LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H6T2_LEIBR
TriTrypDb:
LbrM.12.0190 , LBRM2903_120006700 *
Length:
427

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6T2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6T2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 333 337 PF00656 0.501
CLV_NRD_NRD_1 18 20 PF00675 0.448
CLV_PCSK_FUR_1 16 20 PF00082 0.447
CLV_PCSK_KEX2_1 16 18 PF00082 0.454
CLV_PCSK_SKI1_1 100 104 PF00082 0.411
CLV_PCSK_SKI1_1 122 126 PF00082 0.377
CLV_PCSK_SKI1_1 26 30 PF00082 0.385
DEG_COP1_1 186 195 PF00400 0.520
DEG_SPOP_SBC_1 60 64 PF00917 0.552
DOC_CDC14_PxL_1 149 157 PF14671 0.468
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PD33 Leptomonas seymouri 30% 91%
A0A3S7WRT8 Leishmania donovani 62% 100%
E9AGA6 Leishmania infantum 62% 100%
E9ANU4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 100%
Q4QGS6 Leishmania major 63% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS