Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H6Q7_LEIBR

TriTrypDb:

LbrM.11.1110 , LBRM2903_110019400

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6Q7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6Q7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	137	141	PF00656	0.488
CLV_NRD_NRD_1	14	16	PF00675	0.519
CLV_NRD_NRD_1	143	145	PF00675	0.525
CLV_PCSK_KEX2_1	14	16	PF00082	0.519
CLV_PCSK_KEX2_1	143	145	PF00082	0.525
CLV_PCSK_PC7_1	139	145	PF00082	0.517
CLV_PCSK_SKI1_1	39	43	PF00082	0.509
DEG_Nend_Nbox_1	1	3	PF02207	0.503
DEG_SCF_FBW7_1	73	80	PF00400	0.466
DOC_CKS1_1	183	188	PF01111	0.412
DOC_CKS1_1	74	79	PF01111	0.617
DOC_CYCLIN_yCln2_LP_2	71	77	PF00134	0.537
DOC_PP2B_LxvP_1	71	74	PF13499	0.500
DOC_PP4_FxxP_1	183	186	PF00568	0.409
DOC_USP7_MATH_1	22	26	PF00917	0.459
DOC_WW_Pin1_4	182	187	PF00397	0.408
DOC_WW_Pin1_4	73	78	PF00397	0.618
DOC_WW_Pin1_4	86	91	PF00397	0.519
LIG_14-3-3_CanoR_1	115	125	PF00244	0.487
LIG_14-3-3_CanoR_1	17	22	PF00244	0.480
LIG_FHA_1	103	109	PF00498	0.408
LIG_FHA_1	40	46	PF00498	0.504
LIG_FHA_1	62	68	PF00498	0.615
LIG_FHA_1	74	80	PF00498	0.500
LIG_FHA_1	87	93	PF00498	0.510
LIG_FHA_2	67	73	PF00498	0.454
LIG_LIR_Apic_2	181	186	PF02991	0.395
LIG_LIR_Gen_1	127	136	PF02991	0.426
LIG_LIR_Gen_1	66	75	PF02991	0.595
LIG_LIR_Nem_3	124	128	PF02991	0.436
LIG_LIR_Nem_3	56	62	PF02991	0.638
LIG_LIR_Nem_3	66	71	PF02991	0.515
LIG_LRP6_Inhibitor_1	109	115	PF00058	0.362
LIG_SH3_1	87	93	PF00018	0.634
LIG_SH3_3	49	55	PF00018	0.618
LIG_SH3_3	71	77	PF00018	0.595
LIG_SH3_3	87	93	PF00018	0.481
LIG_TRAF2_1	148	151	PF00917	0.356
LIG_TRFH_1	59	63	PF08558	0.541
MOD_CK1_1	124	130	PF00069	0.469
MOD_GlcNHglycan	118	121	PF01048	0.461
MOD_GlcNHglycan	19	22	PF01048	0.541
MOD_GSK3_1	178	185	PF00069	0.444
MOD_GSK3_1	29	36	PF00069	0.657
MOD_GSK3_1	39	46	PF00069	0.567
MOD_GSK3_1	50	57	PF00069	0.606
MOD_GSK3_1	73	80	PF00069	0.559
MOD_NEK2_1	116	121	PF00069	0.482
MOD_NEK2_1	79	84	PF00069	0.486
MOD_NEK2_2	63	68	PF00069	0.599
MOD_PIKK_1	61	67	PF00454	0.444
MOD_PKB_1	15	23	PF00069	0.614
MOD_PKB_1	31	39	PF00069	0.460
MOD_Plk_1	178	184	PF00069	0.422
MOD_Plk_2-3	96	102	PF00069	0.541
MOD_Plk_4	54	60	PF00069	0.720
MOD_Plk_4	63	69	PF00069	0.557
MOD_ProDKin_1	182	188	PF00069	0.408
MOD_ProDKin_1	73	79	PF00069	0.617
MOD_ProDKin_1	86	92	PF00069	0.514
MOD_SUMO_for_1	103	106	PF00179	0.433
MOD_SUMO_rev_2	147	154	PF00179	0.513
MOD_SUMO_rev_2	172	177	PF00179	0.481
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.494
TRG_ENDOCYTIC_2	128	131	PF00928	0.432
TRG_ENDOCYTIC_2	59	62	PF00928	0.588
TRG_ER_diArg_1	13	15	PF00400	0.510
TRG_ER_diArg_1	143	146	PF00400	0.529
TRG_Pf-PMV_PEXEL_1	143	147	PF00026	0.520
TRG_Pf-PMV_PEXEL_1	175	179	PF00026	0.448

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P412	Leptomonas seymouri	46%	98%
A0A3Q8I940	Leishmania donovani	78%	100%
A4HV41	Leishmania infantum	78%	100%
E9ANS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4QGU7	Leishmania major	76%	100%