Tubulin alpha chain

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Tubulin alpha chain

Gene product:

alpha tubulin

Species:

Leishmania braziliensis

UniProt:

A4H727_LEIBR

TriTrypDb:

LbrM.13.0190 , LBRM2903_130007500

Length:

451

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 6
Forrest at al. (procyclic)	no	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 18

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 15

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 15

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005874	microtubule	6	11
GO:0099080	supramolecular complex	2	11
GO:0099081	supramolecular polymer	3	11
GO:0099512	supramolecular fiber	4	11
GO:0099513	polymeric cytoskeletal fiber	5	11
GO:0110165	cellular anatomical entity	1	11
GO:0005737	cytoplasm	2	1

Expansion

Sequence features

A4H727

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H727

Function

Biological processes
Term	Name	Level	Count
GO:0007017	microtubule-based process	2	11
GO:0009987	cellular process	1	11
GO:0000226	microtubule cytoskeleton organization	3	1
GO:0000278	mitotic cell cycle	3	1
GO:0006996	organelle organization	4	1
GO:0007010	cytoskeleton organization	5	1
GO:0007049	cell cycle	2	1
GO:0016043	cellular component organization	3	1
GO:0071840	cellular component organization or biogenesis	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0005198	structural molecule activity	1	11
GO:0005200	structural constituent of cytoskeleton	2	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0017076	purine nucleotide binding	4	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	202	206	PF00656	0.593
CLV_NRD_NRD_1	122	124	PF00675	0.339
CLV_NRD_NRD_1	214	216	PF00675	0.485
CLV_PCSK_KEX2_1	214	216	PF00082	0.485
CLV_PCSK_KEX2_1	338	340	PF00082	0.307
CLV_PCSK_KEX2_1	401	403	PF00082	0.456
CLV_PCSK_PC1ET2_1	338	340	PF00082	0.321
CLV_PCSK_PC1ET2_1	401	403	PF00082	0.456
CLV_PCSK_SKI1_1	401	405	PF00082	0.443
CLV_PCSK_SKI1_1	64	68	PF00082	0.347
CLV_PCSK_SKI1_1	84	88	PF00082	0.187
DEG_APCC_DBOX_1	421	429	PF00400	0.463
DEG_Nend_UBRbox_1	1	4	PF02207	0.473
DOC_CYCLIN_RxL_1	60	71	PF00134	0.446
DOC_CYCLIN_RxL_1	79	90	PF00134	0.545
DOC_MAPK_gen_1	336	343	PF00069	0.515
DOC_MAPK_MEF2A_6	112	119	PF00069	0.539
DOC_MAPK_MEF2A_6	2	9	PF00069	0.400
DOC_MAPK_MEF2A_6	243	252	PF00069	0.470
DOC_PP1_RVXF_1	262	268	PF00149	0.355
DOC_PP1_RVXF_1	337	344	PF00149	0.507
DOC_USP7_MATH_1	175	179	PF00917	0.529
DOC_USP7_MATH_1	274	278	PF00917	0.593
DOC_USP7_MATH_1	32	36	PF00917	0.545
DOC_WW_Pin1_4	171	176	PF00397	0.521
LIG_14-3-3_CanoR_1	156	160	PF00244	0.521
LIG_14-3-3_CanoR_1	214	218	PF00244	0.577
LIG_BRCT_BRCA1_1	240	244	PF00533	0.423
LIG_CAP-Gly_1	445	451	PF01302	0.681
LIG_Clathr_ClatBox_1	23	27	PF01394	0.539
LIG_deltaCOP1_diTrp_1	345	351	PF00928	0.521
LIG_eIF4E_1	312	318	PF01652	0.521
LIG_FHA_1	177	183	PF00498	0.521
LIG_FHA_1	189	195	PF00498	0.521
LIG_FHA_1	237	243	PF00498	0.415
LIG_FHA_1	255	261	PF00498	0.448
LIG_FHA_1	290	296	PF00498	0.593
LIG_FHA_2	200	206	PF00498	0.570
LIG_FHA_2	301	307	PF00498	0.521
LIG_FHA_2	71	77	PF00498	0.534
LIG_GBD_Chelix_1	234	242	PF00786	0.411
LIG_Integrin_RGD_1	320	322	PF01839	0.321
LIG_LIR_Apic_2	170	175	PF02991	0.521
LIG_LIR_Gen_1	183	189	PF02991	0.521
LIG_LIR_Gen_1	223	231	PF02991	0.448
LIG_LIR_Gen_1	386	395	PF02991	0.521
LIG_LIR_Gen_1	429	440	PF02991	0.513
LIG_LIR_Gen_1	46	53	PF02991	0.523
LIG_LIR_Gen_1	65	75	PF02991	0.496
LIG_LIR_Nem_3	183	188	PF02991	0.507
LIG_LIR_Nem_3	223	227	PF02991	0.465
LIG_LIR_Nem_3	270	275	PF02991	0.510
LIG_LIR_Nem_3	386	391	PF02991	0.521
LIG_LIR_Nem_3	429	435	PF02991	0.482
LIG_LIR_Nem_3	46	52	PF02991	0.523
LIG_LIR_Nem_3	65	70	PF02991	0.496
LIG_LIR_Nem_3	80	86	PF02991	0.536
LIG_LYPXL_yS_3	262	265	PF13949	0.375
LIG_NRBOX	148	154	PF00104	0.535
LIG_PCNA_yPIPBox_3	221	235	PF02747	0.442
LIG_Pex14_2	49	53	PF04695	0.521
LIG_PTB_Apo_2	290	297	PF02174	0.521
LIG_Rb_LxCxE_1	22	39	PF01857	0.539
LIG_SH2_CRK	185	189	PF00017	0.521
LIG_SH2_CRK	224	228	PF00017	0.455
LIG_SH2_CRK	272	276	PF00017	0.521
LIG_SH2_CRK	357	361	PF00017	0.521
LIG_SH2_CRK	83	87	PF00017	0.539
LIG_SH2_GRB2like	224	227	PF00017	0.462
LIG_SH2_NCK_1	224	228	PF00017	0.555
LIG_SH2_NCK_1	432	436	PF00017	0.487
LIG_SH2_SRC	272	275	PF00017	0.521
LIG_SH2_SRC	357	360	PF00017	0.521
LIG_SH2_SRC	432	435	PF00017	0.484
LIG_SH2_STAP1	399	403	PF00017	0.445
LIG_SH2_STAT3	282	285	PF00017	0.521
LIG_SH2_STAT5	108	111	PF00017	0.539
LIG_SH2_STAT5	169	172	PF00017	0.521
LIG_SH2_STAT5	224	227	PF00017	0.462
LIG_SH2_STAT5	408	411	PF00017	0.429
LIG_SH3_3	178	184	PF00018	0.521
LIG_SH3_3	257	263	PF00018	0.458
LIG_SH3_3	292	298	PF00018	0.515
LIG_TRAF2_1	443	446	PF00917	0.497
LIG_TYR_ITIM	260	265	PF00017	0.449
LIG_TYR_ITSM	268	275	PF00017	0.521
LIG_WRC_WIRS_1	49	54	PF05994	0.524
MOD_CK1_1	190	196	PF00069	0.540
MOD_CK1_1	236	242	PF00069	0.413
MOD_CK1_1	35	41	PF00069	0.545
MOD_CK2_1	190	196	PF00069	0.509
MOD_CK2_1	291	297	PF00069	0.553
MOD_CK2_1	91	97	PF00069	0.539
MOD_Cter_Amidation	161	164	PF01082	0.321
MOD_GlcNHglycan	146	149	PF01048	0.321
MOD_GlcNHglycan	276	279	PF01048	0.321
MOD_GlcNHglycan	438	441	PF01048	0.598
MOD_GlcNHglycan	93	96	PF01048	0.335
MOD_GSK3_1	167	174	PF00069	0.521
MOD_GSK3_1	195	202	PF00069	0.569
MOD_GSK3_1	234	241	PF00069	0.409
MOD_GSK3_1	250	257	PF00069	0.464
MOD_LATS_1	309	315	PF00433	0.593
MOD_N-GLC_1	127	132	PF02516	0.339
MOD_N-GLC_1	379	384	PF02516	0.321
MOD_N-GLC_2	18	20	PF02516	0.339
MOD_NEK2_1	167	172	PF00069	0.520
MOD_NEK2_1	238	243	PF00069	0.417
MOD_NEK2_1	267	272	PF00069	0.521
MOD_NEK2_1	397	402	PF00069	0.444
MOD_NEK2_1	53	58	PF00069	0.521
MOD_NEK2_2	331	336	PF00069	0.521
MOD_NEK2_2	48	53	PF00069	0.539
MOD_PKA_2	155	161	PF00069	0.521
MOD_PKA_2	213	219	PF00069	0.480
MOD_PKA_2	220	226	PF00069	0.451
MOD_Plk_1	379	385	PF00069	0.521
MOD_Plk_2-3	155	161	PF00069	0.521
MOD_Plk_2-3	199	205	PF00069	0.570
MOD_Plk_2-3	284	290	PF00069	0.521
MOD_Plk_4	167	173	PF00069	0.520
MOD_Plk_4	190	196	PF00069	0.549
MOD_Plk_4	199	205	PF00069	0.583
MOD_Plk_4	291	297	PF00069	0.552
MOD_Plk_4	358	364	PF00069	0.521
MOD_Plk_4	48	54	PF00069	0.539
MOD_Plk_4	70	76	PF00069	0.539
MOD_ProDKin_1	171	177	PF00069	0.521
MOD_SUMO_rev_2	386	395	PF00179	0.521
TRG_DiLeu_BaLyEn_6	226	231	PF01217	0.428
TRG_ENDOCYTIC_2	185	188	PF00928	0.521
TRG_ENDOCYTIC_2	224	227	PF00928	0.462
TRG_ENDOCYTIC_2	262	265	PF00928	0.375
TRG_ENDOCYTIC_2	272	275	PF00928	0.521
TRG_ENDOCYTIC_2	432	435	PF00928	0.484
TRG_ENDOCYTIC_2	83	86	PF00928	0.557
TRG_Pf-PMV_PEXEL_1	123	127	PF00026	0.339
TRG_Pf-PMV_PEXEL_1	215	220	PF00026	0.481
TRG_Pf-PMV_PEXEL_1	229	233	PF00026	0.420
TRG_Pf-PMV_PEXEL_1	64	69	PF00026	0.225

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P449	Leptomonas seymouri	28%	96%
A0A0N0P7H2	Leptomonas seymouri	33%	100%
A0A0N1HR67	Leptomonas seymouri	99%	100%
A0A0S4J7M4	Bodo saltans	33%	100%
A0A0S4KPM6	Bodo saltans	26%	95%
A0A1X0NLP3	Trypanosomatidae	33%	100%
A0A1X0NXK9	Trypanosomatidae	40%	100%
A0A1X0NXS7	Trypanosomatidae	26%	92%
A0A381MCS3	Leishmania infantum	99%	100%
A0A381MS01	Leishmania infantum	40%	100%
A0A3Q8IAD6	Leishmania donovani	27%	96%
A0A3Q8IDE9	Leishmania donovani	33%	100%
A0A3Q8IFB7	Leishmania donovani	40%	100%
A0A3Q8IM37	Leishmania donovani	40%	100%
A0A3R7KU60	Trypanosoma rangeli	27%	95%
A0A3S5H697	Leishmania donovani	40%	100%
A0A3S5H6A0	Leishmania donovani	40%	100%
A0A3S5H6N2	Leishmania donovani	99%	100%
A0A3S5H7U1	Leishmania donovani	40%	100%
A0A422NXM1	Trypanosoma rangeli	33%	100%
A0AAL4	Dictyostelium purpureum	66%	100%
A2AQ07	Mus musculus	39%	100%
A4HBW1	Leishmania braziliensis	29%	96%
A4HC48	Leishmania braziliensis	40%	100%
A4HE31	Leishmania braziliensis	33%	100%
A4HLC8	Leishmania braziliensis	41%	100%
A4HLC9	Leishmania braziliensis	41%	100%
A4HTR0	Leishmania infantum	40%	100%
A4HTR1	Leishmania infantum	40%	100%
A4HZJ3	Leishmania infantum	40%	100%
A4I1D7	Leishmania infantum	33%	100%
A5A6J1	Pan troglodytes	83%	100%
A6NHL2	Homo sapiens	66%	100%
A6NNZ2	Homo sapiens	37%	100%
B9DGT7	Arabidopsis thaliana	88%	100%
B9DHQ0	Arabidopsis thaliana	87%	100%
C9ZIG2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZIG3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	94%	100%
C9ZIG6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	94%	100%
C9ZIG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZJV2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
D0A1A1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	93%
E9AGK7	Leishmania infantum	99%	92%
E9AGW9	Leishmania infantum	27%	96%
E9AMJ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9AMJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AP62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	82%
E9AV85	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	96%
E9AVI3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AXH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B3R4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	91%
O04386	Chlamydomonas incerta	40%	100%
O17449	Manduca sexta	41%	100%
O22347	Eleusine indica	88%	100%
O22348	Eleusine indica	84%	100%
O22349	Eleusine indica	86%	100%
O42786	Dothistroma septosporum	39%	100%
O44388	Trichuris trichiura	40%	100%
O49068	Oryza sativa subsp. japonica	31%	96%
O59837	Phytophthora cinnamomi	41%	100%
O93807	Candida albicans	27%	90%
O94128	Zymoseptoria tritici	72%	100%
P02550	Sus scrofa	83%	100%
P02552	Gallus gallus	83%	100%
P02554	Sus scrofa	40%	100%
P02557	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	99%
P04105	Physarum polycephalum	83%	100%
P04106	Trypanosoma brucei rhodesiense	94%	100%
P04107	Trypanosoma brucei rhodesiense	40%	100%
P04350	Homo sapiens	40%	100%
P04688	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	69%	99%
P04689	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	70%	100%
P04690	Chlamydomonas reinhardtii	40%	100%
P05213	Mus musculus	83%	100%
P05214	Mus musculus	84%	100%
P05219	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	100%
P05220	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	39%	100%
P05304	Giardia intestinalis	40%	100%
P06603	Drosophila melanogaster	83%	100%
P06604	Drosophila melanogaster	81%	100%
P06605	Drosophila melanogaster	83%	100%
P06606	Drosophila melanogaster	62%	98%
P07304	Stylonychia lemnae	86%	100%
P07436	Physarum polycephalum	40%	97%
P07437	Homo sapiens	41%	100%
P08070	Gallus gallus	72%	100%
P08537	Xenopus laevis	82%	100%
P08562	Trypanosoma cruzi	40%	100%
P08841	Drosophila melanogaster	40%	99%
P09203	Gallus gallus	40%	100%
P09204	Chlamydomonas reinhardtii	89%	100%
P09205	Chlamydomonas reinhardtii	89%	100%
P09206	Gallus gallus	40%	100%
P09207	Gallus gallus	39%	100%
P09243	Stylonychia lemnae	88%	100%
P09244	Gallus gallus	41%	100%
P09642	Gallus gallus	79%	100%
P09643	Gallus gallus	77%	100%
P09644	Gallus gallus	80%	100%
P09645	Gallus gallus	80%	100%
P09652	Gallus gallus	40%	100%
P09653	Gallus gallus	40%	100%
P09733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	69%	100%
P09734	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	67%	100%
P0DPH7	Homo sapiens	84%	100%
P0DPH8	Homo sapiens	84%	100%
P10653	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	100%
P10872	Tetrahymena pyriformis	88%	100%
P10873	Toxoplasma gondii	88%	100%
P10874	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	38%	100%
P10875	Candida albicans	38%	100%
P10876	Tetrahymena pyriformis	40%	100%
P10878	Toxoplasma gondii	41%	100%
P11139	Arabidopsis thaliana	84%	100%
P11237	Naegleria gruberi	90%	100%
P11480	Physarum polycephalum	84%	100%
P11481	Volvox carteri	90%	100%
P11482	Volvox carteri	40%	100%
P11833	Paracentrotus lividus	40%	100%
P11857	Stylonychia lemnae	40%	100%
P12411	Arabidopsis thaliana	41%	100%
P12456	Caenorhabditis elegans	41%	100%
P12457	Euglena gracilis	38%	100%
P12458	Physarum polycephalum	39%	99%
P12459	Glycine max	38%	100%
P12460	Glycine max	41%	100%
P12543	Plasmodium yoelii yoelii	85%	100%
P13602	Xenopus laevis	40%	100%
P14140	Plasmodium falciparum	41%	100%
P14640	Zea mays	88%	100%
P14641	Zea mays	88%	100%
P14642	Plasmodium falciparum (isolate K1 / Thailand)	86%	100%
P14643	Plasmodium falciparum (isolate K1 / Thailand)	41%	100%
P16040	Blumeria hordei	38%	100%
P17938	Epichloe typhina	38%	100%
P18025	Zea mays	40%	100%
P18026	Zea mays	40%	100%
P18241	Brugia pahangi	40%	100%
P18258	Paracentrotus lividus	82%	100%
P18288	Oncorhynchus mykiss	83%	100%
P18695	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	99%
P20365	Euplotes crassus	40%	100%
P20802	Achlya klebsiana	40%	100%
P21148	Leishmania mexicana	40%	100%
P22012	Aspergillus flavus	39%	100%
P22013	Colletotrichum graminicola	40%	100%
P22014	Colletotrichum graminicola	39%	100%
P22275	Zea mays	84%	100%
P22852	Polytomella agilis	40%	100%
P23257	Drosophila melanogaster	31%	95%
P23258	Homo sapiens	31%	100%
P23330	Xenopus laevis	31%	100%
P24633	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	72%	100%
P24634	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	66%	100%
P24636	Arabidopsis thaliana	40%	100%
P24637	Pneumocystis carinii	38%	100%
P25295	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P25862	Avena sativa	42%	100%
P28268	Euplotes vannus	87%	100%
P28287	Oxytricha granulifera	89%	100%
P28551	Glycine max	41%	100%
P28752	Oryza sativa subsp. japonica	85%	100%
P29500	Pisum sativum	41%	100%
P29501	Pisum sativum	41%	100%
P29502	Pisum sativum	41%	100%
P29511	Arabidopsis thaliana	88%	100%
P29513	Arabidopsis thaliana	40%	100%
P29514	Arabidopsis thaliana	41%	100%
P29515	Arabidopsis thaliana	41%	100%
P29516	Arabidopsis thaliana	41%	100%
P29517	Arabidopsis thaliana	40%	100%
P30156	Ectocarpus variabilis	40%	100%
P30157	Ectocarpus variabilis	40%	100%
P30436	Oncorhynchus keta	82%	100%
P30668	Schizophyllum commune	40%	100%
P30883	Xenopus laevis	40%	100%
P31017	Entamoeba histolytica	53%	99%
P31863	Hypocrea rufa	39%	100%
P31864	Hypocrea rufa	40%	100%
P32255	Dictyostelium discoideum	66%	99%
P32256	Dictyostelium discoideum	39%	99%
P32348	Microbotryum violaceum	33%	96%
P32882	Gallus gallus	40%	100%
P32924	Geotrichum candidum	39%	100%
P32925	Geotrichum candidum	41%	100%
P32928	Colletotrichum gloeosporioides	39%	100%
P33127	Epichloe coenophiala	38%	100%
P33188	Paramecium tetraurelia	40%	100%
P33623	Anemia phyllitidis	89%	100%
P33624	Anemia phyllitidis	85%	100%
P33625	Euglena gracilis	90%	100%
P33627	Zea mays	86%	100%
P33629	Prunus dulcis	88%	100%
P33630	Anemia phyllitidis	39%	100%
P33631	Anemia phyllitidis	40%	100%
P34108	Naegleria pringsheimi	40%	100%
P34475	Caenorhabditis elegans	30%	100%
P34690	Caenorhabditis elegans	77%	100%
P34785	Anemia phyllitidis	31%	96%
P34786	Euplotoides octocarinatus	31%	98%
P34787	Plasmodium falciparum (isolate NF54)	31%	100%
P35394	Enteroctopus dofleini	41%	100%
P36220	Torpedo marmorata	83%	100%
P36221	Notothenia neglecta	41%	100%
P37392	Lupinus albus	41%	100%
P37832	Oryza sativa subsp. japonica	40%	100%
P38557	Arabidopsis thaliana	30%	95%
P38558	Arabidopsis thaliana	31%	95%
P38668	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	64%	99%
P38669	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	70%	100%
P40633	Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O)	33%	98%
P40904	Colletotrichum gloeosporioides	38%	100%
P40905	Erysiphe pisi	38%	100%
P41351	Tetrahymena thermophila	88%	100%
P41352	Tetrahymena thermophila	40%	100%
P41383	Patella vulgata	83%	100%
P41385	Bombyx mori	38%	100%
P41386	Haliotis discus	41%	100%
P41387	Onchocerca gibsoni	41%	100%
P41388	Venturia inaequalis	38%	100%
P41741	Acremonium chrysogenum	39%	100%
P41742	Ajellomyces capsulatus	37%	100%
P41799	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	39%	100%
P41937	Caenorhabditis elegans	41%	100%
P42271	Drosophila melanogaster	30%	99%
P45960	Oryza sativa subsp. japonica	41%	100%
P46259	Pisum sativum	88%	100%
P46263	Solanum tuberosum	41%	100%
P46264	Solanum tuberosum	41%	100%
P46265	Oryza sativa subsp. japonica	40%	100%
P49741	Schizophyllum commune	69%	100%
P49742	Schizophyllum commune	67%	100%
P50258	Physarum polycephalum	86%	100%
P50259	Porphyra purpurea	40%	99%
P50260	Oomycete-like sp. (strain MacKay2000)	40%	100%
P50261	Oomycete-like sp. (strain MacKay2000)	40%	100%
P50262	Oomycete-like sp. (strain MacKay2000)	41%	100%
P50719	Haemonchus contortus	80%	100%
P52273	Bombyx mori	83%	100%
P52274	Caenorhabditis elegans	68%	100%
P52275	Caenorhabditis elegans	40%	100%
P53371	Ajellomyces capsulatus	68%	100%
P53372	Pneumocystis carinii	74%	100%
P53373	Botryotinia fuckeliana	38%	100%
P53374	Gibberella fujikuroi	38%	100%
P53375	Penicillium digitatum	38%	100%
P53376	Rhynchosporium secalis	39%	100%
P53377	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	98%
P53378	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	95%
P54401	Entamoeba histolytica	31%	100%
P54402	Euplotes aediculatus	31%	98%
P54403	Euplotes crassus	30%	98%
P54404	Euplotes crassus	31%	98%
P54405	Reticulomyxa filosa	32%	94%
P61857	Drosophila melanogaster	39%	100%
P61858	Drosophila hydei	39%	100%
P68360	Meriones unguiculatus	83%	100%
P68361	Cricetulus griseus	83%	100%
P68362	Cricetulus griseus	83%	100%
P68363	Homo sapiens	83%	100%
P68365	Cricetulus griseus	83%	100%
P68366	Homo sapiens	80%	100%
P68367	Macaca fascicularis	80%	100%
P68368	Mus musculus	80%	100%
P68369	Mus musculus	83%	100%
P68370	Rattus norvegicus	83%	100%
P68371	Homo sapiens	40%	100%
P68372	Mus musculus	40%	100%
P68373	Mus musculus	83%	100%
P69893	Cricetulus griseus	41%	100%
P69895	Macaca mulatta	41%	100%
P69897	Rattus norvegicus	41%	100%
P79008	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	40%	100%
P81947	Bos taurus	83%	100%
P81948	Bos taurus	80%	100%
P83130	Drosophila erecta	39%	100%
P83887	Mus musculus	31%	100%
P83888	Rattus norvegicus	31%	100%
P85108	Rattus norvegicus	40%	100%
P87066	Candida albicans	68%	100%
P90548	Euplotoides octocarinatus	31%	98%
P91910	Caenorhabditis elegans	80%	100%
P92120	Encephalitozoon hellem	60%	100%
P93176	Hordeum vulgare	41%	100%
P99024	Mus musculus	41%	100%
Q00264	Aspergillus parasiticus	39%	100%
Q02245	Zea mays	86%	100%
Q04709	Babesia bovis	41%	100%
Q06331	Enteroctopus dofleini	80%	100%
Q08114	Euplotoides octocarinatus	88%	100%
Q08115	Euplotoides octocarinatus	39%	100%
Q0VCD2	Bos taurus	31%	100%
Q0WV25	Arabidopsis thaliana	88%	100%
Q13509	Homo sapiens	40%	100%
Q13885	Homo sapiens	40%	100%
Q17299	Caenorhabditis briggsae	41%	100%
Q24560	Drosophila melanogaster	41%	100%
Q24829	Encephalitozoon hellem	39%	100%
Q25008	Homarus americanus	81%	100%
Q25009	Homarus americanus	40%	100%
Q25563	Naegleria pringsheimi	90%	100%
Q27352	Trypanosoma cruzi	93%	100%
Q27380	Eimeria tenella	41%	100%
Q27U48	Glossina morsitans morsitans	41%	100%
Q28IX8	Xenopus tropicalis	82%	100%
Q2HJ81	Bos taurus	40%	100%
Q2HJ86	Bos taurus	83%	100%
Q2HJB8	Bos taurus	78%	100%
Q2KJD0	Bos taurus	41%	100%
Q2T9S0	Bos taurus	40%	100%
Q2U2U3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	39%	100%
Q2XVP4	Sus scrofa	83%	100%
Q32KM1	Bos taurus	31%	100%
Q32KN8	Bos taurus	83%	100%
Q38771	Avena sativa	85%	100%
Q39445	Cicer arietinum	39%	100%
Q39582	Chlamydomonas reinhardtii	31%	96%
Q39697	Daucus carota	40%	100%
Q3KRE8	Rattus norvegicus	40%	100%
Q3KVN1	Cercospora beticola	39%	100%
Q3MHM5	Bos taurus	40%	100%
Q3UX10	Mus musculus	68%	100%
Q3ZBU7	Bos taurus	40%	100%
Q3ZCJ7	Bos taurus	82%	100%
Q3ZCM7	Homo sapiens	38%	100%
Q40106	Lupinus albus	41%	100%
Q40665	Oryza sativa subsp. japonica	41%	100%
Q40831	Pelvetia fastigiata	84%	100%
Q40832	Pelvetia fastigiata	86%	100%
Q41782	Zea mays	39%	100%
Q41783	Zea mays	41%	100%
Q41784	Zea mays	40%	100%
Q41785	Zea mays	41%	100%
Q41807	Zea mays	31%	96%
Q41808	Zea mays	31%	96%
Q41874	Zea mays	30%	100%
Q42480	Chondrus crispus	41%	100%
Q43473	Hordeum vulgare	86%	100%
Q43594	Oryza sativa subsp. japonica	41%	100%
Q43695	Zea mays	39%	100%
Q43697	Zea mays	41%	100%
Q4HZS8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	38%	100%
Q4P235	Ustilago maydis (strain 521 / FGSC 9021)	40%	100%
Q4Q4C4	Leishmania major	40%	98%
Q4Q9Z8	Leishmania major	33%	99%
Q4QBZ6	Leishmania major	40%	98%
Q4QC95	Leishmania major	27%	100%
Q4QGC5	Leishmania major	99%	100%
Q4QI42	Leishmania major	39%	98%
Q4QRB4	Rattus norvegicus	40%	100%
Q4R4X8	Macaca fascicularis	40%	100%
Q4R538	Macaca fascicularis	83%	100%
Q4R5B3	Macaca fascicularis	40%	100%
Q4R7T7	Macaca fascicularis	23%	100%
Q4R9N3	Cochliobolus heterostrophus	39%	100%
Q4WA70	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	38%	100%
Q52NY7	Metarhizium anisopliae	38%	100%
Q52PV9	Tyrophagus putrescentiae	80%	100%
Q53M52	Oryza sativa subsp. japonica	87%	100%
Q55AR3	Dictyostelium discoideum	33%	98%
Q56WH1	Arabidopsis thaliana	87%	100%
Q56YW9	Arabidopsis thaliana	41%	100%
Q5I2J3	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	70%	100%
Q5R1W4	Pan troglodytes	83%	100%
Q5R943	Pongo abelii	41%	100%
Q5UBX3	Trichophyton rubrum	38%	100%
Q5XIF6	Rattus norvegicus	80%	100%
Q60HC2	Macaca fascicularis	40%	100%
Q68FR8	Rattus norvegicus	84%	100%
Q6AY56	Rattus norvegicus	79%	100%
Q6AYZ1	Rattus norvegicus	83%	100%
Q6B856	Bos taurus	40%	100%
Q6DIM3	Xenopus tropicalis	24%	100%
Q6EVK8	Suillus bovinus	39%	100%
Q6FNU9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	97%
Q6GLE7	Xenopus tropicalis	41%	100%
Q6P9T8	Rattus norvegicus	41%	100%
Q6P9V9	Rattus norvegicus	83%	100%
Q6PEY2	Homo sapiens	82%	100%
Q6QDC9	Zymoseptoria tritici	39%	100%
Q6VAF4	Gossypium hirsutum	41%	100%
Q6VAF5	Gossypium hirsutum	40%	100%
Q6VAF6	Gossypium hirsutum	39%	100%
Q6VAF7	Gossypium hirsutum	40%	100%
Q6VAF8	Gossypium hirsutum	40%	100%
Q6VAF9	Gossypium hirsutum	89%	100%
Q6VAG0	Gossypium hirsutum	88%	100%
Q6VAG1	Gossypium hirsutum	88%	100%
Q71G51	Neospora caninum	88%	100%
Q71U36	Homo sapiens	83%	100%
Q752Y2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	68%	100%
Q75A43	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	96%
Q767L7	Sus scrofa	41%	100%
Q76FS2	Oryza sativa subsp. japonica	40%	100%
Q76FS3	Oryza sativa subsp. japonica	41%	100%
Q7JJU6	Pan troglodytes	41%	100%
Q7KQL5	Plasmodium falciparum (isolate 3D7)	41%	100%
Q7TMM9	Mus musculus	40%	100%
Q7Z9Z2	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	33%	100%
Q84TG9	Neopyropia yezoensis	40%	98%
Q86ZP5	Uncinula necator	38%	100%
Q875L2	Hypocrea virens	39%	100%
Q875L3	Hypocrea virens	39%	100%
Q8H7U1	Oryza sativa subsp. japonica	41%	100%
Q8HZV4	Canis lupus familiaris	24%	100%
Q8J1R4	Suillus bovinus	38%	100%
Q8SRD2	Encephalitozoon cuniculi (strain GB-M1)	30%	100%
Q8SRI6	Encephalitozoon cuniculi (strain GB-M1)	61%	100%
Q8SS99	Encephalitozoon cuniculi (strain GB-M1)	39%	100%
Q8T6A5	Aplysia californica	83%	100%
Q8VCK3	Mus musculus	30%	100%
Q8WP13	Papio hamadryas	38%	100%
Q8WP14	Pan troglodytes	38%	100%
Q8WQ47	Lepidoglyphus destructor	82%	100%
Q8WZE0	Microbotryum violaceum	39%	100%
Q91060	Notophthalmus viridescens	82%	100%
Q91240	Pseudopleuronectes americanus	40%	100%
Q91575	Xenopus laevis	41%	100%
Q92268	Pleurotus sajor-caju	39%	100%
Q922F4	Mus musculus	40%	100%
Q92335	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	70%	100%
Q94570	Homarus americanus	75%	100%
Q94571	Homarus americanus	40%	100%
Q94572	Homarus americanus	81%	100%
Q962P8	Naegleria pringsheimi	59%	100%
Q96460	Hordeum vulgare	87%	100%
Q96TU8	Uromyces fabae	38%	100%
Q9ASR0	Arabidopsis thaliana	41%	100%
Q9BQE3	Homo sapiens	82%	100%
Q9BUF5	Homo sapiens	40%	100%
Q9BVA1	Homo sapiens	40%	100%
Q9C413	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	66%	99%
Q9CWF2	Mus musculus	40%	100%
Q9D6F9	Mus musculus	40%	100%
Q9D6T1	Mus musculus	29%	95%
Q9ERD7	Mus musculus	40%	100%
Q9FT36	Daucus carota	87%	100%
Q9GKK5	Canis lupus familiaris	31%	100%
Q9GSR5	Encephalitozoon intestinalis	38%	100%
Q9H4B7	Homo sapiens	38%	100%
Q9HFQ3	Melampsora lini	39%	100%
Q9JJZ2	Mus musculus	78%	100%
Q9LKI8	Thalassiosira weissflogii	40%	100%
Q9N2N6	Euplotes focardii	40%	100%
Q9NFZ5	Echinococcus multilocularis	40%	100%
Q9NFZ6	Echinococcus multilocularis	41%	100%
Q9NFZ7	Echinococcus multilocularis	41%	100%
Q9NRH3	Homo sapiens	30%	100%
Q9NY65	Homo sapiens	78%	100%
Q9R1K7	Mus musculus	24%	99%
Q9SCC8	Guillardia theta	78%	100%
Q9SEA4	Guillardia theta	22%	100%
Q9SEV2	Guillardia theta	39%	100%
Q9UJT0	Homo sapiens	29%	95%
Q9UJT1	Homo sapiens	23%	100%
Q9UV72	Pestalotiopsis microspora	38%	100%
Q9VRX3	Drosophila melanogaster	34%	98%
Q9XFG3	Physcomitrium patens	31%	95%
Q9Y882	Schizosaccharomyces japonicus	33%	100%
Q9YHC3	Gadus morhua	41%	100%
Q9ZPN7	Eleusine indica	41%	100%
Q9ZPN8	Eleusine indica	40%	100%
Q9ZPN9	Eleusine indica	41%	100%
Q9ZPP0	Eleusine indica	40%	100%
Q9ZRA8	Triticum aestivum	41%	100%
Q9ZRA9	Triticum aestivum	40%	100%
Q9ZRB0	Triticum aestivum	40%	100%
Q9ZRB1	Triticum aestivum	41%	100%
Q9ZRB2	Triticum aestivum	41%	100%
Q9ZRB7	Triticum aestivum	87%	100%
Q9ZRJ4	Chlorella vulgaris	90%	100%
Q9ZRR5	Hordeum vulgare	88%	100%
Q9ZSW1	Cyanophora paradoxa	39%	100%
R9TL42	Trypanosoma rangeli	40%	100%
R9TNG7	Trypanosoma rangeli	94%	100%
V5AR05	Trypanosoma cruzi	28%	95%
V5DCF0	Trypanosoma cruzi	33%	100%