	885	891	PF00069	0.548
MOD_PKA_2	95	101	PF00069	0.404
MOD_PKB_1	1934	1942	PF00069	0.548
MOD_Plk_1	1104	1110	PF00069	0.455
MOD_Plk_1	1116	1122	PF00069	0.392
MOD_Plk_1	1235	1241	PF00069	0.468
MOD_Plk_1	1319	1325	PF00069	0.386
MOD_Plk_1	1449	1455	PF00069	0.458
MOD_Plk_1	1661	1667	PF00069	0.396
MOD_Plk_1	1786	1792	PF00069	0.504
MOD_Plk_1	1844	1850	PF00069	0.529
MOD_Plk_1	1859	1865	PF00069	0.529
MOD_Plk_1	1885	1891	PF00069	0.474
MOD_Plk_1	221	227	PF00069	0.387
MOD_Plk_1	484	490	PF00069	0.426
MOD_Plk_1	676	682	PF00069	0.440
MOD_Plk_1	716	722	PF00069	0.342
MOD_Plk_1	759	765	PF00069	0.449
MOD_Plk_1	810	816	PF00069	0.443
MOD_Plk_1	831	837	PF00069	0.443
MOD_Plk_2-3	146	152	PF00069	0.354
MOD_Plk_2-3	717	723	PF00069	0.442
MOD_Plk_2-3	777	783	PF00069	0.558
MOD_Plk_4	1217	1223	PF00069	0.368
MOD_Plk_4	1320	1326	PF00069	0.365
MOD_Plk_4	1494	1500	PF00069	0.455
MOD_Plk_4	1588	1594	PF00069	0.356
MOD_Plk_4	16	22	PF00069	0.380
MOD_Plk_4	1601	1607	PF00069	0.332
MOD_Plk_4	1639	1645	PF00069	0.297
MOD_Plk_4	1646	1652	PF00069	0.430
MOD_Plk_4	1786	1792	PF00069	0.451
MOD_Plk_4	1897	1903	PF00069	0.441
MOD_Plk_4	1967	1973	PF00069	0.455
MOD_Plk_4	1976	1982	PF00069	0.467
MOD_Plk_4	225	231	PF00069	0.439
MOD_Plk_4	284	290	PF00069	0.446
MOD_Plk_4	484	490	PF00069	0.426
MOD_Plk_4	575	581	PF00069	0.428
MOD_Plk_4	624	630	PF00069	0.353
MOD_Plk_4	711	717	PF00069	0.363
MOD_Plk_4	722	728	PF00069	0.303
MOD_Plk_4	810	816	PF00069	0.455
MOD_Plk_4	875	881	PF00069	0.443
MOD_Plk_4	924	930	PF00069	0.485
MOD_ProDKin_1	1070	1076	PF00069	0.529
MOD_ProDKin_1	1231	1237	PF00069	0.461
MOD_ProDKin_1	1246	1252	PF00069	0.401
MOD_ProDKin_1	1373	1379	PF00069	0.370
MOD_ProDKin_1	1596	1602	PF00069	0.349
MOD_ProDKin_1	1712	1718	PF00069	0.443
MOD_ProDKin_1	384	390	PF00069	0.443
MOD_ProDKin_1	39	45	PF00069	0.483
MOD_SUMO_for_1	1909	1912	PF00179	0.468
MOD_SUMO_rev_2	1210	1217	PF00179	0.521
MOD_SUMO_rev_2	1322	1332	PF00179	0.460
MOD_SUMO_rev_2	1489	1495	PF00179	0.455
MOD_SUMO_rev_2	1737	1745	PF00179	0.457
MOD_SUMO_rev_2	189	199	PF00179	0.501
MOD_SUMO_rev_2	253	261	PF00179	0.565
MOD_SUMO_rev_2	331	337	PF00179	0.481
MOD_SUMO_rev_2	673	678	PF00179	0.328
MOD_SUMO_rev_2	748	754	PF00179	0.406
TRG_DiLeu_BaEn_1	1042	1047	PF01217	0.484
TRG_DiLeu_BaEn_1	1673	1678	PF01217	0.504
TRG_DiLeu_BaEn_2	676	682	PF01217	0.440
TRG_DiLeu_BaEn_4	145	151	PF01217	0.363
TRG_DiLeu_BaEn_4	1682	1688	PF01217	0.468
TRG_DiLeu_BaEn_4	841	847	PF01217	0.451
TRG_DiLeu_BaLyEn_6	139	144	PF01217	0.338
TRG_DiLeu_BaLyEn_6	1852	1857	PF01217	0.455
TRG_DiLeu_BaLyEn_6	405	410	PF01217	0.455
TRG_DiLeu_BaLyEn_6	680	685	PF01217	0.330
TRG_ENDOCYTIC_2	1140	1143	PF00928	0.332
TRG_ENDOCYTIC_2	1147	1150	PF00928	0.326
TRG_ENDOCYTIC_2	126	129	PF00928	0.351
TRG_ENDOCYTIC_2	1369	1372	PF00928	0.437
TRG_ENDOCYTIC_2	1498	1501	PF00928	0.484
TRG_ENDOCYTIC_2	1536	1539	PF00928	0.326
TRG_ENDOCYTIC_2	1541	1544	PF00928	0.321
TRG_ENDOCYTIC_2	1592	1595	PF00928	0.394
TRG_ENDOCYTIC_2	1641	1644	PF00928	0.318
TRG_ENDOCYTIC_2	1650	1653	PF00928	0.422
TRG_ENDOCYTIC_2	1767	1770	PF00928	0.455
TRG_ENDOCYTIC_2	1914	1917	PF00928	0.468
TRG_ENDOCYTIC_2	1971	1974	PF00928	0.455
TRG_ENDOCYTIC_2	1978	1981	PF00928	0.455
TRG_ENDOCYTIC_2	206	209	PF00928	0.387
TRG_ENDOCYTIC_2	457	460	PF00928	0.494
TRG_ENDOCYTIC_2	479	482	PF00928	0.373
TRG_ENDOCYTIC_2	511	514	PF00928	0.378
TRG_ENDOCYTIC_2	556	559	PF00928	0.540
TRG_ENDOCYTIC_2	607	610	PF00928	0.397
TRG_ENDOCYTIC_2	724	727	PF00928	0.320
TRG_ENDOCYTIC_2	756	759	PF00928	0.362
TRG_ENDOCYTIC_2	79	82	PF00928	0.335
TRG_ENDOCYTIC_2	797	800	PF00928	0.504
TRG_ENDOCYTIC_2	926	929	PF00928	0.529
TRG_ER_diArg_1	1294	1297	PF00400	0.443
TRG_ER_diArg_1	134	137	PF00400	0.433
TRG_ER_diArg_1	1583	1585	PF00400	0.307
TRG_ER_diArg_1	355	357	PF00400	0.444
TRG_ER_diArg_1	444	447	PF00400	0.505
TRG_ER_diArg_1	730	733	PF00400	0.312
TRG_ER_diArg_1	807	809	PF00400	0.455
TRG_NES_CRM1_1	1014	1028	PF08389	0.548
TRG_NES_CRM1_1	1694	1710	PF08389	0.504
TRG_NES_CRM1_1	1846	1860	PF08389	0.444
TRG_Pf-PMV_PEXEL_1	112	116	PF00026	0.394
TRG_Pf-PMV_PEXEL_1	142	146	PF00026	0.346
TRG_Pf-PMV_PEXEL_1	1451	1455	PF00026	0.329
TRG_Pf-PMV_PEXEL_1	207	211	PF00026	0.385
TRG_Pf-PMV_PEXEL_1	319	323	PF00026	0.255
TRG_Pf-PMV_PEXEL_1	365	370	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	376	380	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	910	914	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	995	999	PF00026	0.329

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE72	Leptomonas seymouri	30%	84%
A0A0N1PFB3	Leptomonas seymouri	90%	93%
A0A0S4JCP4	Bodo saltans	61%	99%
A0A0S4JQT9	Bodo saltans	29%	93%
A0A1X0NNT2	Trypanosomatidae	68%	89%
A0A3Q8I9S7	Leishmania donovani	30%	84%
A0A3Q8IBN2	Leishmania donovani	95%	92%
A0A3R7KB93	Trypanosoma rangeli	30%	88%
A0A3S5IRN2	Trypanosoma rangeli	68%	94%
A4H938	Leishmania braziliensis	30%	84%
A4HVH9	Leishmania infantum	95%	92%
A4HXH0	Leishmania infantum	27%	100%
C9ZP57	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	89%
D0A6T2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	90%
E1BNG3	Bos taurus	45%	90%
E7F8F4	Danio rerio	46%	100%
E9AP74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9AR65	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	84%
E9PZJ8	Mus musculus	45%	90%
F1LNJ2	Rattus norvegicus	39%	93%
F1LPQ2	Rattus norvegicus	44%	90%
F1NTD6	Gallus gallus	43%	90%
O48534	Arabidopsis thaliana	39%	91%
O60072	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
O75643	Homo sapiens	39%	93%
P32639	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	92%
P53327	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
Q4QE98	Leishmania major	30%	84%
Q4QGA4	Leishmania major	95%	100%
Q54G57	Dictyostelium discoideum	44%	90%
Q55CI8	Dictyostelium discoideum	36%	89%
Q6P4T2	Mus musculus	39%	93%
Q8N3C0	Homo sapiens	45%	90%
Q9FNQ1	Arabidopsis thaliana	44%	92%
Q9SYP1	Arabidopsis thaliana	39%	91%
Q9U2G0	Caenorhabditis elegans	38%	93%
Q9UT24	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	91%
Q9VUV9	Drosophila melanogaster	39%	93%
V5D6H9	Trypanosoma cruzi	30%	89%
V5DBI1	Trypanosoma cruzi	68%	98%