Mitochondrial 28S ribosomal protein S29

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Mitochondrial SSU ribosomal protein 29, putative

Species:

Leishmania braziliensis

UniProt:

A4H6R8_LEIBR

TriTrypDb:

LbrM.12.0050 , LBRM2903_120005300

Length:

498

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	11
GO:0005840	ribosome	5	11
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12
GO:0000314	organellar small ribosomal subunit	5	1
GO:0005737	cytoplasm	2	1
GO:0005763	mitochondrial small ribosomal subunit	3	1
GO:0015935	small ribosomal subunit	4	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0044391	ribosomal subunit	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0098798	mitochondrial protein-containing complex	2	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A4H6R8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6R8

PDB structure(s): 7ane_r

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	1
GO:0005198	structural molecule activity	1	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	199	203	PF00656	0.328
CLV_C14_Caspase3-7	21	25	PF00656	0.470
CLV_C14_Caspase3-7	310	314	PF00656	0.526
CLV_NRD_NRD_1	111	113	PF00675	0.392
CLV_NRD_NRD_1	438	440	PF00675	0.376
CLV_NRD_NRD_1	481	483	PF00675	0.446
CLV_NRD_NRD_1	6	8	PF00675	0.564
CLV_PCSK_KEX2_1	470	472	PF00082	0.470
CLV_PCSK_KEX2_1	481	483	PF00082	0.317
CLV_PCSK_PC1ET2_1	470	472	PF00082	0.473
CLV_PCSK_PC7_1	466	472	PF00082	0.493
CLV_PCSK_SKI1_1	107	111	PF00082	0.366
CLV_PCSK_SKI1_1	136	140	PF00082	0.467
CLV_PCSK_SKI1_1	155	159	PF00082	0.166
CLV_PCSK_SKI1_1	205	209	PF00082	0.328
CLV_PCSK_SKI1_1	216	220	PF00082	0.328
CLV_PCSK_SKI1_1	267	271	PF00082	0.413
CLV_PCSK_SKI1_1	306	310	PF00082	0.584
CLV_PCSK_SKI1_1	341	345	PF00082	0.402
CLV_PCSK_SKI1_1	359	363	PF00082	0.275
CLV_PCSK_SKI1_1	410	414	PF00082	0.399
CLV_PCSK_SKI1_1	43	47	PF00082	0.495
CLV_Separin_Metazoa	324	328	PF03568	0.410
DEG_APCC_DBOX_1	204	212	PF00400	0.475
DEG_APCC_DBOX_1	409	417	PF00400	0.289
DEG_Nend_UBRbox_1	1	4	PF02207	0.547
DOC_AGCK_PIF_2	404	409	PF00069	0.389
DOC_CYCLIN_RxL_1	213	223	PF00134	0.358
DOC_CYCLIN_yCln2_LP_2	100	103	PF00134	0.475
DOC_MAPK_FxFP_2	297	300	PF00069	0.328
DOC_MAPK_gen_1	167	176	PF00069	0.328
DOC_MAPK_gen_1	277	285	PF00069	0.334
DOC_MAPK_gen_1	439	446	PF00069	0.386
DOC_MAPK_MEF2A_6	167	176	PF00069	0.344
DOC_MAPK_MEF2A_6	261	268	PF00069	0.341
DOC_MAPK_MEF2A_6	277	285	PF00069	0.284
DOC_MAPK_NFAT4_5	169	177	PF00069	0.363
DOC_PP1_RVXF_1	330	336	PF00149	0.378
DOC_PP1_RVXF_1	441	447	PF00149	0.391
DOC_PP2B_LxvP_1	100	103	PF13499	0.475
DOC_PP4_FxxP_1	198	201	PF00568	0.328
DOC_PP4_FxxP_1	297	300	PF00568	0.328
DOC_PP4_FxxP_1	395	398	PF00568	0.481
DOC_SPAK_OSR1_1	414	418	PF12202	0.349
DOC_USP7_MATH_1	134	138	PF00917	0.548
DOC_USP7_MATH_1	150	154	PF00917	0.363
DOC_USP7_MATH_1	488	492	PF00917	0.641
DOC_WW_Pin1_4	224	229	PF00397	0.328
LIG_14-3-3_CanoR_1	112	121	PF00244	0.478
LIG_14-3-3_CanoR_1	133	139	PF00244	0.528
LIG_14-3-3_CanoR_1	169	175	PF00244	0.217
LIG_14-3-3_CanoR_1	261	265	PF00244	0.328
LIG_14-3-3_CanoR_1	306	312	PF00244	0.465
LIG_14-3-3_CanoR_1	332	336	PF00244	0.358
LIG_14-3-3_CanoR_1	377	383	PF00244	0.486
LIG_BRCT_BRCA1_1	433	437	PF00533	0.368
LIG_deltaCOP1_diTrp_1	186	189	PF00928	0.336
LIG_deltaCOP1_diTrp_1	286	291	PF00928	0.344
LIG_FHA_1	171	177	PF00498	0.338
LIG_FHA_1	219	225	PF00498	0.223
LIG_FHA_1	276	282	PF00498	0.449
LIG_FHA_1	49	55	PF00498	0.542
LIG_FHA_2	181	187	PF00498	0.328
LIG_FHA_2	208	214	PF00498	0.421
LIG_FHA_2	225	231	PF00498	0.201
LIG_FHA_2	308	314	PF00498	0.493
LIG_FHA_2	355	361	PF00498	0.361
LIG_FHA_2	369	375	PF00498	0.449
LIG_FHA_2	403	409	PF00498	0.520
LIG_Integrin_isoDGR_2	140	142	PF01839	0.542
LIG_IRF3_LxIS_1	171	177	PF10401	0.223
LIG_LIR_Apic_2	186	190	PF02991	0.328
LIG_LIR_Apic_2	294	300	PF02991	0.329
LIG_LIR_Apic_2	393	398	PF02991	0.480
LIG_LIR_Apic_2	57	61	PF02991	0.436
LIG_LIR_Gen_1	286	294	PF02991	0.344
LIG_LIR_Gen_1	368	378	PF02991	0.562
LIG_LIR_Gen_1	70	78	PF02991	0.410
LIG_LIR_Nem_3	286	291	PF02991	0.344
LIG_LIR_Nem_3	358	364	PF02991	0.389
LIG_LIR_Nem_3	368	373	PF02991	0.447
LIG_LIR_Nem_3	383	388	PF02991	0.392
LIG_LIR_Nem_3	393	399	PF02991	0.394
LIG_LIR_Nem_3	402	407	PF02991	0.391
LIG_LIR_Nem_3	408	412	PF02991	0.399
LIG_LIR_Nem_3	70	74	PF02991	0.430
LIG_PCNA_yPIPBox_3	82	96	PF02747	0.408
LIG_Pex14_1	465	469	PF04695	0.411
LIG_PTB_Apo_2	372	379	PF02174	0.558
LIG_SH2_CRK	14	18	PF00017	0.431
LIG_SH2_NCK_1	58	62	PF00017	0.432
LIG_SH2_SRC	58	61	PF00017	0.438
LIG_SH2_STAP1	407	411	PF00017	0.455
LIG_SH2_STAP1	433	437	PF00017	0.488
LIG_SH2_STAT3	111	114	PF00017	0.495
LIG_SH2_STAT5	175	178	PF00017	0.328
LIG_SH2_STAT5	22	25	PF00017	0.344
LIG_SH2_STAT5	477	480	PF00017	0.438
LIG_SH2_STAT5	78	81	PF00017	0.343
LIG_SH2_STAT5	88	91	PF00017	0.362
LIG_SH3_2	387	392	PF14604	0.492
LIG_SH3_3	100	106	PF00018	0.400
LIG_SH3_3	323	329	PF00018	0.413
LIG_SH3_3	384	390	PF00018	0.472
LIG_SUMO_SIM_par_1	281	286	PF11976	0.348
LIG_SUMO_SIM_par_1	397	402	PF11976	0.425
LIG_WRPW_2	361	364	PF00400	0.398
MOD_CK1_1	153	159	PF00069	0.474
MOD_CK1_1	292	298	PF00069	0.344
MOD_CK1_1	331	337	PF00069	0.384
MOD_CK1_1	368	374	PF00069	0.576
MOD_CK2_1	180	186	PF00069	0.328
MOD_CK2_1	207	213	PF00069	0.449
MOD_CK2_1	368	374	PF00069	0.507
MOD_CK2_1	378	384	PF00069	0.440
MOD_CK2_1	402	408	PF00069	0.504
MOD_CK2_1	432	438	PF00069	0.375
MOD_Cter_Amidation	5	8	PF01082	0.438
MOD_GlcNHglycan	152	155	PF01048	0.346
MOD_GlcNHglycan	271	276	PF01048	0.264
MOD_GlcNHglycan	367	370	PF01048	0.475
MOD_GlcNHglycan	418	421	PF01048	0.340
MOD_GSK3_1	170	177	PF00069	0.367
MOD_GSK3_1	271	278	PF00069	0.358
MOD_N-GLC_1	402	407	PF02516	0.511
MOD_N-GLC_1	67	72	PF02516	0.549
MOD_NEK2_1	174	179	PF00069	0.350
MOD_NEK2_1	207	212	PF00069	0.432
MOD_NEK2_1	304	309	PF00069	0.473
MOD_NEK2_1	342	347	PF00069	0.461
MOD_NEK2_1	352	357	PF00069	0.292
MOD_PKA_1	112	118	PF00069	0.455
MOD_PKA_2	260	266	PF00069	0.328
MOD_PKA_2	331	337	PF00069	0.384
MOD_Plk_1	488	494	PF00069	0.398
MOD_Plk_1	67	73	PF00069	0.543
MOD_Plk_2-3	313	319	PF00069	0.449
MOD_Plk_2-3	402	408	PF00069	0.499
MOD_Plk_4	189	195	PF00069	0.480
MOD_Plk_4	331	337	PF00069	0.389
MOD_Plk_4	391	397	PF00069	0.426
MOD_Plk_4	73	79	PF00069	0.385
MOD_ProDKin_1	224	230	PF00069	0.328
MOD_SUMO_for_1	39	42	PF00179	0.542
MOD_SUMO_rev_2	434	441	PF00179	0.363
MOD_SUMO_rev_2	462	472	PF00179	0.477
TRG_DiLeu_BaEn_2	407	413	PF01217	0.420
TRG_DiLeu_BaLyEn_6	214	219	PF01217	0.223
TRG_ENDOCYTIC_2	409	412	PF00928	0.423
TRG_Pf-PMV_PEXEL_1	216	220	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	241	245	PF00026	0.434

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5D9	Leptomonas seymouri	89%	100%
A0A0S4KHM8	Bodo saltans	64%	99%
A0A1X0NMI2	Trypanosomatidae	74%	100%
A0A3R7K3G1	Trypanosoma rangeli	75%	100%
A0A3S7WRW9	Leishmania donovani	94%	100%
A4HV48	Leishmania infantum	94%	100%
C9ZQD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
E9ANS9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q4QGU0	Leishmania major	94%	100%
V5DE49	Trypanosoma cruzi	75%	100%