Publication identifier(s): 31356625
GPI-anchored cell surface protease. Broad-spectrum ectoenzyme involved in pathogenesis. Heavily expanded family in all parazitic species.. Localization: Cell surface (experimental)
by homology
Contact email: albert.descoteaux@iaf.inrs.ca
Publication title: The host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole
Publication 1st author(s): Amandine Isnard
Publication Identifier(s): 25826301
Host organism: -1
Interaction detection method(s): protease assay
Interaction type: physical association
Identification method participant A: monoclonal antibody western blot
Identification method participant B: monoclonal antibody western blot
ID(s) interactor A: P05627
ID(s) interactor B: P08148
Taxid interactor A: Mus musculus
Taxid interactor B: Leishmania major
Biological role(s) interactor A: enzyme
Biological role(s) interactor B: enzyme target
Experimental role(s) interactor A: neutral component
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 2 |
Forrest at al. (procyclic) | no | yes: 4 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 51 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 5 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 41, no: 10 |
NetGPI | no | yes: 0, no: 51 |
Term | Name | Level | Count |
---|---|---|---|
GO:0016020 | membrane | 2 | 52 |
GO:0110165 | cellular anatomical entity | 1 | 52 |
GO:0005737 | cytoplasm | 2 | 4 |
GO:0018995 | host cellular component | 2 | 4 |
GO:0033643 | host cell part | 3 | 4 |
GO:0033646 | host intracellular part | 4 | 4 |
GO:0033647 | host intracellular organelle | 5 | 4 |
GO:0033648 | host intracellular membrane-bounded organelle | 6 | 4 |
GO:0042025 | host cell nucleus | 7 | 4 |
Related structures:
AlphaFold database: A4H6E3
Term | Name | Level | Count |
---|---|---|---|
GO:0006508 | proteolysis | 4 | 52 |
GO:0006807 | nitrogen compound metabolic process | 2 | 52 |
GO:0007155 | cell adhesion | 2 | 52 |
GO:0008152 | metabolic process | 1 | 52 |
GO:0009987 | cellular process | 1 | 52 |
GO:0019538 | protein metabolic process | 3 | 52 |
GO:0043170 | macromolecule metabolic process | 3 | 52 |
GO:0044238 | primary metabolic process | 2 | 52 |
GO:0071704 | organic substance metabolic process | 2 | 52 |
GO:1901564 | organonitrogen compound metabolic process | 3 | 52 |
GO:0009966 | regulation of signal transduction | 4 | 4 |
GO:0010646 | regulation of cell communication | 4 | 4 |
GO:0010749 | regulation of nitric oxide mediated signal transduction | 6 | 4 |
GO:0023051 | regulation of signaling | 3 | 4 |
GO:0035821 | modulation of process of another organism | 2 | 4 |
GO:0044003 | modulation by symbiont of host process | 3 | 4 |
GO:0044068 | modulation by symbiont of host cellular process | 4 | 4 |
GO:0044081 | modulation by symbiont of host nitric oxide-mediated signal transduction | 5 | 4 |
GO:0044403 | biological process involved in symbiotic interaction | 2 | 4 |
GO:0044419 | biological process involved in interspecies interaction between organisms | 1 | 4 |
GO:0044501 | modulation of signal transduction in another organism | 3 | 4 |
GO:0048583 | regulation of response to stimulus | 3 | 4 |
GO:0050789 | regulation of biological process | 2 | 4 |
GO:0050794 | regulation of cellular process | 3 | 4 |
GO:0051701 | biological process involved in interaction with host | 3 | 4 |
GO:0052027 | modulation by symbiont of host signal transduction pathway | 4 | 4 |
GO:0065007 | biological regulation | 1 | 4 |
GO:0075130 | modulation by symbiont of host protein kinase-mediated signal transduction | 5 | 4 |
GO:1902531 | regulation of intracellular signal transduction | 5 | 4 |
Term | Name | Level | Count |
---|---|---|---|
GO:0003824 | catalytic activity | 1 | 52 |
GO:0004175 | endopeptidase activity | 4 | 52 |
GO:0004222 | metalloendopeptidase activity | 5 | 52 |
GO:0005488 | binding | 1 | 52 |
GO:0008233 | peptidase activity | 3 | 52 |
GO:0008237 | metallopeptidase activity | 4 | 52 |
GO:0016787 | hydrolase activity | 2 | 52 |
GO:0043167 | ion binding | 2 | 52 |
GO:0043169 | cation binding | 3 | 52 |
GO:0046872 | metal ion binding | 4 | 52 |
GO:0140096 | catalytic activity, acting on a protein | 2 | 52 |
GO:0008047 | enzyme activator activity | 3 | 4 |
GO:0008160 | protein tyrosine phosphatase activator activity | 6 | 4 |
GO:0019208 | phosphatase regulator activity | 3 | 4 |
GO:0019211 | phosphatase activator activity | 4 | 4 |
GO:0019888 | protein phosphatase regulator activity | 4 | 4 |
GO:0030234 | enzyme regulator activity | 2 | 4 |
GO:0072542 | protein phosphatase activator activity | 5 | 4 |
GO:0098772 | molecular function regulator activity | 1 | 4 |
GO:0140677 | molecular function activator activity | 2 | 4 |
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_NRD_NRD_1 | 170 | 172 | PF00675 | 0.390 |
CLV_NRD_NRD_1 | 81 | 83 | PF00675 | 0.410 |
CLV_PCSK_KEX2_1 | 170 | 172 | PF00082 | 0.563 |
CLV_PCSK_KEX2_1 | 81 | 83 | PF00082 | 0.410 |
CLV_PCSK_SKI1_1 | 128 | 132 | PF00082 | 0.405 |
CLV_PCSK_SKI1_1 | 171 | 175 | PF00082 | 0.541 |
CLV_PCSK_SKI1_1 | 278 | 282 | PF00082 | 0.557 |
CLV_PCSK_SKI1_1 | 356 | 360 | PF00082 | 0.496 |
CLV_PCSK_SKI1_1 | 414 | 418 | PF00082 | 0.467 |
CLV_PCSK_SKI1_1 | 457 | 461 | PF00082 | 0.409 |
DEG_ODPH_VHL_1 | 29 | 41 | PF01847 | 0.556 |
DEG_SPOP_SBC_1 | 111 | 115 | PF00917 | 0.258 |
DEG_SPOP_SBC_1 | 563 | 567 | PF00917 | 0.195 |
DOC_CYCLIN_yCln2_LP_2 | 14 | 20 | PF00134 | 0.576 |
DOC_MAPK_gen_1 | 308 | 316 | PF00069 | 0.325 |
DOC_MAPK_MEF2A_6 | 9 | 18 | PF00069 | 0.580 |
DOC_PP2B_LxvP_1 | 14 | 17 | PF13499 | 0.581 |
DOC_PP2B_LxvP_1 | 362 | 365 | PF13499 | 0.379 |
DOC_PP2B_LxvP_1 | 90 | 93 | PF13499 | 0.258 |
DOC_PP4_FxxP_1 | 212 | 215 | PF00568 | 0.390 |
DOC_USP7_MATH_1 | 10 | 14 | PF00917 | 0.581 |
DOC_USP7_MATH_1 | 515 | 519 | PF00917 | 0.287 |
DOC_USP7_MATH_1 | 93 | 97 | PF00917 | 0.263 |
DOC_USP7_MATH_1 | 99 | 103 | PF00917 | 0.241 |
DOC_USP7_UBL2_3 | 410 | 414 | PF12436 | 0.207 |
DOC_WW_Pin1_4 | 112 | 117 | PF00397 | 0.276 |
DOC_WW_Pin1_4 | 316 | 321 | PF00397 | 0.253 |
DOC_WW_Pin1_4 | 511 | 516 | PF00397 | 0.233 |
DOC_WW_Pin1_4 | 552 | 557 | PF00397 | 0.403 |
LIG_14-3-3_CanoR_1 | 128 | 134 | PF00244 | 0.372 |
LIG_14-3-3_CanoR_1 | 193 | 201 | PF00244 | 0.189 |
LIG_14-3-3_CanoR_1 | 432 | 440 | PF00244 | 0.271 |
LIG_14-3-3_CanoR_1 | 536 | 542 | PF00244 | 0.368 |
LIG_14-3-3_CanoR_1 | 72 | 78 | PF00244 | 0.363 |
LIG_APCC_ABBA_1 | 183 | 188 | PF00400 | 0.390 |
LIG_APCC_ABBA_1 | 292 | 297 | PF00400 | 0.225 |
LIG_APCC_ABBA_1 | 377 | 382 | PF00400 | 0.378 |
LIG_APCC_ABBA_1 | 499 | 504 | PF00400 | 0.403 |
LIG_BRCT_BRCA1_1 | 402 | 406 | PF00533 | 0.273 |
LIG_BRCT_BRCA1_1 | 565 | 569 | PF00533 | 0.403 |
LIG_BRCT_BRCA1_2 | 565 | 571 | PF00533 | 0.198 |
LIG_FHA_1 | 124 | 130 | PF00498 | 0.311 |
LIG_FHA_1 | 174 | 180 | PF00498 | 0.256 |
LIG_FHA_1 | 196 | 202 | PF00498 | 0.300 |
LIG_FHA_1 | 209 | 215 | PF00498 | 0.295 |
LIG_FHA_1 | 218 | 224 | PF00498 | 0.281 |
LIG_FHA_1 | 279 | 285 | PF00498 | 0.324 |
LIG_FHA_1 | 374 | 380 | PF00498 | 0.394 |
LIG_FHA_1 | 538 | 544 | PF00498 | 0.385 |
LIG_FHA_1 | 565 | 571 | PF00498 | 0.277 |
LIG_FHA_2 | 129 | 135 | PF00498 | 0.222 |
LIG_FHA_2 | 200 | 206 | PF00498 | 0.233 |
LIG_FHA_2 | 291 | 297 | PF00498 | 0.247 |
LIG_FHA_2 | 331 | 337 | PF00498 | 0.209 |
LIG_FHA_2 | 389 | 395 | PF00498 | 0.238 |
LIG_FHA_2 | 493 | 499 | PF00498 | 0.209 |
LIG_GBD_Chelix_1 | 284 | 292 | PF00786 | 0.427 |
LIG_LIR_Apic_2 | 176 | 180 | PF02991 | 0.224 |
LIG_LIR_Apic_2 | 211 | 215 | PF02991 | 0.377 |
LIG_LIR_Apic_2 | 311 | 315 | PF02991 | 0.294 |
LIG_LIR_Gen_1 | 293 | 301 | PF02991 | 0.255 |
LIG_LIR_Gen_1 | 334 | 342 | PF02991 | 0.398 |
LIG_LIR_Gen_1 | 498 | 506 | PF02991 | 0.281 |
LIG_LIR_Nem_3 | 121 | 127 | PF02991 | 0.282 |
LIG_LIR_Nem_3 | 140 | 145 | PF02991 | 0.208 |
LIG_LIR_Nem_3 | 226 | 231 | PF02991 | 0.372 |
LIG_LIR_Nem_3 | 293 | 298 | PF02991 | 0.256 |
LIG_LIR_Nem_3 | 334 | 340 | PF02991 | 0.363 |
LIG_LIR_Nem_3 | 468 | 473 | PF02991 | 0.286 |
LIG_LIR_Nem_3 | 498 | 502 | PF02991 | 0.288 |
LIG_Pex14_1 | 419 | 423 | PF04695 | 0.392 |
LIG_PTB_Apo_2 | 222 | 229 | PF02174 | 0.383 |
LIG_SH2_CRK | 372 | 376 | PF00017 | 0.403 |
LIG_SH2_CRK | 473 | 477 | PF00017 | 0.273 |
LIG_SH2_CRK | 525 | 529 | PF00017 | 0.359 |
LIG_SH2_NCK_1 | 480 | 484 | PF00017 | 0.205 |
LIG_SH2_PTP2 | 94 | 97 | PF00017 | 0.283 |
LIG_SH2_STAP1 | 272 | 276 | PF00017 | 0.349 |
LIG_SH2_STAP1 | 480 | 484 | PF00017 | 0.210 |
LIG_SH2_STAP1 | 541 | 545 | PF00017 | 0.403 |
LIG_SH2_STAT3 | 145 | 148 | PF00017 | 0.251 |
LIG_SH2_STAT3 | 541 | 544 | PF00017 | 0.388 |
LIG_SH2_STAT5 | 142 | 145 | PF00017 | 0.234 |
LIG_SH2_STAT5 | 177 | 180 | PF00017 | 0.264 |
LIG_SH2_STAT5 | 231 | 234 | PF00017 | 0.376 |
LIG_SH2_STAT5 | 337 | 340 | PF00017 | 0.361 |
LIG_SH2_STAT5 | 372 | 375 | PF00017 | 0.329 |
LIG_SH2_STAT5 | 455 | 458 | PF00017 | 0.387 |
LIG_SH2_STAT5 | 473 | 476 | PF00017 | 0.215 |
LIG_SH2_STAT5 | 551 | 554 | PF00017 | 0.338 |
LIG_SH2_STAT5 | 94 | 97 | PF00017 | 0.361 |
LIG_SH3_3 | 233 | 239 | PF00018 | 0.253 |
LIG_SH3_3 | 258 | 264 | PF00018 | 0.202 |
LIG_SH3_3 | 518 | 524 | PF00018 | 0.236 |
LIG_SUMO_SIM_anti_2 | 296 | 303 | PF11976 | 0.226 |
LIG_TYR_ITIM | 335 | 340 | PF00017 | 0.387 |
LIG_TYR_ITIM | 471 | 476 | PF00017 | 0.202 |
LIG_TYR_ITIM | 92 | 97 | PF00017 | 0.326 |
MOD_CDK_SPK_2 | 511 | 516 | PF00069 | 0.254 |
MOD_CDK_SPxxK_3 | 552 | 559 | PF00069 | 0.405 |
MOD_CK1_1 | 234 | 240 | PF00069 | 0.473 |
MOD_CK1_1 | 318 | 324 | PF00069 | 0.228 |
MOD_CK1_1 | 348 | 354 | PF00069 | 0.421 |
MOD_CK1_1 | 490 | 496 | PF00069 | 0.359 |
MOD_CK1_1 | 500 | 506 | PF00069 | 0.283 |
MOD_CK2_1 | 128 | 134 | PF00069 | 0.199 |
MOD_CK2_1 | 199 | 205 | PF00069 | 0.250 |
MOD_CK2_1 | 290 | 296 | PF00069 | 0.240 |
MOD_CK2_1 | 330 | 336 | PF00069 | 0.236 |
MOD_CK2_1 | 388 | 394 | PF00069 | 0.493 |
MOD_CK2_1 | 492 | 498 | PF00069 | 0.267 |
MOD_GlcNHglycan | 101 | 104 | PF01048 | 0.253 |
MOD_GlcNHglycan | 120 | 123 | PF01048 | 0.286 |
MOD_GlcNHglycan | 269 | 272 | PF01048 | 0.240 |
MOD_GlcNHglycan | 345 | 348 | PF01048 | 0.414 |
MOD_GlcNHglycan | 366 | 369 | PF01048 | 0.277 |
MOD_GlcNHglycan | 548 | 551 | PF01048 | 0.424 |
MOD_GlcNHglycan | 87 | 90 | PF01048 | 0.440 |
MOD_GSK3_1 | 110 | 117 | PF00069 | 0.246 |
MOD_GSK3_1 | 195 | 202 | PF00069 | 0.326 |
MOD_GSK3_1 | 217 | 224 | PF00069 | 0.471 |
MOD_GSK3_1 | 272 | 279 | PF00069 | 0.362 |
MOD_GSK3_1 | 423 | 430 | PF00069 | 0.277 |
MOD_GSK3_1 | 487 | 494 | PF00069 | 0.277 |
MOD_GSK3_1 | 511 | 518 | PF00069 | 0.254 |
MOD_N-GLC_1 | 414 | 419 | PF02516 | 0.403 |
MOD_N-GLC_1 | 424 | 429 | PF02516 | 0.331 |
MOD_NEK2_1 | 110 | 115 | PF00069 | 0.243 |
MOD_NEK2_1 | 276 | 281 | PF00069 | 0.365 |
MOD_NEK2_1 | 290 | 295 | PF00069 | 0.396 |
MOD_NEK2_1 | 459 | 464 | PF00069 | 0.305 |
MOD_NEK2_1 | 562 | 567 | PF00069 | 0.225 |
MOD_NEK2_2 | 492 | 497 | PF00069 | 0.202 |
MOD_PIKK_1 | 414 | 420 | PF00454 | 0.382 |
MOD_PK_1 | 497 | 503 | PF00069 | 0.222 |
MOD_PKA_2 | 431 | 437 | PF00069 | 0.338 |
MOD_Plk_1 | 272 | 278 | PF00069 | 0.193 |
MOD_Plk_1 | 290 | 296 | PF00069 | 0.248 |
MOD_Plk_1 | 414 | 420 | PF00069 | 0.408 |
MOD_Plk_1 | 497 | 503 | PF00069 | 0.242 |
MOD_Plk_2-3 | 164 | 170 | PF00069 | 0.382 |
MOD_Plk_4 | 141 | 147 | PF00069 | 0.263 |
MOD_Plk_4 | 173 | 179 | PF00069 | 0.288 |
MOD_Plk_4 | 272 | 278 | PF00069 | 0.205 |
MOD_Plk_4 | 290 | 296 | PF00069 | 0.336 |
MOD_Plk_4 | 318 | 324 | PF00069 | 0.319 |
MOD_ProDKin_1 | 112 | 118 | PF00069 | 0.315 |
MOD_ProDKin_1 | 316 | 322 | PF00069 | 0.283 |
MOD_ProDKin_1 | 511 | 517 | PF00069 | 0.256 |
MOD_ProDKin_1 | 552 | 558 | PF00069 | 0.493 |
MOD_SUMO_for_1 | 358 | 361 | PF00179 | 0.344 |
MOD_SUMO_rev_2 | 297 | 307 | PF00179 | 0.205 |
TRG_DiLeu_BaEn_1 | 296 | 301 | PF01217 | 0.212 |
TRG_DiLeu_BaEn_3 | 168 | 174 | PF01217 | 0.263 |
TRG_ENDOCYTIC_2 | 337 | 340 | PF00928 | 0.434 |
TRG_ENDOCYTIC_2 | 372 | 375 | PF00928 | 0.493 |
TRG_ENDOCYTIC_2 | 473 | 476 | PF00928 | 0.379 |
TRG_ENDOCYTIC_2 | 525 | 528 | PF00928 | 0.467 |
TRG_ENDOCYTIC_2 | 94 | 97 | PF00928 | 0.326 |
TRG_ER_diArg_1 | 81 | 83 | PF00400 | 0.225 |
TRG_NES_CRM1_1 | 291 | 303 | PF08389 | 0.259 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N1IL11 | Leptomonas seymouri | 34% | 88% |
A0A0S4IP65 | Bodo saltans | 23% | 71% |
A0A0S4IUT6 | Bodo saltans | 30% | 70% |
A0A0S4IUU1 | Bodo saltans | 31% | 87% |
A0A0S4IYM3 | Bodo saltans | 31% | 79% |
A0A1D5NSK0 | Danio rerio | 24% | 92% |
A0A1X0NDG7 | Trypanosomatidae | 30% | 88% |
A0A1X0NDJ3 | Trypanosomatidae | 30% | 79% |
A0A1X0NDK7 | Trypanosomatidae | 31% | 80% |
A0A1X0NDU8 | Trypanosomatidae | 32% | 86% |
A0A1X0NE71 | Trypanosomatidae | 29% | 100% |
A0A1X0NER9 | Trypanosomatidae | 34% | 90% |
A0A1X0NET7 | Trypanosomatidae | 33% | 100% |
A0A1X0NEX7 | Trypanosomatidae | 33% | 88% |
A0A1X0NF32 | Trypanosomatidae | 31% | 100% |
A0A1X0NF41 | Trypanosomatidae | 32% | 94% |
A0A1X0NFJ0 | Trypanosomatidae | 28% | 100% |
A0A1X0NFK3 | Trypanosomatidae | 29% | 86% |
A0A1X0NFS0 | Trypanosomatidae | 29% | 66% |
A0A1X0NFU4 | Trypanosomatidae | 30% | 70% |
A0A1X0NG20 | Trypanosomatidae | 32% | 93% |
A0A1X0NGP3 | Trypanosomatidae | 31% | 67% |
A0A1X0NGY3 | Trypanosomatidae | 30% | 75% |
A0A1X0NGZ3 | Trypanosomatidae | 32% | 95% |
A0A1X0NHP6 | Trypanosomatidae | 32% | 100% |
A0A1X0NHQ6 | Trypanosomatidae | 33% | 100% |
A0A1X0NI74 | Trypanosomatidae | 30% | 77% |
A0A1X0NII4 | Trypanosomatidae | 29% | 68% |
A0A1X0NIZ3 | Trypanosomatidae | 31% | 100% |
A0A1X0NJS3 | Trypanosomatidae | 34% | 88% |
A0A1X0NJU4 | Trypanosomatidae | 31% | 67% |
A0A1X0NK66 | Trypanosomatidae | 35% | 87% |
A0A1X0NKJ8 | Trypanosomatidae | 28% | 77% |
A0A1X0NKW9 | Trypanosomatidae | 31% | 100% |
A0A1X0NME2 | Trypanosomatidae | 31% | 91% |
A0A1X0NMK3 | Trypanosomatidae | 28% | 100% |
A0A1X0NMK7 | Trypanosomatidae | 36% | 100% |
A0A1X0NMV0 | Trypanosomatidae | 30% | 78% |
A0A1X0NN43 | Trypanosomatidae | 27% | 80% |
A0A1X0NNK8 | Trypanosomatidae | 32% | 87% |
A0A1X0NPW0 | Trypanosomatidae | 31% | 89% |
A0A1X0NQM4 | Trypanosomatidae | 35% | 100% |
A0A1X0NQN3 | Trypanosomatidae | 35% | 100% |
A0A1X0NQU4 | Trypanosomatidae | 35% | 89% |
A0A1X0NQW6 | Trypanosomatidae | 34% | 100% |
A0A1X0NRF3 | Trypanosomatidae | 34% | 85% |
A0A1X0NRY8 | Trypanosomatidae | 36% | 100% |
A0A1X0NU16 | Trypanosomatidae | 36% | 96% |
A0A1X0NUR2 | Trypanosomatidae | 34% | 78% |
A0A1X0NV28 | Trypanosomatidae | 36% | 97% |
A0A1X0NVC3 | Trypanosomatidae | 28% | 84% |
A0A1X0NVE0 | Trypanosomatidae | 28% | 73% |
A0A1X0NW07 | Trypanosomatidae | 28% | 92% |
A0A1X0NX98 | Trypanosomatidae | 32% | 72% |
A0A1X0NXB6 | Trypanosomatidae | 31% | 81% |
A0A1X0NXH6 | Trypanosomatidae | 32% | 79% |
A0A1X0NXQ4 | Trypanosomatidae | 29% | 85% |
A0A1X0NXR7 | Trypanosomatidae | 32% | 76% |
A0A1X0NYE7 | Trypanosomatidae | 32% | 100% |
A0A1X0NYN2 | Trypanosomatidae | 34% | 100% |
A0A1X0NYN4 | Trypanosomatidae | 28% | 81% |
A0A1X0NYS5 | Trypanosomatidae | 34% | 96% |
A0A1X0NYZ2 | Trypanosomatidae | 38% | 100% |
A0A1X0NZ46 | Trypanosomatidae | 29% | 99% |
A0A1X0NZ63 | Trypanosomatidae | 31% | 90% |
A0A1X0NZN6 | Trypanosomatidae | 28% | 88% |
A0A1X0P055 | Trypanosomatidae | 36% | 97% |
A0A1X0P154 | Trypanosomatidae | 29% | 96% |
A0A1X0P331 | Trypanosomatidae | 33% | 100% |
A0A1X0P3K0 | Trypanosomatidae | 30% | 79% |
A0A1X0P3S2 | Trypanosomatidae | 29% | 100% |
A0A1X0P4L8 | Trypanosomatidae | 30% | 100% |
A0A1X0P4Y5 | Trypanosomatidae | 30% | 89% |
A0A1X0P5J0 | Trypanosomatidae | 33% | 84% |
A0A1X0P8B4 | Trypanosomatidae | 32% | 100% |
A0A1X0P9Z4 | Trypanosomatidae | 32% | 100% |
A0A1X0PB04 | Trypanosomatidae | 34% | 100% |
A0A3Q8I8N3 | Leishmania donovani | 59% | 96% |
A0A3Q8I8P8 | Leishmania donovani | 61% | 96% |
A0A3Q8I8S6 | Leishmania donovani | 62% | 90% |
A0A3Q8I8S9 | Leishmania donovani | 61% | 96% |
A0A3Q8IAZ8 | Leishmania donovani | 59% | 96% |
A0A3Q8IC35 | Leishmania donovani | 59% | 96% |
A0A3Q8IC44 | Leishmania donovani | 59% | 97% |
A0A3Q8IH61 | Leishmania donovani | 60% | 97% |
A0A3Q8IIN4 | Leishmania donovani | 34% | 90% |
A0A3R7JT49 | Trypanosoma rangeli | 35% | 68% |
A0A3R7JTB6 | Trypanosoma rangeli | 32% | 82% |
A0A3R7K7T9 | Trypanosoma rangeli | 35% | 96% |
A0A3R7K9S1 | Trypanosoma rangeli | 34% | 100% |
A0A3R7KMY2 | Trypanosoma rangeli | 34% | 86% |
A0A3R7LFC4 | Trypanosoma rangeli | 36% | 85% |
A0A3R7LFZ4 | Trypanosoma rangeli | 38% | 100% |
A0A3R7LX11 | Trypanosoma rangeli | 35% | 100% |
A0A3R7M1R8 | Trypanosoma rangeli | 35% | 100% |
A0A3R7M574 | Trypanosoma rangeli | 32% | 90% |
A0A3R7M7N6 | Trypanosoma rangeli | 33% | 83% |
A0A3R7MTS2 | Trypanosoma rangeli | 39% | 100% |
A0A3R7MW36 | Trypanosoma rangeli | 33% | 100% |
A0A3R7MXF4 | Trypanosoma rangeli | 37% | 94% |
A0A3R7N289 | Trypanosoma rangeli | 33% | 79% |
A0A3R7N7I3 | Trypanosoma rangeli | 40% | 100% |
A0A3R7NTI8 | Trypanosoma rangeli | 35% | 100% |
A0A3R7R2J4 | Trypanosoma rangeli | 33% | 89% |
A0A3R7R5R1 | Trypanosoma rangeli | 36% | 96% |
A0A3S5H6G0 | Leishmania donovani | 61% | 96% |
A0A3S5IQY2 | Trypanosoma rangeli | 37% | 100% |
A0A3S7WR43 | Leishmania donovani | 59% | 96% |
A0A3S7WR46 | Leishmania donovani | 61% | 96% |
A0A3S7WR60 | Leishmania donovani | 61% | 96% |
A0A3S7X192 | Leishmania donovani | 38% | 100% |
A0A422MRQ6 | Trypanosoma rangeli | 34% | 77% |
A0A422MU95 | Trypanosoma rangeli | 33% | 100% |
A0A422MVS3 | Trypanosoma rangeli | 35% | 100% |
A0A422MZ47 | Trypanosoma rangeli | 40% | 100% |
A0A422MZG4 | Trypanosoma rangeli | 35% | 98% |
A0A422N361 | Trypanosoma rangeli | 34% | 100% |
A0A422N7Q6 | Trypanosoma rangeli | 36% | 89% |
A0A422NDS2 | Trypanosoma rangeli | 36% | 99% |
A0A422NDT3 | Trypanosoma rangeli | 30% | 100% |
A4H626 | Leishmania braziliensis | 85% | 100% |
A4H627 | Leishmania braziliensis | 73% | 100% |
A4H629 | Leishmania braziliensis | 70% | 100% |
A4H630 | Leishmania braziliensis | 72% | 100% |
A4H631 | Leishmania braziliensis | 78% | 100% |
A4H632 | Leishmania braziliensis | 66% | 100% |
A4H633 | Leishmania braziliensis | 76% | 100% |
A4H634 | Leishmania braziliensis | 72% | 100% |
A4H635 | Leishmania braziliensis | 72% | 100% |
A4H636 | Leishmania braziliensis | 69% | 100% |
A4H637 | Leishmania braziliensis | 72% | 100% |
A4H638 | Leishmania braziliensis | 64% | 100% |
A4H639 | Leishmania braziliensis | 67% | 100% |
A4H640 | Leishmania braziliensis | 72% | 100% |
A4H6D3 | Leishmania braziliensis | 78% | 100% |
A4H6D5 | Leishmania braziliensis | 84% | 100% |
A4H6D7 | Leishmania braziliensis | 72% | 100% |
A4H6D8 | Leishmania braziliensis | 85% | 100% |
A4H6D9 | Leishmania braziliensis | 84% | 100% |
A4H6E0 | Leishmania braziliensis | 83% | 100% |
A4H6E1 | Leishmania braziliensis | 76% | 100% |
A4H6E2 | Leishmania braziliensis | 77% | 100% |
A4H6E4 | Leishmania braziliensis | 81% | 100% |
A4H6E5 | Leishmania braziliensis | 69% | 100% |
A4HJI2 | Leishmania braziliensis | 37% | 89% |
A4HUF6 | Leishmania infantum | 59% | 96% |
A4HUF8 | Leishmania infantum | 61% | 96% |
A4HUF9 | Leishmania infantum | 62% | 90% |
A4HUG0 | Leishmania infantum | 61% | 75% |
A4I6X5 | Leishmania infantum | 36% | 90% |
C9ZUT5 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 35% | 99% |
D0A1R8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 33% | 97% |
D0A7S8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 31% | 85% |
D0A855 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 35% | 93% |
E9AHH5 | Leishmania infantum | 38% | 100% |
E9AN53 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 64% | 88% |
E9AN54 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 59% | 95% |
E9AN55 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 61% | 89% |
E9AN56 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 63% | 89% |
E9AN57 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 59% | 95% |
E9AZL8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 39% | 100% |
E9B1Z9 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 35% | 90% |
O62446 | Caenorhabditis elegans | 26% | 87% |
P08148 | Leishmania major | 61% | 95% |
P15706 | Leishmania chagasi | 61% | 96% |
P23223 | Leishmania donovani | 59% | 97% |
P43150 | Leishmania mexicana | 62% | 89% |
Q00689 | Leishmania guyanensis | 72% | 92% |
Q06031 | Crithidia fasciculata | 51% | 88% |
Q27673 | Leishmania amazonensis | 59% | 96% |
Q29AK2 | Drosophila pseudoobscura pseudoobscura | 25% | 84% |
Q4Q662 | Leishmania major | 36% | 100% |
Q4Q8L3 | Leishmania major | 39% | 100% |
Q4QHG9 | Leishmania major | 61% | 100% |
Q4QHH0 | Leishmania major | 62% | 100% |
Q4QHH1 | Leishmania major | 61% | 100% |
Q4QHH2 | Leishmania major | 61% | 100% |
Q61YG1 | Caenorhabditis briggsae | 25% | 87% |
Q6LA77 | Leishmania infantum | 61% | 96% |
Q8MNZ1 | Leishmania tropica | 62% | 87% |
Q9VH19 | Drosophila melanogaster | 23% | 84% |
V5A359 | Trypanosoma cruzi | 38% | 100% |
V5A488 | Trypanosoma cruzi | 32% | 71% |
V5AII7 | Trypanosoma cruzi | 38% | 100% |
V5APQ4 | Trypanosoma cruzi | 32% | 72% |
V5AX72 | Trypanosoma cruzi | 36% | 78% |
V5B5M0 | Trypanosoma cruzi | 35% | 78% |
V5BAN1 | Trypanosoma cruzi | 34% | 73% |
V5BD39 | Trypanosoma cruzi | 40% | 100% |
V5BLT3 | Trypanosoma cruzi | 31% | 91% |
V5D358 | Trypanosoma cruzi | 34% | 68% |