Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

WD domain, G-beta repeat, putative

Species:

Leishmania braziliensis

UniProt:

A4H666_LEIBR

TriTrypDb:

LbrM.10.0880 , LBRM2903_100017200

Length:

419

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	11
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11
GO:0005737	cytoplasm	2	1
GO:0005815	microtubule organizing center	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0036064	ciliary basal body	3	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1

Expansion

Sequence features

A4H666

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H666

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	370	372	PF00082	0.365
CLV_PCSK_PC1ET2_1	370	372	PF00082	0.365
CLV_PCSK_SKI1_1	109	113	PF00082	0.371
CLV_PCSK_SKI1_1	152	156	PF00082	0.271
CLV_PCSK_SKI1_1	362	366	PF00082	0.378
CLV_PCSK_SKI1_1	4	8	PF00082	0.372
DEG_APCC_DBOX_1	370	378	PF00400	0.526
DEG_Nend_UBRbox_1	1	4	PF02207	0.402
DOC_ANK_TNKS_1	8	15	PF00023	0.342
DOC_CKS1_1	38	43	PF01111	0.537
DOC_MAPK_DCC_7	9	17	PF00069	0.339
DOC_MAPK_gen_1	59	68	PF00069	0.348
DOC_MAPK_gen_1	89	98	PF00069	0.478
DOC_MAPK_HePTP_8	56	68	PF00069	0.386
DOC_MAPK_MEF2A_6	59	68	PF00069	0.344
DOC_MAPK_MEF2A_6	9	17	PF00069	0.339
DOC_MAPK_NFAT4_5	61	69	PF00069	0.283
DOC_PP1_RVXF_1	351	357	PF00149	0.471
DOC_PP4_FxxP_1	145	148	PF00568	0.471
DOC_USP7_MATH_1	125	129	PF00917	0.443
DOC_USP7_MATH_1	154	158	PF00917	0.471
DOC_USP7_MATH_1	322	326	PF00917	0.509
DOC_USP7_UBL2_3	105	109	PF12436	0.565
DOC_WW_Pin1_4	34	39	PF00397	0.498
LIG_14-3-3_CanoR_1	303	312	PF00244	0.478
LIG_14-3-3_CanoR_1	331	341	PF00244	0.571
LIG_14-3-3_CterR_2	415	419	PF00244	0.565
LIG_BRCT_BRCA1_1	268	272	PF00533	0.471
LIG_BRCT_BRCA1_1	394	398	PF00533	0.471
LIG_BRCT_BRCA1_1	81	85	PF00533	0.321
LIG_Clathr_ClatBox_1	130	134	PF01394	0.565
LIG_FHA_1	116	122	PF00498	0.471
LIG_FHA_1	159	165	PF00498	0.471
LIG_FHA_1	175	181	PF00498	0.471
LIG_FHA_1	201	207	PF00498	0.471
LIG_FHA_1	220	226	PF00498	0.493
LIG_FHA_1	243	249	PF00498	0.528
LIG_FHA_1	251	257	PF00498	0.456
LIG_FHA_1	279	285	PF00498	0.475
LIG_FHA_1	28	34	PF00498	0.416
LIG_FHA_1	304	310	PF00498	0.471
LIG_FHA_1	327	333	PF00498	0.479
LIG_FHA_1	359	365	PF00498	0.471
LIG_FHA_1	37	43	PF00498	0.425
LIG_FHA_1	377	383	PF00498	0.428
LIG_FHA_1	388	394	PF00498	0.520
LIG_FHA_1	411	417	PF00498	0.471
LIG_FHA_1	82	88	PF00498	0.416
LIG_FHA_2	124	130	PF00498	0.409
LIG_FHA_2	215	221	PF00498	0.478
LIG_FHA_2	230	236	PF00498	0.503
LIG_FHA_2	257	263	PF00498	0.535
LIG_FHA_2	38	44	PF00498	0.414
LIG_IBAR_NPY_1	147	149	PF08397	0.490
LIG_LIR_Gen_1	62	72	PF02991	0.352
LIG_LIR_Gen_1	82	93	PF02991	0.387
LIG_LIR_LC3C_4	276	280	PF02991	0.565
LIG_LIR_Nem_3	232	236	PF02991	0.565
LIG_LIR_Nem_3	62	68	PF02991	0.353
LIG_LIR_Nem_3	82	88	PF02991	0.394
LIG_Pex14_2	394	398	PF04695	0.471
LIG_PTB_Apo_2	54	61	PF02174	0.521
LIG_PTB_Apo_2	97	104	PF02174	0.471
LIG_PTB_Phospho_1	54	60	PF10480	0.524
LIG_SH2_NCK_1	333	337	PF00017	0.535
LIG_SH2_STAP1	19	23	PF00017	0.460
LIG_SH2_STAP1	274	278	PF00017	0.526
LIG_SH2_STAT3	60	63	PF00017	0.426
LIG_SH2_STAT5	141	144	PF00017	0.579
LIG_SH2_STAT5	67	70	PF00017	0.404
LIG_SH3_3	35	41	PF00018	0.560
LIG_SUMO_SIM_par_1	128	134	PF11976	0.308
LIG_SUMO_SIM_par_1	32	37	PF11976	0.442
MOD_CK1_1	325	331	PF00069	0.536
MOD_CK1_1	376	382	PF00069	0.352
MOD_CK2_1	123	129	PF00069	0.389
MOD_CK2_1	256	262	PF00069	0.582
MOD_CK2_1	349	355	PF00069	0.565
MOD_CK2_1	37	43	PF00069	0.546
MOD_GlcNHglycan	168	171	PF01048	0.497
MOD_GlcNHglycan	20	24	PF01048	0.462
MOD_GlcNHglycan	294	297	PF01048	0.408
MOD_GlcNHglycan	316	319	PF01048	0.293
MOD_GlcNHglycan	322	325	PF01048	0.259
MOD_GlcNHglycan	366	369	PF01048	0.294
MOD_GSK3_1	111	118	PF00069	0.470
MOD_GSK3_1	121	128	PF00069	0.564
MOD_GSK3_1	154	161	PF00069	0.476
MOD_GSK3_1	174	181	PF00069	0.560
MOD_GSK3_1	190	197	PF00069	0.379
MOD_GSK3_1	238	245	PF00069	0.479
MOD_GSK3_1	252	259	PF00069	0.416
MOD_GSK3_1	280	287	PF00069	0.565
MOD_GSK3_1	32	39	PF00069	0.560
MOD_GSK3_1	322	329	PF00069	0.495
MOD_GSK3_1	358	365	PF00069	0.471
MOD_GSK3_1	406	413	PF00069	0.488
MOD_GSK3_1	79	86	PF00069	0.558
MOD_N-GLC_2	412	414	PF02516	0.271
MOD_NEK2_1	158	163	PF00069	0.496
MOD_NEK2_1	194	199	PF00069	0.483
MOD_NEK2_1	200	205	PF00069	0.459
MOD_NEK2_1	236	241	PF00069	0.475
MOD_NEK2_1	242	247	PF00069	0.477
MOD_NEK2_1	278	283	PF00069	0.475
MOD_NEK2_1	314	319	PF00069	0.471
MOD_NEK2_1	320	325	PF00069	0.471
MOD_NEK2_1	394	399	PF00069	0.616
MOD_NEK2_1	87	92	PF00069	0.475
MOD_NEK2_2	115	120	PF00069	0.471
MOD_NEK2_2	298	303	PF00069	0.471
MOD_PIKK_1	79	85	PF00454	0.423
MOD_Plk_1	265	271	PF00069	0.565
MOD_Plk_2-3	129	135	PF00069	0.471
MOD_Plk_4	190	196	PF00069	0.528
MOD_Plk_4	214	220	PF00069	0.485
MOD_Plk_4	252	258	PF00069	0.431
MOD_Plk_4	382	388	PF00069	0.565
MOD_Plk_4	401	407	PF00069	0.471
MOD_ProDKin_1	34	40	PF00069	0.492
TRG_DiLeu_BaLyEn_6	51	56	PF01217	0.394
TRG_ENDOCYTIC_2	233	236	PF00928	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3X3	Leptomonas seymouri	25%	94%
A0A0N0P4D4	Leptomonas seymouri	22%	100%
A0A0N0P7N2	Leptomonas seymouri	24%	81%
A0A0N1I6C2	Leptomonas seymouri	91%	100%
A0A0N1IHN2	Leptomonas seymouri	27%	80%
A0A0N1IMQ0	Leptomonas seymouri	23%	77%
A0A0N1PB16	Leptomonas seymouri	28%	100%
A0A0N1PB29	Leptomonas seymouri	20%	67%
A0A0N1PC28	Leptomonas seymouri	25%	96%
A0A0S4ITM8	Bodo saltans	22%	86%
A0A0S4IUZ3	Bodo saltans	24%	75%
A0A0S4IWG1	Bodo saltans	26%	86%
A0A0S4IWU9	Bodo saltans	25%	100%
A0A0S4J5T5	Bodo saltans	29%	78%
A0A0S4J6C2	Bodo saltans	23%	94%
A0A0S4JC99	Bodo saltans	22%	90%
A0A0S4JE21	Bodo saltans	41%	100%
A0A0S4JEJ1	Bodo saltans	24%	100%
A0A0S4JJ02	Bodo saltans	22%	67%
A0A0S4JL38	Bodo saltans	39%	78%
A0A0S4JPK4	Bodo saltans	23%	70%
A0A0S4JPX5	Bodo saltans	24%	94%
A0A0S4JQ88	Bodo saltans	24%	100%
A0A0S4JQ93	Bodo saltans	34%	76%
A0A0S4KJ87	Bodo saltans	28%	70%
A0A0S4KK54	Bodo saltans	26%	100%
A0A0S4KLR3	Bodo saltans	27%	86%
A0A1X0NQ54	Trypanosomatidae	26%	100%
A0A1X0NQ96	Trypanosomatidae	74%	100%
A0A1X0NQI7	Trypanosomatidae	27%	100%
A0A1X0NS60	Trypanosomatidae	25%	79%
A0A1X0NVZ7	Trypanosomatidae	28%	80%
A0A1X0NZP7	Trypanosomatidae	23%	87%
A0A1X0P0F0	Trypanosomatidae	23%	90%
A0A1X0P1V8	Trypanosomatidae	23%	90%
A0A1X0P3N7	Trypanosomatidae	24%	100%
A0A1X0P458	Trypanosomatidae	24%	100%
A0A1X0P551	Trypanosomatidae	22%	94%
A0A1X0P716	Trypanosomatidae	30%	71%
A0A2R8QFQ6	Danio rerio	30%	75%
A0A2R8RWN9	Danio rerio	30%	78%
A0A3Q8IBR2	Leishmania donovani	25%	99%
A0A3Q8IGC4	Leishmania donovani	28%	80%
A0A3Q8IGD2	Leishmania donovani	25%	96%
A0A3Q8IHK6	Leishmania donovani	21%	100%
A0A3Q8IHW0	Leishmania donovani	24%	76%
A0A3R7KDE0	Trypanosoma rangeli	26%	100%
A0A3R7KUH0	Trypanosoma rangeli	73%	99%
A0A3R7M2T7	Trypanosoma rangeli	25%	100%
A0A3R7MCP0	Trypanosoma rangeli	25%	91%
A0A3R7MF36	Trypanosoma rangeli	25%	97%
A0A3R7N6M9	Trypanosoma rangeli	30%	80%
A0A3R7NG85	Trypanosoma rangeli	23%	71%
A0A3R7NW31	Trypanosoma rangeli	22%	88%
A0A3S5ISA7	Trypanosoma rangeli	23%	95%
A0A3S7WR72	Leishmania donovani	98%	100%
A0A3S7WUV4	Leishmania donovani	31%	68%
A0A3S7WZV3	Leishmania donovani	22%	72%
A0A3S7X9Q7	Leishmania donovani	25%	94%
A0A3S7XBP3	Leishmania donovani	24%	82%
A0A422N1P8	Trypanosoma rangeli	25%	94%
A0A422NAT5	Trypanosoma rangeli	24%	79%
A0A422NIT0	Trypanosoma rangeli	25%	84%
A0A422NKQ7	Trypanosoma rangeli	23%	100%
A0AUS0	Danio rerio	28%	86%
A0CH87	Paramecium tetraurelia	28%	100%
A0DB19	Paramecium tetraurelia	28%	100%
A1CF18	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	96%
A1CUD6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	90%
A1DP19	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	28%	95%
A1L271	Danio rerio	27%	100%
A2CEH0	Danio rerio	28%	86%
A2QP30	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	95%
A4H9F5	Leishmania braziliensis	30%	67%
A4HDT7	Leishmania braziliensis	27%	80%
A4HE87	Leishmania braziliensis	22%	80%
A4HFQ0	Leishmania braziliensis	24%	100%
A4HGF6	Leishmania braziliensis	23%	67%
A4HGX7	Leishmania braziliensis	28%	100%
A4HI91	Leishmania braziliensis	23%	76%
A4HL42	Leishmania braziliensis	23%	95%
A4HN59	Leishmania braziliensis	24%	100%
A4HPZ9	Leishmania braziliensis	23%	82%
A4HUJ0	Leishmania infantum	98%	100%
A4HXS2	Leishmania infantum	31%	68%
A4HZL2	Leishmania infantum	25%	99%
A4I135	Leishmania infantum	28%	80%
A4I269	Leishmania infantum	22%	72%
A4I2S5	Leishmania infantum	21%	100%
A4I5H1	Leishmania infantum	24%	76%
A4I8M2	Leishmania infantum	25%	96%
A4IBS6	Leishmania infantum	24%	94%
A4IDR0	Leishmania infantum	24%	82%
A4R3M4	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	27%	91%
A7EKM8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	28%	91%
A7RWD2	Nematostella vectensis	24%	100%
A7S338	Nematostella vectensis	27%	100%
A8NEG8	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	28%	97%
A8X8C6	Caenorhabditis briggsae	35%	100%
A8XZJ9	Caenorhabditis briggsae	29%	100%
A9V790	Monosiga brevicollis	27%	100%
B0LSW3	Felis catus	30%	100%
B0XAF3	Culex quinquefasciatus	24%	100%
B0XM00	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	28%	90%
B2AEZ5	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	30%	90%
B2B766	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	29%	90%
B2VWG7	Pyrenophora tritici-repentis (strain Pt-1C-BFP)	29%	91%
B3MC74	Drosophila ananassae	24%	100%
B3MEY6	Drosophila ananassae	29%	100%
B3MJV8	Drosophila ananassae	26%	100%
B3NPW0	Drosophila erecta	28%	100%
B3S4I5	Trichoplax adhaerens	30%	100%
B4GAJ1	Drosophila persimilis	29%	100%
B4GT01	Drosophila persimilis	26%	100%
B4HSL3	Drosophila sechellia	28%	100%
B4JW81	Drosophila grimshawi	24%	100%
B4JWA1	Drosophila grimshawi	29%	100%
B4KT48	Drosophila mojavensis	29%	100%
B4KTK4	Drosophila mojavensis	24%	100%
B4LJT7	Drosophila virilis	24%	100%
B4LQ21	Drosophila virilis	29%	100%
B4LS78	Drosophila virilis	26%	100%
B4MY65	Drosophila willistoni	29%	100%
B4P6P9	Drosophila yakuba	28%	100%
B4QHG6	Drosophila simulans	28%	100%
B5X212	Salmo salar	26%	100%
B5X3C4	Salmo salar	29%	100%
B5X3Z6	Salmo salar	28%	100%
B6GZD3	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	27%	90%
B6HP56	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	31%	91%
B6QC06	Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)	28%	93%
B6QC56	Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)	27%	91%
B7FNU7	Phaeodactylum tricornutum (strain CCAP 1055/1)	27%	95%
B7PS00	Ixodes scapularis	30%	100%
B8AP31	Oryza sativa subsp. indica	29%	100%
B8M0Q1	Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)	28%	91%
B8N9H4	Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)	28%	92%
B8P4B0	Postia placenta (strain ATCC 44394 / Madison 698-R)	31%	96%
B8PD53	Postia placenta (strain ATCC 44394 / Madison 698-R)	31%	98%
C0NRC6	Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC 2432)	27%	92%
C0S902	Paracoccidioides brasiliensis (strain Pb03)	28%	88%
C1GB49	Paracoccidioides brasiliensis (strain Pb18)	28%	88%
C3XVT5	Branchiostoma floridae	30%	100%
C4JPW9	Uncinocarpus reesii (strain UAMH 1704)	29%	91%
C4JZS6	Uncinocarpus reesii (strain UAMH 1704)	26%	94%
C4Q0P6	Schistosoma mansoni	32%	100%
C4YFX2	Candida albicans (strain WO-1)	28%	82%
C5FWH1	Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)	29%	91%
C5GVJ9	Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586)	28%	89%
C5JD40	Blastomyces gilchristii (strain SLH14081)	28%	89%
C5PFX0	Coccidioides posadasii (strain C735)	28%	89%
C6HTE8	Ajellomyces capsulatus (strain H143)	27%	92%
C7Z6H2	Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4)	29%	94%
C9ZK82	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	81%
C9ZPU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	82%
C9ZQV5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	92%
C9ZRS8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	84%
C9ZVL4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
C9ZW72	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	68%
C9ZYU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	94%
D0A054	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	71%
D0A0R2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	81%
D0A4F2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	94%
D0A8F9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A8Z9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D1ZEB4	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	29%	91%
D1ZEM6	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	27%	86%
D3BUN1	Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500)	27%	100%
D3TLL6	Glossina morsitans morsitans	29%	100%
D3ZW91	Rattus norvegicus	27%	88%
D4AZ50	Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)	28%	91%
D4DG66	Trichophyton verrucosum (strain HKI 0517)	28%	91%
D5GBI7	Tuber melanosporum (strain Mel28)	26%	93%
E8NHN2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9ADA3	Leishmania major	21%	90%
E9AFL2	Leishmania major	24%	100%
E9AN88	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9ARI4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	67%
E9ATR6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	82%
E9AUX2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	99%
E9AX72	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	80%
E9AXR7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	80%
E9AYB9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	72%
E9AZ28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	100%
E9AZS9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	67%
E9B0R9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	76%
E9B3I3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	96%
E9B6R6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	94%
F6ZT52	Xenopus tropicalis	28%	89%
G0SC29	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	27%	81%
G4MQX3	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	25%	100%
O13615	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	89%
O13982	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
O14435	Cryphonectria parasitica	27%	100%
O14775	Homo sapiens	26%	100%
O15736	Dictyostelium discoideum	28%	68%
O18640	Drosophila melanogaster	25%	100%
O22212	Arabidopsis thaliana	28%	76%
O22785	Arabidopsis thaliana	26%	80%
O24076	Medicago sativa	26%	100%
O24456	Arabidopsis thaliana	27%	100%
O35353	Rattus norvegicus	26%	100%
O43017	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
O43172	Homo sapiens	28%	80%
O43660	Homo sapiens	30%	82%
O45040	Homarus americanus	25%	100%
O60907	Homo sapiens	26%	73%
O74855	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	83%
O76071	Homo sapiens	26%	100%
O76734	Dictyostelium discoideum	30%	72%
O80990	Arabidopsis thaliana	27%	100%
O94620	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
P0CS42	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	30%	97%
P0CS43	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	30%	97%
P0CS48	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	27%	89%
P0CS49	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	27%	89%
P0CY34	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	82%
P11017	Bos taurus	25%	100%
P16520	Homo sapiens	26%	100%
P17343	Caenorhabditis elegans	26%	100%
P20053	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	90%
P23232	Loligo forbesii	24%	100%
P25382	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	81%
P25387	Chlamydomonas reinhardtii	27%	100%
P26308	Drosophila melanogaster	27%	100%
P29387	Mus musculus	26%	100%
P29829	Drosophila melanogaster	26%	100%
P36408	Dictyostelium discoideum	25%	100%
P38011	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P42841	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	90%
P43033	Bos taurus	30%	100%
P43034	Homo sapiens	30%	100%
P46800	Dictyostelium discoideum	28%	100%
P49027	Oryza sativa subsp. japonica	28%	100%
P49177	Arabidopsis thaliana	24%	100%
P49178	Zea mays	27%	100%
P52287	Rattus norvegicus	27%	100%
P54311	Rattus norvegicus	25%	100%
P54313	Rattus norvegicus	25%	100%
P61964	Homo sapiens	35%	100%
P61965	Mus musculus	35%	100%
P62871	Bos taurus	25%	100%
P62872	Canis lupus familiaris	25%	100%
P62873	Homo sapiens	25%	100%
P62874	Mus musculus	25%	100%
P62879	Homo sapiens	25%	100%
P62880	Mus musculus	25%	100%
P62881	Mus musculus	27%	100%
P62882	Rattus norvegicus	27%	100%
P62883	Leishmania chagasi	28%	100%
P62884	Leishmania infantum	28%	100%
P63004	Rattus norvegicus	30%	100%
P63005	Mus musculus	30%	100%
P69103	Trypanosoma brucei brucei	26%	100%
P69104	Trypanosoma brucei rhodesiense	26%	100%
P74598	Synechocystis sp. (strain PCC 6803 / Kazusa)	23%	100%
P78706	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	69%
P79147	Canis lupus familiaris	27%	100%
P79959	Xenopus laevis	26%	100%
P87053	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	69%
P93107	Chlamydomonas reinhardtii	30%	69%
P93339	Nicotiana plumbaginifolia	27%	100%
P93397	Nicotiana tabacum	28%	100%
P93398	Nicotiana tabacum	27%	100%
P93563	Solanum tuberosum	27%	100%
Q00664	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	27%	94%
Q08706	Lymnaea stagnalis	24%	100%
Q08E38	Bos taurus	25%	83%
Q09715	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	68%
Q09855	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	83%
Q0D0X6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	25%	94%
Q0P593	Bos taurus	59%	100%
Q0U1B1	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	29%	91%
Q10281	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
Q12417	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	93%
Q13685	Homo sapiens	25%	97%
Q17963	Caenorhabditis elegans	31%	100%
Q17GR9	Aedes aegypti	25%	100%
Q17N69	Aedes aegypti	28%	100%
Q1LV15	Danio rerio	59%	100%
Q20636	Caenorhabditis elegans	27%	100%
Q21215	Caenorhabditis elegans	25%	100%
Q229Z6	Tetrahymena thermophila (strain SB210)	24%	66%
Q23256	Caenorhabditis elegans	33%	84%
Q25306	Leishmania major	28%	100%
Q26544	Schistosoma mansoni	23%	100%
Q28I85	Xenopus tropicalis	30%	95%
Q291L9	Drosophila pseudoobscura pseudoobscura	29%	100%
Q29KQ0	Drosophila pseudoobscura pseudoobscura	26%	100%
Q2GT28	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	30%	92%
Q2HBX6	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	29%	92%
Q2HJH6	Bos taurus	29%	100%
Q2KID6	Bos taurus	30%	82%
Q2KIG2	Bos taurus	35%	100%
Q2TAY7	Homo sapiens	22%	82%
Q2TBP4	Bos taurus	29%	100%
Q2TBS9	Bos taurus	22%	82%
Q2UGU1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	28%	92%
Q32LN7	Bos taurus	28%	100%
Q32PJ6	Bos taurus	28%	100%
Q39190	Arabidopsis thaliana	28%	87%
Q39336	Brassica napus	27%	100%
Q39836	Glycine max	26%	100%
Q3MHE2	Bos taurus	27%	80%
Q3SZK1	Bos taurus	25%	97%
Q3UKJ7	Mus musculus	22%	82%
Q3ULA2	Mus musculus	30%	69%
Q3Y8L7	Chlamydomonas reinhardtii	65%	94%
Q40507	Nicotiana tabacum	27%	100%
Q40687	Oryza sativa subsp. japonica	29%	100%
Q42384	Arabidopsis thaliana	28%	86%
Q498M4	Rattus norvegicus	35%	100%
Q4ICM0	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	30%	91%
Q4P9P9	Ustilago maydis (strain 521 / FGSC 9021)	29%	92%
Q4Q0T1	Leishmania major	25%	100%
Q4Q7Y7	Leishmania major	28%	100%
Q4Q9Q4	Leishmania major	23%	80%
Q4QAA4	Leishmania major	28%	80%
Q4QCL0	Leishmania major	23%	100%
Q4QDZ5	Leishmania major	29%	67%
Q4QHD6	Leishmania major	97%	100%
Q4R8E7	Macaca fascicularis	59%	100%
Q4R8H1	Macaca fascicularis	26%	74%
Q4RJN5	Tetraodon nigroviridis	29%	100%
Q4V7A0	Rattus norvegicus	29%	100%
Q4V7Z1	Xenopus laevis	28%	90%
Q4V8C4	Rattus norvegicus	34%	100%
Q4WLM7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	28%	90%
Q4WT34	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	27%	92%
Q54KL5	Dictyostelium discoideum	32%	100%
Q55AR8	Dictyostelium discoideum	27%	100%
Q58D20	Bos taurus	26%	86%
Q5A7Q3	Candida albicans (strain SC5314 / ATCC MYA-2876)	23%	100%
Q5BE22	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	27%	93%
Q5BK30	Rattus norvegicus	59%	100%
Q5BLX8	Rattus norvegicus	26%	100%
Q5FVN8	Rattus norvegicus	28%	88%
Q5FWQ6	Xenopus laevis	60%	100%
Q5GIS3	Pinctada fucata	25%	100%
Q5I0B9	Xenopus tropicalis	26%	67%
Q5IS43	Pan troglodytes	30%	100%
Q5JTN6	Homo sapiens	31%	100%
Q5M786	Xenopus tropicalis	35%	100%
Q5M7T1	Rattus norvegicus	27%	100%
Q5NVD0	Pongo abelii	27%	80%
Q5R5W8	Pongo abelii	25%	100%
Q5R650	Pongo abelii	29%	85%
Q5RCG7	Pongo abelii	25%	97%
Q5RD06	Pongo abelii	25%	93%
Q5RDY7	Pongo abelii	26%	100%
Q5RE95	Pongo abelii	33%	100%
Q5REG7	Pongo abelii	30%	100%
Q5RF51	Pongo abelii	29%	100%
Q5RFF8	Pongo abelii	25%	86%
Q5SRY7	Mus musculus	30%	77%
Q5XGI5	Xenopus tropicalis	25%	100%
Q5ZJH5	Gallus gallus	28%	100%
Q5ZMA2	Gallus gallus	24%	83%
Q5ZMC3	Gallus gallus	28%	88%
Q5ZME8	Gallus gallus	22%	82%
Q61011	Mus musculus	27%	100%
Q61FW2	Caenorhabditis briggsae	34%	71%
Q61ZF6	Caenorhabditis briggsae	26%	100%
Q676U5	Homo sapiens	24%	69%
Q6BU94	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	100%
Q6C709	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	95%
Q6CB13	Yarrowia lipolytica (strain CLIB 122 / E 150)	26%	74%
Q6CKE8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	24%	97%
Q6DH44	Danio rerio	25%	100%
Q6FJ73	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	28%	100%
Q6FJS0	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	92%
Q6FJZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	98%
Q6GMD2	Xenopus laevis	29%	100%
Q6GPC6	Xenopus laevis	27%	80%
Q6L4F8	Oryza sativa subsp. japonica	27%	100%
Q6NRT3	Xenopus laevis	22%	82%
Q6NZH4	Xenopus tropicalis	30%	100%
Q6P2Y2	Xenopus tropicalis	60%	100%
Q6P4J8	Xenopus tropicalis	22%	82%
Q6P5M2	Danio rerio	31%	100%
Q6PBD6	Xenopus tropicalis	30%	100%
Q6PBY0	Danio rerio	26%	100%
Q6PE01	Mus musculus	30%	100%
Q6PH57	Danio rerio	26%	100%
Q6PNB6	Oryctolagus cuniculus	26%	100%
Q6TMK6	Cricetulus griseus	25%	100%
Q6ZMY6	Homo sapiens	28%	89%
Q75BY3	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	99%
Q76B40	Cricetulus griseus	22%	82%
Q76LS6	Leishmania donovani	28%	100%
Q7KNS3	Drosophila melanogaster	28%	100%
Q7PS24	Anopheles gambiae	23%	100%
Q7QJ33	Anopheles gambiae	28%	98%
Q7RY30	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	92%
Q7S7L4	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	86%
Q7SZM9	Xenopus laevis	27%	81%
Q7T0P4	Xenopus laevis	30%	95%
Q7T2F6	Danio rerio	27%	99%
Q7T394	Danio rerio	29%	100%
Q7YR70	Canis lupus familiaris	24%	96%
Q7ZVA0	Danio rerio	23%	82%
Q7ZVF0	Danio rerio	30%	100%
Q7ZXK9	Xenopus laevis	26%	88%
Q803D2	Danio rerio	29%	100%
Q80ZD0	Tamias striatus	26%	100%
Q86TI4	Homo sapiens	31%	100%
Q86VZ2	Homo sapiens	33%	100%
Q8BHD1	Mus musculus	26%	88%
Q8BHJ5	Mus musculus	27%	82%
Q8CBE3	Mus musculus	28%	84%
Q8HXX0	Macaca fascicularis	30%	100%
Q8I0F4	Dictyostelium discoideum	28%	100%
Q8JZX3	Mus musculus	30%	100%
Q8N0X2	Homo sapiens	27%	66%
Q8N136	Homo sapiens	59%	100%
Q8N9V3	Homo sapiens	26%	88%
Q8NBT0	Homo sapiens	30%	100%
Q8TC44	Homo sapiens	26%	88%
Q8VEJ4	Mus musculus	26%	86%
Q8W117	Arabidopsis thaliana	23%	82%
Q90ZL4	Xenopus laevis	31%	100%
Q91854	Xenopus laevis	30%	81%
Q91WQ5	Mus musculus	24%	71%
Q922B6	Mus musculus	27%	71%
Q922V4	Mus musculus	30%	82%
Q93134	Biomphalaria glabrata	26%	100%
Q93794	Caenorhabditis elegans	34%	71%
Q93847	Caenorhabditis elegans	30%	100%
Q94BR4	Arabidopsis thaliana	26%	80%
Q96DI7	Homo sapiens	29%	100%
Q99KN2	Mus musculus	26%	100%
Q99KP6	Mus musculus	25%	83%
Q99M63	Rattus norvegicus	22%	82%
Q9AV81	Oryza sativa subsp. japonica	29%	80%
Q9AYE4	Oryza sativa subsp. japonica	26%	100%
Q9BQ87	Homo sapiens	25%	80%
Q9BZK7	Homo sapiens	27%	82%
Q9D0I6	Mus musculus	27%	88%
Q9D7H2	Mus musculus	34%	100%
Q9DAJ4	Mus musculus	25%	100%
Q9DAW6	Mus musculus	27%	80%
Q9ERF3	Mus musculus	29%	100%
Q9FKT5	Arabidopsis thaliana	26%	100%
Q9FLX9	Arabidopsis thaliana	27%	89%
Q9FN19	Arabidopsis thaliana	30%	68%
Q9GL51	Sus scrofa	30%	100%
Q9GZS3	Homo sapiens	28%	100%
Q9HAV0	Homo sapiens	26%	100%
Q9JMJ4	Rattus norvegicus	25%	83%
Q9LV27	Arabidopsis thaliana	23%	100%
Q9M2Z2	Arabidopsis thaliana	32%	100%
Q9NDC9	Caenorhabditis elegans	27%	100%
Q9NVX2	Homo sapiens	26%	86%
Q9PTR5	Gallus gallus	30%	100%
Q9QXE7	Mus musculus	25%	80%
Q9SY00	Arabidopsis thaliana	34%	100%
Q9SZQ5	Arabidopsis thaliana	24%	100%
Q9UKB1	Homo sapiens	29%	77%
Q9UMS4	Homo sapiens	25%	83%
Q9UTC7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	91%
Q9UUG8	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	70%
Q9V3J8	Drosophila melanogaster	35%	100%
Q9VPR4	Drosophila melanogaster	27%	86%
Q9VU65	Drosophila melanogaster	24%	100%
Q9WUC8	Rattus norvegicus	30%	82%
Q9Y297	Homo sapiens	30%	69%
V5B4Z8	Trypanosoma cruzi	24%	95%
V5B6G4	Trypanosoma cruzi	29%	100%
V5BDQ2	Trypanosoma cruzi	27%	100%
V5BE86	Trypanosoma cruzi	22%	100%
V5BEB2	Trypanosoma cruzi	28%	78%
V5BEB9	Trypanosoma cruzi	23%	84%
V5BJG9	Trypanosoma cruzi	22%	94%
V5BP59	Trypanosoma cruzi	74%	100%
V5BQL6	Trypanosoma cruzi	24%	100%
V5BRZ9	Trypanosoma cruzi	22%	78%
V5BW76	Trypanosoma cruzi	23%	76%
V5BYY0	Trypanosoma cruzi	25%	94%
V5DB29	Trypanosoma cruzi	22%	77%
V5DUL4	Trypanosoma cruzi	24%	94%