LeishMANIAdb
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Sulfurtransferase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Sulfurtransferase
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H5X4_LEIBR
TriTrypDb:
LbrM.09.1530 , LBRM2903_090021900 *
Length:
119

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5X4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5X4

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 8
GO:0004792 thiosulfate sulfurtransferase activity 5 8
GO:0016740 transferase activity 2 8
GO:0016782 transferase activity, transferring sulphur-containing groups 3 8
GO:0016783 sulfurtransferase activity 4 8

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_3 1 3 PF02207 0.493
DOC_USP7_MATH_1 70 74 PF00917 0.452
DOC_USP7_UBL2_3 62 66 PF12436 0.355
LIG_14-3-3_CanoR_1 3 7 PF00244 0.406
LIG_BRCT_BRCA1_1 94 98 PF00533 0.347
LIG_FHA_1 76 82 PF00498 0.517
LIG_FHA_2 55 61 PF00498 0.494
LIG_FHA_2 97 103 PF00498 0.460
LIG_LIR_Apic_2 63 68 PF02991 0.450
LIG_LIR_Gen_1 5 14 PF02991 0.446
LIG_LIR_Gen_1 95 105 PF02991 0.460
LIG_LIR_Nem_3 95 101 PF02991 0.473
LIG_PDZ_Class_1 114 119 PF00595 0.358
LIG_SH2_CRK 65 69 PF00017 0.494
LIG_SH2_STAT5 79 82 PF00017 0.444
LIG_SH3_3 40 46 PF00018 0.447
LIG_SUMO_SIM_par_1 24 30 PF11976 0.509
MOD_CK1_1 96 102 PF00069 0.439
MOD_CK2_1 104 110 PF00069 0.427
MOD_CK2_1 27 33 PF00069 0.495
MOD_CK2_1 54 60 PF00069 0.514
MOD_CMANNOS 108 111 PF00535 0.244
MOD_GlcNHglycan 115 119 PF01048 0.442
MOD_GlcNHglycan 17 20 PF01048 0.297
MOD_GlcNHglycan 29 32 PF01048 0.242
MOD_GlcNHglycan 51 54 PF01048 0.263
MOD_GlcNHglycan 87 90 PF01048 0.325
MOD_GlcNHglycan 95 98 PF01048 0.314
MOD_GSK3_1 92 99 PF00069 0.489
MOD_NEK2_1 92 97 PF00069 0.492
MOD_PKA_1 15 21 PF00069 0.456
MOD_PKA_2 2 8 PF00069 0.432
MOD_PKA_2 93 99 PF00069 0.355
MOD_SUMO_for_1 68 71 PF00179 0.494
TRG_ENDOCYTIC_2 6 9 PF00928 0.395
TRG_ER_diLys_1 114 119 PF00400 0.358

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P899 Leptomonas seymouri 31% 91%
A0A0N0P8M5 Leptomonas seymouri 65% 100%
A0A0N1PG29 Leptomonas seymouri 35% 88%
A0A1X0NHS7 Trypanosomatidae 50% 100%
A0A1X0NIC3 Trypanosomatidae 47% 100%
A0A1X0NJI4 Trypanosomatidae 31% 87%
A0A1X0NJQ7 Trypanosomatidae 33% 82%
A0A3R7LB88 Trypanosoma rangeli 49% 96%
A0A3R7MT99 Trypanosoma rangeli 35% 87%
A0A3R7P0U7 Trypanosoma rangeli 33% 82%
A0A3S7WQW6 Leishmania donovani 35% 79%
A0A3S7WQX1 Leishmania donovani 85% 100%
A4H5X3 Leishmania braziliensis 35% 100%
A4HU68 Leishmania infantum 35% 79%
A4HU69 Leishmania infantum 85% 100%
D0A9P9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 87%
D0A9Q0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 83%
E9AMZ8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 35% 79%
E9AMZ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
P22978 Drosophila melanogaster 43% 100%
P54510 Bacillus subtilis (strain 168) 33% 94%
Q08742 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 80%
Q10215 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 41% 84%
Q12305 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 32% 86%
Q4QHM8 Leishmania major 83% 100%
Q4QHM9 Leishmania major 35% 100%
Q8NFU3 Homo sapiens 45% 100%
Q9D0B5 Mus musculus 39% 76%
V5BI16 Trypanosoma cruzi 32% 73%
V5BMN5 Trypanosoma cruzi 37% 84%
V5BMN9 Trypanosoma cruzi 43% 96%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS