CCDC92 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H711_LEIBR

TriTrypDb:

LbrM.13.0030 , LBRM2903_130005400

Length:

199

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H711

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H711

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	197	199	PF00675	0.773
CLV_NRD_NRD_1	34	36	PF00675	0.499
CLV_NRD_NRD_1	45	47	PF00675	0.511
CLV_PCSK_KEX2_1	34	36	PF00082	0.501
CLV_PCSK_KEX2_1	45	47	PF00082	0.517
CLV_PCSK_SKI1_1	120	124	PF00082	0.634
CLV_PCSK_SKI1_1	187	191	PF00082	0.677
DEG_APCC_DBOX_1	119	127	PF00400	0.629
DEG_Nend_UBRbox_2	1	3	PF02207	0.618
DOC_CKS1_1	130	135	PF01111	0.664
DOC_CYCLIN_yCln2_LP_2	130	136	PF00134	0.550
DOC_USP7_MATH_1	103	107	PF00917	0.601
DOC_USP7_MATH_1	118	122	PF00917	0.574
DOC_WW_Pin1_4	129	134	PF00397	0.578
DOC_WW_Pin1_4	143	148	PF00397	0.462
LIG_14-3-3_CanoR_1	109	115	PF00244	0.536
LIG_14-3-3_CanoR_1	165	173	PF00244	0.625
LIG_14-3-3_CanoR_1	45	49	PF00244	0.577
LIG_APCC_ABBA_1	99	104	PF00400	0.464
LIG_FHA_1	130	136	PF00498	0.635
LIG_FHA_1	94	100	PF00498	0.579
LIG_FHA_2	56	62	PF00498	0.513
LIG_LIR_Gen_1	79	85	PF02991	0.509
LIG_PTB_Apo_2	125	132	PF02174	0.649
LIG_PTB_Phospho_1	125	131	PF10480	0.649
LIG_SH2_CRK	131	135	PF00017	0.524
LIG_SH2_CRK	142	146	PF00017	0.561
LIG_SH2_NCK_1	26	30	PF00017	0.657
LIG_SH2_STAT3	73	76	PF00017	0.523
LIG_SH2_STAT5	131	134	PF00017	0.519
LIG_SH2_STAT5	142	145	PF00017	0.488
LIG_SUMO_SIM_anti_2	121	127	PF11976	0.633
LIG_SUMO_SIM_anti_2	154	161	PF11976	0.674
LIG_SUMO_SIM_par_1	10	15	PF11976	0.641
MOD_CK1_1	93	99	PF00069	0.603
MOD_CK2_1	55	61	PF00069	0.493
MOD_CK2_1	64	70	PF00069	0.617
MOD_GlcNHglycan	116	119	PF01048	0.591
MOD_GlcNHglycan	13	17	PF01048	0.494
MOD_GlcNHglycan	193	196	PF01048	0.636
MOD_GSK3_1	110	117	PF00069	0.605
MOD_GSK3_1	143	150	PF00069	0.643
MOD_GSK3_1	153	160	PF00069	0.504
MOD_N-GLC_1	165	170	PF02516	0.707
MOD_NEK2_1	64	69	PF00069	0.521
MOD_PIKK_1	64	70	PF00454	0.629
MOD_PIKK_1	84	90	PF00454	0.684
MOD_PKA_2	164	170	PF00069	0.604
MOD_PKA_2	44	50	PF00069	0.577
MOD_PKA_2	55	61	PF00069	0.458
MOD_Plk_4	140	146	PF00069	0.614
MOD_Plk_4	153	159	PF00069	0.511
MOD_ProDKin_1	129	135	PF00069	0.578
MOD_ProDKin_1	143	149	PF00069	0.462
TRG_ENDOCYTIC_2	131	134	PF00928	0.506
TRG_ENDOCYTIC_2	142	145	PF00928	0.543
TRG_ENDOCYTIC_2	26	29	PF00928	0.662
TRG_ER_diArg_1	170	173	PF00400	0.649
TRG_ER_diArg_1	19	22	PF00400	0.576
TRG_ER_diArg_1	34	37	PF00400	0.482
TRG_ER_diArg_1	53	56	PF00400	0.490

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBD1	Leptomonas seymouri	66%	100%
A0A1X0NGP9	Trypanosomatidae	48%	95%
A0A3R7KHE2	Trypanosoma rangeli	45%	96%
A0A3S7WS88	Leishmania donovani	83%	99%
A4HVD9	Leishmania infantum	83%	99%
C9ZTQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	96%
E9AP37	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	99%
Q4QGF1	Leishmania major	83%	100%