LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H6D6_LEIBR
TriTrypDb:
LbrM.10.1600 , LBRM2903_100019000 *
Length:
58

Annotations

LeishMANIAdb annotations

A very simple single-pass membrane protein restricted to Kinetoplastids. Might be mitochondrial.. A transit peptide cannot be excluded in the sequence.. Localization: Mitochondrial (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6D6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6D6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 43 45 PF00675 0.708
CLV_PCSK_KEX2_1 42 44 PF00082 0.712
DEG_APCC_DBOX_1 9 17 PF00400 0.718
LIG_14-3-3_CanoR_1 42 51 PF00244 0.714
LIG_BIR_II_1 1 5 PF00653 0.806
LIG_LIR_Nem_3 28 34 PF02991 0.735
LIG_Pex14_2 11 15 PF04695 0.714
LIG_RPA_C_Fungi 39 51 PF08784 0.709
LIG_SH2_NCK_1 53 57 PF00017 0.746
LIG_SH2_STAT5 17 20 PF00017 0.687
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS