Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H6V6_LEIBR

TriTrypDb:

LbrM.12.0430 , LBRM2903_120009300

Length:

365

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6V6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6V6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	227	229	PF00675	0.534
CLV_NRD_NRD_1	347	349	PF00675	0.555
CLV_NRD_NRD_1	80	82	PF00675	0.621
CLV_PCSK_FUR_1	225	229	PF00082	0.521
CLV_PCSK_KEX2_1	227	229	PF00082	0.534
CLV_PCSK_KEX2_1	347	349	PF00082	0.555
CLV_PCSK_SKI1_1	163	167	PF00082	0.719
CLV_PCSK_SKI1_1	198	202	PF00082	0.604
CLV_PCSK_SKI1_1	271	275	PF00082	0.637
CLV_PCSK_SKI1_1	81	85	PF00082	0.475
DEG_SPOP_SBC_1	151	155	PF00917	0.544
DEG_SPOP_SBC_1	199	203	PF00917	0.551
DOC_CYCLIN_yClb3_PxF_3	356	362	PF00134	0.550
DOC_MAPK_gen_1	271	279	PF00069	0.507
DOC_MAPK_MEF2A_6	93	102	PF00069	0.516
DOC_PP1_RVXF_1	161	167	PF00149	0.516
DOC_PP4_FxxP_1	297	300	PF00568	0.557
DOC_PP4_FxxP_1	86	89	PF00568	0.633
DOC_USP7_MATH_1	101	105	PF00917	0.525
DOC_USP7_MATH_1	122	126	PF00917	0.773
DOC_USP7_MATH_1	152	156	PF00917	0.574
DOC_USP7_MATH_1	199	203	PF00917	0.618
DOC_USP7_MATH_1	301	305	PF00917	0.553
DOC_WW_Pin1_4	114	119	PF00397	0.610
DOC_WW_Pin1_4	134	139	PF00397	0.616
DOC_WW_Pin1_4	176	181	PF00397	0.720
DOC_WW_Pin1_4	228	233	PF00397	0.710
DOC_WW_Pin1_4	279	284	PF00397	0.787
DOC_WW_Pin1_4	317	322	PF00397	0.703
DOC_WW_Pin1_4	336	341	PF00397	0.495
DOC_WW_Pin1_4	352	357	PF00397	0.673
DOC_WW_Pin1_4	55	60	PF00397	0.585
DOC_WW_Pin1_4	64	69	PF00397	0.571
DOC_WW_Pin1_4	85	90	PF00397	0.719
LIG_14-3-3_CanoR_1	176	180	PF00244	0.745
LIG_14-3-3_CanoR_1	198	208	PF00244	0.606
LIG_14-3-3_CanoR_1	81	86	PF00244	0.478
LIG_BIR_II_1	1	5	PF00653	0.504
LIG_BIR_III_2	12	16	PF00653	0.533
LIG_BRCT_BRCA1_1	214	218	PF00533	0.511
LIG_BRCT_BRCA1_1	293	297	PF00533	0.677
LIG_EH_1	294	298	PF12763	0.615
LIG_eIF4E_1	159	165	PF01652	0.594
LIG_EVH1_2	360	364	PF00568	0.552
LIG_FHA_1	330	336	PF00498	0.545
LIG_FHA_2	337	343	PF00498	0.692
LIG_IRF3_LxIS_1	35	42	PF10401	0.656
LIG_LIR_Apic_2	294	300	PF02991	0.546
LIG_LIR_Apic_2	84	89	PF02991	0.648
LIG_LIR_Gen_1	26	36	PF02991	0.564
LIG_LIR_Gen_1	72	83	PF02991	0.690
LIG_LIR_Nem_3	153	159	PF02991	0.532
LIG_LIR_Nem_3	26	31	PF02991	0.603
LIG_LIR_Nem_3	72	78	PF02991	0.690
LIG_MYND_1	296	300	PF01753	0.552
LIG_SH2_CRK	65	69	PF00017	0.678
LIG_SH2_GRB2like	129	132	PF00017	0.652
LIG_SH2_SRC	70	73	PF00017	0.554
LIG_SH2_STAP1	129	133	PF00017	0.517
LIG_SH2_STAT5	312	315	PF00017	0.599
LIG_SH2_STAT5	70	73	PF00017	0.566
LIG_SH3_3	142	148	PF00018	0.618
LIG_SH3_3	230	236	PF00018	0.552
LIG_SH3_3	280	286	PF00018	0.721
LIG_SH3_3	290	296	PF00018	0.564
LIG_SH3_3	354	360	PF00018	0.554
LIG_SUMO_SIM_par_1	334	339	PF11976	0.636
MOD_CDC14_SPxK_1	179	182	PF00782	0.721
MOD_CDK_SPK_2	114	119	PF00069	0.555
MOD_CDK_SPK_2	64	69	PF00069	0.593
MOD_CDK_SPxK_1	176	182	PF00069	0.718
MOD_CK1_1	114	120	PF00069	0.695
MOD_CK1_1	125	131	PF00069	0.666
MOD_CK1_1	155	161	PF00069	0.521
MOD_CK1_1	2	8	PF00069	0.670
MOD_CK1_1	305	311	PF00069	0.544
MOD_CK1_1	355	361	PF00069	0.551
MOD_CK1_1	51	57	PF00069	0.614
MOD_CK2_1	301	307	PF00069	0.553
MOD_CK2_1	49	55	PF00069	0.682
MOD_GlcNHglycan	114	117	PF01048	0.596
MOD_GlcNHglycan	51	54	PF01048	0.776
MOD_GSK3_1	1	8	PF00069	0.656
MOD_GSK3_1	108	115	PF00069	0.532
MOD_GSK3_1	134	141	PF00069	0.756
MOD_GSK3_1	147	154	PF00069	0.645
MOD_GSK3_1	171	178	PF00069	0.675
MOD_GSK3_1	23	30	PF00069	0.514
MOD_GSK3_1	301	308	PF00069	0.636
MOD_GSK3_1	351	358	PF00069	0.719
MOD_GSK3_1	45	52	PF00069	0.669
MOD_GSK3_1	81	88	PF00069	0.505
MOD_N-GLC_1	302	307	PF02516	0.550
MOD_NEK2_1	1	6	PF00069	0.516
MOD_NEK2_1	112	117	PF00069	0.555
MOD_NEK2_1	172	177	PF00069	0.539
MOD_NEK2_1	277	282	PF00069	0.686
MOD_NEK2_1	39	44	PF00069	0.756
MOD_NEK2_1	49	54	PF00069	0.642
MOD_NEK2_2	122	127	PF00069	0.615
MOD_PIKK_1	209	215	PF00454	0.658
MOD_PIKK_1	355	361	PF00454	0.551
MOD_PKA_1	81	87	PF00069	0.481
MOD_PKA_2	175	181	PF00069	0.742
MOD_Plk_1	305	311	PF00069	0.544
MOD_Plk_4	101	107	PF00069	0.537
MOD_Plk_4	284	290	PF00069	0.548
MOD_Plk_4	81	87	PF00069	0.494
MOD_ProDKin_1	114	120	PF00069	0.608
MOD_ProDKin_1	134	140	PF00069	0.642
MOD_ProDKin_1	176	182	PF00069	0.723
MOD_ProDKin_1	228	234	PF00069	0.714
MOD_ProDKin_1	279	285	PF00069	0.789
MOD_ProDKin_1	317	323	PF00069	0.705
MOD_ProDKin_1	336	342	PF00069	0.494
MOD_ProDKin_1	352	358	PF00069	0.673
MOD_ProDKin_1	55	61	PF00069	0.587
MOD_ProDKin_1	64	70	PF00069	0.568
MOD_ProDKin_1	85	91	PF00069	0.721
TRG_DiLeu_BaEn_1	160	165	PF01217	0.680
TRG_DiLeu_BaEn_1	264	269	PF01217	0.485
TRG_DiLeu_BaEn_2	161	167	PF01217	0.516
TRG_DiLeu_LyEn_5	160	165	PF01217	0.680
TRG_ER_diArg_1	224	227	PF00400	0.569
TRG_ER_diArg_1	346	348	PF00400	0.548

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H6K7	Leishmania donovani	62%	89%
E9AGC8	Leishmania infantum	62%	89%
E9ANW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	93%
Q4QGQ2	Leishmania major	58%	100%