Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H6W4_LEIBR

TriTrypDb:

LbrM.12.0510 , LBRM2903_120011400

Length:

829

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6W4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6W4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	236	240	PF00656	0.793
CLV_C14_Caspase3-7	310	314	PF00656	0.682
CLV_C14_Caspase3-7	413	417	PF00656	0.745
CLV_C14_Caspase3-7	429	433	PF00656	0.422
CLV_C14_Caspase3-7	603	607	PF00656	0.825
CLV_C14_Caspase3-7	673	677	PF00656	0.821
CLV_NRD_NRD_1	153	155	PF00675	0.710
CLV_NRD_NRD_1	180	182	PF00675	0.698
CLV_NRD_NRD_1	231	233	PF00675	0.739
CLV_NRD_NRD_1	349	351	PF00675	0.482
CLV_NRD_NRD_1	43	45	PF00675	0.812
CLV_NRD_NRD_1	571	573	PF00675	0.767
CLV_NRD_NRD_1	74	76	PF00675	0.820
CLV_NRD_NRD_1	793	795	PF00675	0.521
CLV_PCSK_KEX2_1	153	155	PF00082	0.710
CLV_PCSK_KEX2_1	174	176	PF00082	0.711
CLV_PCSK_KEX2_1	180	182	PF00082	0.669
CLV_PCSK_KEX2_1	233	235	PF00082	0.752
CLV_PCSK_KEX2_1	349	351	PF00082	0.482
CLV_PCSK_KEX2_1	42	44	PF00082	0.697
CLV_PCSK_KEX2_1	74	76	PF00082	0.820
CLV_PCSK_KEX2_1	821	823	PF00082	0.518
CLV_PCSK_PC1ET2_1	174	176	PF00082	0.802
CLV_PCSK_PC1ET2_1	233	235	PF00082	0.810
CLV_PCSK_PC1ET2_1	42	44	PF00082	0.697
CLV_PCSK_PC1ET2_1	821	823	PF00082	0.518
CLV_PCSK_PC7_1	149	155	PF00082	0.799
CLV_PCSK_PC7_1	817	823	PF00082	0.502
CLV_PCSK_SKI1_1	181	185	PF00082	0.693
CLV_PCSK_SKI1_1	318	322	PF00082	0.644
CLV_PCSK_SKI1_1	468	472	PF00082	0.648
CLV_PCSK_SKI1_1	797	801	PF00082	0.507
CLV_Separin_Metazoa	798	802	PF03568	0.617
DEG_ODPH_VHL_1	108	119	PF01847	0.820
DEG_SPOP_SBC_1	225	229	PF00917	0.802
DEG_SPOP_SBC_1	495	499	PF00917	0.694
DEG_SPOP_SBC_1	501	505	PF00917	0.658
DEG_SPOP_SBC_1	702	706	PF00917	0.775
DOC_CDC14_PxL_1	745	753	PF14671	0.760
DOC_CYCLIN_RxL_1	795	807	PF00134	0.609
DOC_MAPK_FxFP_2	752	755	PF00069	0.743
DOC_MAPK_gen_1	476	484	PF00069	0.648
DOC_PP4_FxxP_1	549	552	PF00568	0.721
DOC_PP4_FxxP_1	752	755	PF00568	0.634
DOC_USP7_MATH_1	10	14	PF00917	0.733
DOC_USP7_MATH_1	100	104	PF00917	0.811
DOC_USP7_MATH_1	122	126	PF00917	0.793
DOC_USP7_MATH_1	243	247	PF00917	0.795
DOC_USP7_MATH_1	255	259	PF00917	0.588
DOC_USP7_MATH_1	271	275	PF00917	0.531
DOC_USP7_MATH_1	470	474	PF00917	0.642
DOC_USP7_MATH_1	501	505	PF00917	0.711
DOC_USP7_MATH_1	529	533	PF00917	0.777
DOC_USP7_MATH_1	534	538	PF00917	0.724
DOC_USP7_MATH_1	600	604	PF00917	0.735
DOC_USP7_MATH_1	629	633	PF00917	0.756
DOC_USP7_MATH_1	640	644	PF00917	0.742
DOC_USP7_MATH_1	66	70	PF00917	0.800
DOC_USP7_MATH_1	680	684	PF00917	0.810
DOC_USP7_MATH_1	702	706	PF00917	0.775
DOC_USP7_MATH_1	707	711	PF00917	0.681
DOC_USP7_MATH_1	80	84	PF00917	0.567
DOC_USP7_UBL2_3	474	478	PF12436	0.530
DOC_WW_Pin1_4	108	113	PF00397	0.829
DOC_WW_Pin1_4	144	149	PF00397	0.681
DOC_WW_Pin1_4	15	20	PF00397	0.710
DOC_WW_Pin1_4	197	202	PF00397	0.745
DOC_WW_Pin1_4	215	220	PF00397	0.814
DOC_WW_Pin1_4	253	258	PF00397	0.795
DOC_WW_Pin1_4	520	525	PF00397	0.784
DOC_WW_Pin1_4	544	549	PF00397	0.749
DOC_WW_Pin1_4	552	557	PF00397	0.655
DOC_WW_Pin1_4	607	612	PF00397	0.817
DOC_WW_Pin1_4	62	67	PF00397	0.761
DOC_WW_Pin1_4	753	758	PF00397	0.724
DOC_WW_Pin1_4	76	81	PF00397	0.596
DOC_WW_Pin1_4	85	90	PF00397	0.700
LIG_14-3-3_CanoR_1	101	107	PF00244	0.700
LIG_14-3-3_CanoR_1	138	148	PF00244	0.746
LIG_14-3-3_CanoR_1	153	158	PF00244	0.560
LIG_14-3-3_CanoR_1	350	356	PF00244	0.597
LIG_14-3-3_CanoR_1	526	536	PF00244	0.814
LIG_14-3-3_CanoR_1	572	582	PF00244	0.792
LIG_14-3-3_CanoR_1	668	678	PF00244	0.766
LIG_APCC_ABBAyCdc20_2	329	335	PF00400	0.661
LIG_BIR_III_2	251	255	PF00653	0.799
LIG_BRCT_BRCA1_1	124	128	PF00533	0.786
LIG_BRCT_BRCA1_1	227	231	PF00533	0.812
LIG_BRCT_BRCA1_1	502	506	PF00533	0.769
LIG_BRCT_BRCA1_1	545	549	PF00533	0.834
LIG_BRCT_BRCA1_2	124	130	PF00533	0.784
LIG_BRCT_BRCA1_2	227	233	PF00533	0.813
LIG_CSL_BTD_1	648	651	PF09270	0.792
LIG_EVH1_1	754	758	PF00568	0.622
LIG_FHA_1	184	190	PF00498	0.728
LIG_FHA_1	278	284	PF00498	0.806
LIG_FHA_1	400	406	PF00498	0.717
LIG_FHA_1	508	514	PF00498	0.798
LIG_FHA_1	56	62	PF00498	0.815
LIG_FHA_1	608	614	PF00498	0.823
LIG_FHA_1	621	627	PF00498	0.679
LIG_FHA_1	636	642	PF00498	0.546
LIG_FHA_1	68	74	PF00498	0.587
LIG_FHA_1	91	97	PF00498	0.807
LIG_FHA_2	109	115	PF00498	0.825
LIG_FHA_2	308	314	PF00498	0.687
LIG_FHA_2	442	448	PF00498	0.531
LIG_FHA_2	671	677	PF00498	0.821
LIG_FHA_2	731	737	PF00498	0.784
LIG_FHA_2	777	783	PF00498	0.761
LIG_GBD_Chelix_1	633	641	PF00786	0.781
LIG_LIR_Apic_2	382	386	PF02991	0.665
LIG_LIR_Apic_2	546	552	PF02991	0.826
LIG_LIR_Apic_2	750	755	PF02991	0.749
LIG_LIR_Gen_1	340	348	PF02991	0.485
LIG_LIR_Gen_1	356	365	PF02991	0.484
LIG_LIR_Nem_3	32	36	PF02991	0.794
LIG_LIR_Nem_3	356	361	PF02991	0.494
LIG_LIR_Nem_3	818	823	PF02991	0.506
LIG_NRBOX	799	805	PF00104	0.488
LIG_SH2_CRK	26	30	PF00017	0.797
LIG_SH2_CRK	383	387	PF00017	0.585
LIG_SH2_CRK	820	824	PF00017	0.627
LIG_SH2_STAP1	358	362	PF00017	0.477
LIG_SH2_STAP1	496	500	PF00017	0.708
LIG_SH2_STAT5	437	440	PF00017	0.658
LIG_SH2_STAT5	496	499	PF00017	0.704
LIG_SH3_3	104	110	PF00018	0.820
LIG_SH3_3	188	194	PF00018	0.789
LIG_SH3_3	251	257	PF00018	0.690
LIG_SH3_3	264	270	PF00018	0.719
LIG_SH3_3	545	551	PF00018	0.745
LIG_SH3_3	562	568	PF00018	0.768
LIG_SH3_3	644	650	PF00018	0.788
LIG_SH3_3	693	699	PF00018	0.791
LIG_SH3_3	752	758	PF00018	0.623
LIG_SUMO_SIM_anti_2	643	649	PF11976	0.787
LIG_TRAF2_1	206	209	PF00917	0.824
LIG_TRAF2_1	379	382	PF00917	0.641
LIG_TRAF2_1	433	436	PF00917	0.619
LIG_UBA3_1	799	806	PF00899	0.484
MOD_CDC14_SPxK_1	523	526	PF00782	0.807
MOD_CDC14_SPxK_1	557	560	PF00782	0.801
MOD_CDK_SPK_2	144	149	PF00069	0.681
MOD_CDK_SPK_2	197	202	PF00069	0.809
MOD_CDK_SPxK_1	520	526	PF00069	0.787
MOD_CDK_SPxK_1	554	560	PF00069	0.805
MOD_CDK_SPxxK_3	64	71	PF00069	0.806
MOD_CK1_1	147	153	PF00069	0.688
MOD_CK1_1	156	162	PF00069	0.644
MOD_CK1_1	215	221	PF00069	0.769
MOD_CK1_1	256	262	PF00069	0.719
MOD_CK1_1	274	280	PF00069	0.570
MOD_CK1_1	307	313	PF00069	0.735
MOD_CK1_1	314	320	PF00069	0.675
MOD_CK1_1	334	340	PF00069	0.284
MOD_CK1_1	543	549	PF00069	0.715
MOD_CK1_1	566	572	PF00069	0.685
MOD_CK1_1	577	583	PF00069	0.640
MOD_CK1_1	607	613	PF00069	0.760
MOD_CK1_1	616	622	PF00069	0.655
MOD_CK1_1	625	631	PF00069	0.447
MOD_CK1_1	67	73	PF00069	0.752
MOD_CK1_1	671	677	PF00069	0.726
MOD_CK1_1	83	89	PF00069	0.591
MOD_CK1_1	90	96	PF00069	0.718
MOD_CK2_1	108	114	PF00069	0.718
MOD_CK2_1	334	340	PF00069	0.517
MOD_CK2_1	376	382	PF00069	0.631
MOD_CK2_1	442	448	PF00069	0.535
MOD_CK2_1	47	53	PF00069	0.819
MOD_CK2_1	715	721	PF00069	0.770
MOD_CK2_1	730	736	PF00069	0.524
MOD_DYRK1A_RPxSP_1	15	19	PF00069	0.801
MOD_GlcNHglycan	122	125	PF01048	0.747
MOD_GlcNHglycan	203	207	PF01048	0.810
MOD_GlcNHglycan	214	217	PF01048	0.577
MOD_GlcNHglycan	262	265	PF01048	0.757
MOD_GlcNHglycan	273	276	PF01048	0.626
MOD_GlcNHglycan	306	309	PF01048	0.753
MOD_GlcNHglycan	422	425	PF01048	0.660
MOD_GlcNHglycan	455	460	PF01048	0.656
MOD_GlcNHglycan	48	52	PF01048	0.772
MOD_GlcNHglycan	498	501	PF01048	0.711
MOD_GlcNHglycan	5	8	PF01048	0.659
MOD_GlcNHglycan	515	518	PF01048	0.541
MOD_GlcNHglycan	540	543	PF01048	0.822
MOD_GlcNHglycan	585	588	PF01048	0.800
MOD_GlcNHglycan	627	630	PF01048	0.743
MOD_GlcNHglycan	642	645	PF01048	0.598
MOD_GlcNHglycan	662	665	PF01048	0.480
MOD_GlcNHglycan	705	708	PF01048	0.696
MOD_GlcNHglycan	710	713	PF01048	0.717
MOD_GlcNHglycan	730	733	PF01048	0.437
MOD_GlcNHglycan	782	786	PF01048	0.660
MOD_GlcNHglycan	790	793	PF01048	0.481
MOD_GlcNHglycan	82	85	PF01048	0.709
MOD_GSK3_1	11	18	PF00069	0.697
MOD_GSK3_1	152	159	PF00069	0.740
MOD_GSK3_1	179	186	PF00069	0.810
MOD_GSK3_1	189	196	PF00069	0.713
MOD_GSK3_1	256	263	PF00069	0.708
MOD_GSK3_1	274	281	PF00069	0.602
MOD_GSK3_1	300	307	PF00069	0.796
MOD_GSK3_1	314	321	PF00069	0.553
MOD_GSK3_1	438	445	PF00069	0.640
MOD_GSK3_1	496	503	PF00069	0.612
MOD_GSK3_1	534	541	PF00069	0.783
MOD_GSK3_1	573	580	PF00069	0.790
MOD_GSK3_1	600	607	PF00069	0.822
MOD_GSK3_1	616	623	PF00069	0.567
MOD_GSK3_1	62	69	PF00069	0.751
MOD_GSK3_1	625	632	PF00069	0.656
MOD_GSK3_1	660	667	PF00069	0.796
