LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

HMA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
HMA domain-containing protein
Gene product:
Present in the outer mitochondrial membrane proteome 18
Species:
Leishmania braziliensis
UniProt:
A4H6W3_LEIBR
TriTrypDb:
LbrM.12.0500 , LBRM2903_120011300 *
Length:
110

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6W3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6W3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 87 89 PF00675 0.406
CLV_PCSK_KEX2_1 76 78 PF00082 0.389
CLV_PCSK_PC1ET2_1 76 78 PF00082 0.334
DOC_PP1_RVXF_1 21 28 PF00149 0.314
DOC_PP1_RVXF_1 43 50 PF00149 0.327
DOC_USP7_UBL2_3 96 100 PF12436 0.391
DOC_WW_Pin1_4 49 54 PF00397 0.376
DOC_WW_Pin1_4 64 69 PF00397 0.368
DOC_WW_Pin1_4 91 96 PF00397 0.477
LIG_14-3-3_CanoR_1 86 95 PF00244 0.424
LIG_LIR_Gen_1 98 108 PF02991 0.604
LIG_LIR_Nem_3 98 104 PF02991 0.570
LIG_SH3_3 10 16 PF00018 0.461
LIG_SH3_3 58 64 PF00018 0.305
LIG_SH3_3 89 95 PF00018 0.375
LIG_SH3_3 99 105 PF00018 0.361
LIG_TRAF2_1 95 98 PF00917 0.372
LIG_WW_1 105 108 PF00397 0.420
MOD_CDK_SPK_2 91 96 PF00069 0.378
MOD_Cter_Amidation 74 77 PF01082 0.328
MOD_GlcNHglycan 2 5 PF01048 0.676
MOD_GlcNHglycan 8 11 PF01048 0.738
MOD_GSK3_1 87 94 PF00069 0.405
MOD_NEK2_1 87 92 PF00069 0.372
MOD_NMyristoyl 1 7 PF02799 0.491
MOD_PIKK_1 87 93 PF00454 0.373
MOD_PKA_2 87 93 PF00069 0.437
MOD_ProDKin_1 49 55 PF00069 0.379
MOD_ProDKin_1 64 70 PF00069 0.363
MOD_ProDKin_1 91 97 PF00069 0.473
MOD_SUMO_for_1 95 98 PF00179 0.372
MOD_SUMO_rev_2 93 102 PF00179 0.354

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6C1 Leptomonas seymouri 88% 81%
A0A0S4JMJ7 Bodo saltans 52% 70%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS