Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H736_LEIBR

TriTrypDb:

LbrM.13.0290

Length:

195

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4H736

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H736

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	157	159	PF00675	0.570
CLV_NRD_NRD_1	33	35	PF00675	0.756
CLV_PCSK_KEX2_1	157	159	PF00082	0.570
CLV_PCSK_KEX2_1	33	35	PF00082	0.756
CLV_PCSK_KEX2_1	79	81	PF00082	0.584
CLV_PCSK_PC1ET2_1	79	81	PF00082	0.584
CLV_PCSK_SKI1_1	34	38	PF00082	0.765
CLV_PCSK_SKI1_1	76	80	PF00082	0.585
DOC_MAPK_gen_1	157	164	PF00069	0.773
DOC_MAPK_gen_1	76	85	PF00069	0.763
DOC_MAPK_MEF2A_6	79	87	PF00069	0.750
DOC_USP7_MATH_1	184	188	PF00917	0.598
DOC_USP7_MATH_1	26	30	PF00917	0.549
DOC_USP7_MATH_1	96	100	PF00917	0.737
LIG_14-3-3_CanoR_1	157	163	PF00244	0.768
LIG_14-3-3_CanoR_1	188	193	PF00244	0.607
LIG_BRCT_BRCA1_1	45	49	PF00533	0.556
LIG_CaM_IQ_9	84	99	PF13499	0.726
LIG_deltaCOP1_diTrp_1	151	155	PF00928	0.733
LIG_eIF4E_1	67	73	PF01652	0.549
LIG_FHA_1	15	21	PF00498	0.549
LIG_FHA_1	173	179	PF00498	0.549
LIG_FHA_1	37	43	PF00498	0.578
LIG_LIR_Gen_1	129	139	PF02991	0.549
LIG_LIR_Gen_1	22	32	PF02991	0.549
LIG_LIR_Gen_1	46	57	PF02991	0.449
LIG_LIR_Nem_3	129	135	PF02991	0.549
LIG_LIR_Nem_3	22	28	PF02991	0.549
LIG_LIR_Nem_3	46	52	PF02991	0.564
LIG_LIR_Nem_3	64	70	PF02991	0.234
LIG_LIR_Nem_3	99	103	PF02991	0.748
LIG_PCNA_PIPBox_1	87	96	PF02747	0.724
LIG_Pex14_2	100	104	PF04695	0.650
LIG_Pex14_2	45	49	PF04695	0.556
LIG_PTB_Apo_2	13	20	PF02174	0.549
LIG_SH2_CRK	123	127	PF00017	0.449
LIG_SH2_CRK	25	29	PF00017	0.549
LIG_SH2_GRB2like	14	17	PF00017	0.549
LIG_SH2_PTP2	27	30	PF00017	0.549
LIG_SH2_PTP2	3	6	PF00017	0.769
LIG_SH2_SRC	25	28	PF00017	0.549
LIG_SH2_STAP1	68	72	PF00017	0.549
LIG_SH2_STAT3	94	97	PF00017	0.729
LIG_SH2_STAT5	14	17	PF00017	0.357
LIG_SH2_STAT5	143	146	PF00017	0.549
LIG_SH2_STAT5	27	30	PF00017	0.322
LIG_SH2_STAT5	3	6	PF00017	0.769
LIG_SH2_STAT5	31	34	PF00017	0.330
LIG_SH2_STAT5	51	54	PF00017	0.199
LIG_SH2_STAT5	71	74	PF00017	0.354
LIG_TYR_ITIM	65	70	PF00017	0.549
LIG_WRC_WIRS_1	42	47	PF05994	0.564
MOD_CK1_1	41	47	PF00069	0.566
MOD_CK2_1	177	183	PF00069	0.549
MOD_CMANNOS	152	155	PF00535	0.534
MOD_GlcNHglycan	170	173	PF01048	0.549
MOD_GlcNHglycan	179	182	PF01048	0.392
MOD_GlcNHglycan	188	191	PF01048	0.575
MOD_GlcNHglycan	8	11	PF01048	0.552
MOD_GSK3_1	168	175	PF00069	0.549
MOD_GSK3_1	184	191	PF00069	0.397
MOD_GSK3_1	37	44	PF00069	0.579
MOD_LATS_1	156	162	PF00433	0.764
MOD_NEK2_1	116	121	PF00069	0.549
MOD_NEK2_1	19	24	PF00069	0.322
MOD_NEK2_1	45	50	PF00069	0.559
MOD_NEK2_1	6	11	PF00069	0.752
MOD_NEK2_2	26	31	PF00069	0.549
MOD_PKA_1	157	163	PF00069	0.768
MOD_PKA_2	157	163	PF00069	0.768
MOD_Plk_1	37	43	PF00069	0.578
MOD_Plk_4	126	132	PF00069	0.549
MOD_Plk_4	19	25	PF00069	0.549
MOD_Plk_4	26	32	PF00069	0.427
MOD_Plk_4	45	51	PF00069	0.325
MOD_Plk_4	55	61	PF00069	0.375
MOD_SUMO_rev_2	179	187	PF00179	0.738
TRG_DiLeu_BaLyEn_6	98	103	PF01217	0.742
TRG_ENDOCYTIC_2	25	28	PF00928	0.549
TRG_ENDOCYTIC_2	3	6	PF00928	0.769
TRG_ENDOCYTIC_2	67	70	PF00928	0.549
TRG_ER_diArg_1	32	34	PF00400	0.546