LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H6C7_LEIBR
TriTrypDb:
LbrM.10.1500 , LBRM2903_080014300 *
Length:
317

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H6C7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H6C7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 246 248 PF00675 0.691
CLV_NRD_NRD_1 33 35 PF00675 0.646
CLV_PCSK_KEX2_1 246 248 PF00082 0.691
CLV_PCSK_KEX2_1 256 258 PF00082 0.544
CLV_PCSK_KEX2_1 33 35 PF00082 0.646
CLV_PCSK_KEX2_1 71 73 PF00082 0.451
CLV_PCSK_PC1ET2_1 256 258 PF00082 0.558
CLV_PCSK_PC1ET2_1 71 73 PF00082 0.451
CLV_PCSK_SKI1_1 33 37 PF00082 0.503
DEG_SCF_TRCP1_1 175 180 PF00400 0.570
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PEG2 Leptomonas seymouri 37% 100%
A0A3S5H670 Leishmania donovani 58% 100%
A4HTM6 Leishmania infantum 58% 100%
E9AMG0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 59% 100%
Q4QI83 Leishmania major 58% 93%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS