A very small protein, that could also possibly be organellar (mitochondrial). A transit peptide cannot be excluded in the sequence.. Localization: Mitochondrial (by feature)
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 8 |
| NetGPI | no | yes: 0, no: 8 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005739 | mitochondrion | 5 | 4 |
| GO:0016020 | membrane | 2 | 8 |
| GO:0043226 | organelle | 2 | 4 |
| GO:0043227 | membrane-bounded organelle | 3 | 4 |
| GO:0043229 | intracellular organelle | 3 | 4 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 4 |
| GO:0110165 | cellular anatomical entity | 1 | 8 |
Related structures:
AlphaFold database: A4H5R7
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0008535 | respiratory chain complex IV assembly | 7 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016043 | cellular component organization | 3 | 1 |
| GO:0017004 | cytochrome complex assembly | 6 | 1 |
| GO:0022607 | cellular component assembly | 4 | 1 |
| GO:0033108 | mitochondrial respiratory chain complex assembly | 6 | 1 |
| GO:0033617 | mitochondrial cytochrome c oxidase assembly | 7 | 1 |
| GO:0043933 | protein-containing complex organization | 4 | 1 |
| GO:0065003 | protein-containing complex assembly | 5 | 1 |
| GO:0071840 | cellular component organization or biogenesis | 2 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 27 | 29 | PF00675 | 0.383 |
| CLV_NRD_NRD_1 | 54 | 56 | PF00675 | 0.569 |
| CLV_PCSK_FUR_1 | 52 | 56 | PF00082 | 0.592 |
| CLV_PCSK_KEX2_1 | 22 | 24 | PF00082 | 0.428 |
| CLV_PCSK_KEX2_1 | 27 | 29 | PF00082 | 0.404 |
| CLV_PCSK_KEX2_1 | 54 | 56 | PF00082 | 0.569 |
| CLV_PCSK_KEX2_1 | 6 | 8 | PF00082 | 0.479 |
| CLV_PCSK_PC1ET2_1 | 22 | 24 | PF00082 | 0.522 |
| CLV_PCSK_PC1ET2_1 | 6 | 8 | PF00082 | 0.485 |
| CLV_PCSK_PC7_1 | 23 | 29 | PF00082 | 0.419 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.636 |
| DOC_ANK_TNKS_1 | 26 | 33 | PF00023 | 0.393 |
| DOC_CYCLIN_RxL_1 | 65 | 79 | PF00134 | 0.359 |
| DOC_MAPK_gen_1 | 67 | 75 | PF00069 | 0.402 |
| DOC_PP2B_LxvP_1 | 75 | 78 | PF13499 | 0.435 |
| DOC_PP4_FxxP_1 | 21 | 24 | PF00568 | 0.519 |
| LIG_LIR_Nem_3 | 85 | 90 | PF02991 | 0.522 |
| LIG_Pex14_1 | 42 | 46 | PF04695 | 0.206 |
| LIG_SH2_CRK | 87 | 91 | PF00017 | 0.301 |
| LIG_SH2_STAT5 | 4 | 7 | PF00017 | 0.676 |
| LIG_SH2_STAT5 | 45 | 48 | PF00017 | 0.470 |
| LIG_SH2_STAT5 | 8 | 11 | PF00017 | 0.672 |
| MOD_CK1_1 | 11 | 17 | PF00069 | 0.565 |
| MOD_GSK3_1 | 92 | 99 | PF00069 | 0.440 |
| MOD_PK_1 | 55 | 61 | PF00069 | 0.370 |
| MOD_PKA_1 | 22 | 28 | PF00069 | 0.707 |
| MOD_PKA_2 | 22 | 28 | PF00069 | 0.700 |
| MOD_PKA_2 | 95 | 101 | PF00069 | 0.360 |
| TRG_ENDOCYTIC_2 | 41 | 44 | PF00928 | 0.283 |
| TRG_ENDOCYTIC_2 | 87 | 90 | PF00928 | 0.398 |
| TRG_ER_diArg_1 | 27 | 29 | PF00400 | 0.587 |
| TRG_ER_diArg_1 | 52 | 55 | PF00400 | 0.438 |
| TRG_ER_diArg_1 | 68 | 71 | PF00400 | 0.433 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P760 | Leptomonas seymouri | 72% | 100% |
| A0A0S4IM31 | Bodo saltans | 44% | 81% |
| A0A3S5H6E0 | Leishmania donovani | 81% | 95% |
| A4HU07 | Leishmania infantum | 81% | 95% |
| D0A9H2 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 59% | 100% |
| E9AMT7 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 81% | 95% |
| Q4QHT8 | Leishmania major | 81% | 100% |