Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H5V9_LEIBR

TriTrypDb:

LbrM.09.1370 , LBRM2903_090020400

Length:

348

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5V9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5V9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	319	323	PF00656	0.559
CLV_NRD_NRD_1	110	112	PF00675	0.573
CLV_NRD_NRD_1	282	284	PF00675	0.701
CLV_PCSK_KEX2_1	110	112	PF00082	0.573
CLV_PCSK_KEX2_1	282	284	PF00082	0.704
CLV_PCSK_SKI1_1	116	120	PF00082	0.576
DEG_MDM2_SWIB_1	53	61	PF02201	0.534
DEG_Nend_UBRbox_1	1	4	PF02207	0.603
DEG_SPOP_SBC_1	314	318	PF00917	0.580
DOC_MAPK_MEF2A_6	121	128	PF00069	0.479
DOC_PP2B_LxvP_1	174	177	PF13499	0.518
DOC_USP7_MATH_1	13	17	PF00917	0.721
DOC_USP7_MATH_1	178	182	PF00917	0.732
DOC_USP7_MATH_1	22	26	PF00917	0.649
DOC_WW_Pin1_4	190	195	PF00397	0.728
DOC_WW_Pin1_4	205	210	PF00397	0.509
DOC_WW_Pin1_4	213	218	PF00397	0.684
DOC_WW_Pin1_4	25	30	PF00397	0.682
DOC_WW_Pin1_4	83	88	PF00397	0.579
LIG_14-3-3_CanoR_1	121	127	PF00244	0.479
LIG_14-3-3_CanoR_1	273	279	PF00244	0.553
LIG_Actin_WH2_2	51	68	PF00022	0.379
LIG_BRCT_BRCA1_1	85	89	PF00533	0.543
LIG_deltaCOP1_diTrp_1	243	247	PF00928	0.535
LIG_EVH1_2	5	9	PF00568	0.531
LIG_FHA_1	123	129	PF00498	0.481
LIG_FHA_1	253	259	PF00498	0.803
LIG_FHA_1	292	298	PF00498	0.711
LIG_FHA_2	191	197	PF00498	0.767
LIG_FHA_2	42	48	PF00498	0.528
LIG_LIR_Gen_1	135	145	PF02991	0.759
LIG_LIR_Gen_1	196	206	PF02991	0.628
LIG_LIR_Nem_3	135	140	PF02991	0.695
LIG_LIR_Nem_3	196	201	PF02991	0.641
LIG_LIR_Nem_3	243	247	PF02991	0.572
LIG_LIR_Nem_3	267	272	PF02991	0.801
LIG_MYND_1	270	274	PF01753	0.802
LIG_MYND_1	33	37	PF01753	0.508
LIG_PDZ_Class_3	343	348	PF00595	0.760
LIG_Pex14_2	53	57	PF04695	0.517
LIG_PTB_Apo_2	47	54	PF02174	0.558
LIG_SH2_STAT5	67	70	PF00017	0.513
LIG_SH3_3	101	107	PF00018	0.643
LIG_SH3_3	16	22	PF00018	0.791
LIG_SH3_3	268	274	PF00018	0.609
LIG_SH3_CIN85_PxpxPR_1	29	34	PF14604	0.539
LIG_SUMO_SIM_anti_2	16	27	PF11976	0.794
LIG_SUMO_SIM_anti_2	294	301	PF11976	0.812
LIG_SUMO_SIM_anti_2	337	346	PF11976	0.675
LIG_SUMO_SIM_par_1	122	127	PF11976	0.481
LIG_SUMO_SIM_par_1	16	28	PF11976	0.794
LIG_SUMO_SIM_par_1	294	301	PF11976	0.719
LIG_SUMO_SIM_par_1	337	346	PF11976	0.667
MOD_CDK_SPxxK_3	190	197	PF00069	0.579
MOD_CDK_SPxxK_3	205	212	PF00069	0.679
MOD_CDK_SPxxK_3	27	34	PF00069	0.671
MOD_CK1_1	133	139	PF00069	0.494
MOD_CK1_1	180	186	PF00069	0.732
MOD_CK1_1	216	222	PF00069	0.705
MOD_CK1_1	246	252	PF00069	0.547
MOD_CK1_1	25	31	PF00069	0.675
MOD_CK1_1	265	271	PF00069	0.477
MOD_CK1_1	316	322	PF00069	0.607
MOD_CK2_1	133	139	PF00069	0.746
MOD_CK2_1	190	196	PF00069	0.728
MOD_CK2_1	20	26	PF00069	0.640
MOD_CK2_1	205	211	PF00069	0.472
MOD_CK2_1	88	94	PF00069	0.758
MOD_GlcNHglycan	128	131	PF01048	0.587
MOD_GlcNHglycan	180	183	PF01048	0.648
MOD_GlcNHglycan	218	221	PF01048	0.693
MOD_GlcNHglycan	248	251	PF01048	0.636
MOD_GlcNHglycan	264	267	PF01048	0.802
MOD_GlcNHglycan	278	281	PF01048	0.678
MOD_GlcNHglycan	309	312	PF01048	0.732
MOD_GlcNHglycan	73	77	PF01048	0.537
MOD_GSK3_1	122	129	PF00069	0.590
MOD_GSK3_1	168	175	PF00069	0.663
MOD_GSK3_1	178	185	PF00069	0.681
MOD_GSK3_1	21	28	PF00069	0.667
MOD_GSK3_1	215	222	PF00069	0.664
MOD_GSK3_1	248	255	PF00069	0.659
MOD_GSK3_1	258	265	PF00069	0.713
MOD_GSK3_1	274	281	PF00069	0.506
MOD_GSK3_1	313	320	PF00069	0.655
MOD_GSK3_1	88	95	PF00069	0.681
MOD_NEK2_1	172	177	PF00069	0.525
MOD_NEK2_1	252	257	PF00069	0.622
MOD_NEK2_1	258	263	PF00069	0.658
MOD_NEK2_1	278	283	PF00069	0.552
MOD_NEK2_1	72	77	PF00069	0.532
MOD_NEK2_2	41	46	PF00069	0.584
MOD_PIKK_1	144	150	PF00454	0.648
MOD_PIKK_1	232	238	PF00454	0.479
MOD_PKA_2	307	313	PF00069	0.833
MOD_Plk_1	72	78	PF00069	0.643
MOD_Plk_4	182	188	PF00069	0.565
MOD_Plk_4	293	299	PF00069	0.586
MOD_ProDKin_1	190	196	PF00069	0.728
MOD_ProDKin_1	205	211	PF00069	0.514
MOD_ProDKin_1	213	219	PF00069	0.680
MOD_ProDKin_1	25	31	PF00069	0.684
MOD_ProDKin_1	83	89	PF00069	0.577
MOD_SUMO_for_1	150	153	PF00179	0.530

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4T4	Leptomonas seymouri	33%	95%
A0A3S7WQV7	Leishmania donovani	66%	99%
E9ACQ8	Leishmania major	69%	100%
E9AG96	Leishmania infantum	66%	99%
E9AMY3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	99%