MOD_GSK3_1	703	710	PF00069	0.773
MOD_GSK3_1	715	722	PF00069	0.559
MOD_GSK3_1	76	83	PF00069	0.598
MOD_GSK3_1	767	774	PF00069	0.671
MOD_GSK3_1	777	784	PF00069	0.614
MOD_LATS_1	276	282	PF00433	0.814
MOD_N-GLC_1	420	425	PF02516	0.686
MOD_N-GLC_1	543	548	PF02516	0.712
MOD_N-GLC_1	607	612	PF02516	0.817
MOD_NEK2_1	212	217	PF00069	0.822
MOD_NEK2_1	260	265	PF00069	0.820
MOD_NEK2_1	376	381	PF00069	0.517
MOD_NEK2_1	438	443	PF00069	0.526
MOD_NEK2_1	502	507	PF00069	0.684
MOD_NEK2_1	574	579	PF00069	0.791
MOD_NEK2_1	627	632	PF00069	0.798
MOD_NEK2_1	666	671	PF00069	0.819
MOD_NEK2_2	243	248	PF00069	0.798
MOD_NEK2_2	25	30	PF00069	0.706
MOD_PIKK_1	102	108	PF00454	0.701
MOD_PIKK_1	529	535	PF00454	0.818
MOD_PIKK_1	666	672	PF00454	0.818
MOD_PIKK_1	87	93	PF00454	0.693
MOD_PKA_1	153	159	PF00069	0.791
MOD_PKA_2	100	106	PF00069	0.814
MOD_PKA_2	139	145	PF00069	0.675
MOD_PKA_2	152	158	PF00069	0.677
MOD_PKA_2	179	185	PF00069	0.695
MOD_PKA_2	277	283	PF00069	0.749
MOD_PKA_2	438	444	PF00069	0.642
MOD_PKA_2	513	519	PF00069	0.803
MOD_PKA_2	574	580	PF00069	0.792
MOD_PKA_2	635	641	PF00069	0.778
MOD_PKA_2	657	663	PF00069	0.825
MOD_PKA_2	680	686	PF00069	0.697
MOD_PKA_2	728	734	PF00069	0.791
MOD_Plk_1	334	340	PF00069	0.517
MOD_Plk_4	193	199	PF00069	0.809
MOD_Plk_4	311	317	PF00069	0.774
MOD_Plk_4	622	628	PF00069	0.798
MOD_Plk_4	808	814	PF00069	0.602
MOD_ProDKin_1	108	114	PF00069	0.827
MOD_ProDKin_1	144	150	PF00069	0.683
MOD_ProDKin_1	15	21	PF00069	0.711
MOD_ProDKin_1	197	203	PF00069	0.743
MOD_ProDKin_1	215	221	PF00069	0.815
MOD_ProDKin_1	253	259	PF00069	0.795
MOD_ProDKin_1	520	526	PF00069	0.695
MOD_ProDKin_1	544	550	PF00069	0.748
MOD_ProDKin_1	552	558	PF00069	0.652
MOD_ProDKin_1	607	613	PF00069	0.819
MOD_ProDKin_1	62	68	PF00069	0.756
MOD_ProDKin_1	753	759	PF00069	0.725
MOD_ProDKin_1	76	82	PF00069	0.590
MOD_ProDKin_1	85	91	PF00069	0.700
MOD_SUMO_for_1	386	389	PF00179	0.689
MOD_SUMO_rev_2	236	243	PF00179	0.790
MOD_SUMO_rev_2	423	433	PF00179	0.651
TRG_DiLeu_BaLyEn_6	131	136	PF01217	0.658
TRG_ENDOCYTIC_2	26	29	PF00928	0.798
TRG_ENDOCYTIC_2	352	355	PF00928	0.477
TRG_ENDOCYTIC_2	358	361	PF00928	0.254
TRG_ENDOCYTIC_2	820	823	PF00928	0.625
TRG_ER_diArg_1	152	154	PF00400	0.805
TRG_ER_diArg_1	179	181	PF00400	0.702
TRG_ER_diArg_1	231	234	PF00400	0.784
TRG_ER_diArg_1	348	350	PF00400	0.487
TRG_ER_diArg_1	73	75	PF00400	0.828
TRG_Pf-PMV_PEXEL_1	27	32	PF00026	0.788
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.481
TRG_Pf-PMV_PEXEL_1	451	455	PF00026	0.609
TRG_Pf-PMV_PEXEL_1	746	750	PF00026	0.763
TRG_Pf-PMV_PEXEL_1	801	805	PF00026	0.603
TRG_Pf-PMV_PEXEL_1	821	825	PF00026	0.287

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5F7	Leptomonas seymouri	33%	96%