LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania braziliensis
UniProt:
A4H622_LEIBR
TriTrypDb:
LbrM.10.0430 , LBRM2903_100009900 *
Length:
693

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H622
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H622

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 115 119 PF00656 0.643
CLV_C14_Caspase3-7 168 172 PF00656 0.646
CLV_C14_Caspase3-7 281 285 PF00656 0.625
CLV_NRD_NRD_1 324 326 PF00675 0.708
CLV_NRD_NRD_1 344 346 PF00675 0.658
CLV_NRD_NRD_1 539 541 PF00675 0.710
CLV_NRD_NRD_1 666 668 PF00675 0.635
CLV_PCSK_KEX2_1 324 326 PF00082 0.711
CLV_PCSK_KEX2_1 344 346 PF00082 0.655
CLV_PCSK_KEX2_1 539 541 PF00082 0.748
CLV_PCSK_KEX2_1 546 548 PF00082 0.726
CLV_PCSK_KEX2_1 668 670 PF00082 0.617
CLV_PCSK_PC1ET2_1 546 548 PF00082 0.768
CLV_PCSK_PC1ET2_1 668 670 PF00082 0.617
CLV_PCSK_PC7_1 320 326 PF00082 0.706
CLV_PCSK_SKI1_1 368 372 PF00082 0.633
CLV_PCSK_SKI1_1 540 544 PF00082 0.686
DEG_SPOP_SBC_1 461 465 PF00917 0.559
DEG_SPOP_SBC_1 503 507 PF00917 0.621
DOC_CDC14_PxL_1 480 488 PF14671 0.493
DOC_CKS1_1 183 188 PF01111 0.684
DOC_CKS1_1 607 612 PF01111 0.673
DOC_CYCLIN_RxL_1 88 98 PF00134 0.725
DOC_CYCLIN_yCln2_LP_2 35 41 PF00134 0.642
DOC_MAPK_gen_1 344 350 PF00069 0.637
DOC_MAPK_gen_1 373 383 PF00069 0.778
DOC_MAPK_MEF2A_6 3 11 PF00069 0.598
DOC_MAPK_MEF2A_6 376 385 PF00069 0.668
DOC_MAPK_RevD_3 127 141 PF00069 0.621
DOC_MAPK_RevD_3 7 22 PF00069 0.616
DOC_PP2B_LxvP_1 207 210 PF13499 0.590
DOC_PP2B_LxvP_1 35 38 PF13499 0.637
DOC_PP2B_LxvP_1 83 86 PF13499 0.605
DOC_PP4_FxxP_1 219 222 PF00568 0.604
DOC_USP7_MATH_1 152 156 PF00917 0.830
DOC_USP7_MATH_1 174 178 PF00917 0.685
DOC_USP7_MATH_1 225 229 PF00917 0.638
DOC_USP7_MATH_1 254 258 PF00917 0.720
DOC_USP7_MATH_1 264 268 PF00917 0.739
DOC_USP7_MATH_1 390 394 PF00917 0.743
DOC_USP7_MATH_1 397 401 PF00917 0.775
DOC_USP7_MATH_1 49 53 PF00917 0.625
DOC_USP7_MATH_1 503 507 PF00917 0.650
DOC_USP7_MATH_1 508 512 PF00917 0.799
DOC_USP7_MATH_1 548 552 PF00917 0.706
DOC_USP7_MATH_1 648 652 PF00917 0.628
DOC_USP7_MATH_1 97 101 PF00917 0.591
DOC_WW_Pin1_4 154 159 PF00397 0.718
DOC_WW_Pin1_4 182 187 PF00397 0.687
DOC_WW_Pin1_4 218 223 PF00397 0.807
DOC_WW_Pin1_4 241 246 PF00397 0.610
DOC_WW_Pin1_4 259 264 PF00397 0.533
DOC_WW_Pin1_4 285 290 PF00397 0.816
DOC_WW_Pin1_4 3 8 PF00397 0.798
DOC_WW_Pin1_4 319 324 PF00397 0.851
DOC_WW_Pin1_4 33 38 PF00397 0.844
DOC_WW_Pin1_4 337 342 PF00397 0.694
DOC_WW_Pin1_4 357 362 PF00397 0.501
DOC_WW_Pin1_4 47 52 PF00397 0.609
DOC_WW_Pin1_4 504 509 PF00397 0.752
DOC_WW_Pin1_4 520 525 PF00397 0.547
DOC_WW_Pin1_4 562 567 PF00397 0.701
DOC_WW_Pin1_4 606 611 PF00397 0.675
DOC_WW_Pin1_4 635 640 PF00397 0.609
DOC_WW_Pin1_4 78 83 PF00397 0.810
DOC_WW_Pin1_4 95 100 PF00397 0.504
LIG_14-3-3_CanoR_1 146 151 PF00244 0.770
LIG_14-3-3_CanoR_1 313 319 PF00244 0.626
LIG_14-3-3_CanoR_1 356 363 PF00244 0.649
LIG_14-3-3_CanoR_1 411 416 PF00244 0.578
LIG_14-3-3_CanoR_1 421 425 PF00244 0.454
LIG_14-3-3_CanoR_1 427 433 PF00244 0.390
LIG_14-3-3_CanoR_1 527 535 PF00244 0.713
LIG_14-3-3_CanoR_1 539 548 PF00244 0.672
LIG_14-3-3_CanoR_1 597 606 PF00244 0.638
LIG_14-3-3_CanoR_1 634 638 PF00244 0.663
LIG_14-3-3_CanoR_1 674 684 PF00244 0.670
LIG_Actin_WH2_2 405 423 PF00022 0.614
LIG_Actin_WH2_2 430 446 PF00022 0.624
LIG_BIR_II_1 1 5 PF00653 0.651
LIG_BRCT_BRCA1_1 488 492 PF00533 0.558
LIG_FHA_1 13 19 PF00498 0.567
LIG_FHA_1 202 208 PF00498 0.659
LIG_FHA_1 337 343 PF00498 0.614
LIG_FHA_1 389 395 PF00498 0.613
LIG_FHA_1 4 10 PF00498 0.596
LIG_FHA_1 407 413 PF00498 0.510
LIG_FHA_1 417 423 PF00498 0.475
LIG_FHA_1 453 459 PF00498 0.636
LIG_FHA_1 573 579 PF00498 0.687
LIG_FHA_1 62 68 PF00498 0.582
LIG_FHA_1 636 642 PF00498 0.684
LIG_FHA_2 113 119 PF00498 0.767
LIG_FHA_2 162 168 PF00498 0.691
LIG_FHA_2 373 379 PF00498 0.633
LIG_FHA_2 559 565 PF00498 0.686
LIG_Integrin_RGD_1 25 27 PF01839 0.646
LIG_LIR_Apic_2 217 222 PF02991 0.606
LIG_LIR_Apic_2 678 683 PF02991 0.670
LIG_LIR_Gen_1 489 498 PF02991 0.569
LIG_LIR_Nem_3 489 495 PF02991 0.548
LIG_MYND_1 206 210 PF01753 0.586
LIG_MYND_1 37 41 PF01753 0.635
LIG_MYND_1 484 488 PF01753 0.437
LIG_SH2_STAP1 138 142 PF00017 0.608
LIG_SH2_STAT5 440 443 PF00017 0.489
LIG_SH2_STAT5 452 455 PF00017 0.477
LIG_SH2_STAT5 680 683 PF00017 0.613
LIG_SH3_1 325 331 PF00018 0.625
LIG_SH3_2 289 294 PF14604 0.602
LIG_SH3_3 106 112 PF00018 0.630
LIG_SH3_3 126 132 PF00018 0.518
LIG_SH3_3 155 161 PF00018 0.838
LIG_SH3_3 180 186 PF00018 0.713
LIG_SH3_3 286 292 PF00018 0.702
LIG_SH3_3 31 37 PF00018 0.847
LIG_SH3_3 325 331 PF00018 0.749
LIG_SH3_3 340 346 PF00018 0.658
LIG_SH3_3 552 558 PF00018 0.763
LIG_SH3_3 560 566 PF00018 0.613
LIG_SH3_3 615 621 PF00018 0.734
LIG_SUMO_SIM_anti_2 52 58 PF11976 0.617
LIG_SUMO_SIM_par_1 201 212 PF11976 0.596
LIG_SUMO_SIM_par_1 52 58 PF11976 0.676
LIG_TRAF2_1 302 305 PF00917 0.626
LIG_TRAF2_1 375 378 PF00917 0.749
LIG_TRAF2_1 42 45 PF00917 0.641
LIG_WW_2 328 331 PF00397 0.618
MOD_CDC14_SPxK_1 322 325 PF00782 0.700
MOD_CDK_SPK_2 319 324 PF00069 0.851
MOD_CDK_SPxK_1 241 247 PF00069 0.613
MOD_CDK_SPxK_1 319 325 PF00069 0.707
MOD_CDK_SPxxK_3 259 266 PF00069 0.643
MOD_CDK_SPxxK_3 337 344 PF00069 0.818
MOD_CDK_SPxxK_3 520 527 PF00069 0.724
MOD_CDK_SPxxK_3 95 102 PF00069 0.590
MOD_CK1_1 191 197 PF00069 0.641
MOD_CK1_1 211 217 PF00069 0.631
MOD_CK1_1 262 268 PF00069 0.673
MOD_CK1_1 311 317 PF00069 0.707
MOD_CK1_1 357 363 PF00069 0.647
MOD_CK1_1 395 401 PF00069 0.617
MOD_CK1_1 416 422 PF00069 0.624
MOD_CK1_1 50 56 PF00069 0.815
MOD_CK1_1 504 510 PF00069 0.656
MOD_CK1_1 511 517 PF00069 0.707
MOD_CK1_1 526 532 PF00069 0.604
MOD_CK1_1 58 64 PF00069 0.652
MOD_CK1_1 583 589 PF00069 0.665
MOD_CK1_1 599 605 PF00069 0.574
MOD_CK1_1 676 682 PF00069 0.678
MOD_CK2_1 246 252 PF00069 0.778
MOD_CK2_1 299 305 PF00069 0.627
MOD_CK2_1 372 378 PF00069 0.746
MOD_CK2_1 401 407 PF00069 0.527
MOD_CK2_1 558 564 PF00069 0.685
MOD_DYRK1A_RPxSP_1 3 7 PF00069 0.799
MOD_GlcNHglycan 154 157 PF01048 0.761
MOD_GlcNHglycan 176 179 PF01048 0.737
MOD_GlcNHglycan 194 197 PF01048 0.617
MOD_GlcNHglycan 211 214 PF01048 0.590
MOD_GlcNHglycan 235 238 PF01048 0.669
MOD_GlcNHglycan 248 251 PF01048 0.594
MOD_GlcNHglycan 266 269 PF01048 0.557
MOD_GlcNHglycan 27 30 PF01048 0.681
MOD_GlcNHglycan 312 316 PF01048 0.671
MOD_GlcNHglycan 363 366 PF01048 0.814
MOD_GlcNHglycan 415 418 PF01048 0.652
MOD_GlcNHglycan 428 431 PF01048 0.384
MOD_GlcNHglycan 513 516 PF01048 0.790
MOD_GlcNHglycan 529 532 PF01048 0.573
MOD_GlcNHglycan 575 578 PF01048 0.657
MOD_GlcNHglycan 581 585 PF01048 0.607
MOD_GlcNHglycan 648 651 PF01048 0.627
MOD_GlcNHglycan 659 662 PF01048 0.590
MOD_GlcNHglycan 675 678 PF01048 0.624
MOD_GSK3_1 188 195 PF00069 0.635
MOD_GSK3_1 214 221 PF00069 0.738
MOD_GSK3_1 254 261 PF00069 0.747
MOD_GSK3_1 319 326 PF00069 0.740
MOD_GSK3_1 357 364 PF00069 0.804
MOD_GSK3_1 372 379 PF00069 0.581
MOD_GSK3_1 388 395 PF00069 0.519
MOD_GSK3_1 397 404 PF00069 0.547
MOD_GSK3_1 416 423 PF00069 0.511
MOD_GSK3_1 469 476 PF00069 0.690
MOD_GSK3_1 504 511 PF00069 0.696
MOD_GSK3_1 522 529 PF00069 0.620
MOD_GSK3_1 549 556 PF00069 0.848
MOD_GSK3_1 558 565 PF00069 0.648
MOD_GSK3_1 57 64 PF00069 0.681
MOD_GSK3_1 573 580 PF00069 0.668
MOD_GSK3_1 592 599 PF00069 0.583
MOD_GSK3_1 657 664 PF00069 0.675
MOD_GSK3_1 683 690 PF00069 0.603
MOD_N-GLC_1 133 138 PF02516 0.623
MOD_N-GLC_1 259 264 PF02516 0.638
MOD_NEK2_1 151 156 PF00069 0.823
MOD_NEK2_1 199 204 PF00069 0.649
MOD_NEK2_1 450 455 PF00069 0.615
MOD_NEK2_1 675 680 PF00069 0.645
MOD_NEK2_1 685 690 PF00069 0.610
MOD_NEK2_2 133 138 PF00069 0.614
MOD_PIKK_1 12 18 PF00454 0.678
MOD_PIKK_1 201 207 PF00454 0.601
MOD_PIKK_1 553 559 PF00454 0.636
MOD_PIKK_1 648 654 PF00454 0.630
MOD_PIKK_1 67 73 PF00454 0.672
MOD_PIKK_1 685 691 PF00454 0.611
MOD_PIKK_1 85 91 PF00454 0.629
MOD_PK_1 344 350 PF00069 0.841
MOD_PKA_1 344 350 PF00069 0.841
MOD_PKA_2 246 252 PF00069 0.632
MOD_PKA_2 277 283 PF00069 0.719
MOD_PKA_2 293 299 PF00069 0.503
MOD_PKA_2 344 350 PF00069 0.841
MOD_PKA_2 355 361 PF00069 0.646
MOD_PKA_2 372 378 PF00069 0.559
MOD_PKA_2 395 401 PF00069 0.821
MOD_PKA_2 420 426 PF00069 0.600
MOD_PKA_2 511 517 PF00069 0.791
MOD_PKA_2 526 532 PF00069 0.585
MOD_PKA_2 535 541 PF00069 0.506
MOD_PKA_2 596 602 PF00069 0.662
MOD_PKA_2 633 639 PF00069 0.661
MOD_PKA_2 673 679 PF00069 0.672
MOD_PKB_1 144 152 PF00069 0.575
MOD_Plk_1 12 18 PF00069 0.643
MOD_Plk_1 133 139 PF00069 0.609
MOD_Plk_1 225 231 PF00069 0.618
MOD_Plk_1 311 317 PF00069 0.610
MOD_Plk_1 377 383 PF00069 0.634
MOD_Plk_1 406 412 PF00069 0.416
MOD_Plk_4 121 127 PF00069 0.848
MOD_Plk_4 133 139 PF00069 0.631
MOD_Plk_4 146 152 PF00069 0.697
MOD_Plk_4 293 299 PF00069 0.619
MOD_Plk_4 50 56 PF00069 0.825
MOD_Plk_4 530 536 PF00069 0.699
MOD_Plk_4 558 564 PF00069 0.627
MOD_ProDKin_1 154 160 PF00069 0.720
MOD_ProDKin_1 182 188 PF00069 0.684
MOD_ProDKin_1 218 224 PF00069 0.809
MOD_ProDKin_1 241 247 PF00069 0.613
MOD_ProDKin_1 259 265 PF00069 0.535
MOD_ProDKin_1 285 291 PF00069 0.816
MOD_ProDKin_1 3 9 PF00069 0.800
MOD_ProDKin_1 319 325 PF00069 0.853
MOD_ProDKin_1 33 39 PF00069 0.847
MOD_ProDKin_1 337 343 PF00069 0.816
MOD_ProDKin_1 357 363 PF00069 0.502
MOD_ProDKin_1 47 53 PF00069 0.608
MOD_ProDKin_1 504 510 PF00069 0.751
MOD_ProDKin_1 520 526 PF00069 0.547
MOD_ProDKin_1 562 568 PF00069 0.702
MOD_ProDKin_1 606 612 PF00069 0.670
MOD_ProDKin_1 635 641 PF00069 0.612
MOD_ProDKin_1 78 84 PF00069 0.809
MOD_ProDKin_1 95 101 PF00069 0.504
MOD_SUMO_for_1 587 590 PF00179 0.761
MOD_SUMO_rev_2 14 23 PF00179 0.630
MOD_SUMO_rev_2 236 245 PF00179 0.638
TRG_DiLeu_BaLyEn_6 203 208 PF01217 0.743
TRG_DiLeu_BaLyEn_6 88 93 PF01217 0.724
TRG_ENDOCYTIC_2 440 443 PF00928 0.514
TRG_ER_diArg_1 323 325 PF00400 0.701
TRG_ER_diArg_1 343 345 PF00400 0.646
TRG_ER_diArg_1 539 541 PF00400 0.687
TRG_ER_FFAT_1 277 288 PF00635 0.622
TRG_Pf-PMV_PEXEL_1 627 632 PF00026 0.625
TRG_Pf-PMV_PEXEL_1 91 96 PF00026 0.724

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8I8R8 Leishmania donovani 55% 100%
A4HUF0 Leishmania infantum 57% 100%
E9AN49 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS