LeishMANIAdb
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Putative proteasome regulatory ATPase subunittcc1l8.3

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative proteasome regulatory ATPase subunittcc1l8.3
Gene product:
proteasome regulatory ATPase subunittcc1l8.3, putative
Species:
Leishmania braziliensis
UniProt:
A4H6T6_LEIBR
TriTrypDb:
LbrM.12.0230 , LBRM2903_120007200 *
Length:
361

Annotations

LeishMANIAdb annotations

A large and likely artifical grouping of protease domain carrying proteins related to proteasomal proteases. Only a tiny subgroup (the AFG3-related mitochondrail proteins) seem to have a TM segment.. Localization: Cytoplasmic (by homology) / Mitochondrial (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 4
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 10
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0000502 proteasome complex 3 10
GO:0005737 cytoplasm 2 11
GO:0032991 protein-containing complex 1 11
GO:0110165 cellular anatomical entity 1 11
GO:0140535 intracellular protein-containing complex 2 10
GO:1902494 catalytic complex 2 10
GO:1905368 peptidase complex 3 10
GO:1905369 endopeptidase complex 4 10
GO:0008540 proteasome regulatory particle, base subcomplex 2 1

Expansion

Sequence features

A4H6T6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6T6

Function

Biological processes
Term Name Level Count
GO:0006807 nitrogen compound metabolic process 2 11
GO:0008152 metabolic process 1 11
GO:0009056 catabolic process 2 11
GO:0009057 macromolecule catabolic process 4 11
GO:0019538 protein metabolic process 3 11
GO:0030163 protein catabolic process 4 11
GO:0043170 macromolecule metabolic process 3 11
GO:0044238 primary metabolic process 2 11
GO:0071704 organic substance metabolic process 2 11
GO:1901564 organonitrogen compound metabolic process 3 11
GO:1901565 organonitrogen compound catabolic process 4 11
GO:1901575 organic substance catabolic process 3 11
GO:0006508 proteolysis 4 1
GO:0006511 ubiquitin-dependent protein catabolic process 7 1
GO:0009987 cellular process 1 1
GO:0010498 proteasomal protein catabolic process 5 1
GO:0019941 modification-dependent protein catabolic process 6 1
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6 1
GO:0043632 modification-dependent macromolecule catabolic process 5 1
GO:0044237 cellular metabolic process 2 1
GO:0044248 cellular catabolic process 3 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0044265 obsolete cellular macromolecule catabolic process 4 1
GO:0051603 proteolysis involved in protein catabolic process 5 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 11
GO:0003824 catalytic activity 1 11
GO:0005488 binding 1 11
GO:0005524 ATP binding 5 11
GO:0016462 pyrophosphatase activity 5 11
GO:0016787 hydrolase activity 2 11
GO:0016817 hydrolase activity, acting on acid anhydrides 3 11
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 11
GO:0016887 ATP hydrolysis activity 7 11
GO:0017076 purine nucleotide binding 4 11
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 11
GO:0030554 adenyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032559 adenyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0036402 proteasome-activating activity 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:0140657 ATP-dependent activity 1 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 207 211 PF00656 0.321
CLV_C14_Caspase3-7 236 240 PF00656 0.319
CLV_C14_Caspase3-7 36 40 PF00656 0.493
CLV_C14_Caspase3-7 87 91 PF00656 0.564
CLV_NRD_NRD_1 186 188 PF00675 0.319
CLV_NRD_NRD_1 270 272 PF00675 0.300
CLV_NRD_NRD_1 280 282 PF00675 0.404
CLV_NRD_NRD_1 329 331 PF00675 0.333
CLV_PCSK_FUR_1 281 285 PF00082 0.391
CLV_PCSK_KEX2_1 215 217 PF00082 0.305
CLV_PCSK_KEX2_1 22 24 PF00082 0.497
CLV_PCSK_KEX2_1 280 282 PF00082 0.404
CLV_PCSK_KEX2_1 283 285 PF00082 0.389
CLV_PCSK_PC1ET2_1 215 217 PF00082 0.300
CLV_PCSK_PC1ET2_1 22 24 PF00082 0.497
CLV_PCSK_PC1ET2_1 283 285 PF00082 0.408
CLV_PCSK_SKI1_1 142 146 PF00082 0.300
CLV_PCSK_SKI1_1 154 158 PF00082 0.300
CLV_PCSK_SKI1_1 190 194 PF00082 0.300
CLV_PCSK_SKI1_1 284 288 PF00082 0.392
DEG_Nend_Nbox_1 1 3 PF02207 0.409
DOC_CYCLIN_RxL_1 280 291 PF00134 0.389
DOC_MAPK_FxFP_2 275 278 PF00069 0.319
DOC_MAPK_gen_1 163 172 PF00069 0.406
DOC_MAPK_gen_1 22 29 PF00069 0.486
DOC_MAPK_gen_1 265 275 PF00069 0.300
DOC_MAPK_gen_1 280 287 PF00069 0.388
DOC_MAPK_gen_1 330 337 PF00069 0.402
DOC_MAPK_MEF2A_6 120 127 PF00069 0.394
DOC_MAPK_MEF2A_6 197 205 PF00069 0.300
DOC_MAPK_MEF2A_6 22 31 PF00069 0.437
DOC_MAPK_MEF2A_6 225 234 PF00069 0.300
DOC_MAPK_MEF2A_6 293 302 PF00069 0.414
DOC_MAPK_MEF2A_6 63 72 PF00069 0.523
DOC_MAPK_RevD_3 201 216 PF00069 0.300
DOC_MAPK_RevD_3 315 331 PF00069 0.300
DOC_PP1_RVXF_1 269 276 PF00149 0.300
DOC_PP1_RVXF_1 281 288 PF00149 0.388
DOC_PP4_FxxP_1 275 278 PF00568 0.300
DOC_USP7_MATH_1 37 41 PF00917 0.449
DOC_USP7_MATH_1 68 72 PF00917 0.467
DOC_USP7_UBL2_3 18 22 PF12436 0.493
DOC_USP7_UBL2_3 63 67 PF12436 0.475
DOC_WW_Pin1_4 294 299 PF00397 0.412
LIG_14-3-3_CanoR_1 56 62 PF00244 0.484
LIG_BRCT_BRCA1_1 201 205 PF00533 0.345
LIG_BRCT_BRCA1_1 50 54 PF00533 0.555
LIG_FHA_1 153 159 PF00498 0.315
LIG_FHA_1 242 248 PF00498 0.311
LIG_FHA_1 5 11 PF00498 0.460
LIG_FHA_1 90 96 PF00498 0.519
LIG_FHA_2 103 109 PF00498 0.425
LIG_FHA_2 219 225 PF00498 0.300
LIG_FHA_2 234 240 PF00498 0.334
LIG_FHA_2 305 311 PF00498 0.319
LIG_FHA_2 350 356 PF00498 0.514
LIG_LIR_Apic_2 274 278 PF02991 0.300
LIG_LIR_Gen_1 103 114 PF02991 0.419
LIG_LIR_Gen_1 168 177 PF02991 0.319
LIG_LIR_Gen_1 253 264 PF02991 0.300
LIG_LIR_Gen_1 51 61 PF02991 0.462
LIG_LIR_Nem_3 103 109 PF02991 0.427
LIG_LIR_Nem_3 168 172 PF02991 0.319
LIG_LIR_Nem_3 253 259 PF02991 0.300
LIG_LIR_Nem_3 342 348 PF02991 0.391
LIG_LIR_Nem_3 354 360 PF02991 0.532
LIG_LIR_Nem_3 51 57 PF02991 0.462
LIG_MLH1_MIPbox_1 50 54 PF16413 0.555
LIG_NRBOX 230 236 PF00104 0.300
LIG_PCNA_yPIPBox_3 225 235 PF02747 0.300
LIG_Pex14_2 177 181 PF04695 0.431
LIG_SH2_CRK 147 151 PF00017 0.319
LIG_SH2_CRK 345 349 PF00017 0.420
LIG_SH2_NCK_1 106 110 PF00017 0.418
LIG_SH2_NCK_1 133 137 PF00017 0.431
LIG_SH2_PTP2 334 337 PF00017 0.394
LIG_SH2_STAT5 305 308 PF00017 0.410
LIG_SH2_STAT5 334 337 PF00017 0.394
LIG_SH2_STAT5 53 56 PF00017 0.464
LIG_SH3_3 120 126 PF00018 0.393
LIG_SH3_3 303 309 PF00018 0.319
LIG_SH3_3 332 338 PF00018 0.396
LIG_SUMO_SIM_anti_2 92 100 PF11976 0.614
LIG_SUMO_SIM_par_1 230 236 PF11976 0.319
LIG_TRAF2_1 17 20 PF00917 0.454
LIG_TRAF2_1 352 355 PF00917 0.415
LIG_TYR_ITIM 104 109 PF00017 0.416
LIG_UBA3_1 57 63 PF00899 0.475
LIG_WW_3 139 143 PF00397 0.405
MOD_CK1_1 211 217 PF00069 0.323
MOD_CK1_1 46 52 PF00069 0.483
MOD_CK2_1 304 310 PF00069 0.319
MOD_CK2_1 349 355 PF00069 0.522
MOD_GlcNHglycan 13 17 PF01048 0.483
MOD_GlcNHglycan 312 315 PF01048 0.327
MOD_GlcNHglycan 45 48 PF01048 0.340
MOD_GSK3_1 349 356 PF00069 0.614
MOD_GSK3_1 91 98 PF00069 0.607
MOD_N-GLC_1 294 299 PF02516 0.412
MOD_N-GLC_1 68 73 PF02516 0.318
MOD_N-GLC_1 96 101 PF02516 0.562
MOD_N-GLC_2 79 81 PF02516 0.262
MOD_NEK2_1 241 246 PF00069 0.314
MOD_NEK2_1 74 79 PF00069 0.558
MOD_NEK2_2 37 42 PF00069 0.433
MOD_PIKK_1 233 239 PF00454 0.319
MOD_PIKK_1 48 54 PF00454 0.563
MOD_PKA_2 162 168 PF00069 0.409
MOD_Plk_1 102 108 PF00069 0.405
MOD_Plk_1 353 359 PF00069 0.660
MOD_Plk_1 68 74 PF00069 0.555
MOD_Plk_1 89 95 PF00069 0.507
MOD_Plk_4 152 158 PF00069 0.316
MOD_Plk_4 165 171 PF00069 0.300
MOD_Plk_4 199 205 PF00069 0.345
MOD_ProDKin_1 294 300 PF00069 0.409
MOD_SUMO_for_1 11 14 PF00179 0.482
MOD_SUMO_for_1 17 20 PF00179 0.437
MOD_SUMO_rev_2 14 24 PF00179 0.495
TRG_DiLeu_BaEn_1 6 11 PF01217 0.537
TRG_ENDOCYTIC_2 106 109 PF00928 0.418
TRG_ENDOCYTIC_2 133 136 PF00928 0.457
TRG_ENDOCYTIC_2 334 337 PF00928 0.394
TRG_ENDOCYTIC_2 345 348 PF00928 0.419
TRG_Pf-PMV_PEXEL_1 180 184 PF00026 0.300
TRG_Pf-PMV_PEXEL_1 229 233 PF00026 0.300

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4E9 Leptomonas seymouri 42% 91%
A0A0N0P5B8 Leptomonas seymouri 40% 81%
A0A0N0P5V2 Leptomonas seymouri 33% 100%
A0A0N0P7K1 Leptomonas seymouri 45% 88%
A0A0N1IGY9 Leptomonas seymouri 99% 87%
A0A0N1IM81 Leptomonas seymouri 49% 82%
A0A0N1PAS8 Leptomonas seymouri 45% 83%
A0A0S4IJE6 Bodo saltans 45% 83%
A0A0S4ITX1 Bodo saltans 42% 81%
A0A0S4IY28 Bodo saltans 45% 100%
A0A0S4JCD0 Bodo saltans 52% 91%
A0A0S4JDU3 Bodo saltans 47% 92%
A0A0S4JSD8 Bodo saltans 88% 91%
A0A0S4KLG9 Bodo saltans 33% 72%
A0A1X0NMZ3 Trypanosomatidae 48% 83%
A0A1X0NNS1 Trypanosomatidae 85% 87%
A0A1X0NT86 Trypanosomatidae 42% 82%
A0A1X0NUX3 Trypanosomatidae 45% 83%
A0A1X0P1T5 Trypanosomatidae 45% 89%
A0A1X0P8T7 Trypanosomatidae 44% 91%
A0A3Q8IJS0 Leishmania donovani 44% 88%
A0A3R7LUG9 Trypanosoma rangeli 42% 82%
A0A3R7N4Y5 Trypanosoma rangeli 45% 89%
A0A3S5H547 Leishmania donovani 44% 91%
A0A3S7WRY0 Leishmania donovani 99% 88%
A0A3S7WSK7 Leishmania donovani 49% 82%
A0A3S7WX14 Leishmania donovani 45% 81%
A0A3S7WX46 Leishmania donovani 45% 83%
A0A3S7X163 Leishmania donovani 36% 68%
A0A422NDS9 Trypanosoma rangeli 45% 83%
A0A422NLD8 Trypanosoma rangeli 48% 83%
A0A422NMN6 Trypanosoma rangeli 44% 91%
A0A422NUD9 Trypanosoma rangeli 88% 91%
A1A0U4 Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) 42% 70%
A3CV35 Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) 48% 88%
A4G0S4 Methanococcus maripaludis (strain C5 / ATCC BAA-1333) 45% 89%
A4H3L6 Leishmania braziliensis 43% 100%
A4H795 Leishmania braziliensis 49% 100%
A4HCA3 Leishmania braziliensis 45% 83%
A4HCA7 Leishmania braziliensis 45% 100%
A4HG81 Leishmania braziliensis 37% 69%
A4HME8 Leishmania braziliensis 33% 100%
A4HPD5 Leishmania braziliensis 38% 68%
A4HPV3 Leishmania braziliensis 45% 100%
A4HVN7 Leishmania infantum 49% 82%
A4HZT4 Leishmania infantum 45% 83%
A4HZT9 Leishmania infantum 45% 81%
A4IE38 Leishmania infantum 44% 88%
A4QE83 Corynebacterium glutamicum (strain R) 37% 69%
A6UQT3 Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB) 47% 89%
A6VHR1 Methanococcus maripaludis (strain C7 / ATCC BAA-1331) 46% 89%
A7I8B8 Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) 48% 83%
A9A916 Methanococcus maripaludis (strain C6 / ATCC BAA-1332) 46% 89%
A9RA82 Papio anubis 38% 74%
B0K657 Thermoanaerobacter sp. (strain X514) 40% 71%
B1VDV2 Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) 38% 67%
B3DRN4 Bifidobacterium longum (strain DJO10A) 37% 69%
B3EX35 Sorex araneus 38% 74%
B4USW8 Otolemur garnettii 38% 74%
B5X3X5 Salmo salar 37% 74%
B6YXR2 Thermococcus onnurineus (strain NA1) 48% 91%
B7GUP3 Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12) 37% 69%
B7NZ88 Oryctolagus cuniculus 38% 74%
B8DTX4 Bifidobacterium animalis subsp. lactis (strain AD011) 39% 69%
B8GGN4 Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) 46% 88%
C3MRF1 Sulfolobus islandicus (strain L.S.2.15 / Lassen #1) 44% 92%
C3MY47 Sulfolobus islandicus (strain M.14.25 / Kamchatka #1) 44% 92%
C3MZI6 Sulfolobus islandicus (strain M.16.27) 44% 92%
C3N7K8 Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1) 44% 92%
C3NFW6 Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2) 44% 92%
C3PGA0 Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 / CN-1) 34% 69%
C4KIR6 Sulfolobus islandicus (strain M.16.4 / Kamchatka #3) 44% 92%
C5A6P8 Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) 49% 91%
C6A7B2 Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219) 39% 69%
C6AHX0 Bifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314) 39% 69%
C7MCZ0 Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 / NCIMB 9860 / 6-10) 38% 68%
C9ZNL6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQC1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 85% 90%
C9ZRM0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 83%
C9ZRM8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 81%
D0A259 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 41% 90%
D0A4A2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 88%
D0A6K9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 83%
D1BS23 Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07) 36% 66%
D1C4U5 Sphaerobacter thermophilus (strain DSM 20745 / S 6022) 43% 74%
D2Q9C6 Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1) 39% 68%
D3R4I7 Bifidobacterium animalis subsp. lactis (strain BB-12) 39% 69%
D4GUJ7 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 46% 89%
E9ACJ9 Leishmania major 44% 100%
E9AG43 Leishmania infantum 44% 91%
E9AGB0 Leishmania infantum 99% 88%
E9AJT7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 91%
E9ANU8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 99% 88%
E9APD3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 49% 82%
E9ATM0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 44% 88%
E9AVN9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 45% 83%
E9AVP4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 45% 81%
E9AZK1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 36% 67%
O04019 Arabidopsis thaliana 43% 85%
O14126 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 38% 82%
O16368 Caenorhabditis elegans 51% 81%
O17071 Caenorhabditis elegans 42% 89%
O18413 Drosophila melanogaster 45% 89%
O23894 Brassica campestris 43% 85%
O26824 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 45% 88%
O28303 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 50% 91%
O42586 Xenopus laevis 44% 89%
O42587 Xenopus laevis 44% 85%
O42931 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 43% 82%
O57940 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 47% 90%
O61577 Strongylocentrotus purpuratus 39% 70%
O64982 Prunus persica 46% 85%
O74445 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 41% 93%
O74894 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 70% 93%
O75449 Homo sapiens 38% 74%
O76371 Caenorhabditis elegans 40% 84%
O88685 Mus musculus 44% 82%
P0DKJ9 Oryza sativa subsp. japonica 43% 85%
P0DKK0 Oryza sativa subsp. japonica 43% 85%
P17980 Homo sapiens 44% 82%
P33297 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 39% 83%
P33298 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 70% 84%
P33299 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 45% 77%
P34123 Dictyostelium discoideum 72% 90%
P34124 Dictyostelium discoideum 47% 90%
P35998 Homo sapiens 45% 83%
P36612 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 50% 81%
P40327 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 48% 83%
P41836 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 44% 90%
P43686 Homo sapiens 73% 86%
P46465 Oryza sativa subsp. japonica 44% 84%
P46466 Oryza sativa subsp. japonica 49% 81%
P46470 Xenopus laevis 46% 78%
P46471 Mus musculus 45% 83%
P46472 Xenopus laevis 45% 83%
P46502 Caenorhabditis elegans 72% 87%
P46507 Manduca sexta 71% 87%
P48601 Drosophila melanogaster 51% 82%
P52917 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 39% 83%
P53549 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 43% 83%
P54775 Mus musculus 73% 86%
P54776 Solanum lycopersicum 43% 85%
P54778 Solanum tuberosum 73% 87%
P54814 Manduca sexta 45% 90%
P62191 Homo sapiens 50% 82%
P62192 Mus musculus 50% 82%
P62193 Rattus norvegicus 50% 82%
P62194 Bos taurus 46% 89%
P62195 Homo sapiens 46% 89%
P62196 Mus musculus 46% 89%
P62197 Sus scrofa 46% 89%
P62198 Rattus norvegicus 46% 89%
P62333 Homo sapiens 42% 93%
P62334 Mus musculus 42% 93%
P62335 Ictidomys tridecemlineatus 42% 93%
P78578 Aspergillus niger 69% 85%
P85200 Helianthus annuus 74% 87%
Q01939 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 45% 89%
Q0IIR9 Xenopus tropicalis 37% 73%
Q0W257 Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) 46% 87%
Q18787 Caenorhabditis elegans 44% 83%
Q1HGK7 Gallus gallus 38% 73%
Q25544 Naegleria fowleri 45% 87%
Q2FQ56 Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) 51% 88%
Q2KIW6 Bos taurus 42% 93%
Q3T030 Bos taurus 73% 86%
Q41365 Spinacia oleracea 46% 85%
Q4JVP5 Corynebacterium jeikeium (strain K411) 40% 70%
Q4Q0X8 Leishmania major 44% 100%
Q4Q2K9 Leishmania major 30% 67%
Q4QBT5 Leishmania major 45% 100%
Q4QBU0 Leishmania major 45% 100%
Q4QG45 Leishmania major 49% 100%
Q4QGS2 Leishmania major 99% 100%
Q4R407 Macaca fascicularis 38% 74%
Q4R4R0 Macaca fascicularis 45% 83%
Q4R7L3 Macaca fascicularis 73% 86%
Q54PJ1 Dictyostelium discoideum 42% 92%
Q54PN7 Dictyostelium discoideum 43% 86%
Q55BV5 Dictyostelium discoideum 51% 82%
Q58576 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 49% 84%
Q5E9F9 Bos taurus 45% 83%
Q5JHS5 Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) 51% 91%
Q5R8D7 Pongo abelii 44% 83%
Q5RII9 Danio rerio 38% 74%
Q5UT56 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) 49% 88%
Q5XIK7 Rattus norvegicus 38% 74%
Q63347 Rattus norvegicus 44% 83%
Q63569 Rattus norvegicus 44% 82%
Q63570 Rattus norvegicus 73% 86%
Q6E0V2 Rattus norvegicus 37% 74%
Q6LWR0 Methanococcus maripaludis (strain S2 / LL) 46% 89%
Q6NH92 Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) 38% 71%
Q86JA1 Dictyostelium discoideum 47% 84%
Q8FTE3 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 37% 69%
Q8G3G6 Bifidobacterium longum (strain NCC 2705) 37% 69%
Q8K0T4 Mus musculus 39% 74%
Q8NQD8 Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) 37% 69%
Q8PY58 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) 45% 86%
Q8SQI9 Encephalitozoon cuniculi (strain GB-M1) 67% 93%
Q8SQK0 Encephalitozoon cuniculi (strain GB-M1) 47% 92%
Q8SR13 Encephalitozoon cuniculi (strain GB-M1) 41% 90%
Q8SRH0 Encephalitozoon cuniculi (strain GB-M1) 49% 85%
Q8TI88 Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) 45% 86%
Q8TX03 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 49% 83%
Q8U4H3 Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) 47% 91%
Q90732 Gallus gallus 49% 82%
Q94BQ2 Arabidopsis thaliana 44% 86%
Q975U2 Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) 46% 92%
Q980M1 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) 44% 92%
Q9BW62 Homo sapiens 38% 74%
Q9C5U3 Arabidopsis thaliana 44% 86%
Q9HNP9 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 47% 88%
Q9HRW6 Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) 44% 89%
Q9MAK9 Arabidopsis thaliana 43% 90%
Q9PUL2 Xenopus laevis 37% 74%
Q9SEI2 Arabidopsis thaliana 43% 85%
Q9SEI3 Arabidopsis thaliana 43% 90%
Q9SEI4 Arabidopsis thaliana 74% 88%
Q9SL67 Arabidopsis thaliana 49% 81%
Q9SSB4 Arabidopsis thaliana 45% 78%
Q9SSB5 Arabidopsis thaliana 46% 85%
Q9SZD4 Arabidopsis thaliana 49% 81%
Q9V287 Pyrococcus abyssi (strain GE5 / Orsay) 48% 91%
Q9XTT9 Caenorhabditis elegans 46% 87%
Q9YAC7 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 47% 88%
V5AV12 Trypanosoma cruzi 48% 83%
V5B5D2 Trypanosoma cruzi 33% 73%
V5B5X1 Trypanosoma cruzi 45% 83%
V5B5X6 Trypanosoma cruzi 42% 82%
V5BKL6 Trypanosoma cruzi 44% 89%
V5BSS5 Trypanosoma cruzi 44% 91%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS