Ribonuclease mar1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Ribonuclease mar1

Gene product:

ribonuclease mar1

Species:

Leishmania braziliensis

UniProt:

A4H6S1_LEIBR

TriTrypDb:

LbrM.12.0080 , LBRM2903_120005600

Length:

192

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 15
NetGPI	no	yes: 0, no: 15

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6S1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6S1

PDB structure(s): 1x9g_A , 1xn4_A

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	125	127	PF00082	0.316
CLV_PCSK_KEX2_1	26	28	PF00082	0.318
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.324
CLV_PCSK_PC1ET2_1	26	28	PF00082	0.318
CLV_PCSK_SKI1_1	12	16	PF00082	0.363
CLV_PCSK_SKI1_1	125	129	PF00082	0.385
CLV_PCSK_SKI1_1	182	186	PF00082	0.577
CLV_PCSK_SKI1_1	94	98	PF00082	0.278
DEG_COP1_1	83	92	PF00400	0.464
DOC_MAPK_gen_1	182	192	PF00069	0.467
DOC_MAPK_MEF2A_6	12	20	PF00069	0.461
DOC_MAPK_MEF2A_6	185	192	PF00069	0.452
DOC_USP7_UBL2_3	139	143	PF12436	0.591
DOC_USP7_UBL2_3	178	182	PF12436	0.561
DOC_USP7_UBL2_3	22	26	PF12436	0.417
LIG_14-3-3_CanoR_1	84	92	PF00244	0.562
LIG_Actin_WH2_2	116	133	PF00022	0.417
LIG_Actin_WH2_2	81	99	PF00022	0.527
LIG_BIR_II_1	1	5	PF00653	0.449
LIG_FHA_1	11	17	PF00498	0.461
LIG_FHA_1	50	56	PF00498	0.592
LIG_FHA_1	74	80	PF00498	0.576
LIG_FHA_2	114	120	PF00498	0.557
LIG_FHA_2	157	163	PF00498	0.520
LIG_FHA_2	65	71	PF00498	0.493
LIG_LIR_Gen_1	13	23	PF02991	0.569
LIG_LIR_Gen_1	83	92	PF02991	0.548
LIG_LIR_Nem_3	13	18	PF02991	0.569
LIG_LIR_Nem_3	174	180	PF02991	0.420
LIG_LIR_Nem_3	83	88	PF02991	0.539
LIG_PDZ_Class_2	187	192	PF00595	0.559
LIG_PTB_Apo_2	30	37	PF02174	0.583
LIG_SH2_STAT5	54	57	PF00017	0.489
LIG_SH3_1	185	191	PF00018	0.444
LIG_SH3_3	185	191	PF00018	0.544
LIG_UBA3_1	120	125	PF00899	0.481
MOD_CK2_1	156	162	PF00069	0.492
MOD_CK2_1	64	70	PF00069	0.573
MOD_GSK3_1	133	140	PF00069	0.583
MOD_GSK3_1	156	163	PF00069	0.523
MOD_GSK3_1	6	13	PF00069	0.408
MOD_NEK2_1	10	15	PF00069	0.413
MOD_NEK2_1	148	153	PF00069	0.521
MOD_NEK2_1	64	69	PF00069	0.430
MOD_PIKK_1	133	139	PF00454	0.540
MOD_PKA_2	169	175	PF00069	0.337
MOD_PKA_2	83	89	PF00069	0.557
MOD_Plk_1	80	86	PF00069	0.594
MOD_Plk_4	160	166	PF00069	0.393
MOD_SUMO_for_1	184	187	PF00179	0.440
MOD_SUMO_rev_2	136	145	PF00179	0.583
TRG_DiLeu_BaEn_1	91	96	PF01217	0.442
TRG_NES_CRM1_1	119	132	PF08389	0.563
TRG_Pf-PMV_PEXEL_1	182	186	PF00026	0.455

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P932	Leptomonas seymouri	35%	80%
A0A0N1HWD2	Leptomonas seymouri	79%	100%
A0A0N1I400	Leptomonas seymouri	35%	80%
A0A0N1IAK4	Leptomonas seymouri	37%	92%
A0A0S4IL71	Bodo saltans	49%	98%
A0A0S4IVV9	Bodo saltans	54%	99%
A0A1X0NQH8	Trypanosomatidae	47%	98%
A0A3S5H641	Leishmania donovani	30%	76%
A0A3S5H642	Leishmania donovani	42%	85%
A0A3S5IQS6	Trypanosoma rangeli	44%	98%
A0JME6	Danio rerio	39%	97%
A4H5A0	Leishmania braziliensis	33%	100%
A4H5A2	Leishmania braziliensis	40%	100%
A4HTI1	Leishmania infantum	30%	76%
A4HTI3	Leishmania infantum	42%	85%
A4HV50	Leishmania infantum	86%	100%
B5X0W9	Salmo salar	39%	68%
D0VWV0	Leishmania donovani	86%	100%
E9AMA9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	76%
E9AMB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	70%
E9AMB1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	86%
E9ANT2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
G4YEI5	Phytophthora sojae (strain P6497)	34%	91%
P85094	Mus musculus	38%	93%
Q08C33	Danio rerio	37%	68%
Q32KX0	Bos taurus	36%	94%
Q4QGT7	Leishmania major	85%	100%
Q4QID7	Leishmania major	41%	100%
Q4QID9	Leishmania major	30%	100%
Q4R826	Macaca fascicularis	39%	94%
Q54NZ6	Dictyostelium discoideum	33%	93%
Q54NZ8	Dictyostelium discoideum	32%	93%
Q54RC7	Dictyostelium discoideum	26%	90%
Q54RF0	Dictyostelium discoideum	24%	96%
Q5PQ71	Xenopus laevis	40%	94%
Q5RC03	Pongo abelii	38%	94%
Q5U3Z3	Rattus norvegicus	35%	91%
Q6DF67	Xenopus tropicalis	39%	94%
Q96AB3	Homo sapiens	38%	94%
Q9DCC7	Mus musculus	36%	91%
V5AQ92	Trypanosoma cruzi	54%	100%