Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H6G8_LEIBR

TriTrypDb:

LbrM.11.0200 , LBRM2903_110007200

Length:

132

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

A4H6G8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6G8

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	128	130	PF00675	0.649
CLV_NRD_NRD_1	24	26	PF00675	0.566
CLV_NRD_NRD_1	8	10	PF00675	0.510
CLV_PCSK_KEX2_1	128	130	PF00082	0.637
CLV_PCSK_KEX2_1	24	26	PF00082	0.463
CLV_PCSK_KEX2_1	8	10	PF00082	0.515
CLV_PCSK_SKI1_1	49	53	PF00082	0.448
DEG_Nend_Nbox_1	1	3	PF02207	0.675
DOC_CYCLIN_yCln2_LP_2	52	58	PF00134	0.631
DOC_PP4_FxxP_1	56	59	PF00568	0.634

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJC2	Leptomonas seymouri	91%	100%
A0A0S4JUP5	Bodo saltans	65%	100%
A0A1X0NV45	Trypanosomatidae	79%	100%
A0A3Q8I7X8	Leishmania donovani	98%	100%
A4HUW7	Leishmania infantum	98%	100%
D0A7J2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	70%	100%
E9ANJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4QH30	Leishmania major	98%	100%
V5DT78	Trypanosoma cruzi	73%	100%

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