ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair and recombination helicase protein PIF2, putative

Species:

Leishmania braziliensis

UniProt:

A4H6E9_LEIBR

TriTrypDb:

LbrM.11.0010 , LBRM2903_110021300 , LBRM2903_110021400

Length:

1080

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	12
GO:0110165	cellular anatomical entity	1	12
GO:0005657	replication fork	2	1

Expansion

Sequence features

A4H6E9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6E9

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	12
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006281	DNA repair	5	12
GO:0006310	DNA recombination	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	12
GO:0006974	DNA damage response	4	12
GO:0006996	organelle organization	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016043	cellular component organization	3	12
GO:0032200	telomere organization	6	12
GO:0033554	cellular response to stress	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	12
GO:0051276	chromosome organization	5	12
GO:0051716	cellular response to stimulus	2	12
GO:0071704	organic substance metabolic process	2	12
GO:0071840	cellular component organization or biogenesis	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	148	152	PF00656	0.823
CLV_C14_Caspase3-7	40	44	PF00656	0.715
CLV_C14_Caspase3-7	568	572	PF00656	0.650
CLV_C14_Caspase3-7	770	774	PF00656	0.584
CLV_NRD_NRD_1	1004	1006	PF00675	0.507
CLV_NRD_NRD_1	1009	1011	PF00675	0.533
CLV_NRD_NRD_1	195	197	PF00675	0.649
CLV_NRD_NRD_1	409	411	PF00675	0.343
CLV_NRD_NRD_1	440	442	PF00675	0.328
CLV_NRD_NRD_1	478	480	PF00675	0.419
CLV_NRD_NRD_1	506	508	PF00675	0.391
CLV_NRD_NRD_1	514	516	PF00675	0.449
CLV_NRD_NRD_1	83	85	PF00675	0.705
CLV_NRD_NRD_1	839	841	PF00675	0.531
CLV_PCSK_FUR_1	1007	1011	PF00082	0.419
CLV_PCSK_KEX2_1	1004	1006	PF00082	0.501
CLV_PCSK_KEX2_1	1009	1011	PF00082	0.537
CLV_PCSK_KEX2_1	1025	1027	PF00082	0.557
CLV_PCSK_KEX2_1	195	197	PF00082	0.596
CLV_PCSK_KEX2_1	409	411	PF00082	0.343
CLV_PCSK_KEX2_1	440	442	PF00082	0.343
CLV_PCSK_KEX2_1	478	480	PF00082	0.419
CLV_PCSK_KEX2_1	506	508	PF00082	0.401
CLV_PCSK_KEX2_1	83	85	PF00082	0.626
CLV_PCSK_KEX2_1	96	98	PF00082	0.732
CLV_PCSK_PC1ET2_1	1025	1027	PF00082	0.612
CLV_PCSK_PC1ET2_1	96	98	PF00082	0.735
CLV_PCSK_PC7_1	1005	1011	PF00082	0.556
CLV_PCSK_SKI1_1	1012	1016	PF00082	0.591
CLV_PCSK_SKI1_1	1049	1053	PF00082	0.634
CLV_PCSK_SKI1_1	195	199	PF00082	0.540
CLV_PCSK_SKI1_1	325	329	PF00082	0.546
CLV_PCSK_SKI1_1	359	363	PF00082	0.331
CLV_PCSK_SKI1_1	364	368	PF00082	0.323
CLV_PCSK_SKI1_1	429	433	PF00082	0.360
CLV_PCSK_SKI1_1	662	666	PF00082	0.500
CLV_PCSK_SKI1_1	670	674	PF00082	0.392
CLV_PCSK_SKI1_1	779	783	PF00082	0.525
CLV_PCSK_SKI1_1	817	821	PF00082	0.406
CLV_PCSK_SKI1_1	93	97	PF00082	0.746
DEG_COP1_1	128	136	PF00400	0.531
DEG_Nend_UBRbox_2	1	3	PF02207	0.479
DEG_SPOP_SBC_1	200	204	PF00917	0.441
DEG_SPOP_SBC_1	547	551	PF00917	0.539
DOC_CKS1_1	133	138	PF01111	0.531
DOC_CKS1_1	584	589	PF01111	0.745
DOC_CKS1_1	802	807	PF01111	0.591
DOC_CYCLIN_RxL_1	426	436	PF00134	0.231
DOC_CYCLIN_yClb5_NLxxxL_5	231	237	PF00134	0.587
DOC_CYCLIN_yClb5_NLxxxL_5	819	828	PF00134	0.462
DOC_CYCLIN_yCln2_LP_2	20	26	PF00134	0.407
DOC_CYCLIN_yCln2_LP_2	636	639	PF00134	0.556
DOC_MAPK_DCC_7	728	737	PF00069	0.577
DOC_MAPK_gen_1	1007	1015	PF00069	0.568
DOC_MAPK_gen_1	440	447	PF00069	0.318
DOC_MAPK_gen_1	478	486	PF00069	0.382
DOC_MAPK_gen_1	506	514	PF00069	0.510
DOC_MAPK_gen_1	93	104	PF00069	0.664
DOC_MAPK_gen_1	956	965	PF00069	0.428
DOC_MAPK_HePTP_8	437	449	PF00069	0.385
DOC_MAPK_JIP1_4	808	814	PF00069	0.548
DOC_MAPK_MEF2A_6	206	215	PF00069	0.465
DOC_MAPK_MEF2A_6	440	449	PF00069	0.316
DOC_MAPK_MEF2A_6	478	486	PF00069	0.467
DOC_MAPK_MEF2A_6	506	514	PF00069	0.539
DOC_MAPK_MEF2A_6	743	750	PF00069	0.515
DOC_MAPK_NFAT4_5	479	487	PF00069	0.266
DOC_MAPK_NFAT4_5	743	751	PF00069	0.329
DOC_MAPK_RevD_3	500	516	PF00069	0.307
DOC_PP1_RVXF_1	492	499	PF00149	0.493
DOC_PP1_RVXF_1	514	521	PF00149	0.583
DOC_PP1_SILK_1	859	864	PF00149	0.291
DOC_PP2B_LxvP_1	20	23	PF13499	0.420
DOC_PP2B_LxvP_1	445	448	PF13499	0.210
DOC_PP2B_LxvP_1	636	639	PF13499	0.533
DOC_PP4_FxxP_1	170	173	PF00568	0.768
DOC_PP4_FxxP_1	874	877	PF00568	0.526
DOC_USP7_MATH_1	1055	1059	PF00917	0.585
DOC_USP7_MATH_1	137	141	PF00917	0.814
DOC_USP7_MATH_1	299	303	PF00917	0.569
DOC_USP7_MATH_1	552	556	PF00917	0.635
DOC_USP7_MATH_1	570	574	PF00917	0.788
DOC_USP7_MATH_1	703	707	PF00917	0.736
DOC_USP7_MATH_1	708	712	PF00917	0.698
DOC_USP7_MATH_1	76	80	PF00917	0.686
DOC_USP7_MATH_2	60	66	PF00917	0.489
DOC_USP7_UBL2_3	1025	1029	PF12436	0.480
DOC_USP7_UBL2_3	658	662	PF12436	0.573
DOC_WW_Pin1_4	1074	1079	PF00397	0.664
DOC_WW_Pin1_4	132	137	PF00397	0.736
DOC_WW_Pin1_4	140	145	PF00397	0.593
DOC_WW_Pin1_4	157	162	PF00397	0.679
DOC_WW_Pin1_4	399	404	PF00397	0.473
DOC_WW_Pin1_4	471	476	PF00397	0.346
DOC_WW_Pin1_4	580	585	PF00397	0.792
DOC_WW_Pin1_4	630	635	PF00397	0.431
DOC_WW_Pin1_4	643	648	PF00397	0.470
DOC_WW_Pin1_4	801	806	PF00397	0.566
LIG_14-3-3_CanoR_1	115	122	PF00244	0.789
LIG_14-3-3_CanoR_1	259	266	PF00244	0.495
LIG_14-3-3_CanoR_1	515	519	PF00244	0.520
LIG_14-3-3_CanoR_1	575	584	PF00244	0.755
LIG_14-3-3_CanoR_1	681	690	PF00244	0.664
LIG_14-3-3_CanoR_1	745	751	PF00244	0.478
LIG_14-3-3_CanoR_1	901	909	PF00244	0.291
LIG_Actin_WH2_2	424	442	PF00022	0.328
LIG_Actin_WH2_2	482	499	PF00022	0.505
LIG_Actin_WH2_2	502	517	PF00022	0.243
LIG_APCC_ABBA_1	781	786	PF00400	0.629
LIG_BIR_III_4	298	302	PF00653	0.696
LIG_BRCT_BRCA1_1	456	460	PF00533	0.378
LIG_BRCT_BRCA1_1	473	477	PF00533	0.300
LIG_BRCT_BRCA1_1	516	520	PF00533	0.585
LIG_BRCT_BRCA1_1	710	714	PF00533	0.729
LIG_CtBP_PxDLS_1	511	515	PF00389	0.460
LIG_CtBP_PxDLS_1	638	642	PF00389	0.586
LIG_CtBP_PxDLS_1	915	919	PF00389	0.421
LIG_FHA_1	192	198	PF00498	0.477
LIG_FHA_1	217	223	PF00498	0.550
LIG_FHA_1	380	386	PF00498	0.328
LIG_FHA_1	46	52	PF00498	0.523
LIG_FHA_1	471	477	PF00498	0.504
LIG_FHA_1	580	586	PF00498	0.796
LIG_FHA_1	617	623	PF00498	0.598
LIG_FHA_1	631	637	PF00498	0.445
LIG_FHA_1	646	652	PF00498	0.388
LIG_FHA_1	661	667	PF00498	0.333
LIG_FHA_1	893	899	PF00498	0.446
LIG_FHA_2	105	111	PF00498	0.731
LIG_FHA_2	2	8	PF00498	0.541
LIG_FHA_2	216	222	PF00498	0.616
LIG_FHA_2	223	229	PF00498	0.577
LIG_FHA_2	263	269	PF00498	0.503
LIG_FHA_2	326	332	PF00498	0.498
LIG_FHA_2	549	555	PF00498	0.479
LIG_FHA_2	608	614	PF00498	0.466
LIG_FHA_2	615	621	PF00498	0.476
LIG_FHA_2	788	794	PF00498	0.475
LIG_FHA_2	973	979	PF00498	0.329
LIG_GBD_Chelix_1	318	326	PF00786	0.480
LIG_Integrin_isoDGR_2	885	887	PF01839	0.591
LIG_Integrin_RGD_1	174	176	PF01839	0.697
LIG_IRF3_LxIS_1	395	402	PF10401	0.473
LIG_LIR_Apic_2	167	173	PF02991	0.775
LIG_LIR_Apic_2	871	877	PF02991	0.535
LIG_LIR_Gen_1	414	424	PF02991	0.386
LIG_LIR_Gen_1	430	439	PF02991	0.237
LIG_LIR_Gen_1	457	468	PF02991	0.332
LIG_LIR_Gen_1	73	82	PF02991	0.718
LIG_LIR_Gen_1	793	801	PF02991	0.520
LIG_LIR_Nem_3	243	247	PF02991	0.522
LIG_LIR_Nem_3	414	419	PF02991	0.386
LIG_LIR_Nem_3	430	435	PF02991	0.237
LIG_LIR_Nem_3	457	463	PF02991	0.381
LIG_LIR_Nem_3	73	78	PF02991	0.719
LIG_LIR_Nem_3	793	798	PF02991	0.523
LIG_LIR_Nem_3	866	870	PF02991	0.476
LIG_LIR_Nem_3	904	909	PF02991	0.267
LIG_LYPXL_S_1	732	736	PF13949	0.544
LIG_MYND_1	634	638	PF01753	0.546
LIG_PCNA_yPIPBox_3	478	490	PF02747	0.323
LIG_PCNA_yPIPBox_3	537	548	PF02747	0.635
LIG_PCNA_yPIPBox_3	830	841	PF02747	0.490
LIG_Pex14_1	645	649	PF04695	0.397
LIG_Pex14_2	477	481	PF04695	0.392
LIG_SH2_CRK	416	420	PF00017	0.400
LIG_SH2_SRC	37	40	PF00017	0.474
LIG_SH2_STAP1	28	32	PF00017	0.637
LIG_SH2_STAP1	37	41	PF00017	0.713
LIG_SH2_STAP1	416	420	PF00017	0.385
LIG_SH2_STAP1	864	868	PF00017	0.391
LIG_SH2_STAP1	920	924	PF00017	0.395
LIG_SH2_STAT3	632	635	PF00017	0.349
LIG_SH2_STAT5	350	353	PF00017	0.328
LIG_SH2_STAT5	632	635	PF00017	0.488
LIG_SH2_STAT5	649	652	PF00017	0.421
LIG_SH2_STAT5	671	674	PF00017	0.415
LIG_SH2_STAT5	676	679	PF00017	0.487
LIG_SH2_STAT5	761	764	PF00017	0.569
LIG_SH2_STAT5	850	853	PF00017	0.518
LIG_SH2_STAT5	867	870	PF00017	0.317
LIG_SH2_STAT5	951	954	PF00017	0.381
LIG_SH3_3	130	136	PF00018	0.719
LIG_SH3_3	139	145	PF00018	0.748
LIG_SH3_3	239	245	PF00018	0.576
LIG_SH3_3	263	269	PF00018	0.611
LIG_SH3_3	300	306	PF00018	0.602
LIG_SH3_3	581	587	PF00018	0.787
LIG_SH3_3	728	734	PF00018	0.499
LIG_SH3_3	741	747	PF00018	0.327
LIG_SH3_3	803	809	PF00018	0.456
LIG_SH3_3	874	880	PF00018	0.449
LIG_SH3_3	887	893	PF00018	0.341
LIG_SH3_3	909	915	PF00018	0.261
LIG_SH3_3	954	960	PF00018	0.411
LIG_SH3_3	99	105	PF00018	0.683
LIG_SUMO_SIM_anti_2	2	8	PF11976	0.454
LIG_SUMO_SIM_anti_2	207	212	PF11976	0.524
LIG_SUMO_SIM_anti_2	417	423	PF11976	0.328
LIG_SUMO_SIM_par_1	323	331	PF11976	0.627
LIG_SUMO_SIM_par_1	417	423	PF11976	0.328
LIG_TRAF2_1	65	68	PF00917	0.690
LIG_UBA3_1	1015	1024	PF00899	0.419
LIG_UBA3_1	362	367	PF00899	0.362
LIG_WRC_WIRS_1	661	666	PF05994	0.584
LIG_WRC_WIRS_1	965	970	PF05994	0.490
MOD_CDK_SPxxK_3	157	164	PF00069	0.693
MOD_CDK_SPxxK_3	471	478	PF00069	0.396
MOD_CDK_SPxxK_3	801	808	PF00069	0.585
MOD_CK1_1	1032	1038	PF00069	0.698
MOD_CK1_1	140	146	PF00069	0.602
MOD_CK1_1	166	172	PF00069	0.620
MOD_CK1_1	201	207	PF00069	0.466
MOD_CK1_1	262	268	PF00069	0.566
MOD_CK1_1	425	431	PF00069	0.356
MOD_CK1_1	573	579	PF00069	0.781
MOD_CK1_1	580	586	PF00069	0.670
MOD_CK1_1	684	690	PF00069	0.596
MOD_CK1_1	715	721	PF00069	0.571
MOD_CK1_1	832	838	PF00069	0.489
MOD_CK1_1	964	970	PF00069	0.553
MOD_CK2_1	1	7	PF00069	0.546
MOD_CK2_1	104	110	PF00069	0.624
MOD_CK2_1	215	221	PF00069	0.580
MOD_CK2_1	222	228	PF00069	0.540
MOD_CK2_1	304	310	PF00069	0.649
MOD_CK2_1	314	320	PF00069	0.669
MOD_CK2_1	39	45	PF00069	0.751
MOD_CK2_1	548	554	PF00069	0.745
MOD_CK2_1	607	613	PF00069	0.454
MOD_CK2_1	614	620	PF00069	0.461
MOD_CK2_1	62	68	PF00069	0.717
MOD_CK2_1	721	727	PF00069	0.666
MOD_GlcNHglycan	1057	1060	PF01048	0.691
MOD_GlcNHglycan	139	142	PF01048	0.769
MOD_GlcNHglycan	306	309	PF01048	0.757
MOD_GlcNHglycan	456	459	PF01048	0.370
MOD_GlcNHglycan	577	580	PF01048	0.789
MOD_GlcNHglycan	690	693	PF01048	0.734
MOD_GlcNHglycan	705	708	PF01048	0.497
MOD_GlcNHglycan	710	713	PF01048	0.401
MOD_GlcNHglycan	773	776	PF01048	0.312
MOD_GSK3_1	1	8	PF00069	0.685
MOD_GSK3_1	104	111	PF00069	0.669
MOD_GSK3_1	1055	1062	PF00069	0.434
MOD_GSK3_1	191	198	PF00069	0.536
MOD_GSK3_1	200	207	PF00069	0.374
MOD_GSK3_1	310	317	PF00069	0.721
MOD_GSK3_1	379	386	PF00069	0.288
MOD_GSK3_1	39	46	PF00069	0.641
MOD_GSK3_1	546	553	PF00069	0.705
MOD_GSK3_1	573	580	PF00069	0.592
MOD_GSK3_1	637	644	PF00069	0.495
MOD_GSK3_1	670	677	PF00069	0.460
MOD_GSK3_1	680	687	PF00069	0.547
MOD_GSK3_1	698	705	PF00069	0.554
MOD_GSK3_1	708	715	PF00069	0.684
MOD_GSK3_1	901	908	PF00069	0.489
MOD_GSK3_1	964	971	PF00069	0.500
MOD_GSK3_1	999	1006	PF00069	0.477
MOD_LATS_1	162	168	PF00433	0.529
MOD_N-GLC_1	1065	1070	PF02516	0.528
MOD_N-GLC_1	281	286	PF02516	0.551
MOD_N-GLC_1	712	717	PF02516	0.686
MOD_N-GLC_1	829	834	PF02516	0.439
MOD_NEK2_1	1	6	PF00069	0.702
MOD_NEK2_1	514	519	PF00069	0.327
MOD_NEK2_1	548	553	PF00069	0.558
MOD_NEK2_1	641	646	PF00069	0.604
MOD_NEK2_1	819	824	PF00069	0.414
MOD_NEK2_1	938	943	PF00069	0.412
MOD_NEK2_1	963	968	PF00069	0.428
MOD_NEK2_1	972	977	PF00069	0.413
MOD_NEK2_1	982	987	PF00069	0.410
MOD_NEK2_2	391	396	PF00069	0.413
MOD_NEK2_2	570	575	PF00069	0.778
MOD_NEK2_2	920	925	PF00069	0.393
MOD_PIKK_1	385	391	PF00454	0.448
MOD_PIKK_1	573	579	PF00454	0.737
MOD_PIKK_1	681	687	PF00454	0.644
MOD_PIKK_1	987	993	PF00454	0.574
MOD_PK_1	693	699	PF00069	0.478
MOD_PK_1	857	863	PF00069	0.566
MOD_PKA_1	195	201	PF00069	0.386
MOD_PKA_2	1003	1009	PF00069	0.654
MOD_PKA_2	1055	1061	PF00069	0.674
MOD_PKA_2	114	120	PF00069	0.785
MOD_PKA_2	195	201	PF00069	0.519
MOD_PKA_2	514	520	PF00069	0.503
MOD_PKA_2	593	599	PF00069	0.716
MOD_PKA_2	680	686	PF00069	0.680
MOD_PKA_2	698	704	PF00069	0.451
MOD_Plk_1	1	7	PF00069	0.682
MOD_Plk_1	262	268	PF00069	0.580
MOD_Plk_1	281	287	PF00069	0.578
MOD_Plk_1	37	43	PF00069	0.613
MOD_Plk_1	411	417	PF00069	0.379
MOD_Plk_1	422	428	PF00069	0.268
MOD_Plk_1	570	576	PF00069	0.777
MOD_Plk_1	61	67	PF00069	0.748
MOD_Plk_1	726	732	PF00069	0.569
MOD_Plk_1	793	799	PF00069	0.471
MOD_Plk_1	857	863	PF00069	0.554
MOD_Plk_1	938	944	PF00069	0.437
MOD_Plk_1	982	988	PF00069	0.411
MOD_Plk_2-3	39	45	PF00069	0.489
MOD_Plk_2-3	412	418	PF00069	0.448
MOD_Plk_2-3	62	68	PF00069	0.745
MOD_Plk_4	1	7	PF00069	0.698
MOD_Plk_4	346	352	PF00069	0.337
MOD_Plk_4	357	363	PF00069	0.299
MOD_Plk_4	422	428	PF00069	0.328
MOD_Plk_4	485	491	PF00069	0.414
MOD_Plk_4	637	643	PF00069	0.482
MOD_Plk_4	645	651	PF00069	0.373
MOD_Plk_4	715	721	PF00069	0.608
MOD_Plk_4	832	838	PF00069	0.486
MOD_Plk_4	857	863	PF00069	0.552
MOD_Plk_4	928	934	PF00069	0.440
MOD_Plk_4	968	974	PF00069	0.508
MOD_ProDKin_1	1074	1080	PF00069	0.668
MOD_ProDKin_1	132	138	PF00069	0.736
MOD_ProDKin_1	140	146	PF00069	0.586
MOD_ProDKin_1	157	163	PF00069	0.679
MOD_ProDKin_1	399	405	PF00069	0.473
MOD_ProDKin_1	471	477	PF00069	0.342
MOD_ProDKin_1	580	586	PF00069	0.793
MOD_ProDKin_1	630	636	PF00069	0.436
MOD_ProDKin_1	643	649	PF00069	0.465
MOD_ProDKin_1	801	807	PF00069	0.561
MOD_SUMO_for_1	1030	1033	PF00179	0.429
MOD_SUMO_rev_2	1042	1051	PF00179	0.659
MOD_SUMO_rev_2	317	327	PF00179	0.716
TRG_DiLeu_BaEn_3	753	759	PF01217	0.561
TRG_DiLeu_BaLyEn_6	256	261	PF01217	0.555
TRG_DiLeu_BaLyEn_6	467	472	PF01217	0.533
TRG_ENDOCYTIC_2	190	193	PF00928	0.461
TRG_ENDOCYTIC_2	254	257	PF00928	0.492
TRG_ENDOCYTIC_2	416	419	PF00928	0.405
TRG_ENDOCYTIC_2	733	736	PF00928	0.432
TRG_ENDOCYTIC_2	951	954	PF00928	0.383
TRG_ER_diArg_1	1003	1005	PF00400	0.516
TRG_ER_diArg_1	195	197	PF00400	0.649
TRG_ER_diArg_1	439	441	PF00400	0.343
TRG_ER_diArg_1	477	479	PF00400	0.404
TRG_ER_diArg_1	505	507	PF00400	0.388
TRG_ER_diArg_1	536	539	PF00400	0.382
TRG_ER_diArg_1	742	745	PF00400	0.402
TRG_ER_diArg_1	776	779	PF00400	0.549
TRG_ER_diArg_1	82	84	PF00400	0.662
TRG_NES_CRM1_1	324	335	PF08389	0.357
TRG_NES_CRM1_1	928	939	PF08389	0.438
TRG_NLS_Bipartite_1	1009	1028	PF00514	0.615
TRG_NLS_Bipartite_1	83	100	PF00514	0.778
TRG_NLS_MonoExtC_3	92	97	PF00514	0.782
TRG_NLS_MonoExtN_4	1007	1014	PF00514	0.621
TRG_NLS_MonoExtN_4	90	97	PF00514	0.778
TRG_Pf-PMV_PEXEL_1	259	263	PF00026	0.571
TRG_Pf-PMV_PEXEL_1	364	368	PF00026	0.362
TRG_Pf-PMV_PEXEL_1	429	433	PF00026	0.362

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIS5	Leptomonas seymouri	63%	79%
A0A0S4IUA9	Bodo saltans	38%	100%
A0A1X0NVS9	Trypanosomatidae	44%	100%
A0A3R7MZY3	Trypanosoma rangeli	44%	100%
A0A3S7WRJ2	Leishmania donovani	79%	88%
A4HUU3	Leishmania infantum	80%	71%
D0A7L2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
E9ANH8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	88%
Q384Y0	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	45%	100%
Q4QH48	Leishmania major	79%	100%
V5DSX3	Trypanosoma cruzi	40%	100%