TACC_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H719_LEIBR

TriTrypDb:

LbrM.13.0110 , LBRM2903_130006300

Length:

160

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0051286	cell tip	3	1
GO:0060187	cell pole	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H719

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H719

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	95	99	PF00656	0.532
CLV_NRD_NRD_1	113	115	PF00675	0.486
CLV_NRD_NRD_1	73	75	PF00675	0.528
CLV_PCSK_KEX2_1	135	137	PF00082	0.403
CLV_PCSK_KEX2_1	73	75	PF00082	0.606
CLV_PCSK_PC1ET2_1	135	137	PF00082	0.403
DEG_SPOP_SBC_1	4	8	PF00917	0.533
DOC_MAPK_gen_1	135	141	PF00069	0.503
DOC_USP7_MATH_1	18	22	PF00917	0.613
DOC_USP7_UBL2_3	96	100	PF12436	0.372
DOC_WW_Pin1_4	139	144	PF00397	0.511
DOC_WW_Pin1_4	31	36	PF00397	0.585
LIG_14-3-3_CanoR_1	30	35	PF00244	0.489
LIG_APCC_ABBA_1	104	109	PF00400	0.417
LIG_BIR_II_1	1	5	PF00653	0.543
LIG_BRCT_BRCA1_1	128	132	PF00533	0.464
LIG_FHA_1	26	32	PF00498	0.508
LIG_FHA_2	36	42	PF00498	0.441
LIG_MLH1_MIPbox_1	128	132	PF16413	0.464
LIG_REV1ctd_RIR_1	129	140	PF16727	0.468
LIG_SH2_STAP1	120	124	PF00017	0.412
LIG_SH2_STAP1	83	87	PF00017	0.382
LIG_SH2_STAT5	130	133	PF00017	0.466
LIG_SUMO_SIM_par_1	102	109	PF11976	0.484
LIG_TRAF2_1	123	126	PF00917	0.398
LIG_WRC_WIRS_1	145	150	PF05994	0.472
MOD_CDK_SPxxK_3	139	146	PF00069	0.528
MOD_CK1_1	33	39	PF00069	0.513
MOD_CK2_1	61	67	PF00069	0.387
MOD_GlcNHglycan	1	4	PF01048	0.573
MOD_GlcNHglycan	148	151	PF01048	0.600
MOD_GSK3_1	12	19	PF00069	0.584
MOD_GSK3_1	25	32	PF00069	0.576
MOD_LATS_1	144	150	PF00433	0.430
MOD_NEK2_1	124	129	PF00069	0.372
MOD_PIKK_1	5	11	PF00454	0.598
MOD_PIKK_1	68	74	PF00454	0.620
MOD_PKA_1	73	79	PF00069	0.585
MOD_PKA_2	29	35	PF00069	0.493
MOD_PKA_2	73	79	PF00069	0.597
MOD_ProDKin_1	139	145	PF00069	0.518
MOD_ProDKin_1	31	37	PF00069	0.578
MOD_SUMO_rev_2	127	137	PF00179	0.464
MOD_SUMO_rev_2	80	89	PF00179	0.387
MOD_SUMO_rev_2	92	101	PF00179	0.317
TRG_ENDOCYTIC_2	138	141	PF00928	0.441
TRG_ER_diArg_1	48	51	PF00400	0.546
TRG_NES_CRM1_1	41	53	PF08389	0.369
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.370

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKU6	Leptomonas seymouri	63%	100%
A0A1X0NNB7	Trypanosomatidae	43%	100%
A0A3S7WSC0	Leishmania donovani	80%	100%
A4HVE8	Leishmania infantum	80%	100%
E9AP46	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4QGE2	Leishmania major	79%	100%