Serine/arginine repetitive matrix protein 2-like

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H5Q1_LEIBR

TriTrypDb:

LbrM.09.0780 , LBRM2903_090013000

Length:

453

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5Q1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5Q1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	211	213	PF00675	0.607
CLV_NRD_NRD_1	218	220	PF00675	0.633
CLV_NRD_NRD_1	293	295	PF00675	0.574
CLV_NRD_NRD_1	91	93	PF00675	0.570
CLV_PCSK_FUR_1	163	167	PF00082	0.773
CLV_PCSK_FUR_1	209	213	PF00082	0.563
CLV_PCSK_KEX2_1	165	167	PF00082	0.742
CLV_PCSK_KEX2_1	211	213	PF00082	0.633
CLV_PCSK_KEX2_1	218	220	PF00082	0.623
CLV_PCSK_KEX2_1	240	242	PF00082	0.643
CLV_PCSK_KEX2_1	285	287	PF00082	0.590
CLV_PCSK_KEX2_1	293	295	PF00082	0.535
CLV_PCSK_KEX2_1	90	92	PF00082	0.760
CLV_PCSK_PC1ET2_1	165	167	PF00082	0.705
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.746
CLV_PCSK_PC1ET2_1	285	287	PF00082	0.590
CLV_PCSK_PC7_1	281	287	PF00082	0.589
CLV_PCSK_SKI1_1	159	163	PF00082	0.602
CLV_PCSK_SKI1_1	240	244	PF00082	0.645
CLV_PCSK_SKI1_1	5	9	PF00082	0.528
DEG_APCC_DBOX_1	292	300	PF00400	0.567
DEG_SPOP_SBC_1	287	291	PF00917	0.569
DOC_ANK_TNKS_1	123	130	PF00023	0.581
DOC_USP7_MATH_1	111	115	PF00917	0.745
DOC_USP7_MATH_1	266	270	PF00917	0.717
DOC_USP7_MATH_1	64	68	PF00917	0.677
DOC_USP7_UBL2_3	136	140	PF12436	0.579
DOC_WW_Pin1_4	167	172	PF00397	0.552
DOC_WW_Pin1_4	194	199	PF00397	0.753
DOC_WW_Pin1_4	247	252	PF00397	0.692
DOC_WW_Pin1_4	300	305	PF00397	0.702
DOC_WW_Pin1_4	342	347	PF00397	0.582
DOC_WW_Pin1_4	349	354	PF00397	0.565
DOC_WW_Pin1_4	394	399	PF00397	0.741
DOC_WW_Pin1_4	430	435	PF00397	0.821
DOC_WW_Pin1_4	441	446	PF00397	0.592
DOC_WW_Pin1_4	55	60	PF00397	0.802
DOC_WW_Pin1_4	84	89	PF00397	0.709
LIG_14-3-3_CanoR_1	176	185	PF00244	0.560
LIG_14-3-3_CanoR_1	286	296	PF00244	0.747
LIG_14-3-3_CanoR_1	311	318	PF00244	0.578
LIG_FHA_1	408	414	PF00498	0.802
LIG_GBD_Chelix_1	22	30	PF00786	0.609
LIG_HCF-1_HBM_1	307	310	PF13415	0.493
LIG_Integrin_isoDGR_2	331	333	PF01839	0.532
LIG_LIR_Gen_1	444	453	PF02991	0.534
LIG_LIR_Nem_3	352	358	PF02991	0.714
LIG_LIR_Nem_3	444	450	PF02991	0.539
LIG_LIR_Nem_3	80	84	PF02991	0.657
LIG_PDZ_Class_2	448	453	PF00595	0.529
LIG_Pex14_1	306	310	PF04695	0.523
LIG_PTB_Apo_2	75	82	PF02174	0.531
LIG_PTB_Phospho_1	75	81	PF10480	0.530
LIG_SH2_CRK	355	359	PF00017	0.723
LIG_SH2_STAT3	388	391	PF00017	0.585
LIG_SH3_3	255	261	PF00018	0.560
LIG_SH3_3	340	346	PF00018	0.687
LIG_SH3_3	421	427	PF00018	0.665
LIG_SUMO_SIM_anti_2	65	70	PF11976	0.534
LIG_SUMO_SIM_par_1	67	72	PF11976	0.627
MOD_CDC14_SPxK_1	87	90	PF00782	0.564
MOD_CDK_SPxK_1	84	90	PF00069	0.748
MOD_CDK_SPxxK_3	167	174	PF00069	0.555
MOD_CDK_SPxxK_3	84	91	PF00069	0.749
MOD_CK1_1	16	22	PF00069	0.642
MOD_CK1_1	249	255	PF00069	0.565
MOD_CK1_1	259	265	PF00069	0.721
MOD_CK1_1	269	275	PF00069	0.517
MOD_CK1_1	361	367	PF00069	0.770
MOD_CK1_1	373	379	PF00069	0.621
MOD_CK1_1	404	410	PF00069	0.647
MOD_CK1_1	411	417	PF00069	0.520
MOD_CK1_1	441	447	PF00069	0.549
MOD_CK1_1	80	86	PF00069	0.767
MOD_CK2_1	135	141	PF00069	0.685
MOD_CK2_1	55	61	PF00069	0.597
MOD_CK2_1	97	103	PF00069	0.570
MOD_GlcNHglycan	125	128	PF01048	0.710
MOD_GlcNHglycan	15	18	PF01048	0.553
MOD_GlcNHglycan	219	222	PF01048	0.442
MOD_GlcNHglycan	251	254	PF01048	0.604
MOD_GlcNHglycan	261	264	PF01048	0.780
MOD_GlcNHglycan	271	274	PF01048	0.680
MOD_GlcNHglycan	376	379	PF01048	0.731
MOD_GlcNHglycan	398	401	PF01048	0.739
MOD_GlcNHglycan	71	74	PF01048	0.578
MOD_GlcNHglycan	99	102	PF01048	0.721
MOD_GSK3_1	111	118	PF00069	0.819
MOD_GSK3_1	119	126	PF00069	0.628
MOD_GSK3_1	127	134	PF00069	0.649
MOD_GSK3_1	136	143	PF00069	0.670
MOD_GSK3_1	249	256	PF00069	0.784
MOD_GSK3_1	288	295	PF00069	0.710
MOD_GSK3_1	306	313	PF00069	0.564
MOD_GSK3_1	331	338	PF00069	0.742
MOD_GSK3_1	359	366	PF00069	0.703
MOD_GSK3_1	370	377	PF00069	0.773
MOD_GSK3_1	396	403	PF00069	0.712
MOD_GSK3_1	404	411	PF00069	0.706
MOD_GSK3_1	425	432	PF00069	0.662
MOD_GSK3_1	439	446	PF00069	0.698
MOD_GSK3_1	80	87	PF00069	0.621
MOD_GSK3_1	97	104	PF00069	0.554
MOD_N-GLC_1	119	124	PF02516	0.595
MOD_N-GLC_1	136	141	PF02516	0.755
MOD_N-GLC_1	199	204	PF02516	0.626
MOD_N-GLC_1	287	292	PF02516	0.769
MOD_N-GLC_1	373	378	PF02516	0.668
MOD_N-GLC_1	430	435	PF02516	0.590
MOD_NEK2_1	135	140	PF00069	0.578
MOD_NEK2_1	154	159	PF00069	0.515
MOD_NEK2_1	161	166	PF00069	0.597
MOD_NEK2_1	358	363	PF00069	0.772
MOD_NEK2_1	408	413	PF00069	0.672
MOD_NEK2_2	266	271	PF00069	0.674
MOD_PIKK_1	111	117	PF00454	0.632
MOD_PIKK_1	408	414	PF00454	0.585
MOD_PKA_1	91	97	PF00069	0.781
MOD_PKA_2	123	129	PF00069	0.698
MOD_PKA_2	217	223	PF00069	0.629
MOD_PKA_2	259	265	PF00069	0.643
MOD_PKA_2	292	298	PF00069	0.823
MOD_PKA_2	310	316	PF00069	0.495
MOD_PKA_2	425	431	PF00069	0.588
MOD_PKA_2	91	97	PF00069	0.822
MOD_PKB_1	90	98	PF00069	0.575
MOD_Plk_1	140	146	PF00069	0.814
MOD_Plk_1	199	205	PF00069	0.619
MOD_Plk_1	306	312	PF00069	0.498
MOD_Plk_1	438	444	PF00069	0.808
MOD_Plk_1	53	59	PF00069	0.597
MOD_Plk_1	64	70	PF00069	0.454
MOD_Plk_4	64	70	PF00069	0.532
MOD_ProDKin_1	167	173	PF00069	0.553
MOD_ProDKin_1	194	200	PF00069	0.757
MOD_ProDKin_1	247	253	PF00069	0.696
MOD_ProDKin_1	300	306	PF00069	0.699
MOD_ProDKin_1	342	348	PF00069	0.582
MOD_ProDKin_1	349	355	PF00069	0.566
MOD_ProDKin_1	394	400	PF00069	0.741
MOD_ProDKin_1	430	436	PF00069	0.821
MOD_ProDKin_1	441	447	PF00069	0.591
MOD_ProDKin_1	55	61	PF00069	0.801
MOD_ProDKin_1	84	90	PF00069	0.711
MOD_SUMO_rev_2	19	29	PF00179	0.527
TRG_DiLeu_BaEn_4	438	444	PF01217	0.557
TRG_DiLeu_BaLyEn_6	157	162	PF01217	0.603
TRG_ENDOCYTIC_2	355	358	PF00928	0.722
TRG_ER_diArg_1	142	145	PF00400	0.687
TRG_ER_diArg_1	173	176	PF00400	0.704
TRG_ER_diArg_1	182	185	PF00400	0.611
TRG_ER_diArg_1	209	212	PF00400	0.621
TRG_ER_diArg_1	217	219	PF00400	0.607
TRG_ER_diArg_1	90	92	PF00400	0.576
TRG_Pf-PMV_PEXEL_1	186	190	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	20	24	PF00026	0.423
TRG_Pf-PMV_PEXEL_1	212	216	PF00026	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ65	Leptomonas seymouri	32%	76%
A0A3S7WQN7	Leishmania donovani	44%	88%
A4HTZ1	Leishmania infantum	44%	88%
E9AMS1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	88%
Q4QHV4	Leishmania major	42%	100%