LeishMANIAdb
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Mutator family transposase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mutator family transposase
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H6R9_LEIBR
TriTrypDb:
LbrM.12.0060 , LBRM2903_120005400
Length:
107

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6R9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6R9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 46 48 PF00675 0.473
CLV_NRD_NRD_1 7 9 PF00675 0.610
CLV_PCSK_FUR_1 4 8 PF00082 0.649
CLV_PCSK_KEX2_1 20 22 PF00082 0.417
CLV_PCSK_KEX2_1 3 5 PF00082 0.551
CLV_PCSK_KEX2_1 46 48 PF00082 0.473
CLV_PCSK_KEX2_1 6 8 PF00082 0.532
CLV_PCSK_PC1ET2_1 20 22 PF00082 0.483
CLV_PCSK_PC1ET2_1 3 5 PF00082 0.606
CLV_PCSK_PC1ET2_1 6 8 PF00082 0.579
CLV_PCSK_SKI1_1 33 37 PF00082 0.530
CLV_PCSK_SKI1_1 69 73 PF00082 0.550
CLV_PCSK_SKI1_1 8 12 PF00082 0.665
DEG_APCC_DBOX_1 32 40 PF00400 0.606
DOC_PP2B_LxvP_1 102 105 PF13499 0.470
DOC_USP7_MATH_1 89 93 PF00917 0.504
DOC_WW_Pin1_4 23 28 PF00397 0.569
DOC_WW_Pin1_4 69 74 PF00397 0.602
LIG_APCC_ABBA_1 81 86 PF00400 0.441
LIG_APCC_ABBA_1 91 96 PF00400 0.330
LIG_BRCT_BRCA1_1 91 95 PF00533 0.435
LIG_FHA_1 7 13 PF00498 0.585
LIG_FHA_1 75 81 PF00498 0.431
LIG_MLH1_MIPbox_1 91 95 PF16413 0.435
LIG_SH2_CRK 53 57 PF00017 0.552
LIG_SH2_SRC 23 26 PF00017 0.527
LIG_SH2_SRC 84 87 PF00017 0.508
LIG_SH2_STAP1 44 48 PF00017 0.583
LIG_SH2_STAT5 84 87 PF00017 0.508
LIG_SH2_STAT5 94 97 PF00017 0.482
LIG_SUMO_SIM_par_1 99 106 PF11976 0.479
LIG_WRC_WIRS_1 68 73 PF05994 0.603
LIG_WW_1 37 40 PF00397 0.610
MOD_CK1_1 74 80 PF00069 0.564
MOD_CK2_1 55 61 PF00069 0.495
MOD_GlcNHglycan 40 43 PF01048 0.567
MOD_GSK3_1 38 45 PF00069 0.511
MOD_GSK3_1 67 74 PF00069 0.503
MOD_NEK2_2 89 94 PF00069 0.432
MOD_PKA_1 6 12 PF00069 0.680
MOD_PKA_2 6 12 PF00069 0.587
MOD_Plk_4 89 95 PF00069 0.424
MOD_ProDKin_1 23 29 PF00069 0.572
MOD_ProDKin_1 69 75 PF00069 0.599
TRG_DiLeu_BaEn_1 86 91 PF01217 0.375
TRG_ENDOCYTIC_2 53 56 PF00928 0.552
TRG_ENDOCYTIC_2 84 87 PF00928 0.513

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3B4 Leptomonas seymouri 78% 100%
A0A1X0NM04 Trypanosomatidae 34% 100%
A0A3Q8IHL3 Leishmania donovani 89% 100%
A0A422N6I2 Trypanosoma rangeli 39% 100%
C9ZQD7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AGA3 Leishmania infantum 89% 100%
E9ANT0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4QGT9 Leishmania major 88% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS