Putative prefoldin subunit 2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

prefoldin subunit 2, putative

Species:

Leishmania braziliensis

UniProt:

A4H5P8_LEIBR

TriTrypDb:

LbrM.09.0750 , LBRM2903_090012400

Length:

230

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016272	prefoldin complex	2	2
GO:0032991	protein-containing complex	1	2

Expansion

Sequence features

A4H5P8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5P8

Function

Biological processes
Term	Name	Level	Count
GO:0006457	protein folding	2	2
GO:0009987	cellular process	1	2

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0005515	protein binding	2	2
GO:0051082	unfolded protein binding	3	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	90	92	PF00675	0.869
CLV_PCSK_SKI1_1	181	185	PF00082	0.500
CLV_PCSK_SKI1_1	226	230	PF00082	0.859
CLV_PCSK_SKI1_1	69	73	PF00082	0.824
DEG_APCC_DBOX_1	180	188	PF00400	0.700
DEG_Nend_UBRbox_4	1	3	PF02207	0.837
DOC_CKS1_1	1	6	PF01111	0.823
DOC_CYCLIN_yCln2_LP_2	59	65	PF00134	0.819
DOC_MAPK_DCC_7	5	15	PF00069	0.814
DOC_PP2B_LxvP_1	34	37	PF13499	0.829
DOC_PP2B_LxvP_1	59	62	PF13499	0.821
DOC_USP7_MATH_1	122	126	PF00917	0.700
DOC_USP7_MATH_1	218	222	PF00917	0.874
DOC_USP7_MATH_1	97	101	PF00917	0.862
LIG_14-3-3_CanoR_1	91	99	PF00244	0.874
LIG_Actin_WH2_2	173	190	PF00022	0.700
LIG_BRCT_BRCA1_1	11	15	PF00533	0.811
LIG_BRCT_BRCA1_1	67	71	PF00533	0.813
LIG_CtBP_PxDLS_1	10	14	PF00389	0.802
LIG_EVH1_2	29	33	PF00568	0.817
LIG_FHA_1	202	208	PF00498	0.818
LIG_FHA_2	1	7	PF00498	0.823
LIG_FHA_2	163	169	PF00498	0.700
LIG_LIR_Gen_1	12	20	PF02991	0.823
LIG_LIR_Gen_1	31	39	PF02991	0.491
LIG_LIR_LC3C_4	31	36	PF02991	0.823
LIG_LIR_Nem_3	12	18	PF02991	0.822
LIG_LIR_Nem_3	31	36	PF02991	0.491
LIG_LIR_Nem_3	68	74	PF02991	0.819
LIG_PDZ_Class_2	225	230	PF00595	0.857
LIG_SH3_3	24	30	PF00018	0.461
LIG_SH3_3	4	10	PF00018	0.813
LIG_SUMO_SIM_par_1	160	165	PF11976	0.700
MOD_CK1_1	100	106	PF00069	0.806
MOD_CK1_1	14	20	PF00069	0.823
MOD_CK1_1	219	225	PF00069	0.866
MOD_CK2_1	100	106	PF00069	0.806
MOD_CK2_1	162	168	PF00069	0.700
MOD_GlcNHglycan	119	123	PF01048	0.500
MOD_GlcNHglycan	87	90	PF01048	0.862
MOD_GlcNHglycan	93	96	PF01048	0.775
MOD_GSK3_1	118	125	PF00069	0.700
MOD_GSK3_1	214	221	PF00069	0.875
MOD_N-GLC_1	131	136	PF02516	0.500
MOD_NEK2_1	201	206	PF00069	0.808
MOD_NEK2_1	65	70	PF00069	0.808
MOD_PIKK_1	182	188	PF00454	0.700
MOD_PIKK_1	216	222	PF00454	0.875
MOD_PKA_1	91	97	PF00069	0.876
MOD_Plk_1	118	124	PF00069	0.700
MOD_Plk_1	162	168	PF00069	0.700
MOD_Plk_4	11	17	PF00069	0.816
MOD_Plk_4	28	34	PF00069	0.521
MOD_SUMO_rev_2	88	94	PF00179	0.868
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.832
TRG_ENDOCYTIC_2	113	116	PF00928	0.700
TRG_Pf-PMV_PEXEL_1	145	150	PF00026	0.500
TRG_Pf-PMV_PEXEL_1	189	193	PF00026	0.500

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A1A4P5	BOVIN	37%	100%
A8WVJ9	CAEBR	31%	100%
B0BN18	RAT	38%	100%
O70591	MOUSE	39%	100%
P40005	YEAST	28%	100%
Q55GN3	DICDI	42%	100%
Q9LJ98	ARATH	35%	100%
Q9N5M2	CAEEL	32%	100%
Q9UHV9	HUMAN	37%	100%
Q9UTC9	SCHPO	35%	100%
Q9VTE5	DROME	30%	100%